The Oncosearch | Oncotarget

Alexandra Jackovich, Barbara J. Gitlitz, Justin Wayne Wong Tiu-lim, Vinay Duddalwar, Kevin George King, Anthony B. El-Khoueiry, Jacob Stephen Thomas, Denice Tsao-Wei, David I. Quinn, Parkash S. Gill, Jorge J. Nieva

Published Jun 29, 2024 · Vol. 15, No. 1 · pp. 444-458

Keywords: EphrinB2, EphB4, HNSCC, pembrolizumab, HPV-negative

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation Research Perspective

Mark Lee, Luc GT Morris

Published Dec 15, 2023 · Vol. 15, No. 1 · pp. 36-48

Keywords: thyroid cancer, drug resistance, anaplastic transformation, BRAF inhibitors, PIK3CA

Oncogenic driver FGFR3-TACC3 requires five coiled-coil heptads for activation and disulfide bond formation for stability Research Paper

Clark G. Wang, Malalage N. Peiris, April N. Meyer, Katelyn N. Nelson, Daniel J. Donoghue

Published Feb 6, 2023 · Vol. 14, No. 1 · pp. 133-145

Keywords: oncogenic fusion protein, chromosomal translocation, glioblastoma, FGFR3-TACC3, coiled-coil

Everolimus downregulates STAT3/HIF-1α/VEGF pathway to inhibit angiogenesis and lymphangiogenesis in TP53 mutant head and neck squamous cell carcinoma (HNSCC) Research Paper

Md Maksudul Alam, Janmaris Marin Fermin, Mark Knackstedt, Mackenzie J. Noonan, Taylor Powell, Landon Goodreau, Emily K. Daniel, Xiaohua Rong, Tara Moore-Medlin, Alok R. Khandelwal, Cherie-Ann O. Nathan

Published Jan 27, 2023 · Vol. 14, No. 1 · pp. 85-95

Keywords: TP53 mutant, HNSCC, angiogenesis, everolimus, mTOR

Addendum: Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Addendum

Andy Karabajakian, Thibaut Garrivier, Carole Crozes, Nicolas Gadot, Jean-Yves Blay, Frédéric Bérard, Philippe Céruse, Philippe Zrounba, Pierre Saintigny, Charles Mastier, Jérôme Fayette

Published Nov 18, 2022 · Vol. 13, No. 1 · pp. 1305-1305

Nectin-4 is widely expressed in head and neck squamous cell carcinoma Research Paper

Christine Sanders, Jan-Frederic Lau, Dimo Dietrich, Sebastian Strieth, Peter Brossart, Glen Kristiansen

Published Oct 14, 2022 · Vol. 13, No. 1 · pp. 1166-1173

Keywords: Nectin-4, enfortumab-vedotin, HNSCC, p16

Continuous treatment with abemaciclib leads to sustained and efficient inhibition of breast cancer cell proliferation Research Paper

Raquel Torres-Guzmán, Maria Patricia Ganado, Cecilia Mur, Carlos Marugan, Carmen Baquero, Yanzhu Yang, Yi Zeng, Huimin Bian, Jian Du, Alfonso de Dios, Oscar Puig, María José Lallena

Published Jun 22, 2022 · Vol. 13, No. 1 · pp. 864-875

Keywords: abemaciclib, breast cancer, cell lines, CDK4/6, continuous dosing

NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer Research Paper

Travis P. Schrank, Andrew C. Prince, Tejas Sathe, Xiaowei Wang, Xinyi Liu, Damir T. Alzhanov, Barbara Burtness, Albert S. Baldwin, Wendell G. Yarbrough, Natalia Issaeva

Published May 7, 2022 · Vol. 13, No. 1 · pp. 707-722

Keywords: HPV, head and neck cancer, CYLD, TRAF3, NF-κB

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Pratima Nangia-Makker, Malathy P.V. Shekhar, Victor Hogan, Vitaly Balan, Avraham Raz

Published Mar 9, 2022 · Vol. 13, No. 1 · pp. 534-550

Keywords: myosin II, MYH9, dNTP, deoxyribose-5-phosphate, DNA synthesis

Seventh BHD international symposium: recent scientific and clinical advancement Meeting Report

Mark R. Woodford, Avgi Andreou, Masaya Baba, Irma van de Beek, Chiara Di Malta, Iris Glykofridis, Hannah Grimes, Elizabeth P. Henske, Othon Iliopoulos, Masatoshi Kurihara, Romain Lazor, W. Marston Linehan, Kenki Matsumoto, Stefan J. Marciniak, Yukiko Namba, Arnim Pause, Neil Rajan, Anindita Ray, Laura S. Schmidt, Wei Shi, Ortrud K. Steinlein, Julia Thierauf, Roberto Zoncu, Anna Webb, Mehdi Mollapour

