The Oncosearch | Oncotarget

Correction: Downregulation of c-SRC kinase CSK promotes castration resistant prostate cancer and pinpoints a novel disease subclass Correction

Chih-Cheng Yang, Ladan Fazli, Salvatore Loguercio, Irina Zharkikh, Pedro Aza-Blanc, Martin E. Gleave, Dieter A. Wolf

Published Feb 12, 2025 · Vol. 16, No. 1 · pp. 65-66

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death Research Paper

Chantal L. Duurland, Thijs de Gunst, Harm C. den Boer, Marion T.J. van den Bosch, Bryony J. Telford, Rogier M. Vos, Xiaolei Xie, Mingfa Zang, Fang Wang, Yingying Shao, Xiaoyu An, Jingjing Wang, Jie Cai, Ludovic Bourré, Laurens A.H. van Pinxteren, Roel Q.J. Schaapveld, Michel Janicot, Sanaz Yahyanejad

Published Jul 4, 2024 · Vol. 15, No. 1 · pp. 470-485

Keywords: miR-193a-3p, microRNA mimic, T cell mediated immunity, immunogenic cell death, cancer

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response Research Paper

Lulzim Shkreta, Johanne Toutant, Aurélie Delannoy, David Durantel, Anna Salvetti, Sophie Ehresmann, Martin Sauvageau, Julien A. Delbrouck, Alice Gravel-Trudeau, Christian Comeau, Caroline Huard, Jasmin Coulombe-Huntington, Mike Tyers, David Grierson, Pierre-Luc Boudreault, Benoit Chabot

Published May 9, 2024 · Vol. 15, No. 1 · pp. 313-325

Keywords: CLK kinases inhibitors, EMT, antiviral immune response, microtubules, metastasis

Transformation-associated recombination (TAR) cloning and its applications for gene function; genome architecture and evolution; biotechnology and biomedicine Review

Natalay Kouprina, Vladimir Larionov

Published Dec 19, 2023 · Vol. 14, No. 1 · pp. 1009-1033

Keywords: transformation-associated recombination, TAR, microbes, biomedicine, biotechnology

Targeting Ras with protein engineering Review

Atilio Tomazini, Julia M. Shifman

Published Jun 21, 2023 · Vol. 14, No. 1 · pp. 672-687

Keywords: Ras oncogene, anti-Ras therapeutics, Ras targeting, protein engineering, protein design

LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair Research Paper

Jianli Zhou, Drew Sturtevant, Cassie Love, Aditya Kulkarni, Neha Biyani, Umesh Kathad, Elizabeth Thacker, Sandeep Dave, Kishor Bhatia

Published Jun 5, 2023 · Vol. 14, No. 1 · pp. 597-611

Keywords: non-Hodgkin's lymphoma, DNA damage, homologous recombination repair, transcription-coupled nucleotide excision repair, ATM

Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival Research Paper

Jude B. Khatib, Emily M. Schleicher, Lindsey M. Jackson, Ashna Dhoonmoon, George-Lucian Moldovan, Claudia M. Nicolae

Published Sep 23, 2022 · Vol. 13, No. 1 · pp. 1078-1091

Keywords: PARP10, ATM, CRISPR screens, genome stability, cancer cell proliferation

Deciphering miR-520c-3p as a probable target for immunometabolism in non-small cell lung cancer using systems biology approach Research Paper

Pooja Gulhane, Prajakta Nimsarkar, Komal Kharat, Shailza Singh

Published May 7, 2022 · Vol. 13, No. 1 · pp. 725-746

Keywords: non-small cell lung cancer, miRNAs, miR-520c-3p, PI3K/AKT signaling pathway, therapeutic targeting

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Pratima Nangia-Makker, Malathy P.V. Shekhar, Victor Hogan, Vitaly Balan, Avraham Raz

Published Mar 9, 2022 · Vol. 13, No. 1 · pp. 534-550

Keywords: myosin II, MYH9, dNTP, deoxyribose-5-phosphate, DNA synthesis

Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity Research Paper

Daniel Menendez, Jay R. Anand, Carri C. Murphy, Whitney J. Bell, Jiaqi Fu, Nadia Slepushkina, Eugen Buehler, Scott E. Martin, Madhu Lal-Nag, John L. Nitiss, Michael A. Resnick

Published Feb 4, 2022 · Vol. 13, No. 1 · pp. 332-346

Keywords: tumor suppressor, siRNA screen, synthetic lethality, ICE assay, Top2 covalent complexes

Emerging approaches of wound healing in experimental models of high-grade oral mucositis induced by anticancer therapy Review

Ana Chor, Maria Adriana Skeff, Christina Takiya, Raquel Gonçalves, Marcos Dias, Marcos Farina, Leonardo R. Andrade, Valeria de Mello Coelho

Published Oct 1, 2021 · Vol. 12, No. 22 · pp. 2283-2299

Keywords: oral mucositis, inflammation, regeneration, polymers, tissue engineering

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Bruna Cândido Guido, Douglas Cardoso Brandão, Ana Luisa Augusto Barbosa, Monique Jacob Xavier Vianna, Lucas Faro, Luciana Machado Ramos, Fabíola Nihi, Márcio Botelho de Castro, Brenno A.D. Neto, José Raimundo Corrêa, Sônia Nair Báo

Published Aug 27, 2021 · Vol. 12, No. 19 · pp. 1920-1936

Keywords: KIF11 inhibition, Kinesin Eg5, breast cancer, adjuvant treatment, cancer progression

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Brenna M. Zimmer, Michelle E. Howell, Linlin Ma, Jeffrey R. Enders, Danielle Lehman, Eva Corey, Joseph J. Barycki, Melanie A. Simpson

