The Oncosearch | Oncotarget

COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms Review

Charlotte Kuperwasser, Wafik S. El-Deiry

Published Mar 30, 2026 · Vol. 17, No. 1 · pp. 1-29

Keywords: COVID, vaccine, cancer, infection, lymphoma, leukemia, sarcoma, carcinoma

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Joel Ohana, Uziel Sandler, Benjamin A. Weinberg, Stephen Liu, Yoram Devary

Published Dec 19, 2025 · Vol. 16, No. 1 · pp. 848-857

Keywords: mutant KRAS, Nerofe, ST2 Receptor, tumor immune microenvironment, nuclear immunomodulation

Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status Research Paper

Jun Zhang, Lanlan Zhou, Shuai Zhao, Wafik S. El-Deiry

Published Jun 24, 2024 · Vol. 15, No. 1 · pp. 424-438

Keywords: TAS102, regorafenib, ERK1/2, angiogenesis, microvessel density

Real time ex vivo chemosensitivity assay for pancreatic adenocarcinoma Research Paper

Dae Won Kim, Francisca Beato, Youngchul Kim, Alexandra F. Tassielli, Ruifan Dai, Jason W. Denbo, Pamela J. Hodul, Mokenge P. Malafa, Jason B. Fleming

Published Sep 7, 2023 · Vol. 14, No. 1 · pp. 811-818

Keywords: pancreatic cancer, sensitivity assay, chemotherapy

PRRX1 induces epithelial-mesenchymal transition in oesophageal cancer Research Paper

Jinbao Guo, Ming Du, Bin Wang, Li Zhong, Zhongxue Fu, Jinlai Wei

Published Mar 10, 2023

Keywords: PRRX1, oesophageal cancer, epithelial–mesenchymal transition, cancer metastasis

Serum microRNAs as new criteria for referral to early palliative care services in treatment-naïve advanced cancer patients Research Paper

Tomofumi Miura, Shuichi Mitsunaga, Juntaro Matsuzaki, Satoko Takizawa, Ken Kato, Atsushi Ochiai, Takahiro Ochiya

Published Nov 29, 2022 · Vol. 13, No. 1 · pp. 1341-1349

Keywords: microRNA, early palliative care, integration, cancer, referral

Serum microRNAs as new criteria for referral to early palliative care services in treatment-naïve advanced cancer patients Research Paper

Tomofumi Miura, Shuichi Mitsunaga, Juntaro Matsuzaki, Satoko Takizawa, Ken Kato, Atsushi Ochiai, Takahiro Ochiya

Published Nov 29, 2022

Keywords: microRNA, early palliative care, integration, cancer, referral

Plasma growth hormone is a potential biomarker of response to atezolizumab and bevacizumab in advanced hepatocellular carcinoma patients Research Paper

Yehia I. Mohamed, Dan G. Duda, Muhammad O. Awiwi, Sunyoung S. Lee, Lina Altameemi, Lianchun Xiao, Jeffrey S. Morris, Robert A. Wolff, Khaled M. Elsayes, Rikita I. Hatia, Aliya Qayyum, Shadi M. Chamseddine, Asif Rashid, James C. Yao, Armeen Mahvash, Manal M. Hassan, Hesham M. Amin, Ahmed Omar Kaseb

Published Nov 26, 2022 · Vol. 13, No. 1 · pp. 1314-1321

Keywords: growth hormone, hepatocellular carcinoma, immunotherapy, atezolizumab, bevacizumab

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study Research Paper

Jun Gong, Michelle Guan, Haesoo Kim, Natalie Moshayedi, Sejal Mehta, Galen Cook-Wiens, Brent K. Larson, Jenny Zhou, Rishi Patel, Isaac Lapite, Veronica R. Placencio-Hickok, Richard Tuli, Ronald B. Natale, Andrew E. Hendifar

Published Oct 25, 2022 · Vol. 13, No. 1 · pp. 1202-1214

Keywords: hyaluronan, hyaluronic acid, biomarker, prognostic, predictive

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more Review

Masahiko Shibata, Kotaro Nanno, Daigo Yoshimori, Takahiro Nakajima, Makoto Takada, Takashi Yazawa, Kousaku Mimura, Norio Inoue, Takafumi Watanabe, Kazunoshin Tachibana, Satoshi Muto, Tomoyuki Momma, Yoshiyuki Suzuki, Koji Kono, Shungo Endo, Seiichi Takenoshita

Published Oct 25, 2022 · Vol. 13, No. 1 · pp. 1273-1285

Keywords: MDSC, immunosuppression, Treg, TAM, cancer

Early-onset pancreatic cancer: a review of molecular mechanisms, management, and survival Review

Mark B. Ulanja, Alastair E. Moody, Bryce D. Beutler, Daniel Antwi-Amoabeng, Ganiyu A. Rahman, Olatunji B. Alese

Published Jun 4, 2022 · Vol. 13, No. 1 · pp. 828-841

Keywords: pancreatic cancer, gastrointestinal malignancy, epidemiology, pancreatic adenocarcinoma

Cytogenetic and molecular analyses of 291 gastrointestinal stromal tumors: site-specific cytogenetic evolution as evidence of pathogenetic heterogeneity Research Paper

Ludmila Gorunova, Kjetil Boye, Ioannis Panagopoulos, Jeanne-Marie Berner, Bodil Bjerkehagen, Ivar Hompland, Ingvild Lobmaier, Toto Hølmebakk, Tarjei S. Hveem, Sverre Heim, Francesca Micci

Published Feb 23, 2022 · Vol. 13, No. 1 · pp. 508-517

Keywords: gastrointestinal stromal tumor, chromosome aberrations, intratumor heterogeneity, KIT mutations, PDGFRA mutations

An investigation on [5 fluorouracil and epigallocatechin-3-gallate] complex activity on HT-29 cell death and its stability in gastrointestinal fluid Research Paper

Laura Moracci, Francesca Sensi, Andrea Biccari, Sara Crotti, Elisa Gaio, Federico Benetti, Pietro Traldi, Salvatore Pucciarelli, Marco Agostini

Published Feb 22, 2022 · Vol. 13, No. 1 · pp. 476-489

Keywords: HT29, 5-fluorouracil, epigallocatechin-3-gallate, molecular complexes, gastrointestinal model

The “Immunoscore” in rectal cancer: could we search quality beyond quantity of life? Research Perspective

Amos Kirilovsky, Carine El Sissy, Guy Zeitoun, Florence Marliot, Nacilla Haicheur, Christine Lagorce-Pagès, Julien Taieb, Mehdi Karoui, Petra Custers, Edina Dizdarevic, Soledad Iseas, Torben Frøstrup Hansen, Lars Henrik Jensen, Geerard Beets, Jean Pierre Gérard, Mireia Castillo-Martin, Nuno Figueiredo, Angelita Habr-Gama, Rodrigo Perez, Jérôme Galon, Franck Pagès

Published Oct 16, 2021 · Vol. 13, No. 1 · pp. 18-31

Keywords: rectal cancer, immunoscore, watch and wait, prognosis, radiochemotherapy

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

Austin R. Dosch, Walid K. Chatila, Yuguang Ban, Anna Bianchi, Nilesh U. Deshpande, Iago De Castro Silva, Nipun B. Merchant, Jashodeep Datta

Published Jun 1, 2021 · Vol. 12, No. 20 · pp. 2104-2110

Keywords: Ras-p53 cooperativity, Ras, TP53, immune, gastrointestinal cancer

CEA as a blood-based biomarker in anal cancer Research Paper

Robert Hester, Shailesh Advani, Asif Rashid, Emma Holliday, Craig Messick, Prajnan Das, Yi-Qian N. You, Cullen Taniguchi, Eugene J. Koay, Brian Bednarski, Miguel Rodriguez-Bigas, John Skibber, Robert Wolff, George J. Chang, Bruce D. Minsky, Wai Chin Foo, Nicole Rothschild, Van K. Morris, Cathy Eng

Published May 5, 2021 · Vol. 12, No. 11 · pp. 1037-1045

Keywords: carcinoembryonic antigen, squamous cell carcinoma of anal canal, anal cancer, biomarkers, HPV

Insulin-like growth factor 1/Child-Turcotte-Pugh composite score as a predictor of treatment outcomes in patients with advanced hepatocellular carcinoma treated with sorafenib Research Paper

Yehia I. Mohamed, Sunyoung Lee, Lianchun Xiao, Manal M. Hassan, Aliya Qayyum, Rikita Hiatia, Roberto Carmagnani Pestana, Abedul Haque, Bhawana George, Asif Rashid, Dan G. Duda, Hesham Elghazaly, Robert A. Wolff, Jeffrey S. Morris, James Yao, Hesham M. Amin, Ahmed O. Kaseb

Published Mar 13, 2021 · Vol. 12, No. 8 · pp. 756-766

Keywords: IGF-1, Child-Pugh, sorafenib, liver reserve, hepatocellular carcinoma

Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer Research Paper

Jared A. Sninsky, Kumar S. Bishnupuri, Iván González, Nikolaos A. Trikalinos, Ling Chen, Brian K. Dieckgraefe

