The Oncosearch | Oncotarget

CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer Research Paper

Allison Makovec, John T. Phoenix, Hannah E. Bergom, Ella Boytim, Ava P. Gustafson, Aiden Deacon, Sydney Tape, Atef Ali, Megan Ludwig, Samuel P. Pitzen, David Moline, Camden Richter, Hudson Longie, Mei-Chi Su, Sampreeti Jena, Pornlada Likasitwatanakul, Justin M. Drake, R. Stephanie Huang, William C. Hahn, Jonathan P. Rennhack, Scott M. Dehm, Steven Kregel, Emmanuel S. Antonarakis, Justin Hwang

Published Mar 30, 2026 · Vol. 17, No. 1 · pp. 59-73

Keywords: prostate cancer, CREB5, basal-like, stem cell-like, AP-1 transcription factors

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Joel Ohana, Uziel Sandler, Benjamin A. Weinberg, Stephen Liu, Yoram Devary

Published Dec 19, 2025 · Vol. 16, No. 1 · pp. 848-857

Keywords: mutant KRAS, Nerofe, ST2 Receptor, tumor immune microenvironment, nuclear immunomodulation

Retraction: Netrin-1 promotes gastric cancer cell proliferation and invasion via the receptor neogenin through PI3K/AKT signaling pathway Retraction

Kai Yin, Linjun Wang, Xuan Zhang, Zhongyuan He, Yiwen Xia, Jianghao Xu, Song Wei, Bowen Li, Zheng Li, Guangli Sun, Qing Li, Hao Xu, Zekuan Xu

Published Dec 17, 2025 · Vol. 16, No. 1 · pp. 878-878

Widespread folate receptor expression in pediatric and adolescent solid tumors - opportunity for intraoperative visualization with the novel fluorescent agent pafolacianine Research Paper

Ashley C. Dodd, Nitin R. Wadhwani, Alison Lehane, Rom Brown, Kyle L. MacQuarrie, Seth D. Goldstein, Timothy B. Lautz

Published Oct 13, 2025 · Vol. 16, No. 1 · pp. 759-767

Keywords: folate receptor, fluorescent-guided surgery, pediatric tumors, pafolacianine, RNA sequencing

Treatment of glioblastoma with tumor-specific amplitude-modulated radiofrequency electromagnetic fields Research Paper

Hugo Jimenez, Denise Gibo, Sambad Sharma, Michael Pennison, Lance D. Miller, Minghui Wang, Kimberly Sheffield, Liyue Zhang, Allan Johansen, Preeya Achari, Callum Mcgrath, Sean Lester, Jason Tang, Kojo Agyemang, Annette Johnson, Christopher T. Whitlow, Michael Chan, Kounosuke Watabe, Ralph D’Agostino Jr., Janaka Liyanage, Asfar Azmi, Geoffrey Barger, Alexandre Barbault, Glenn J. Lesser, Waldemar Debinski, Boris C. Pasche

Published Oct 2, 2025 · Vol. 16, No. 1 · pp. 741-757

Keywords: amplitude-modulated radiofrequency electromagnetic fields, glioblastoma, TheraBionic, CACNA1H, Ca_v3.2

PCAIs stimulate MAPK, PI3K/AKT pathways and ROS-Mediated apoptosis in aromatase inhibitor-resistant breast cancer cells while disrupting actin filaments and focal adhesion Research Paper

Jassy Mary S. Lazarte, Kweku Ofosu-Asante, Syreeta L. Tilghman, Nazarius S. Lamango

Published Jul 22, 2025 · Vol. 16, No. 1 · pp. 621-641

Keywords: PCAIs, ROS, MAPK, PI3K/AKT, LTLT-Ca cells

Dissecting the functional differences and clinical features of R-spondin family members in metastatic prostate cancer Research Paper

Aiden Deacon, Ava Gustafson, Allison Makovec, Ella Boytim, Gabriella von Dohlen, David Moline, Elin Kairies, Sam Kellen, Khalid Ishani, Megan L. Ludwig, Emily John, Alexis Anike, Hai Dang Nguyen, Scott M. Dehm, Justin M. Drake, Emmanuel S. Antonarakis, Justin Hwang

Published Jul 19, 2025 · Vol. 16, No. 1 · pp. 606-620

Keywords: RSPO2, prostate cancer, Wnt signaling, genomics, therapeutics

Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms Review

Shreya Shyamsunder, Zhixin Lu, Vinita Takiar, Susan E. Waltz

Published Jun 16, 2025 · Vol. 16, No. 1 · pp. 508-530

Keywords: EGFR, RTKs, breast cancer, head and neck cancer, resistance mechanisms

Retraction: Androgen receptor promotes gastric cancer cell migration and invasion via AKT-phosphorylation dependent upregulation of matrix metalloproteinase 9 Retraction

Bao-gui Zhang, Tao Du, Ming-de Zang, Qing Chang, Zhi-yuan Fan, Jian-fang Li, Bei-qin Yu, Li-ping Su, Chen Li, Chao Yan, Qin-long Gu, Zheng-gang Zhu, Min Yan, Bingya Liu

Published May 29, 2025 · Vol. 16, No. 1 · pp. 410-410

Durable complete response in leptomeningeal disease of EGFR mutated non-small cell lung cancer to amivantamab, an EGFR-MET receptor bispecific antibody, after progressing on osimertinib Research Paper

Jinah Kim, Liam Il-Young Chung, Horyun Choi, Yoonhee Choi, Maria Jose Aguilera Chuchuca, Youjin Oh, Young Kwang Chae

Published May 21, 2025 · Vol. 16, No. 1 · pp. 411-418

Keywords: amivantamab, monotherapy, rare EGFR mutation, NSCLC, leptomeningeal disease

Targeting PCNA/AR interaction inhibits AR-mediated signaling in castration resistant prostate cancer cells Research Paper

Shan Lu, Zhongyun Dong

Published May 8, 2025 · Vol. 16, No. 1 · pp. 383-395

Keywords: PCNA, androgen receptor, PCNA inhibitors, AR splicing variants, CRPC

Correction: Small molecule inhibition of Axl receptor tyrosine kinase potently suppresses multiple malignant properties of glioma cells Correction

Mikaella Vouri, Qian An, Matthew Birt, Geoffrey J. Pilkington, Sassan Hafizi

Published Apr 4, 2025 · Vol. 16, No. 1 · pp. 260-261

FGR Src family kinase causes signaling and phenotypic shift mimicking retinoic acid-induced differentiation of leukemic cells Research Paper

Noor Kazim, Wang Peng, Jianbo Yue, Andrew Yen

Published Mar 14, 2025 · Vol. 16, No. 1 · pp. 202-218

Keywords: cancer biology and cell cycle regulation, retinoic acid(RA), FGR Src-family-kinase, cancer differentiation-therapy, leukemia

Signaling pathway dysregulation in breast cancer Review

Dinara Ryspayeva, Attila A. Seyhan, William J. MacDonald, Connor Purcell, Tyler J. Roady, Maryam Ghandali, Nataliia Verovkina, Wafik S. El-Deiry, Martin S. Taylor, Stephanie L. Graff

Published Mar 7, 2025 · Vol. 16, No. 1 · pp. 168-201

Keywords: breast cancer, oncogenic pathways, signal dysregulation in cancer, therapeutic approaches, clinical trials

Addendum: Assessment of cholecystokinin 2 receptor (CCK2R) in neoplastic tissue Addendum

Jyoti Roy, Karson S. Putt, Domenico Coppola, Marino E. Leon, Farah K. Khalil, Barbara A. Centeno, Noel Clark, Valerie E. Stark, David L. Morse, Philip S. Low

Published Mar 5, 2025 · Vol. 16, No. 1 · pp. 132-132

Correction: Catalytic inhibitors of DNA topoisomerase II suppress the androgen receptor signaling and prostate cancer progression Correction

Haolong Li, Ning Xie, Martin E. Gleave, Xuesen Dong

Published Feb 12, 2025 · Vol. 16, No. 1 · pp. 63-64

Could Panitumumab with very low dose Capecitabine be an option as a maintenance regimen Research Paper

Doaa A. Gamal, Aiat Morsy, Mervat Omar

Published Jan 29, 2025 · Vol. 16, No. 1 · pp. 67-78

Keywords: Panitumumab, maintenance, colorectal cancer, Capecitabine

Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 rearranged non-small cell lung cancer: A case report Case Report

Jenny L. Wu, Wade T. Iams

Published Jan 16, 2025 · Vol. 16, No. 1 · pp. 39-42

Keywords: ROS1 rearrangement, RET rearrangement, non-small cell lung cancer, targeted therapy, case report

Evolving concepts in HER2-low breast cancer: Genomic insights, definitions, and treatment paradigms Review

Whitney L. Hensing, Emily L. Podany, James J. Sears, Shaili Tapiavala, Andrew A. Davis

Published Jan 9, 2025 · Vol. 16, No. 1 · pp. 11-27

Keywords: breast cancer, HER2-low, genomics

Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells Research Paper

Steven A. Greenberg

Published Jan 7, 2025 · Vol. 16, No. 1 · pp. 1-8

Keywords: immunotherapy, KLRG1

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CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer Research Paper

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Retraction: Netrin-1 promotes gastric cancer cell proliferation and invasion via the receptor neogenin through PI3K/AKT signaling pathway Retraction

Widespread folate receptor expression in pediatric and adolescent solid tumors - opportunity for intraoperative visualization with the novel fluorescent agent pafolacianine Research Paper

Treatment of glioblastoma with tumor-specific amplitude-modulated radiofrequency electromagnetic fields Research Paper

PCAIs stimulate MAPK, PI3K/AKT pathways and ROS-Mediated apoptosis in aromatase inhibitor-resistant breast cancer cells while disrupting actin filaments and focal adhesion Research Paper

Dissecting the functional differences and clinical features of R-spondin family members in metastatic prostate cancer Research Paper

Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms Review

Retraction: Androgen receptor promotes gastric cancer cell migration and invasion via AKT-phosphorylation dependent upregulation of matrix metalloproteinase 9 Retraction

Durable complete response in leptomeningeal disease of EGFR mutated non-small cell lung cancer to amivantamab, an EGFR-MET receptor bispecific antibody, after progressing on osimertinib Research Paper

Targeting PCNA/AR interaction inhibits AR-mediated signaling in castration resistant prostate cancer cells Research Paper

Correction: Small molecule inhibition of Axl receptor tyrosine kinase potently suppresses multiple malignant properties of glioma cells Correction

FGR Src family kinase causes signaling and phenotypic shift mimicking retinoic acid-induced differentiation of leukemic cells Research Paper

Signaling pathway dysregulation in breast cancer Review

Addendum: Assessment of cholecystokinin 2 receptor (CCK2R) in neoplastic tissue Addendum

Correction: Catalytic inhibitors of DNA topoisomerase II suppress the androgen receptor signaling and prostate cancer progression Correction

Could Panitumumab with very low dose Capecitabine be an option as a maintenance regimen Research Paper

Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 rearranged non-small cell lung cancer: A case report Case Report

Evolving concepts in HER2-low breast cancer: Genomic insights, definitions, and treatment paradigms Review

Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer Research Paper

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Retraction: Netrin-1 promotes gastric cancer cell proliferation and invasion via the receptor neogenin through PI3K/AKT signaling pathway Retraction

Widespread folate receptor expression in pediatric and adolescent solid tumors - opportunity for intraoperative visualization with the novel fluorescent agent pafolacianine Research Paper

Treatment of glioblastoma with tumor-specific amplitude-modulated radiofrequency electromagnetic fields Research Paper

PCAIs stimulate MAPK, PI3K/AKT pathways and ROS-Mediated apoptosis in aromatase inhibitor-resistant breast cancer cells while disrupting actin filaments and focal adhesion Research Paper

Dissecting the functional differences and clinical features of R-spondin family members in metastatic prostate cancer Research Paper

Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms Review

Retraction: Androgen receptor promotes gastric cancer cell migration and invasion via AKT-phosphorylation dependent upregulation of matrix metalloproteinase 9 Retraction

Durable complete response in leptomeningeal disease of EGFR mutated non-small cell lung cancer to amivantamab, an EGFR-MET receptor bispecific antibody, after progressing on osimertinib Research Paper

Targeting PCNA/AR interaction inhibits AR-mediated signaling in castration resistant prostate cancer cells Research Paper

Correction: Small molecule inhibition of Axl receptor tyrosine kinase potently suppresses multiple malignant properties of glioma cells Correction

FGR Src family kinase causes signaling and phenotypic shift mimicking retinoic acid-induced differentiation of leukemic cells Research Paper

Signaling pathway dysregulation in breast cancer Review

Addendum: Assessment of cholecystokinin 2 receptor (CCK2R) in neoplastic tissue Addendum

Correction: Catalytic inhibitors of DNA topoisomerase II suppress the androgen receptor signaling and prostate cancer progression Correction

Could Panitumumab with very low dose Capecitabine be an option as a maintenance regimen Research Paper

Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 rearranged non-small cell lung cancer: A case report Case Report

Evolving concepts in HER2-low breast cancer: Genomic insights, definitions, and treatment paradigms Review

Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells Research Paper