The Oncosearch | Oncotarget

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Joel Ohana, Uziel Sandler, Benjamin A. Weinberg, Stephen Liu, Yoram Devary

Published Dec 19, 2025 · Vol. 16, No. 1 · pp. 848-857

Keywords: mutant KRAS, Nerofe, ST2 Receptor, tumor immune microenvironment, nuclear immunomodulation

Worldwide Innovative Network (WIN) Consortium in Personalized Cancer Medicine: Bringing next-generation precision oncology to patients Precision Oncology

Wafik S. El-Deiry, Catherine Bresson, Fanny Wunder, Benedito A. Carneiro, Don S. Dizon, Jeremy L. Warner, Stephanie L. Graff, Christopher G. Azzoli, Eric T. Wong, Liang Cheng, Sendurai A. Mani, Howard P. Safran, Casey Williams, Tobias Meissner, Benjamin Solomon, Eitan Rubin, Angel Porgador, Guy Berchem, Pierre Saintigny, Amir Onn, Jair Bar, Raanan Berger, Manon Gantenbein, Zhen Chen, Cristiano de Pádua Souza, Rui Manuel Vieira Reis, Marina Sekacheva, Andrés Cervantes, William L. Dahut, Christina M. Annunziata, Kerri Gober, Khaled M. Musallam, Humaid O. Al-Shamsi, Ibrahim Abu-Gheida, Ramon Salazar, Sewanti Limaye, Adel T. Aref, Roger R. Reddel, Mohammed Ussama Al Homsi, Abdul Rouf, Said Dermime, Jassim Al Suwaidi, Catalin Vlad, Rares Buiga, Amal Al Omari, Hikmat Abdel-Razeq, Luis F. Oñate-Ocaña, Finn Cilius Nielsen, Leah Graham, Jens Rueter, Anthony M. Joshua, Eugenia Girda, Steven Libutti, Gregory Riedlinger, Mohammed E. Salem, Carol J. Farhangfar, Ruben A. Mesa, Bishoy M. Faltas, Olivier Elemento, C.S. Pramesh, Manju Sengar, Satoru Aoyama, Sadakatsu Ikeda, Ioana Berindan-Neagoe, Himabindu Gaddipati, Mandar Kulkarni, Elisabeth Auzias, Maria Gerogianni, Nicolas Wolikow, Simon Istolainen, Pessie Schlafrig, Naftali Z. Frankel, Amanda R. Ferraro, Jim Palma, Alejandro Piris Gimenez, Alberto Hernando-Calvo, Enriqueta Felip, Apostolia M. Tsimberidou, Roy S. Herbst, Josep Tabernero, Richard L. Schilsky, Jia Liu, Yves Lussier, Jacques Raynaud, Gerald Batist, Shai Magidi, Razelle Kurzrock

Published Mar 12, 2025 · Vol. 16, No. 1 · pp. 140-162

Keywords: precision oncology, N-of-1 basket trials, AI algorithms, digital pathology, drug access

Addendum: Effectiveness of radiotherapy for local control in T3N0 rectal cancer managed with total mesorectal excision: a meta-analysis Addendum

Michael Jonathan Kucharczyk, Andrew Bang, Michael C. Tjong, Stefania Papatheodorou, Jesus C. Fabregas

Published Jul 26, 2023 · Vol. 14, No. 1 · pp. 778-778

Effectiveness of radiotherapy for local control in T3N0 rectal cancer managed with total mesorectal excision: a meta-analysis Research Paper

Michael Jonathan Kucharczyk, Andrew Bang, Michael C. Tjong, Stefania Papatheodorou, Jesus C. Fabregas

Published Sep 30, 2022 · Vol. 13, No. 1 · pp. 1109-1119

Keywords: radiotherapy, meta-analysis, systematic review, rectal cancer, total mesorectal excision

THIS IS A TEST PAPER - NOT FOR PRODUCTION Research Paper

Marina Baretti, Qingfeng Zhu, Wei Fu, Jeffrey Meyer, Hao Wang, Robert A. Anders, Nilofer S. Azad

Published Jul 13, 2022

Keywords: programmed death ligand 1, tumor-infiltrating lymphocytes, immune checkpoints, colorectal cancer, neoadjuvant chemoradiotherapy

Chemoradiation-induced alteration of programmed death-ligand 1, CD8+ tumor-infiltrating lymphocytes and mucin expression in rectal cancer Research Paper

Marina Baretti, Qingfeng Zhu, Wei Fu, Jeffrey Meyer, Hao Wang, Robert A. Anders, Nilofer S. Azad

Published Jul 6, 2022 · Vol. 13, No. 1 · pp. 907-917

Keywords: programmed death ligand 1, tumor-infiltrating lymphocytes, immune checkpoints, colorectal cancer, neoadjuvant chemoradiotherapy

The “Immunoscore” in rectal cancer: could we search quality beyond quantity of life? Research Perspective

Amos Kirilovsky, Carine El Sissy, Guy Zeitoun, Florence Marliot, Nacilla Haicheur, Christine Lagorce-Pagès, Julien Taieb, Mehdi Karoui, Petra Custers, Edina Dizdarevic, Soledad Iseas, Torben Frøstrup Hansen, Lars Henrik Jensen, Geerard Beets, Jean Pierre Gérard, Mireia Castillo-Martin, Nuno Figueiredo, Angelita Habr-Gama, Rodrigo Perez, Jérôme Galon, Franck Pagès

Published Oct 16, 2021 · Vol. 13, No. 1 · pp. 18-31

Keywords: rectal cancer, immunoscore, watch and wait, prognosis, radiochemotherapy

The impact of neoadjuvant concurrent chemoradiation on exosomal markers (CD63 and CD9) expression and their prognostic significance in patients with rectal adenocarcinoma Research Paper

Moh’d Khushman, Pranitha Prodduturvar, Wadad Mneimneh, Valeria Dal Zotto, Shalla Akbar, Leander Grimm, Paul Rider, John Hunter, Omar Alkharabsheh, Girijesh Kumar Patel, Jesus C. Fabregas, Ajay P. Singh

Published Jun 30, 2021 · Vol. 12, No. 15 · pp. 1490-1498

Keywords: exosomes, exosomal markers, CD63, CD9, neoadjuvant chemoradiation

Cross-talks in colon cancer between RAGE/AGEs axis and inflammation/immunotherapy Review

Annachiara Mollace, Maria Laura Coluccio, Giuseppe Donato, Vincenzo Mollace, Natalia Malara

Published Jun 9, 2021 · Vol. 12, No. 13 · pp. 1281-1295

Keywords: RAGE, AGEs, colon cancer, microenvironment, Warburg effect

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

Austin R. Dosch, Walid K. Chatila, Yuguang Ban, Anna Bianchi, Nilesh U. Deshpande, Iago De Castro Silva, Nipun B. Merchant, Jashodeep Datta

Published Jun 1, 2021 · Vol. 12, No. 20 · pp. 2104-2110

Keywords: Ras-p53 cooperativity, Ras, TP53, immune, gastrointestinal cancer

The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy Research Paper

H.M.C. Shantha Kumara, Elie Sutton, Otavia L. Caballero, Tao Su, Xiaohong Yan, Aqeel Ahmed, Sonali A.C. Herath, Vesna Cekic, Linda Njoh, Daniel D. Kirchoff, Richard L. Whelan

Published Feb 9, 2021 · Vol. 12, No. 5 · pp. 412-421

Keywords: cancer testis antigens, colorectal cancer, CABYR a/b, c

Correction: Preoperative chemoradiotherapy for rectal cancer: the sensitizer role of the association between miR-375 and c-Myc Correction

Raquel Conde-Muiño, Carlos Cano, Victoria Sánchez-Martín, Antonio Herrera-Merchan, Ana Comino, Pedro P. Medina, Pablo Palma, Marta Cuadros

Published Mar 24, 2020 · Vol. 11, No. 13 · pp. 1202-1202

Age-dependent response to multimodal therapy for stage II-III rectal cancer Editorial

Daniel Delitto, Tyler J. Loftus, Atif Iqbal

Published Jul 6, 2019 · Vol. 10, No. 45 · pp. 4615-4615

Keywords: young, rectal cancer, survival, age

Multidisciplinary palliation for unresectable recurrent rectal cancer: hypoxic pelvic perfusion with mitomycin C and oxaliplatin in patients progressing after systemic chemotherapy and radiotherapy, a retrospective cohort study Research Paper

Stefano Guadagni, Giammaria Fiorentini, Andrea Mambrini, Francesco Masedu, Marco Valenti, Andrew Reay Mackay, Donatella Sarti, Enrico Ricevuto, Marco Clementi, Marco Catarci, Gianni Lazzarin, Gemma Bruera

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3840-3851

Keywords: hypoxic pelvic perfusion with mitomycin C and oxaliplatin, unresectable recurrent rectal cancer, retrospective cohort study

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Review

Stefano Guadagni, Giammaria Fiorentini, Andrea Mambrini, Francesco Masedu, Marco Valenti, Andrew Reay Mackay, Donatella Sarti, Enrico Ricevuto, Marco Clementi, Marco Catarci, Gianni Lazzarin, Gemma Bruera

Published May 14, 2019

Keywords: hypoxic pelvic perfusion with mitomycin C and oxaliplatin, unresectable recurrent rectal cancer, retrospective cohort study

Organ preservation for T2-T3 rectal cancer: opportunistic or planned strategy Editorial

Jéan-Pierre Gérard, Nicolas Barbet, Karen Benezery

Published Apr 30, 2019 · Vol. 10, No. 37 · pp. 3431-3432

Keywords: rectal cancer, conservative treatment, contact X-ray brachytherapy, clinical complete response, non operative modality

Phospho-ERK levels as predictors for chemotherapy of rectal carcinoma Research Paper

Susanne Holck, Louise Laurberg Klarskov, Lars-Inge Larsson

Published Mar 1, 2019 · Vol. 10, No. 18 · pp. 1745-1755

Correction: The combination of early treatment response and ypT stage is a novel metric to stage rectal cancer patients treated with neoadjuvant chemoradiotherapy Correction

Jian Cui, Lin Yang, Lei Guo, Yongfu Shao, Dongfeng Tan, Ni Li, Haizeng Zhang

Published Feb 19, 2019 · Vol. 10, No. 15 · pp. 1539-1539

Pathologic stage dictates survival after neoadjuvant radiation for rectal cancer Editorial

Daniel Delitto, Tyler J. Loftus, Atif Iqbal

Published Oct 16, 2018 · Vol. 9, No. 84 · pp. 35474-35475

Induction chemotherapy followed by neoadjuvant chemoradiotherapy and surgery in locally advanced rectal cancer: preliminary results of a phase II study Research Paper

Francesca De Felice, Giancarlo Dâ€™Ambrosio, Daniela Musio, Franco Iafrate, Ilaria Benevento, Marco Marzo, Marialaura Mancini, Federica Urbano, Marcella Iannitti, Francesco Marampon, Nadia Bulzonetti, Enrico Cortesi, Vincenzo Tombolini

Published Sep 14, 2018 · Vol. 9, No. 72 · pp. 33702-33709

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Worldwide Innovative Network (WIN) Consortium in Personalized Cancer Medicine: Bringing next-generation precision oncology to patients Precision Oncology

Addendum: Effectiveness of radiotherapy for local control in T3N0 rectal cancer managed with total mesorectal excision: a meta-analysis Addendum

Effectiveness of radiotherapy for local control in T3N0 rectal cancer managed with total mesorectal excision: a meta-analysis Research Paper

THIS IS A TEST PAPER - NOT FOR PRODUCTION Research Paper

Chemoradiation-induced alteration of programmed death-ligand 1, CD8+ tumor-infiltrating lymphocytes and mucin expression in rectal cancer Research Paper

The “Immunoscore” in rectal cancer: could we search quality beyond quantity of life? Research Perspective

The impact of neoadjuvant concurrent chemoradiation on exosomal markers (CD63 and CD9) expression and their prognostic significance in patients with rectal adenocarcinoma Research Paper

Cross-talks in colon cancer between RAGE/AGEs axis and inflammation/immunotherapy Review

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy Research Paper

Correction: Preoperative chemoradiotherapy for rectal cancer: the sensitizer role of the association between miR-375 and c-Myc Correction

Age-dependent response to multimodal therapy for stage II-III rectal cancer Editorial

Multidisciplinary palliation for unresectable recurrent rectal cancer: hypoxic pelvic perfusion with mitomycin C and oxaliplatin in patients progressing after systemic chemotherapy and radiotherapy, a retrospective cohort study Research Paper

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Review

Organ preservation for T2-T3 rectal cancer: opportunistic or planned strategy Editorial

Phospho-ERK levels as predictors for chemotherapy of rectal carcinoma Research Paper

Correction: The combination of early treatment response and ypT stage is a novel metric to stage rectal cancer patients treated with neoadjuvant chemoradiotherapy Correction

Pathologic stage dictates survival after neoadjuvant radiation for rectal cancer Editorial

Induction chemotherapy followed by neoadjuvant chemoradiotherapy and surgery in locally advanced rectal cancer: preliminary results of a phase II study Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Worldwide Innovative Network (WIN) Consortium in Personalized Cancer Medicine: Bringing next-generation precision oncology to patients Precision Oncology

Addendum: Effectiveness of radiotherapy for local control in T3N0 rectal cancer managed with total mesorectal excision: a meta-analysis Addendum

Effectiveness of radiotherapy for local control in T3N0 rectal cancer managed with total mesorectal excision: a meta-analysis Research Paper

THIS IS A TEST PAPER - NOT FOR PRODUCTION Research Paper

Chemoradiation-induced alteration of programmed death-ligand 1, CD8+ tumor-infiltrating lymphocytes and mucin expression in rectal cancer Research Paper

The “Immunoscore” in rectal cancer: could we search quality beyond quantity of life? Research Perspective

The impact of neoadjuvant concurrent chemoradiation on exosomal markers (CD63 and CD9) expression and their prognostic significance in patients with rectal adenocarcinoma Research Paper

Cross-talks in colon cancer between RAGE/AGEs axis and inflammation/immunotherapy Review

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy Research Paper

Correction: Preoperative chemoradiotherapy for rectal cancer: the sensitizer role of the association between miR-375 and c-Myc Correction

Age-dependent response to multimodal therapy for stage II-III rectal cancer Editorial

Multidisciplinary palliation for unresectable recurrent rectal cancer: hypoxic pelvic perfusion with mitomycin C and oxaliplatin in patients progressing after systemic chemotherapy and radiotherapy, a retrospective cohort study Research Paper

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Review

Organ preservation for T2-T3 rectal cancer: opportunistic or planned strategy Editorial

Phospho-ERK levels as predictors for chemotherapy of rectal carcinoma Research Paper

Correction: The combination of early treatment response and ypT stage is a novel metric to stage rectal cancer patients treated with neoadjuvant chemoradiotherapy Correction

Pathologic stage dictates survival after neoadjuvant radiation for rectal cancer Editorial

Induction chemotherapy followed by neoadjuvant chemoradiotherapy and surgery in locally advanced rectal cancer: preliminary results of a phase II study Research Paper