Published Feb 8, 2021 · Vol. 12, No. 4 · pp. 278-291

Keywords: Reg4, CD44, CD44ICD, colorectal cancer

Extrahepatic cytochrome P450 epoxygenases: pathophysiology and clinical significance in human gastrointestinal cancers Review

Nataliya Pidkovka, Olena Rachkevych, Abbes Belkhiri

Published Feb 5, 2021 · Vol. 12, No. 4 · pp. 379-391

Keywords: cytochrome P450 epoxygenases, extrahepatic CYPs, gastrointestinal cancers, epoxyeicosatrienoic acids, arachidonic acid

Gastrointestinal stromal tumors (GISTs) and synchronous intra-abdominal malignancies: case series of a single institution’s experience Research Paper

Alexandros Diamantis, Athina A. Samara, Dimitrios Symeonidis, Ioannis Baloyiannis, Dionysia Vasdeki, Maria Tolia, Georgios Volakakis, Georgios Mavrovounis, Konstantinos Tepetes

Published Dec 17, 2020 · Vol. 11, No. 52 · pp. 4813-4821

Keywords: gastrointestinal stromal tumor, mesenchymal tumors, synchronous malignancies

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European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms Review

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status Research Paper

Real time ex vivo chemosensitivity assay for pancreatic adenocarcinoma Research Paper

PRRX1 induces epithelial-mesenchymal transition in oesophageal cancer Research Paper

Serum microRNAs as new criteria for referral to early palliative care services in treatment-naïve advanced cancer patients Research Paper

Serum microRNAs as new criteria for referral to early palliative care services in treatment-naïve advanced cancer patients Research Paper

Plasma growth hormone is a potential biomarker of response to atezolizumab and bevacizumab in advanced hepatocellular carcinoma patients Research Paper

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study Research Paper

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more Review

Early-onset pancreatic cancer: a review of molecular mechanisms, management, and survival Review

Cytogenetic and molecular analyses of 291 gastrointestinal stromal tumors: site-specific cytogenetic evolution as evidence of pathogenetic heterogeneity Research Paper

An investigation on [5 fluorouracil and epigallocatechin-3-gallate] complex activity on HT-29 cell death and its stability in gastrointestinal fluid Research Paper

The “Immunoscore” in rectal cancer: could we search quality beyond quantity of life? Research Perspective

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

CEA as a blood-based biomarker in anal cancer Research Paper

Insulin-like growth factor 1/Child-Turcotte-Pugh composite score as a predictor of treatment outcomes in patients with advanced hepatocellular carcinoma treated with sorafenib Research Paper

Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer Research Paper

Extrahepatic cytochrome P450 epoxygenases: pathophysiology and clinical significance in human gastrointestinal cancers Review

Gastrointestinal stromal tumors (GISTs) and synchronous intra-abdominal malignancies: case series of a single institution’s experience Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms Review

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status Research Paper

Real time ex vivo chemosensitivity assay for pancreatic adenocarcinoma Research Paper

PRRX1 induces epithelial-mesenchymal transition in oesophageal cancer Research Paper

Serum microRNAs as new criteria for referral to early palliative care services in treatment-naïve advanced cancer patients Research Paper

Serum microRNAs as new criteria for referral to early palliative care services in treatment-naïve advanced cancer patients Research Paper

Plasma growth hormone is a potential biomarker of response to atezolizumab and bevacizumab in advanced hepatocellular carcinoma patients Research Paper

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study Research Paper

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more Review

Early-onset pancreatic cancer: a review of molecular mechanisms, management, and survival Review

Cytogenetic and molecular analyses of 291 gastrointestinal stromal tumors: site-specific cytogenetic evolution as evidence of pathogenetic heterogeneity Research Paper

An investigation on [5 fluorouracil and epigallocatechin-3-gallate] complex activity on HT-29 cell death and its stability in gastrointestinal fluid Research Paper

The “Immunoscore” in rectal cancer: could we search quality beyond quantity of life? Research Perspective

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

CEA as a blood-based biomarker in anal cancer Research Paper

Insulin-like growth factor 1/Child-Turcotte-Pugh composite score as a predictor of treatment outcomes in patients with advanced hepatocellular carcinoma treated with sorafenib Research Paper

Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer Research Paper

Extrahepatic cytochrome P450 epoxygenases: pathophysiology and clinical significance in human gastrointestinal cancers Review

Gastrointestinal stromal tumors (GISTs) and synchronous intra-abdominal malignancies: case series of a single institution’s experience Research Paper