The Oncosearch | Oncotarget

Inhibitory effects of Tomivosertib in acute myeloid leukemia Research Paper

Milagros Suarez, Gavin T. Blyth, Alain A. Mina, Ewa M. Kosciuczuk, Blazej Dolniak, Shira Dinner, Jessica K. Altman, Elizabeth A. Eklund, Diana Saleiro, Elspeth M. Beauchamp, Leonidas C. Platanias

Published Apr 24, 2021 · Vol. 12, No. 10 · pp. 955-966

Keywords: MNK, Tomivosertib, acute myeloid leukemia, eIF4E

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

Christelle Morris, Sébastien Durand, Pierre Jalinot

Published Mar 13, 2021 · Vol. 12, No. 7 · pp. 649-664

Keywords: breast cancer, senescence-associated secretory phenotype, eIF3, PARP1, mTORC1

Important players in carcinogenesis as potential targets in cancer therapy: an update Review

Justyna Magdalena Hermanowicz, Iwona Kwiatkowska, Dariusz Pawlak

Published Jul 21, 2020 · Vol. 11, No. 32 · pp. 3078-3101

Keywords: modulators of carcinogenesis, acetylcholine, peroxisome proliferator-activated receptors, aquaporins

Inhibitory effects of SEL201 in acute myeloid leukemia Research Paper

Ewa M. Kosciuczuk, Aroop K. Kar, Gavin T. Blyth, Mariafausta Fischietti, Sameem Abedin, Alain A. Mina, Rebekah Siliezar, Tomasz Rzymski, Krzysztof Brzozka, Elizabeth A. Eklund, Elspeth M. Beauchamp, Frank Eckerdt, Diana Saleiro, Leonidas C. Platanias

Published Dec 24, 2019 · Vol. 10, No. 67 · pp. 7112-7121

Keywords: acute myeloid leukemia, MNK, eIF4E, kinase inhibitor, SEL201

Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma Research Paper

Osamu Ichiyanagi, Hiromi Ito, Sei Naito, Takanobu Kabasawa, Hidenori Kanno, Takafumi Narisawa, Masaki Ushijima, Yuta Kurota, Michinobu Ozawa, Toshihiko Sakurai, Hayato Nishida, Tomoyuki Kato, Mitsunori Yamakawa, Norihiko Tsuchiya

Published Jun 18, 2019 · Vol. 10, No. 40 · pp. 4053-4068

Keywords: renal cell carcinoma, phospho-eIF4E (p-eIF4E), MNK (MAPK-interacting kinase), recurrence-free, epithelial−mesenchymal transition

A DNA telomerase vaccine for canine cancer immunotherapy Research Paper

Jessie Thalmensi, Elodie Pliquet, Christelle Liard, Gabriel Chamel, Christine Kreuz, Thomas Bestetti, Marie Escande, Anna Kostrzak, Anne-Sophie Pailhes-Jimenez, Emmanuèle Bourges, Marion Julithe, Ludovic Bourre, Olivier Keravel, Pascal Clayette, Thierry Huet, Simon Wain-Hobson, Pierre Langlade-Demoyen

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3361-3372

Keywords: DNA vaccine, canine TERT, cancer, immunotherapy, Electro-Gene-Transfer

Pulsed SILAC-based proteomic analysis unveils hypoxia- and serum starvation-induced de novo protein synthesis with PHD finger protein 14 (PHF14) as a hypoxia sensitive epigenetic regulator in cell cycle progression Research Paper

Jung Eun Park, Shun Wilford Tse, Guo Xue, Christina Assisi, Aida Serra Maqueda, Gallart Palau Xavier Ramon, Jee Keem Low, Oi Lian Kon, Chor Yong Tay, James P. Tam, Siu Kwan Sze

Published Mar 15, 2019 · Vol. 10, No. 22 · pp. 2136-2150

Integrated landscape of copy number variation and RNA expression associated with nodal metastasis in invasive ductal breast carcinoma Research Paper

Michael Behring, Sadeep Shrestha, Upender Manne, Xiangqin Cui, Agustin Gonzalez-Reymundez, Alexander Grueneberg, Ana I. Vazquez