Published Dec 30, 2021 · Vol. 13, No. 1 · pp. 173-181

Keywords: Birt-Hogg-Dubé syndrome, folliculin, FLCN, tuberous sclerosis complex, LDHA

Correction: Novel Akt activator SC-79 is a potential treatment for alcohol-induced osteonecrosis of the femoral head Correction

Yi-Xuan Chen, Shi-Cong Tao, Zheng-Liang Xu, Wen-Jing Yin, Yue-Lei Zhang, Jun-Hui Yin, You-Shui Gao, Chang-Qing Zhang

Published Nov 5, 2021

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Lara H. El Touny, Curtis Hose, John Connelly, Erik Harris, Anne Monks, Angie B. Dull, Deborah F. Wilsker, Melinda G. Hollingshead, Michelle Gottholm-Ahalt, Sergio Y. Alcoser, Michael E. Mullendore, Ralph E. Parchment, James H. Doroshow, Beverly A. Teicher, Annamaria Rapisarda

Published Sep 28, 2021 · Vol. 12, No. 21 · pp. 2114-2130

Keywords: TMZ, MMR, ATR, HR, REV3L

Switching Hedgehog inhibitors and other strategies to address resistance when treating advanced basal cell carcinoma Review

Hung Q. Doan, Leon Chen, Zeena Nawas, Heng-Huan Lee, Sirunya Silapunt, Michael Migden

Published Sep 13, 2021 · Vol. 12, No. 20 · pp. 2089-2100

Keywords: basal cell carcinoma, Hedgehog pathway inhibitor, resistance, switching, combination therapy

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Correction: The effectiveness of nano chemotherapeutic particles combined with mifepristone depends on the PR isoform ratio in preclinical models of breast cancer Correction

Hypothesis: HPV E6 and COVID spike proteins cooperate in targeting tumor suppression by p53 Hypothesis

Correction: Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells Correction

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms Review

Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells Research Paper

A case of adenosquamous pancreatic cancer with a KRAS G12C mutation with an exceptional response to immunotherapy Case Report

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation Research Perspective

Oncogenic driver FGFR3-TACC3 requires five coiled-coil heptads for activation and disulfide bond formation for stability Research Paper

Everolimus downregulates STAT3/HIF-1α/VEGF pathway to inhibit angiogenesis and lymphangiogenesis in TP53 mutant head and neck squamous cell carcinoma (HNSCC) Research Paper

Addendum: Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Addendum

Nectin-4 is widely expressed in head and neck squamous cell carcinoma Research Paper

Continuous treatment with abemaciclib leads to sustained and efficient inhibition of breast cancer cell proliferation Research Paper

NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer Research Paper

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Seventh BHD international symposium: recent scientific and clinical advancement Meeting Report

Correction: Novel Akt activator SC-79 is a potential treatment for alcohol-induced osteonecrosis of the femoral head Correction

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Switching Hedgehog inhibitors and other strategies to address resistance when treating advanced basal cell carcinoma Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Correction: The effectiveness of nano chemotherapeutic particles combined with mifepristone depends on the PR isoform ratio in preclinical models of breast cancer Correction

Hypothesis: HPV E6 and COVID spike proteins cooperate in targeting tumor suppression by p53 Hypothesis

Correction: Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells Correction

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms Review

Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells Research Paper

A case of adenosquamous pancreatic cancer with a KRAS G12C mutation with an exceptional response to immunotherapy Case Report

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation Research Perspective

Oncogenic driver FGFR3-TACC3 requires five coiled-coil heptads for activation and disulfide bond formation for stability Research Paper

Everolimus downregulates STAT3/HIF-1α/VEGF pathway to inhibit angiogenesis and lymphangiogenesis in TP53 mutant head and neck squamous cell carcinoma (HNSCC) Research Paper

Addendum: Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Addendum

Nectin-4 is widely expressed in head and neck squamous cell carcinoma Research Paper

Continuous treatment with abemaciclib leads to sustained and efficient inhibition of breast cancer cell proliferation Research Paper

NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer Research Paper

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Seventh BHD international symposium: recent scientific and clinical advancement Meeting Report

Correction: Novel Akt activator SC-79 is a potential treatment for alcohol-induced osteonecrosis of the femoral head Correction

ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide Priority Research Paper

Switching Hedgehog inhibitors and other strategies to address resistance when treating advanced basal cell carcinoma Review

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper