The Oncosearch | Oncotarget

Long noncoding RNA H19 indicates a poor prognosis of colorectal cancer and promotes tumor growth by recruiting and binding to eIF4A3 Research Paper

Dong Han, Xu Gao, Meng Wang, Yu Qiao, Ya Xu, Jing Yang, Nazhen Dong, Jun He, Qian Sun, Guixiang Lv, Changqing Xu, Ji Tao, Ning Ma

Published Mar 14, 2016 · Vol. 7, No. 16 · pp. 22159-22173

4EGI-1 induces apoptosis and enhances radiotherapy sensitivity in nasopharyngeal carcinoma cells via DR5 induction on 4E-BP1 dephosphorylation Research Paper

Weiyuan Wang, Jiao Li, Qiuyuan Wen, Jiadi Luo, Shuzhou Chu, Lingjiao Chen, Zhenzhen Qing, Guiyuan Xie, Lina Xu, Mohannad Ma Alnemah, Meirong Li, Songqing Fan, Hongbo Zhang

Published Mar 1, 2016 · Vol. 7, No. 16 · pp. 21728-21741

MicroRNAs 125a and 125b inhibit ovarian cancer cells through post-transcriptional inactivation of EIF4EBP1 Research Paper

Maria Lee, Eun Jae Kim, Myung Jae Jeon

Published Dec 5, 2015 · Vol. 7, No. 8 · pp. 8726-8742

Key contribution of eIF4H-mediated translational control in tumor promotion Research Paper

Charlotte Vaysse, CÃ©line Philippe, Yvan Martineau, Cathy Quelen, Corinne Hieblot, Claire Renaud, Yvan Nicaise, Aurore Desquesnes, Maria Pannese, Thomas Filleron, Ghislaine Escourrou, Malcolm Lawson, Robert C Rintoul, Marie Bernadette Delisle, StÃ©phane Pyronnet, Pierre Brousset, HervÃ© Prats, Christian Touriol

Published Oct 15, 2015 · Vol. 6, No. 37 · pp. 39924-39940

eIF4E binding protein 1 expression is associated with clinical survival outcomes in colorectal cancer Research Paper

Min-Wu Chao, Li-Ting Wang, Chin-Yu Lai, Xiao-Ming Yang, Ya-Wen Cheng, Kuo-Hsiung Lee, Shiow-Lin Pan, Che-Ming Teng

Published Jun 29, 2015 · Vol. 6, No. 27 · pp. 24092-24104

Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells Research Paper

Jiayi Wang, Lifang Ma, Xun Tang, Xiao Zhang, Yongxia Qiao, Yuling Shi, Yanfeng Xu, Zhongyong Wang, Yongchun Yu, Fenyong Sun

Published Jun 8, 2015 · Vol. 6, No. 27 · pp. 24075-24091

Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3 Research Paper

Baolai Zhang, Shuhong Dong, Ruiming Zhu, Chunyan Hu, Jing Hou, Yan Li, Qian Zhao, Xue Shao, Qian Bu, Hongyu Li, Yongjie Wu, Xiaobo Cen, Yinglan Zhao

Published Jun 2, 2015 · Vol. 6, No. 26 · pp. 22799-22811

Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL Research Paper

Filomena De Falco, Rita Sabatini, Beatrice Del Papa, Franca Falzetti, Mauro Di Ianni, Paolo Sportoletti, Stefano Baldoni, Isabella Screpanti, Pierfrancesco Marconi, Emanuela Rosati

Published May 12, 2015 · Vol. 6, No. 18 · pp. 16559-16572

RPPA-based protein profiling reveals eIF4G overexpression and 4E-BP1 serine 65 phosphorylation as molecular events that correspond with a pro-survival phenotype in chronic lymphocytic leukemia Research Paper

Austin Y. Shull, Satish K. Noonepalle, Farrukh T. Awan, Jimei Liu, Lirong Pei, Roni J. Bollag, Huda Salman, Zhiyong Ding, Huidong Shi

Published May 12, 2015 · Vol. 6, No. 16 · pp. 14632-14645

Small-molecule induction of phospho-eIF4E sumoylation and degradation via targeting its phosphorylated serine 209 residue Research Paper

Ying Gu, Hong Zhou, Yichao Gan, Jiawei Zhang, Jianghua Chen, Xiaoxian Gan, Hongzhi Li, Weiwei Zheng, Zhipeng Meng, Xiaoxiao Ma, Xichun Wang, Xiaohua Xu, Ganyu Xu, Xiaoya Lu, Yun Liang, Xuzhao Zhang, Xinliang Lu, Wendong Huang, Rongzhen Xu

Published Apr 10, 2015 · Vol. 6, No. 17 · pp. 15111-15121

Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma Research Paper

Christos Demosthenous, Jing Jing Han, Mary J. Stenson, Matthew J. Maurer, Linda E. Wellik, Brian Link, Kristen Hege, Ahmet Dogan, Eduardo Sotomayor, Thomas Witzig, Mamta Gupta

Published Mar 20, 2015 · Vol. 6, No. 11 · pp. 9488-9501

FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia Research Paper

Ayako Nogami, Gaku Oshikawa, Keigo Okada, Shusaku Fukutake, Yoshihiro Umezawa, Toshikage Nagao, Tetsuya Kurosu, Osamu Miura

Published Mar 16, 2015 · Vol. 6, No. 11 · pp. 9189-9205

eIF4E and eIF4GI have distinct and differential imprints on multiple myeloma's proteome and signaling Research Paper

Oshrat Attar-Schneider, Metsada Pasmanik-Chor, Shelly Tartakover-Matalon, Liat Drucker, Michael Lishner

Published Jan 29, 2015 · Vol. 6, No. 6 · pp. 4315-4329

Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion Research Paper

Long Chen, Baoshan Xu, Lei Liu, Chunxiao Liu, Yan Luo, Xin Chen, Mansoureh Barzegar, Jun Chung, Shile Huang

Published Jan 23, 2015 · Vol. 6, No. 9 · pp. 7136-7150

Simultaneous targeting of androgen receptor (AR) and MAPK-interacting kinases (MNKs) by novel retinamides inhibits growth of human prostate cancer cell lines Research Paper

Vidya P. Ramamurthy, Senthilmurugan Ramalingam, Lalji Gediya, Andrew K. Kwegyir-Afful, Vincent C.O. Njar

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3195-3210

Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation Research Paper

Seong-Jun Cho, I-Fang Teng, Min Zhang, Tiffany Yin, Yong-Sam Jung, Jin Zhang, Xinbin Chen

Published Nov 16, 2014 · Vol. 6, No. 1 · pp. 305-316

Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells Research Paper

Frank Eckerdt, Elspeth Beauchamp, Jonathan Bell, Asneha Iqbal, Bing Su, Rikiro Fukunaga, Rishi R. Lulla, Stewart Goldman, Leonidas C. Platanias

Published Aug 6, 2014 · Vol. 5, No. 18 · pp. 8442-8451

Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73 Research Paper

Frankie Lam, Abdullahi Y. Abbas, Hao Shao, Theodosia Teo, Julian Adams, Peng Li, Tracey D. Bradshaw, Peter M. Fischer, Elisabeth Walsby, Chris Pepper, Yi Chen, Jian Ding, Shudong Wang

Published Jul 31, 2014 · Vol. 5, No. 17 · pp. 7691-7704

4EGI-1 targets breast cancer stem cells by selective inhibition of translation that persists in CSC maintenance, proliferation and metastasis Research Paper

Tingfang Yi, Eihab Kabha, Evangelos Papadopoulos, Gerhard Wagner

Published Jun 18, 2014 · Vol. 5, No. 15 · pp. 6028-6037

RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth Research Paper

Kathleen A. Wilson-Edell, Amanuel Kehasse, Gary K. Scott, Christina Yau, Daniel E. Rothschild, Birgit Schilling, Bianca S. Gabriel, Mariya A. Yevtushenko, Ingrid M. Hanson, Jason M. Held, Bradford W. Gibson, Christopher C. Benz

Published Jun 12, 2014 · Vol. 5, No. 13 · pp. 5165-5176

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Long noncoding RNA H19 indicates a poor prognosis of colorectal cancer and promotes tumor growth by recruiting and binding to eIF4A3 Research Paper

4EGI-1 induces apoptosis and enhances radiotherapy sensitivity in nasopharyngeal carcinoma cells via DR5 induction on 4E-BP1 dephosphorylation Research Paper

MicroRNAs 125a and 125b inhibit ovarian cancer cells through post-transcriptional inactivation of EIF4EBP1 Research Paper

Key contribution of eIF4H-mediated translational control in tumor promotion Research Paper

eIF4E binding protein 1 expression is associated with clinical survival outcomes in colorectal cancer Research Paper

Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells Research Paper

Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3 Research Paper

Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL Research Paper

RPPA-based protein profiling reveals eIF4G overexpression and 4E-BP1 serine 65 phosphorylation as molecular events that correspond with a pro-survival phenotype in chronic lymphocytic leukemia Research Paper

Small-molecule induction of phospho-eIF4E sumoylation and degradation via targeting its phosphorylated serine 209 residue Research Paper

Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma Research Paper

FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia Research Paper

eIF4E and eIF4GI have distinct and differential imprints on multiple myeloma's proteome and signaling Research Paper

Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion Research Paper

Simultaneous targeting of androgen receptor (AR) and MAPK-interacting kinases (MNKs) by novel retinamides inhibits growth of human prostate cancer cell lines Research Paper

Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation Research Paper

Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells Research Paper

Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73 Research Paper

4EGI-1 targets breast cancer stem cells by selective inhibition of translation that persists in CSC maintenance, proliferation and metastasis Research Paper

RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Long noncoding RNA H19 indicates a poor prognosis of colorectal cancer and promotes tumor growth by recruiting and binding to eIF4A3 Research Paper

4EGI-1 induces apoptosis and enhances radiotherapy sensitivity in nasopharyngeal carcinoma cells via DR5 induction on 4E-BP1 dephosphorylation Research Paper

MicroRNAs 125a and 125b inhibit ovarian cancer cells through post-transcriptional inactivation of EIF4EBP1 Research Paper

Key contribution of eIF4H-mediated translational control in tumor promotion Research Paper

eIF4E binding protein 1 expression is associated with clinical survival outcomes in colorectal cancer Research Paper

Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells Research Paper

Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3 Research Paper

Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL Research Paper

RPPA-based protein profiling reveals eIF4G overexpression and 4E-BP1 serine 65 phosphorylation as molecular events that correspond with a pro-survival phenotype in chronic lymphocytic leukemia Research Paper

Small-molecule induction of phospho-eIF4E sumoylation and degradation via targeting its phosphorylated serine 209 residue Research Paper

Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma Research Paper

FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia Research Paper

eIF4E and eIF4GI have distinct and differential imprints on multiple myeloma's proteome and signaling Research Paper

Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion Research Paper

Simultaneous targeting of androgen receptor (AR) and MAPK-interacting kinases (MNKs) by novel retinamides inhibits growth of human prostate cancer cell lines Research Paper

Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation Research Paper

Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells Research Paper

Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73 Research Paper

4EGI-1 targets breast cancer stem cells by selective inhibition of translation that persists in CSC maintenance, proliferation and metastasis Research Paper

RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth Research Paper