Published Dec 7, 2018 · Vol. 9, No. 96 · pp. 36836-36848

Correction: Targeting Hsp27/eIF4E interaction with phenazine compound: a promising alternative for castration-resistant prostate cancer treatment Correction

Hajer Ziouziou, Claudia Andrieu, Erik Laurini, Sara Karaki, Maurizio Fermeglia, Ridha Oueslati, David Taieb, Michel Camplo, Olivier Siri, Sabrina Pricl, Maria Katsogiannou, Palma Rocchi

Published Jun 18, 2018 · Vol. 9, No. 47 · pp. 28797-28797

Synergistic effects of inhibiting the MNK-eIF4E and PI3K/AKT/ mTOR pathways on cell migration in MDA-MB-231 cells Research Paper

Ella Lineham, Graham J. Tizzard, Simon J. Coles, John Spencer, Simon J. Morley

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14148-14159

Increased expression of MNK1b, the spliced isoform of MNK1, predicts poor prognosis and is associated with triple-negative breast cancer Research Paper

Celia Pinto-DÃez, Eva M. GarcÃa-Recio, M. Isabel PÃ©rez-Morgado, Marta GarcÃa-HernÃ¡ndez, Lara Sanz-Criado, Silvia SacristÃ¡n, M. Val Toledo-Lobo, BelÃ©n PÃ©rez-Mies, Isabel Esteban-RodrÃguez, Alejandro Pascual, Mercedes Garcia-Villanueva, Noelia MartÃnez-JaÃ±ez, VÃctor M. GonzÃ¡lez, M. Elena MartÃn

Published Feb 5, 2018 · Vol. 9, No. 17 · pp. 13501-13516

Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress Research Paper

Xiangyun Li, Mei Li, Hang Ruan, Wei Qiu, Xiang Xu, Lin Zhang, Jian Yu

Published Jan 22, 2018 · Vol. 8, No. 6 · pp. 9280-9292

Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors Research Paper

Joshua Casaos, Sakibul Huq, Tarik Lott, Raphael Felder, John Choi, Noah Gorelick, Michael Peters, Yuanxuan Xia, Russell Maxwell, Tianna Zhao, Chenchen Ji, Thomas Simon, Julie Sesen, Sarah J. Scotland, Richard E. Kast, Jeffrey Rubens, Eric Raabe, Charles G. Eberhart, Eric M. Jackson, Henry Brem, Betty Tyler, Nicolas Skuli

Published Jan 3, 2018 · Vol. 9, No. 8 · pp. 8054-8067

Proteomic analysis of chicken embryo fibroblast cells infected with recombinant H5N1 avian influenza viruses with and without NS1 eIF4GI binding domain Research Paper

Kelei Guo, Xian Lin, Yongtao Li, Wei Qian, Zhong Zou, Huanchun Chen, Hongbo Zhou, Meilin Jin

Published Dec 22, 2017 · Vol. 9, No. 9 · pp. 8350-8367

FLT3-ITD induces expression of Pim kinases through STAT5 to confer resistance to the PI3K/Akt pathway inhibitors on leukemic cells by enhancing the mTORC1/Mcl-1 pathway Research Paper

Keigo Okada, Ayako Nogami, Shinya Ishida, Hiroki Akiyama, Cheng Chen, Yoshihiro Umezawa, Osamu Miura

Published Dec 4, 2017 · Vol. 9, No. 10 · pp. 8870-8886

Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6 Research Paper

Nicole Golob-Schwarzl, Caroline Schweiger, Carina Koller, Stefanie Krassnig, Margit Gogg-Kamerer, Nadine Gantenbein, Anna M. Toeglhofer, Christina Wodlej, Helmut Bergler, Brigitte Pertschy, Stefan Uranitsch, Magdalena Holter, Amin El-Heliebi, Julia Fuchs, Andreas Punschart, Philipp Stiegler, Marlen Keil, Jens Hoffmann, David Henderson, Hans Lehrach, Christoph Reinhard, Christian Regenbrecht, Rudolf Schicho, Peter Fickert, Sigurd Lax, Johannes Haybaeck

Published Sep 5, 2017 · Vol. 8, No. 60 · pp. 101224-101243

Targeting Hsp27/eIF4E interaction with phenazine compound: a promising alternative for castration-resistant prostate cancer treatment Research Paper

