The Oncosearch | Oncotarget

Retraction: LncRNA CHRFinduced miR-489 loss promotes metastasis of colorectal cancer via TWIST1/EMT signaling pathway Retraction

Youmao Tao, Tao Han, Tao Zhang, Chong Ma, Caixia Sun

Published Apr 24, 2026 · Vol. 17, No. 1 · pp. 197-198

Retraction: Loss of FOXN3 in colon cancer activates beta-catenin/TCF signaling and promotes the growth and migration of cancer cells Retraction

Yuedi Dai, Meixing Wang, Haixia Wu, Mi Xiao, Houbao Liu, Dexiang Zhang

Published Apr 17, 2026 · Vol. 17, No. 1 · pp. 184-184

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Joel Ohana, Uziel Sandler, Benjamin A. Weinberg, Stephen Liu, Yoram Devary

Published Dec 19, 2025 · Vol. 16, No. 1 · pp. 848-857

Keywords: mutant KRAS, Nerofe, ST2 Receptor, tumor immune microenvironment, nuclear immunomodulation

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma Research Paper

Jacob Haagsma, Yudith Ramos Valdes, Xuejin Ou, Rasheduzzaman Rashu, S.M. Mansour Haeryfar, Jim Petrik, Trevor G. Shepherd

Published Sep 16, 2025 · Vol. 16, No. 1 · pp. 697-718

Keywords: high-grade serous ovarian carcinoma, orthotopic models, inflammation, microenvironment

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

Kristen Kwong, Yue Pan, Jacqueline Morales, Matthew Watson, David V. Allegakoen, Alex G. Lee, Trever G. Bivona, Peter Wipf, Christopher J. Guerriero, Jeffrey L. Brodsky, Amit J. Sabnis

Published Aug 23, 2025 · Vol. 16, No. 1 · pp. 681-696

Keywords: protein homeostasis, rhabdomyosarcoma, unfolded protein response, preclinical therapeutics, p97

Clinical and analytical validation of MI Cancer Seek^®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay Research Paper

Valeriy Domenyuk, Kasey Benson, Peggy Carter, Daniel Magee, Jian Zhang, Nitin Bhardwaj, Hongseok Tae, James Wacker, Foram Rathi, Siobhan Miick, Aastha Kohli, Joshua Carroll, Lori Cuyugan, Evelyn Perez, Wayeesha Zhang, John Collins, Patrick Kennedy, Jeremy Ellis, Adam Stark, Andrey Loskutov, Brittany Cuttone, Blake Taylor, Rebecca Feldman, Jeff Swenson, David Bryant, Robert Hahn-Lowry, Raunaq Kaushal, Jennifer R. Ribeiro, Jim Abraham, Milan Radovich, George W. Sledge, Matthew Oberley, David Spetzler

Published Aug 6, 2025 · Vol. 16, No. 1 · pp. 642-659

Keywords: companion diagnostic, molecular profiling, solid tumors, precision oncology, next-generation sequencing

Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms Review

Shreya Shyamsunder, Zhixin Lu, Vinita Takiar, Susan E. Waltz

Published Jun 16, 2025 · Vol. 16, No. 1 · pp. 508-530

Keywords: EGFR, RTKs, breast cancer, head and neck cancer, resistance mechanisms

Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors Review

Helen Qian, Heba Ali, Vivekanudeep Karri, Justin T. Low, David M. Ashley, Amy B. Heimberger, Lucy A. Godley, Adam M. Sonabend, Crismita Dmello

Published Jun 5, 2025 · Vol. 16, No. 1 · pp. 445-453

Keywords: CHEK2, immune checkpoint inhibitors, immunomodulation

Cigarette smoke and decreased DNA repair by Xeroderma Pigmentosum Group C use a double hit mechanism for epithelial cell lung carcinogenesis Research Paper

Nawar Al Nasrallah, Bowa Lee, Benjamin M. Wiese, Marie N. Karam, Elizabeth A. Mickler, Huaxin Zhou, Nicki Paolelli, Robert S. Stearman, Mark W. Geraci, Catherine R. Sears

Published May 9, 2025 · Vol. 16, No. 1 · pp. 396-409

Keywords: DNA repair, DNA damage, lung adenocarcinoma, squamous cell carcinoma, Xeroderma Pigmentosum Group C (XPC)

Signaling pathway dysregulation in breast cancer Review

Dinara Ryspayeva, Attila A. Seyhan, William J. MacDonald, Connor Purcell, Tyler J. Roady, Maryam Ghandali, Nataliia Verovkina, Wafik S. El-Deiry, Martin S. Taylor, Stephanie L. Graff

Published Mar 7, 2025 · Vol. 16, No. 1 · pp. 168-201

Keywords: breast cancer, oncogenic pathways, signal dysregulation in cancer, therapeutic approaches, clinical trials

Robust p53 phenotypes and prospective downstream targets in telomerase-immortalized human cells Research Paper

Jessica J. Miciak, Lucy Petrova, Rhythm Sajwan, Aditya Pandya, Mikayla Deckard, Andrew J. Munoz, Fred Bunz

Published Feb 6, 2025 · Vol. 16, No. 1 · pp. 79-100

Keywords: p53, ionizing radiation, immortalized cells, ALDH3A1, NECTIN4

Leukopenia, weight loss and oral mucositis induced by 5-Fluorouracil in hamsters’ model: A regenerative approach using electrospun poly(Lactic-co-Glycolic Acid) membrane Research Paper

Ana Chor, Hélio dos Santos Dutra, Marcos Lopes Dias, Raquel Pires Gonçalves, Alexandre Malta Rossi, Christina Maeda Takiya, Marcos Farina

Published Jan 22, 2025 · Vol. 16, No. 1 · pp. 103-117

Keywords: leukopenia, weight loss, oral mucositis, PLGA dressing, regeneration

Molecular chaperones: Guardians of tumor suppressor stability and function Review

Jennifer A. Heritz, Sarah J. Backe,, Mehdi Mollapour

Published Sep 21, 2024 · Vol. 15, No. 1 · pp. 679-696

Keywords: molecular chaperone, tumor suppressor, renal cell carcinoma, Birt-Hogg-Dubé (BHD) syndrome, TSC syndrome

Linking FOXM1 and PD-L1 to CDK4/6-MEK targeted therapy resistance in malignant peripheral nerve sheath tumors Mini-Review

Joshua J. Lingo, Ellen Voigt, Dawn E. Quelle

Published Sep 19, 2024 · Vol. 15, No. 1 · pp. 638-643

Keywords: MPNST, FOXM1, PD-L1, CDK4/6-MEK targeting, therapy resistance

UBA1 dysfunction in VEXAS and cancer Research Perspective

Maki Sakuma, Torsten Haferlach, Wencke Walter

Published Aug 27, 2024 · Vol. 15, No. 1 · pp. 644-658

Keywords: VEXAS, MDS, clonal cytopenia, ubiquitin, inflammation

Deep learning-based whole-body PSMA PET/CT attenuation correction utilizing Pix-2-Pix GAN Research Paper

Kevin C. Ma, Esther Mena, Liza Lindenberg, Nathan S. Lay, Phillip Eclarinal, Deborah E. Citrin, Peter A. Pinto, Bradford J. Wood, William L. Dahut, James L. Gulley, Ravi A. Madan, Peter L. Choyke, Ismail Baris Turkbey, Stephanie A. Harmon

Published May 2, 2024 · Vol. 15, No. 1 · pp. 288-300

Keywords: deep learning, PSMA PET, attenuation correction

Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples Research Paper

Chongtham Sovachandra Singh, Nabamita Boruah, Atanu Banerjee, Sillarine Kurkalang, Pooja Swargiary, Hughbert Dakhar, Anupam Chatterjee

Published Jan 11, 2024 · Vol. 15, No. 1 · pp. 76-89

Keywords: Mad2 gene, histone methylation, histone acetylation, Rb-phosphorylation, esophageal cancer

Addendum: Genomic landscape of metastatic breast cancer (MBC) patients with methylthioadenosine phosphorylase (MTAP) loss Addendum

Maroun Bou Zerdan, Prashanth Ashok Kumar, Elio Haroun, Nimisha Srivastava, Jeffrey Ross, Abirami Sivapiragasam

Published Jul 14, 2023 · Vol. 14, No. 1 · pp. 747-747

Targeting H3K27me3 loss in pediatric brain tumors - a perspective on epigenetically guided cancer therapy Editorial

Michael Goldstein

Published May 5, 2023 · Vol. 14, No. 1 · pp. 444-447

Keywords: epigenetics, brain tumor, EZH2, H3K27me3, radiation therapy

Using cancer proteomics data to identify gene candidates for therapeutic targeting Research Perspective

Diana Monsivais, Sydney E. Parks, Darshan S. Chandrashekar, Sooryanarayana Varambally, Chad J. Creighton

Published Apr 28, 2023 · Vol. 14, No. 1 · pp. 399-412

Keywords: proteomics, proteogenomics, multi-omics, cancer, TTK protein kinase

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Retraction: LncRNA CHRFinduced miR-489 loss promotes metastasis of colorectal cancer via TWIST1/EMT signaling pathway Retraction

Retraction: Loss of FOXN3 in colon cancer activates beta-catenin/TCF signaling and promotes the growth and migration of cancer cells Retraction

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma Research Paper

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

Clinical and analytical validation of MI Cancer Seek^®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay Research Paper

Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms Review

Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors Review

Cigarette smoke and decreased DNA repair by Xeroderma Pigmentosum Group C use a double hit mechanism for epithelial cell lung carcinogenesis Research Paper

Signaling pathway dysregulation in breast cancer Review

Robust p53 phenotypes and prospective downstream targets in telomerase-immortalized human cells Research Paper

Leukopenia, weight loss and oral mucositis induced by 5-Fluorouracil in hamsters’ model: A regenerative approach using electrospun poly(Lactic-co-Glycolic Acid) membrane Research Paper

Molecular chaperones: Guardians of tumor suppressor stability and function Review

Linking FOXM1 and PD-L1 to CDK4/6-MEK targeted therapy resistance in malignant peripheral nerve sheath tumors Mini-Review

UBA1 dysfunction in VEXAS and cancer Research Perspective

Deep learning-based whole-body PSMA PET/CT attenuation correction utilizing Pix-2-Pix GAN Research Paper

Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples Research Paper

Addendum: Genomic landscape of metastatic breast cancer (MBC) patients with methylthioadenosine phosphorylase (MTAP) loss Addendum

Targeting H3K27me3 loss in pediatric brain tumors - a perspective on epigenetically guided cancer therapy Editorial

Using cancer proteomics data to identify gene candidates for therapeutic targeting Research Perspective

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Retraction: LncRNA CHRFinduced miR-489 loss promotes metastasis of colorectal cancer via TWIST1/EMT signaling pathway Retraction

Retraction: Loss of FOXN3 in colon cancer activates beta-catenin/TCF signaling and promotes the growth and migration of cancer cells Retraction

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma Research Paper

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

Clinical and analytical validation of MI Cancer Seek®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay Research Paper

Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms Review

Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors Review

Cigarette smoke and decreased DNA repair by Xeroderma Pigmentosum Group C use a double hit mechanism for epithelial cell lung carcinogenesis Research Paper

Signaling pathway dysregulation in breast cancer Review

Robust p53 phenotypes and prospective downstream targets in telomerase-immortalized human cells Research Paper

Leukopenia, weight loss and oral mucositis induced by 5-Fluorouracil in hamsters’ model: A regenerative approach using electrospun poly(Lactic-co-Glycolic Acid) membrane Research Paper

Molecular chaperones: Guardians of tumor suppressor stability and function Review

Linking FOXM1 and PD-L1 to CDK4/6-MEK targeted therapy resistance in malignant peripheral nerve sheath tumors Mini-Review

UBA1 dysfunction in VEXAS and cancer Research Perspective

Deep learning-based whole-body PSMA PET/CT attenuation correction utilizing Pix-2-Pix GAN Research Paper

Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples Research Paper

Addendum: Genomic landscape of metastatic breast cancer (MBC) patients with methylthioadenosine phosphorylase (MTAP) loss Addendum

Targeting H3K27me3 loss in pediatric brain tumors - a perspective on epigenetically guided cancer therapy Editorial

Using cancer proteomics data to identify gene candidates for therapeutic targeting Research Perspective

Clinical and analytical validation of MI Cancer Seek^®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay Research Paper