The Oncosearch | Oncotarget

CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer Research Paper

Allison Makovec, John T. Phoenix, Hannah E. Bergom, Ella Boytim, Ava P. Gustafson, Aiden Deacon, Sydney Tape, Atef Ali, Megan Ludwig, Samuel P. Pitzen, David Moline, Camden Richter, Hudson Longie, Mei-Chi Su, Sampreeti Jena, Pornlada Likasitwatanakul, Justin M. Drake, R. Stephanie Huang, William C. Hahn, Jonathan P. Rennhack, Scott M. Dehm, Steven Kregel, Emmanuel S. Antonarakis, Justin Hwang

Published Mar 30, 2026 · Vol. 17, No. 1 · pp. 59-73

Keywords: prostate cancer, CREB5, basal-like, stem cell-like, AP-1 transcription factors

LRIG1-3 in gliomas: LRIG1 protein expression decreased in higher grade gliomas Research Paper

Marlene Happe, Saskia Kuhl, Lukas Görtz, Roland Goldbrunner, Marco Timmer

Published Oct 27, 2025 · Vol. 16, No. 1 · pp. 793-807

Keywords: glioma, glioblastoma, LRIG1, LRIG2, LRIG3

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

Kristen Kwong, Yue Pan, Jacqueline Morales, Matthew Watson, David V. Allegakoen, Alex G. Lee, Trever G. Bivona, Peter Wipf, Christopher J. Guerriero, Jeffrey L. Brodsky, Amit J. Sabnis

Published Aug 23, 2025 · Vol. 16, No. 1 · pp. 681-696

Keywords: protein homeostasis, rhabdomyosarcoma, unfolded protein response, preclinical therapeutics, p97

Dissecting the functional differences and clinical features of R-spondin family members in metastatic prostate cancer Research Paper

Aiden Deacon, Ava Gustafson, Allison Makovec, Ella Boytim, Gabriella von Dohlen, David Moline, Elin Kairies, Sam Kellen, Khalid Ishani, Megan L. Ludwig, Emily John, Alexis Anike, Hai Dang Nguyen, Scott M. Dehm, Justin M. Drake, Emmanuel S. Antonarakis, Justin Hwang

Published Jul 19, 2025 · Vol. 16, No. 1 · pp. 606-620

Keywords: RSPO2, prostate cancer, Wnt signaling, genomics, therapeutics

Hypoxia induced lipid droplet accumulation promotes resistance to ferroptosis in prostate cancer Research Paper

Shailender S. Chauhan, Andres D. Vizzerra, Hope Liou, Caitlyn E. Flores, Ashley J. Snider, Justin M. Snider, Noel A. Warfel

Published Jun 18, 2025 · Vol. 16, No. 1 · pp. 532-544

Keywords: hypoxia, lipid droplets, ferroptosis, resistance, prostate

Targeting PCNA/AR interaction inhibits AR-mediated signaling in castration resistant prostate cancer cells Research Paper

Shan Lu, Zhongyun Dong

Published May 8, 2025 · Vol. 16, No. 1 · pp. 383-395

Keywords: PCNA, androgen receptor, PCNA inhibitors, AR splicing variants, CRPC

NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma Research Paper

Andrea Gunnell, Scott T. Kimber, Richard Houlston, Martin Kaiser

Published Mar 16, 2025 · Vol. 16, No. 1 · pp. 220-229

Keywords: myeloma, NSD2, t(4;14), CD38, plasma cell

FGR Src family kinase causes signaling and phenotypic shift mimicking retinoic acid-induced differentiation of leukemic cells Research Paper

Noor Kazim, Wang Peng, Jianbo Yue, Andrew Yen

Published Mar 14, 2025 · Vol. 16, No. 1 · pp. 202-218

Keywords: cancer biology and cell cycle regulation, retinoic acid(RA), FGR Src-family-kinase, cancer differentiation-therapy, leukemia

Robust p53 phenotypes and prospective downstream targets in telomerase-immortalized human cells Research Paper

Jessica J. Miciak, Lucy Petrova, Rhythm Sajwan, Aditya Pandya, Mikayla Deckard, Andrew J. Munoz, Fred Bunz

Published Feb 6, 2025 · Vol. 16, No. 1 · pp. 79-100

Keywords: p53, ionizing radiation, immortalized cells, ALDH3A1, NECTIN4

Trained and ready - the case for an inflammatory memory for hematopoietic stem and progenitor cells in the AML niche Research Perspective

Ding-Wen Chen, Eric K. Wafula, Peter Kurre

Published Aug 17, 2024 · Vol. 15, No. 1 · pp. 609-613

Keywords: hematopoietic stem and progenitor cells, acute myeloid leukemia, inflammation, innate immune reprogramming, trained immunity

Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties Research Paper

Alan Halim, Nasreen Al-Qadi, Elizabeth Kenyon, Kayla N. Conner, Sujan Kumar Mondal, Zdravka Medarova, Anna Moore

Published Aug 17, 2024 · Vol. 15, No. 1 · pp. 591-606

Keywords: breast cancer, metastasis, stem-like cells, nanoparticle, miR-10b

Integrated stress response (ISR) activation and apoptosis through HRI kinase by PG3 and other p53 pathway-restoring cancer therapeutics Research Paper

Xiaobing Tian, Wafik S. El-Deiry

Published Jul 26, 2024 · Vol. 15, No. 1 · pp. 614-633

Keywords: mutant p53, integrated stress response (ISR), ATF4, HRI, ClpP

Targeting WNT5B and WNT10B in osteosarcoma Review

Gustavo A. Miranda-Carboni, Susan A. Krum

Published Jul 18, 2024 · Vol. 15, No. 1 · pp. 535-540

Keywords: WNT5B, WNT10B, WNT signaling, osteosarcoma

Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure Research Paper

Shengliang Zhang, Wafik S. El-Deiry

Published Apr 29, 2024 · Vol. 15, No. 1 · pp. 275-284

Keywords: SARS-COV2 spike, p53, MDM2, chemotherapy, cancer

AGO2 in T-prolymphocytic leukemia: its canonical and non-canonical deregulation and function Editorial

Till Braun, Hanna Klepzig, Marco Herling

Published Feb 28, 2023 · Vol. 14, No. 1 · pp. 395-397

Keywords: T-PLL, AGO2, microRNA

The nuclear envelope and metastasis Editorial

Emily Hansen, James M. Holaska

Published Feb 17, 2023 · Vol. 14, No. 1 · pp. 317-320

Keywords: emerin, metastasis, mechanotransduction, breast cancer, nucleoskeleton

PACER lncRNA regulates COX-2 expression in lung cancer cells Research Paper

Samuel Z. Desind, Joseph R. Iacona, Christina Y. Yu, Antonina Mitrofanova, Carol S. Lutz

Published Jan 29, 2022 · Vol. 13, No. 1 · pp. 291-306

Keywords: PACER, COX-2, PGE₂, lung adenocarcinoma, inflammation

Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models Research Paper

Lindsay R. Stolzenburg, Barrett Ainsworth, Bridget Riley-Gillis, Tibor Pakozdi, Areej Ammar, Paul A. Ellis, Julie L. Wilsbacher, Cyril Y. Ramathal

Published Dec 17, 2021 · Vol. 13, No. 1 · pp. 1-12

Keywords: PARP inhibitor, veliparib, cisplatin, transcriptomics, NSCLC

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper

Edmond J. Feris, John W. Hinds, Michael D. Cole

Published Sep 11, 2021 · Vol. 12, No. 21 · pp. 2147-2157

Keywords: cancer, drug discovery, targeted therapy, oncogene, transcription factor

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Erling Håland, Ingrid Nyhus Moen, Elias Veidal, Hanne Hella, Kristine Misund, Tobias S. Slørdahl, Kristian K. Starheim

Published Sep 4, 2021 · Vol. 12, No. 21 · pp. 2158-2168

Keywords: multiple myeloma, TAK1, apoptosis, NF-κB, cancer treatment

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CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer Research Paper

LRIG1-3 in gliomas: LRIG1 protein expression decreased in higher grade gliomas Research Paper

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

Dissecting the functional differences and clinical features of R-spondin family members in metastatic prostate cancer Research Paper

Hypoxia induced lipid droplet accumulation promotes resistance to ferroptosis in prostate cancer Research Paper

Targeting PCNA/AR interaction inhibits AR-mediated signaling in castration resistant prostate cancer cells Research Paper

NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma Research Paper

FGR Src family kinase causes signaling and phenotypic shift mimicking retinoic acid-induced differentiation of leukemic cells Research Paper

Robust p53 phenotypes and prospective downstream targets in telomerase-immortalized human cells Research Paper

Trained and ready - the case for an inflammatory memory for hematopoietic stem and progenitor cells in the AML niche Research Perspective

Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties Research Paper

Integrated stress response (ISR) activation and apoptosis through HRI kinase by PG3 and other p53 pathway-restoring cancer therapeutics Research Paper

Targeting WNT5B and WNT10B in osteosarcoma Review

Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure Research Paper

AGO2 in T-prolymphocytic leukemia: its canonical and non-canonical deregulation and function Editorial

The nuclear envelope and metastasis Editorial

PACER lncRNA regulates COX-2 expression in lung cancer cells Research Paper

Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models Research Paper

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer Research Paper

LRIG1-3 in gliomas: LRIG1 protein expression decreased in higher grade gliomas Research Paper

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

Dissecting the functional differences and clinical features of R-spondin family members in metastatic prostate cancer Research Paper

Hypoxia induced lipid droplet accumulation promotes resistance to ferroptosis in prostate cancer Research Paper

Targeting PCNA/AR interaction inhibits AR-mediated signaling in castration resistant prostate cancer cells Research Paper

NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma Research Paper

FGR Src family kinase causes signaling and phenotypic shift mimicking retinoic acid-induced differentiation of leukemic cells Research Paper

Robust p53 phenotypes and prospective downstream targets in telomerase-immortalized human cells Research Paper

Trained and ready - the case for an inflammatory memory for hematopoietic stem and progenitor cells in the AML niche Research Perspective

Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties Research Paper

Integrated stress response (ISR) activation and apoptosis through HRI kinase by PG3 and other p53 pathway-restoring cancer therapeutics Research Paper

Targeting WNT5B and WNT10B in osteosarcoma Review

Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure Research Paper

AGO2 in T-prolymphocytic leukemia: its canonical and non-canonical deregulation and function Editorial

The nuclear envelope and metastasis Editorial

PACER lncRNA regulates COX-2 expression in lung cancer cells Research Paper

Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models Research Paper

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper