The Oncosearch | Oncotarget

Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties Research Paper

Alan Halim, Nasreen Al-Qadi, Elizabeth Kenyon, Kayla N. Conner, Sujan Kumar Mondal, Zdravka Medarova, Anna Moore

Published Aug 17, 2024 · Vol. 15, No. 1 · pp. 591-606

Keywords: breast cancer, metastasis, stem-like cells, nanoparticle, miR-10b

Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status Research Paper

Jun Zhang, Lanlan Zhou, Shuai Zhao, Wafik S. El-Deiry

Published Jun 24, 2024 · Vol. 15, No. 1 · pp. 424-438

Keywords: TAS102, regorafenib, ERK1/2, angiogenesis, microvessel density

Inhibiting BRAF/EGFR/MEK suppresses cancer stemness and drug resistance of primary colorectal cancer cells Research Paper

Astha Lamichhane, Gary D. Luker, Seema Agarwal, Hossein Tavana

Published Sep 25, 2023 · Vol. 14, No. 1 · pp. 879-889

Keywords: drug resistance, cancer stem cells, patient-derived tumor model, colorectal cancer, combination treatment

Role of creatine shuttle in colorectal cancer cells Research Paper

Mayu Kita, Rina Fujiwara-Tani, Shingo Kishi, Shiori Mori, Hitoshi Ohmori, Chie Nakashima, Kei Goto, Takamitsu Sasaki, Kiyomu Fujii, Isao Kawahara, Ujjal Kumar Bhawal, Yi Luo, Hiroki Kuniyasu

Published May 12, 2023 · Vol. 14, No. 1 · pp. 485-501

Keywords: creatine kinase B, mitochondrial creatine kinase, ATP metabolism, phosphorylation signal, stemness

Targeting the Src N-terminal regulatory element in cancer Research Perspective

Betlem Mezquita, Marjorie Reyes-Farias, Miquel Pons

Published May 12, 2023 · Vol. 14, No. 1 · pp. 503-513

Keywords: Src family kinases, intrinsically disordered proteins, SNRE, cell-type selective drugs, drug resistance

HOXB9 mediates resistance to chemotherapy and patient outcomes through the TGFβ pathway in pancreatic cancer Research Paper

Naokazu Chiba, Shigeto Ochiai, Takahiro Gunji, Toshimichi Kobayashi, Toru Sano, Koichi Tomita, Shigeyuki Kawachi

Published May 11, 2022 · Vol. 13, No. 1 · pp. 747-754

Keywords: HOXB9, pancreatic cancer, epithelial mesenchymal transition, TGFβ

Suppressive GLI2 fragment enhances liver metastasis in colorectal cancer Research Paper

Ruiko Ogata, Shiori Mori, Hitoshi Ohmori, Shingo Kishi, Rina Fujiwara-Tani, Takamitsu Sasaki, Yukiko Nishiguchi, Chie Nakashima, Kei Goto, Isao Kawahara, Yi Luo, Hiroki Kuniyasu

Published Dec 23, 2021 · Vol. 13, No. 1 · pp. 122-135

Keywords: linoleic acid, stemness, GLI2, ubiquitination, colorectal cancer

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

Arvin Medhat, Alla Arzumanyan, Mark A. Feitelson

Published Sep 11, 2021 · Vol. 12, No. 24 · pp. 2421-2433

Keywords: chronic liver disease, hepatocellular carcinoma, HBx, functional cure, epigenetic

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Matthew Devall, Christopher H. Dampier, Stephen Eaton, Mourad W. Ali, Virginia Díez-Obrero, Ferran Moratalla-Navarro, Jennifer Bryant, Lucas T. Jennelle, Victor Moreno, Steven M. Powell, Ulrike Peters, Graham Casey

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1863-1877

Keywords: colon organoids, microsatellite instability, smoking, single-cell deconvolution, weighted gene co-expression network analysis

UBE2T: A new molecular regulator of cancer stemness in hepatocellular carcinoma Editorial

Rainbow Wing Hei Leung, Nicole Pui Yu Ho, Carmen Oi Ning Leung, Terence Kin Wah Lee

Published Jul 24, 2021 · Vol. 12, No. 17 · pp. 1727-1728

Keywords: beta-catenin, cancer stem cells, UBE2T, hepatocellular carcinoma

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Subarna Ghosh, Priyanka Dey Talukdar, Abhinandan Bhattacharjee, Sarbani Giri, Nitai Pada Bhattacharyya, Urmi Chatterji

Published Jul 2, 2021 · Vol. 12, No. 15 · pp. 1520-1539

Keywords: arecoline, tight junction, head and neck cancer, lncRNA-NEAT1, JunD

Multifaceted effect of chlorpromazine in cancer: implications for cancer treatment Review

Pareesa Kamgar-Dayhoff, Tinatin I. Brelidze

Published Jun 19, 2021 · Vol. 12, No. 14 · pp. 1406-1426

Keywords: chlorpromazine, repurposing

Controlling for cellular heterogeneity using single-cell deconvolution of gene expression reveals novel markers of colorectal tumors exhibiting microsatellite instability Research Paper

Matthew A.M. Devall, Graham Casey

Published Mar 30, 2021 · Vol. 12, No. 8 · pp. 767-782

Keywords: colorectal cancer, single-cell deconvolution, microsatellite instability, RNA-sequencing, enteroendocrine

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

Juyeon Ko, April N. Meyer, Martin Haas, Daniel J. Donoghue

Published Dec 23, 2020 · Vol. 12, No. 1 · pp. 22-36

Keywords: metastatic castrate-resistant prostate cancer, spheroid culture, tyrosine kinase inhibitor

Amalgamation of PI3K and EZH2 blockade synergistically regulates invasion and angiogenesis: combination therapy for glioblastoma multiforme Research Paper

Vishnu S. Mishra, Naveen Kumar, Masoom Raza, Seema Sehrawat

Published Dec 2, 2020 · Vol. 11, No. 51 · pp. 4754-4769

Keywords: precision neuroOncology, combination therapy, glioblastoma multiforme, pharmacological intervention, cytokine based proteomics

CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells Research Paper

Fatemeh Rajabi, Win-Yan Liu-Bordes, Marina Pinskaya, Foretek Dominika, Gueorgui Kratassiouk, Guillaume Pinna, Simona Nanni, Antonella Farsetti, Christian Gespach, Arturo Londoño-Vallejo, Irina Groisman

Published Nov 4, 2020 · Vol. 11, No. 45 · pp. 4155-4168

Keywords: miR-145-5p, TWIST1, CPEB1, EMT, prostate cancer

AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity Research Paper

Bhumika Wadhwa, Masroor Paddar, Sameer Khan, Sameer Mir, Philip A.Clarke, Anna M. Grabowska, Devanahalli G. Vijay, Fayaz Malik

Published Sep 8, 2020 · Vol. 11, No. 45 · pp. 4178-4194

Keywords: AKT isoform, CSCs, ABCG2, drug resistance, TNBCs

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

Matthew J. Kling, Nagendra K. Chaturvedi, Varun Kesherwani, Don W. Coulter, Timothy R. McGuire, J. Graham Sharp, Shantaram S. Joshi

Published Jul 30, 2020 · Vol. 11, No. 40 · pp. 3633-3645

Keywords: exosomes, hypoxia, Ewing’s sarcoma, stemness, miR-210

Correction: CFC1 is a cancer stemness-regulating factor in neuroblastoma Correction

Koji Chikaraishi, Hisanori Takenobu, Ryuichi P. Sugino, Kyosuke Mukae, Jesmin Akter, Masayuki Haruta, Masafumi Kurosumi, Takaho A. Endo, Haruhiko Koseki, Naoki Shimojo, Miki Ohira, Takehiko Kamijo

Published Jul 3, 2020

Diabetes mellitus is associated with liver metastasis of colorectal cancer through production of biglycan-rich cancer stroma Research Paper

Rina Fujiwara-Tani, Takamitsu Sasaki, Kiyomu Fujii, Yi Luo, Takuya Mori, Shingo Kishi, Shiori Mori, Sayako Matsushima-Otsuka, Yukiko Nishiguchi, Kei Goto, Isao Kawahara, Masuo Kondoh, Masayuki Sho, Hiroki Kuniyasu

Published Jun 30, 2020 · Vol. 11, No. 31 · pp. 2982-2994

Keywords: diabetes, liver metastasis, colorectal cancer, biglycan, mesenchymal stem cell

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Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties Research Paper

Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status Research Paper

Inhibiting BRAF/EGFR/MEK suppresses cancer stemness and drug resistance of primary colorectal cancer cells Research Paper

Role of creatine shuttle in colorectal cancer cells Research Paper

Targeting the Src N-terminal regulatory element in cancer Research Perspective

HOXB9 mediates resistance to chemotherapy and patient outcomes through the TGFβ pathway in pancreatic cancer Research Paper

Suppressive GLI2 fragment enhances liver metastasis in colorectal cancer Research Paper

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

UBE2T: A new molecular regulator of cancer stemness in hepatocellular carcinoma Editorial

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Multifaceted effect of chlorpromazine in cancer: implications for cancer treatment Review

Controlling for cellular heterogeneity using single-cell deconvolution of gene expression reveals novel markers of colorectal tumors exhibiting microsatellite instability Research Paper

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

Amalgamation of PI3K and EZH2 blockade synergistically regulates invasion and angiogenesis: combination therapy for glioblastoma multiforme Research Paper

CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells Research Paper

AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity Research Paper

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

Correction: CFC1 is a cancer stemness-regulating factor in neuroblastoma Correction

Diabetes mellitus is associated with liver metastasis of colorectal cancer through production of biglycan-rich cancer stroma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties Research Paper

Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status Research Paper

Inhibiting BRAF/EGFR/MEK suppresses cancer stemness and drug resistance of primary colorectal cancer cells Research Paper

Role of creatine shuttle in colorectal cancer cells Research Paper

Targeting the Src N-terminal regulatory element in cancer Research Perspective

HOXB9 mediates resistance to chemotherapy and patient outcomes through the TGFβ pathway in pancreatic cancer Research Paper

Suppressive GLI2 fragment enhances liver metastasis in colorectal cancer Research Paper

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

UBE2T: A new molecular regulator of cancer stemness in hepatocellular carcinoma Editorial

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Multifaceted effect of chlorpromazine in cancer: implications for cancer treatment Review

Controlling for cellular heterogeneity using single-cell deconvolution of gene expression reveals novel markers of colorectal tumors exhibiting microsatellite instability Research Paper

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

Amalgamation of PI3K and EZH2 blockade synergistically regulates invasion and angiogenesis: combination therapy for glioblastoma multiforme Research Paper

CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells Research Paper

AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity Research Paper

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

Correction: CFC1 is a cancer stemness-regulating factor in neuroblastoma Correction

Diabetes mellitus is associated with liver metastasis of colorectal cancer through production of biglycan-rich cancer stroma Research Paper