Published Aug 19, 2021 · Vol. 12, No. 19 · pp. 1886-1902

Keywords: prostate cancer, castration resistance, detoxification, UDP-glucose dehydrogenase, patient-derived xenografts

Anti-aging: senolytics or gerostatics (unconventional view) Review

Mikhail V. Blagosklonny

Published Aug 12, 2021 · Vol. 12, No. 18 · pp. 1821-1835

Keywords: geroscience, senolytics, hyperfunction theory, aging, sirolimus

Role of microRNAs in glioblastoma Review

Ming Chen, Zdravka Medarova, Anna Moore

Published Jul 30, 2021 · Vol. 12, No. 17 · pp. 1707-1723

Keywords: glioblastoma, microRNA, miRNA-based therapies, miRNA delivery

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Catherine T. Haring, Chandan Bhambhani, Collin Brummel, Brittany Jewell, Emily Bellile, Molly E. Heft Neal, Erin Sandford, Ryan M. Spengler, Apurva Bhangale, Matthew E. Spector, Jonathan McHugh, Mark E. Prince, Michelle Mierzwa, Francis P. Worden, Muneesh Tewari, Paul L. Swiecicki, J. Chad Brenner

Published Jun 11, 2021 · Vol. 12, No. 13 · pp. 1214-1229

Keywords: HPV, head and neck cancer, oropharyngeal cancer, ctDNA, circulating tumor DNA

Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology Research Paper

Bryony J. Telford, Sanaz Yahyanejad, Thijs de Gunst, Harm C. den Boer, Rogier M. Vos, Marieke Stegink, Marion T.J. van den Bosch, Mir Farshid Alemdehy, Laurens A.H. van Pinxteren, Roel Q.J. Schaapveld, Michel Janicot

Published Feb 7, 2021 · Vol. 12, No. 5 · pp. 422-439

Keywords: miR-193a-3p, microRNA mimic, microRNA delivery in vivo, pleiotropic mechanism of microRNA,

Folinic acid in colorectal cancer: esquire or fellow knight? Real-world results from a mono institutional, retrospective study Research Paper

Francesco Jacopo Romano, Carmela Barbato, Maria Biglietto, Vincenzo Di Lauro, Dario Arundine, Roberto Fiorentino, Francesca Ambrosio, Maresa Cammarota, Bruno Chiurazzi, Livio Puglia, Sarah Scagliarini, Raffaella Ruocco, Carmen Mocerino, Ivana Cerillo, Maria Fiorella Brangi, Ferdinando Riccardi

Published Jan 19, 2021 · Vol. 12, No. 3 · pp. 221-229

Keywords: colorectal cancer, folinic acid, sodium levofolinate, thymidylate synthase, non oncogene addiction

Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells Research Paper

Vânia Gonçalves, Andreia F.A. Henriques, Paulo Matos, Peter Jordan

Published Nov 9, 2020 · Vol. 11, No. 47 · pp. 4421-4437

Keywords: ibuprofen, protein kinase, RAC1B, alternative splicing, colorectal cancer cells

Advances in epidermal growth factor receptor specific immunotherapy: lessons to be learned from armed antibodies Review

Fleury Augustin Nsole Biteghe, Neelakshi Mungra, Nyangone Ekome Toung Chalomie, Jean De La Croix Ndong, Jean Engohang-Ndong, Guillaume Vignaux, Eden Padayachee, Krupa Naran, Stefan Barth

Published Aug 26, 2020 · Vol. 11, No. 38 · pp. 3531-3557

Keywords: epidermal growth factor receptor (EGFR), recombinant immunotoxins (ITs), targeted human cytolytic fusion proteins (hCFPs), recombinant antibody-drug conjugates (rADCs), recombinant antibody photoimmunoconjugates (rAPCs)

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Correction: Downregulation of c-SRC kinase CSK promotes castration resistant prostate cancer and pinpoints a novel disease subclass Correction

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death Research Paper

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response Research Paper

Transformation-associated recombination (TAR) cloning and its applications for gene function; genome architecture and evolution; biotechnology and biomedicine Review

Targeting Ras with protein engineering Review

LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair Research Paper

Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival Research Paper

Deciphering miR-520c-3p as a probable target for immunometabolism in non-small cell lung cancer using systems biology approach Research Paper

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity Research Paper

Emerging approaches of wound healing in experimental models of high-grade oral mucositis induced by anticancer therapy Review

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Anti-aging: senolytics or gerostatics (unconventional view) Review

Role of microRNAs in glioblastoma Review

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology Research Paper

Folinic acid in colorectal cancer: esquire or fellow knight? Real-world results from a mono institutional, retrospective study Research Paper

Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells Research Paper

Advances in epidermal growth factor receptor specific immunotherapy: lessons to be learned from armed antibodies Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Correction: Downregulation of c-SRC kinase CSK promotes castration resistant prostate cancer and pinpoints a novel disease subclass Correction

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death Research Paper

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response Research Paper

Transformation-associated recombination (TAR) cloning and its applications for gene function; genome architecture and evolution; biotechnology and biomedicine Review

Targeting Ras with protein engineering Review

LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair Research Paper

Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival Research Paper

Deciphering miR-520c-3p as a probable target for immunometabolism in non-small cell lung cancer using systems biology approach Research Paper

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity Research Paper

Emerging approaches of wound healing in experimental models of high-grade oral mucositis induced by anticancer therapy Review

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Anti-aging: senolytics or gerostatics (unconventional view) Review

Role of microRNAs in glioblastoma Review

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology Research Paper

Folinic acid in colorectal cancer: esquire or fellow knight? Real-world results from a mono institutional, retrospective study Research Paper

Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells Research Paper

Advances in epidermal growth factor receptor specific immunotherapy: lessons to be learned from armed antibodies Review