The Oncosearch | Oncotarget

Semi-synthetic ocotillol analogues as selective ABCB1-mediated drug resistance reversal agents Research Paper

Yun-Kai Zhang, Hengyuan Zhang, Guan-Nan Zhang, Yi-Jun Wang, Rishil J. Kathawala, Rui Si, Bhargav A. Patel, Jinyi Xu, Zhe-Sheng Chen

Published Jul 4, 2015 · Vol. 6, No. 27 · pp. 24277-24290

High-throughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von Hippel-Lindau loss in renal cell carcinoma Priority Research Paper

Nicholas C. Wolff, Andrea PavÃa-JimÃ©nez, Vanina T. Tcheuyap, Shane Alexander, Mridula Vishwanath, Alana Christie, Xian-Jin Xie, Noelle S. Williams, Payal Kapur, Bruce Posner, RenÃ©e M. McKay, James Brugarolas

Published Jul 3, 2015 · Vol. 6, No. 19 · pp. 16951-16962

High EGFR and low p-Akt expression is associated with better outcome after nimotuzumab-containing treatment in esophageal cancer patients: preliminary clinical result and testable hypothesis Clinical Research Papers

Chun-yu Wang, Jia-ying Deng, Xu-wei Cai, Xiao-long Fu, Yuan Li, Xiao-yan Zhou, Xiang-hua Wu, Xi-chun Hu, Min Fan, Jia-qing Xiang, Ya-wei Zhang, Hai-quan Chen, Rolando Perez, Guo-liang Jiang, Kuai-le Zhao

Published Jun 8, 2015 · Vol. 6, No. 21 · pp. 18674-18682

Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion Priority Research Paper

Huabo Wang, Lokendra Sharma, Jie Lu, Paul Finch, Steven Fletcher, Edward V. Prochownik

Published May 30, 2015 · Vol. 6, No. 18 · pp. 15857-15870

Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition Review

Didier. RÃ©mond, Danit R. Shahar, Doreen Gille, Paula Pinto, Josefa Kachal, Marie-AgnÃ¨s Peyron, Claudia Nunes Dos Santos, Barbara Walther, Alessandra Bordoni, Didier Dupont, Lidia TomÃ¡s-Cobos, Guy VergÃ¨res

Published May 27, 2015 · Vol. 6, No. 16 · pp. 13858-13898

Ca²⁺ influx-mediated dilation of the endoplasmic reticulum and c-FLIP_L downregulation trigger CDDO-Me-induced apoptosis in breast cancer cells Research Paper

Soo Ah Jeong, In Young Kim, A Reum Lee, Mi Jin Yoon, Hyeseong Cho, Jong-Soo Lee, Kyeong Sook Choi

Published May 25, 2015 · Vol. 6, No. 25 · pp. 21173-21192

Oral nano-delivery of anticancer ginsenoside 25-OCH₃-PPD, a natural inhibitor of the MDM2 oncogene: Nanoparticle preparation, characterization, in vitro and in vivo anti-prostate cancer activity, and mechanisms of action Research Paper

Sukesh Voruganti, Jiang-Jiang Qin, Sushanta Sarkar, Subhasree Nag, Ismail A. Walbi, Shu Wang, Yuqing Zhao, Wei Wang, Ruiwen Zhang

Published May 24, 2015 · Vol. 6, No. 25 · pp. 21379-21394

Liposome encapsulated curcumin-difluorinated (CDF) inhibits the growth of cisplatin resistant head and neck cancer stem cells Research Paper

Saroj K. Basak, Alborz Zinabadi, Arthur W. Wu, Natarajan Venkatesan, Victor M. Duarte, James J. Kang, Clifton L. Dalgard, Meera Srivastava, Fazlul H. Sarkar, Marilene B. Wang, Eri S. Srivatsan

Published May 19, 2015 · Vol. 6, No. 21 · pp. 18504-18517

Endoplasmic reticulum targeting in Ewingâ€™s sarcoma by the alkylphospholipid analog edelfosine Research Paper

Ximena Bonilla, EL-Habib Dakir, Faustino Mollinedo, Consuelo Gajate

Published May 9, 2015 · Vol. 6, No. 16 · pp. 14596-14613

Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance Research Paper

JesÃºs GarcÃa-Cano, Gorbatchev Ambroise, Raquel Pascual-Serra, M Carmen CarriÃ³n, Leticia Serrano-Oviedo, Marta Ortega-Muelas, Francisco J. Cimas, SebastiÃ Sabater, MarÃa JosÃ© Ruiz-Hidalgo, Isabel Sanchez Perez, Antonio Mas, FÃ©lix A. JalÃ³n, AimÃ© Vazquez, Ricardo SÃ¡nchez-Prieto

