The Oncosearch | Oncotarget

Correction: The effectiveness of nano chemotherapeutic particles combined with mifepristone depends on the PR isoform ratio in preclinical models of breast cancer Correction

Gonzalo Sequeira, Silvia I Vanzulli, Paola Rojas, Caroline Lamb, Lucas Colombo, María May, Alfredo Molinolo, Claudia Lanari

Published Apr 1, 2026 · Vol. 17, No. 1 · pp. 137-138

COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms Review

Charlotte Kuperwasser, Wafik S. El-Deiry

Published Mar 30, 2026 · Vol. 17, No. 1 · pp. 1-29

Keywords: COVID, vaccine, cancer, infection, lymphoma, leukemia, sarcoma, carcinoma

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Joel Ohana, Uziel Sandler, Benjamin A. Weinberg, Stephen Liu, Yoram Devary

Published Dec 19, 2025 · Vol. 16, No. 1 · pp. 848-857

Keywords: mutant KRAS, Nerofe, ST2 Receptor, tumor immune microenvironment, nuclear immunomodulation

A personal perspective of patient-centred clinical trials Research Perspective

Trevor Tyne, Elizabeth Ivimey, Leanne Duggan, Jia Liu

Published Nov 5, 2025 · Vol. 16, No. 1 · pp. 808-812

Keywords: precision oncology, patient-centric care, clinical trials, tumor agnostic, drug development

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma Research Paper

Jacob Haagsma, Yudith Ramos Valdes, Xuejin Ou, Rasheduzzaman Rashu, S.M. Mansour Haeryfar, Jim Petrik, Trevor G. Shepherd

Published Sep 16, 2025 · Vol. 16, No. 1 · pp. 697-718

Keywords: high-grade serous ovarian carcinoma, orthotopic models, inflammation, microenvironment

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

Kristen Kwong, Yue Pan, Jacqueline Morales, Matthew Watson, David V. Allegakoen, Alex G. Lee, Trever G. Bivona, Peter Wipf, Christopher J. Guerriero, Jeffrey L. Brodsky, Amit J. Sabnis

Published Aug 23, 2025 · Vol. 16, No. 1 · pp. 681-696

Keywords: protein homeostasis, rhabdomyosarcoma, unfolded protein response, preclinical therapeutics, p97

Exceptional responders to immunotherapy in pancreatic cancer: A multi-institutional case series of a rare occurrence Research Paper

Kavin Sugumar, Andrew Alabd, Andre Alabd, Jonathan J. Hue, Josh Lyons, Sherri Fields, Zev Wainberg, Lei Zheng, Brianna Coogle, Anup Kasi, Nicholas Grewal, Hedy L. Kindler, Jason Starr, Ashwin R. Sama, Jordan M. Winter

Published Jun 3, 2025 · Vol. 16, No. 1 · pp. 427-442

Keywords: pancreatic adenocarcinoma, immunotherapy, exceptional responders, microsatellite instability, survival

Cigarette smoke and decreased DNA repair by Xeroderma Pigmentosum Group C use a double hit mechanism for epithelial cell lung carcinogenesis Research Paper

Nawar Al Nasrallah, Bowa Lee, Benjamin M. Wiese, Marie N. Karam, Elizabeth A. Mickler, Huaxin Zhou, Nicki Paolelli, Robert S. Stearman, Mark W. Geraci, Catherine R. Sears

Published May 9, 2025 · Vol. 16, No. 1 · pp. 396-409

Keywords: DNA repair, DNA damage, lung adenocarcinoma, squamous cell carcinoma, Xeroderma Pigmentosum Group C (XPC)

Immune-mediated adverse events following atezolizumab and bevacizumab in a multinational Latin American cohort of unresectable hepatocellular carcinoma Research Paper

Leonardo Gomes da Fonseca, Federico Piñero, Margarita Anders, Carla Bermudez, Ezequiel Demirdjian, Adriana Varón, Daniela Perez, Jorge Rodriguez, Oscar Beltrán, Ezequiel Ridruejo, Pablo Caballini, Alexandre Araujo, Juan Diego Torres Florez, Juan Ignacio Marín, Marina Villa, Federico Orozco, Jaime Poniachik, Sebastián Marciano, Fernando Bessone, Manuel Mendizabal

Published May 8, 2025 · Vol. 16, No. 1 · pp. 348-360

Keywords: liver cancer, immunotherapy, adverse events, immunology, real-world

Analytical validation of a circulating tumor DNA assay using PhasED-Seq technology for detecting residual disease in B-cell malignancies Research Paper

Nina Klimova, Sandra Close, David M. Kurtz, Richard D. Hockett, Laura Hyland

Published May 2, 2025 · Vol. 16, No. 1 · pp. 329-336

Keywords: MRD, ctDNA, PhasED-Seq, CLARITY, residual disease

NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma Research Paper

Andrea Gunnell, Scott T. Kimber, Richard Houlston, Martin Kaiser

Published Mar 16, 2025 · Vol. 16, No. 1 · pp. 220-229

Keywords: myeloma, NSD2, t(4;14), CD38, plasma cell

Worldwide Innovative Network (WIN) Consortium in Personalized Cancer Medicine: Bringing next-generation precision oncology to patients Precision Oncology

Wafik S. El-Deiry, Catherine Bresson, Fanny Wunder, Benedito A. Carneiro, Don S. Dizon, Jeremy L. Warner, Stephanie L. Graff, Christopher G. Azzoli, Eric T. Wong, Liang Cheng, Sendurai A. Mani, Howard P. Safran, Casey Williams, Tobias Meissner, Benjamin Solomon, Eitan Rubin, Angel Porgador, Guy Berchem, Pierre Saintigny, Amir Onn, Jair Bar, Raanan Berger, Manon Gantenbein, Zhen Chen, Cristiano de Pádua Souza, Rui Manuel Vieira Reis, Marina Sekacheva, Andrés Cervantes, William L. Dahut, Christina M. Annunziata, Kerri Gober, Khaled M. Musallam, Humaid O. Al-Shamsi, Ibrahim Abu-Gheida, Ramon Salazar, Sewanti Limaye, Adel T. Aref, Roger R. Reddel, Mohammed Ussama Al Homsi, Abdul Rouf, Said Dermime, Jassim Al Suwaidi, Catalin Vlad, Rares Buiga, Amal Al Omari, Hikmat Abdel-Razeq, Luis F. Oñate-Ocaña, Finn Cilius Nielsen, Leah Graham, Jens Rueter, Anthony M. Joshua, Eugenia Girda, Steven Libutti, Gregory Riedlinger, Mohammed E. Salem, Carol J. Farhangfar, Ruben A. Mesa, Bishoy M. Faltas, Olivier Elemento, C.S. Pramesh, Manju Sengar, Satoru Aoyama, Sadakatsu Ikeda, Ioana Berindan-Neagoe, Himabindu Gaddipati, Mandar Kulkarni, Elisabeth Auzias, Maria Gerogianni, Nicolas Wolikow, Simon Istolainen, Pessie Schlafrig, Naftali Z. Frankel, Amanda R. Ferraro, Jim Palma, Alejandro Piris Gimenez, Alberto Hernando-Calvo, Enriqueta Felip, Apostolia M. Tsimberidou, Roy S. Herbst, Josep Tabernero, Richard L. Schilsky, Jia Liu, Yves Lussier, Jacques Raynaud, Gerald Batist, Shai Magidi, Razelle Kurzrock

Published Mar 12, 2025 · Vol. 16, No. 1 · pp. 140-162

Keywords: precision oncology, N-of-1 basket trials, AI algorithms, digital pathology, drug access

A case report of donor cell–derived hematologic neoplasms 9 years after allogeneic hematopoietic cell transplantation Case Report

Aleksandra Mroczkowska-Bękarciak, Tomasz Wróbel

Published Jan 28, 2025 · Vol. 16, No. 1 · pp. 44-50

Keywords: hematology, donor cell-derived hematologic neoplasms, genetics

Trained and ready - the case for an inflammatory memory for hematopoietic stem and progenitor cells in the AML niche Research Perspective

Ding-Wen Chen, Eric K. Wafula, Peter Kurre

Published Aug 17, 2024 · Vol. 15, No. 1 · pp. 609-613

Keywords: hematopoietic stem and progenitor cells, acute myeloid leukemia, inflammation, innate immune reprogramming, trained immunity

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma Research Paper

Caroline Naomi Valdez, Gabriela Athziri Sánchez-Zuno, Lais Osmani, Wael Ibrahim, Anjela Galan, Antonietta Bacchiocchi, Ruth Halaban, Rajan P. Kulkarni, Insoo Kang, Richard Bucala, Thuy Tran

Published Jul 15, 2024 · Vol. 15, No. 1 · pp. 507-520

Keywords: MIF, DDT, melanoma, immune checkpoint inhibition, cancer transcriptomics

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death Research Paper

Chantal L. Duurland, Thijs de Gunst, Harm C. den Boer, Marion T.J. van den Bosch, Bryony J. Telford, Rogier M. Vos, Xiaolei Xie, Mingfa Zang, Fang Wang, Yingying Shao, Xiaoyu An, Jingjing Wang, Jie Cai, Ludovic Bourré, Laurens A.H. van Pinxteren, Roel Q.J. Schaapveld, Michel Janicot, Sanaz Yahyanejad

Published Jul 4, 2024 · Vol. 15, No. 1 · pp. 470-485

Keywords: miR-193a-3p, microRNA mimic, T cell mediated immunity, immunogenic cell death, cancer

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper

Alexandra Jackovich, Barbara J. Gitlitz, Justin Wayne Wong Tiu-lim, Vinay Duddalwar, Kevin George King, Anthony B. El-Khoueiry, Jacob Stephen Thomas, Denice Tsao-Wei, David I. Quinn, Parkash S. Gill, Jorge J. Nieva

Published Jun 29, 2024 · Vol. 15, No. 1 · pp. 444-458

Keywords: EphrinB2, EphB4, HNSCC, pembrolizumab, HPV-negative

Using early on-treatment circulating tumor DNA measurements as response assessment in metastatic castration resistant prostate cancer Editorial

S.H. Tolmeijer, E. Boerrigter, N.P. Van Erp, Niven Mehra

Published Jun 19, 2024 · Vol. 15, No. 1 · pp. 421-423

Keywords: ctDNA, prostate cancer, liquid biopsy, biomarker, androgen receptor pathway inhibitors

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer Research Paper

Haven R. Garber, Sreyashi Basu, Sonali Jindal, Zhong He, Khoi Chu, Akshara Singareeka Raghavendra, Clinton Yam, Lumarie Santiago, Beatriz E. Adrada, Padmanee Sharma, Elizabeth A. Mittendorf, Jennifer K. Litton

Published Mar 2, 2024 · Vol. 15, No. 1 · pp. 238-247

Keywords: breast cancer, ER positive, immunotherapy, neoadjuvant chemotherapy, tumor microenvironment

Bone marrow adipocytes provide early sign for progression from MGUS to multiple myeloma Research Perspective

Bilal M. El-Masri, Benedeta Leka, Fatima Mustapha, Michael Tveden Gundesen, Maja Hinge, Thomas Lund, Thomas L. Andersen, Marta Diaz-delCastillo, Abbas Jafari

Published Jan 2, 2024 · Vol. 15, No. 1 · pp. 20-26

Keywords: multiple myeloma, MGUS, bone marrow adipocyte

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Correction: The effectiveness of nano chemotherapeutic particles combined with mifepristone depends on the PR isoform ratio in preclinical models of breast cancer Correction

COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms Review

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

A personal perspective of patient-centred clinical trials Research Perspective

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma Research Paper

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

Exceptional responders to immunotherapy in pancreatic cancer: A multi-institutional case series of a rare occurrence Research Paper

Cigarette smoke and decreased DNA repair by Xeroderma Pigmentosum Group C use a double hit mechanism for epithelial cell lung carcinogenesis Research Paper

Immune-mediated adverse events following atezolizumab and bevacizumab in a multinational Latin American cohort of unresectable hepatocellular carcinoma Research Paper

Analytical validation of a circulating tumor DNA assay using PhasED-Seq technology for detecting residual disease in B-cell malignancies Research Paper

NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma Research Paper

Worldwide Innovative Network (WIN) Consortium in Personalized Cancer Medicine: Bringing next-generation precision oncology to patients Precision Oncology

A case report of donor cell–derived hematologic neoplasms 9 years after allogeneic hematopoietic cell transplantation Case Report

Trained and ready - the case for an inflammatory memory for hematopoietic stem and progenitor cells in the AML niche Research Perspective

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma Research Paper

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death Research Paper

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper

Using early on-treatment circulating tumor DNA measurements as response assessment in metastatic castration resistant prostate cancer Editorial

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer Research Paper

Bone marrow adipocytes provide early sign for progression from MGUS to multiple myeloma Research Perspective

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Correction: The effectiveness of nano chemotherapeutic particles combined with mifepristone depends on the PR isoform ratio in preclinical models of breast cancer Correction

COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms Review

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

A personal perspective of patient-centred clinical trials Research Perspective

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma Research Paper

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

Exceptional responders to immunotherapy in pancreatic cancer: A multi-institutional case series of a rare occurrence Research Paper

Cigarette smoke and decreased DNA repair by Xeroderma Pigmentosum Group C use a double hit mechanism for epithelial cell lung carcinogenesis Research Paper

Immune-mediated adverse events following atezolizumab and bevacizumab in a multinational Latin American cohort of unresectable hepatocellular carcinoma Research Paper

Analytical validation of a circulating tumor DNA assay using PhasED-Seq technology for detecting residual disease in B-cell malignancies Research Paper

NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma Research Paper

Worldwide Innovative Network (WIN) Consortium in Personalized Cancer Medicine: Bringing next-generation precision oncology to patients Precision Oncology

A case report of donor cell–derived hematologic neoplasms 9 years after allogeneic hematopoietic cell transplantation Case Report

Trained and ready - the case for an inflammatory memory for hematopoietic stem and progenitor cells in the AML niche Research Perspective

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma Research Paper

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death Research Paper

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper

Using early on-treatment circulating tumor DNA measurements as response assessment in metastatic castration resistant prostate cancer Editorial

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer Research Paper

Bone marrow adipocytes provide early sign for progression from MGUS to multiple myeloma Research Perspective