Published May 6, 2015 · Vol. 6, No. 17 · pp. 15551-15565

Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition Priority Research Paper

Ying Shen, Jie Li, Masayuki Nitta, Diahnn Futalan, Tyler Steed, Jeffrey M. Treiber, Zack Taich, Deanna Stevens, Jill Wykosky, Hong-Zhuan Chen, Bob S. Carter, Oren J. Becher, Richard Kennedy, Fumiko Esashi, Jann N. Sarkaria, Frank B. Furnari, Webster K. Cavenee, Arshad Desai, Clark C. Chen

Published May 5, 2015 · Vol. 6, No. 14 · pp. 11751-11767

OVOL guides the epithelial-hybrid-mesenchymal transition Research Paper

Dongya Jia, Mohit Kumar Jolly, Marcelo Boareto, Princy Parsana, Steven M. Mooney, Kenneth J. Pienta, Herbert Levine, Eshel Ben-Jacob

Published Apr 22, 2015 · Vol. 6, No. 17 · pp. 15436-15448

Deregulation of PPARÎ²/Î´ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment Research Paper

Tim Schumann, Till Adhikary, Annika Wortmann, Florian Finkernagel, Sonja Lieber, Evelyn Schnitzer, Nathalie Legrand, Yvonne Schober, W. Andreas Nockher, Philipp M. Toth, Wibke E. Diederich, Andrea Nist, Thorsten Stiewe, Uwe Wagner, Silke Reinartz, Sabine MÃ¼ller-BrÃ¼sselbach, Rolf MÃ¼ller

Published Apr 15, 2015 · Vol. 6, No. 15 · pp. 13416-13433

Expansion of myeloid-derived suppressor cells with arginase activity lasts longer in aged than in young mice after CpG-ODN plus IFA treatment Research Paper

MarÃa F. Harman, Romina P. Ranocchia, Carolina V. Gorlino, MarÃa F. SÃ¡nchez Vallecillo, SofÃa D. Castell, MarÃa I. Crespo, Belkys A. Maletto, Gabriel MorÃ³n, MarÃa C. Pistoresi-Palencia

Published Apr 13, 2015 · Vol. 6, No. 15 · pp. 13448-13461

Autoimmune response to PARP and BRCA1/BRCA2 in cancer Research Paper

Qing Zhu, Su-Xia Han, Cong-Ya Zhou, Meng-Jiao Cai, Li-Ping Dai, Jian-Ying Zhang

Published Mar 24, 2015 · Vol. 6, No. 13 · pp. 11575-11584

Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma Research Paper

Ulrike Graab, Heidi Hahn, Simone Fulda

Published Mar 6, 2015 · Vol. 6, No. 11 · pp. 8722-8735

Keywords: apoptosis, hedgehog, PI3K, rhabdomyosarcoma

A novel cancer immunotherapy based on the combination of a synthetic carbohydrate-pulsed dendritic cell vaccine and glycoengineered cancer cells Research Paper

Lei Qiu, Jie Li, Shichong Yu, Qianli Wang, Yinghua Li, Zhenlin Hu, Qiuye Wu, Zhongwu Guo, Junping Zhang

Published Mar 4, 2015 · Vol. 6, No. 7 · pp. 5195-5203

Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo Research Paper

Ming-Hui Lee, Wan-Pei Su, Wan-Jen Wang, Sing-Ru Lin, Chen-Yu Lu, Yu-An Chen, Jean-Yun Chang, Shenq-Shyang Huang, Pei-Yi Chou, Siou-Ru Ye, Szu-Jung Chen, Huan He, Ting-Hsiu Liu, Ying-Tsen Chou, Li-Jin Hsu, Feng-Jie Lai, Shean-Jen Chen, Hoong-Chien Lee, David Kakhniashvili, Steven R. Goodman, Nan-Shan Chang

Published Feb 20, 2015 · Vol. 6, No. 6 · pp. 3737-3751

Keywords: Zfra, skin cancer, melanoma, metastasis, stemness, cancer prevention.

Shed syndecan-2 enhances tumorigenic activities of colon cancer cells Research Paper

Sojoong Choi, Youngsil Choi, Eunsung Jun, In-San Kim, Seong-Eun Kim, Sung-Ae Jung, Eok-Soo Oh

Published Feb 17, 2015 · Vol. 6, No. 6 · pp. 3874-3886

Keywords: Colon cancer, shedding, signal transduction, syndecan-2, tumorigenesis

Plasmid DNA-coding p62 as a bone effective anti-inflammatory/anabolic agent Research Paper

Maria Giovanna Sabbieti, Dimitrios Agas, Melania Capitani, Luigi Marchetti, Antonio Concetti, Cecilia Vullo, Giuseppe Catone, Vladimir Gabai, Victor Shifrin, Michael Y. Sherman, Alexander Shneider, Franco M. Venanzi

Published Feb 12, 2015 · Vol. 6, No. 6 · pp. 3590-3599

Keywords: p62 / SQSTM1, chronic inflammation, osteoporosis, immunotherapy

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Semi-synthetic ocotillol analogues as selective ABCB1-mediated drug resistance reversal agents Research Paper

High-throughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von Hippel-Lindau loss in renal cell carcinoma Priority Research Paper

High EGFR and low p-Akt expression is associated with better outcome after nimotuzumab-containing treatment in esophageal cancer patients: preliminary clinical result and testable hypothesis Clinical Research Papers

Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion Priority Research Paper

Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition Review

Ca²⁺ influx-mediated dilation of the endoplasmic reticulum and c-FLIP_L downregulation trigger CDDO-Me-induced apoptosis in breast cancer cells Research Paper

Oral nano-delivery of anticancer ginsenoside 25-OCH₃-PPD, a natural inhibitor of the MDM2 oncogene: Nanoparticle preparation, characterization, in vitro and in vivo anti-prostate cancer activity, and mechanisms of action Research Paper

Liposome encapsulated curcumin-difluorinated (CDF) inhibits the growth of cisplatin resistant head and neck cancer stem cells Research Paper

Endoplasmic reticulum targeting in Ewingâ€™s sarcoma by the alkylphospholipid analog edelfosine Research Paper

Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance Research Paper

Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition Priority Research Paper

OVOL guides the epithelial-hybrid-mesenchymal transition Research Paper

Deregulation of PPARÎ²/Î´ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment Research Paper

Expansion of myeloid-derived suppressor cells with arginase activity lasts longer in aged than in young mice after CpG-ODN plus IFA treatment Research Paper

Autoimmune response to PARP and BRCA1/BRCA2 in cancer Research Paper

Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma Research Paper

A novel cancer immunotherapy based on the combination of a synthetic carbohydrate-pulsed dendritic cell vaccine and glycoengineered cancer cells Research Paper

Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo Research Paper

Shed syndecan-2 enhances tumorigenic activities of colon cancer cells Research Paper

Plasmid DNA-coding p62 as a bone effective anti-inflammatory/anabolic agent Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Semi-synthetic ocotillol analogues as selective ABCB1-mediated drug resistance reversal agents Research Paper

High-throughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von Hippel-Lindau loss in renal cell carcinoma Priority Research Paper

High EGFR and low p-Akt expression is associated with better outcome after nimotuzumab-containing treatment in esophageal cancer patients: preliminary clinical result and testable hypothesis Clinical Research Papers

Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion Priority Research Paper

Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition Review

Ca2+ influx-mediated dilation of the endoplasmic reticulum and c-FLIPL downregulation trigger CDDO-Me-induced apoptosis in breast cancer cells Research Paper

Oral nano-delivery of anticancer ginsenoside 25-OCH3-PPD, a natural inhibitor of the MDM2 oncogene: Nanoparticle preparation, characterization, in vitro and in vivo anti-prostate cancer activity, and mechanisms of action Research Paper

Liposome encapsulated curcumin-difluorinated (CDF) inhibits the growth of cisplatin resistant head and neck cancer stem cells Research Paper

Endoplasmic reticulum targeting in Ewingâ€™s sarcoma by the alkylphospholipid analog edelfosine Research Paper

Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance Research Paper

Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition Priority Research Paper

OVOL guides the epithelial-hybrid-mesenchymal transition Research Paper

Deregulation of PPARÎ²/Î´ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment Research Paper

Expansion of myeloid-derived suppressor cells with arginase activity lasts longer in aged than in young mice after CpG-ODN plus IFA treatment Research Paper

Autoimmune response to PARP and BRCA1/BRCA2 in cancer Research Paper

Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma Research Paper

A novel cancer immunotherapy based on the combination of a synthetic carbohydrate-pulsed dendritic cell vaccine and glycoengineered cancer cells Research Paper

Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo Research Paper

Shed syndecan-2 enhances tumorigenic activities of colon cancer cells Research Paper

Plasmid DNA-coding p62 as a bone effective anti-inflammatory/anabolic agent Research Paper

Ca²⁺ influx-mediated dilation of the endoplasmic reticulum and c-FLIP_L downregulation trigger CDDO-Me-induced apoptosis in breast cancer cells Research Paper

Oral nano-delivery of anticancer ginsenoside 25-OCH₃-PPD, a natural inhibitor of the MDM2 oncogene: Nanoparticle preparation, characterization, in vitro and in vivo anti-prostate cancer activity, and mechanisms of action Research Paper