Hajer Ziouziou, Claudia Andrieu, Erik Laurini, Sara Karaki, Maurizio Fermeglia, Ridha Oueslati, David Taieb, Michel Camplo, Olivier Siri, Sabrina Pricl, Maria Katsogiannou, Palma Rocchi

Published Aug 24, 2017 · Vol. 8, No. 44 · pp. 77317-77329

Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo Research Paper

Chih-Chia Yu, Shih-Kai Hung, Hon-Yi Lin, Wen-Yen Chiou, Moon-Sing Lee, Hui-Fen Liao, Hsien-Bin Huang, Hsu-Chueh Ho, Yu-Chieh Su

Published Aug 2, 2017 · Vol. 8, No. 40 · pp. 68641-68653

Cap-dependent translational control of oncolytic measles virus infection in malignant mesothelioma Research Paper

Blake A. Jacobson, Ahad A. Sadiq, Shaogeng Tang, Joe Jay-Dixon, Manish R. Patel, Jeremy Drees, Brent S. Sorenson, Stephen J. Russell, Robert A. Kratzke

Published Jun 27, 2017 · Vol. 8, No. 38 · pp. 63096-63109

Targeting EIF4F complex in non-small cell lung cancer cells Review

Lu Dai, Zhen Lin, Yueyu Cao, Yihan Chen, Zengguang Xu, Zhiqiang Qin

Published Jun 8, 2017 · Vol. 8, No. 33 · pp. 55731-55735

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Inhibitory effects of Tomivosertib in acute myeloid leukemia Research Paper

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

Important players in carcinogenesis as potential targets in cancer therapy: an update Review

Inhibitory effects of SEL201 in acute myeloid leukemia Research Paper

Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma Research Paper

A DNA telomerase vaccine for canine cancer immunotherapy Research Paper

Pulsed SILAC-based proteomic analysis unveils hypoxia- and serum starvation-induced de novo protein synthesis with PHD finger protein 14 (PHF14) as a hypoxia sensitive epigenetic regulator in cell cycle progression Research Paper

Integrated landscape of copy number variation and RNA expression associated with nodal metastasis in invasive ductal breast carcinoma Research Paper

Correction: Targeting Hsp27/eIF4E interaction with phenazine compound: a promising alternative for castration-resistant prostate cancer treatment Correction

Synergistic effects of inhibiting the MNK-eIF4E and PI3K/AKT/ mTOR pathways on cell migration in MDA-MB-231 cells Research Paper

Increased expression of MNK1b, the spliced isoform of MNK1, predicts poor prognosis and is associated with triple-negative breast cancer Research Paper

Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress Research Paper

Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors Research Paper

Proteomic analysis of chicken embryo fibroblast cells infected with recombinant H5N1 avian influenza viruses with and without NS1 eIF4GI binding domain Research Paper

FLT3-ITD induces expression of Pim kinases through STAT5 to confer resistance to the PI3K/Akt pathway inhibitors on leukemic cells by enhancing the mTORC1/Mcl-1 pathway Research Paper

Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6 Research Paper

Targeting Hsp27/eIF4E interaction with phenazine compound: a promising alternative for castration-resistant prostate cancer treatment Research Paper

Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo Research Paper

Cap-dependent translational control of oncolytic measles virus infection in malignant mesothelioma Research Paper

Targeting EIF4F complex in non-small cell lung cancer cells Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Inhibitory effects of Tomivosertib in acute myeloid leukemia Research Paper

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

Important players in carcinogenesis as potential targets in cancer therapy: an update Review

Inhibitory effects of SEL201 in acute myeloid leukemia Research Paper

Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma Research Paper

A DNA telomerase vaccine for canine cancer immunotherapy Research Paper

Pulsed SILAC-based proteomic analysis unveils hypoxia- and serum starvation-induced de novo protein synthesis with PHD finger protein 14 (PHF14) as a hypoxia sensitive epigenetic regulator in cell cycle progression Research Paper

Integrated landscape of copy number variation and RNA expression associated with nodal metastasis in invasive ductal breast carcinoma Research Paper

Correction: Targeting Hsp27/eIF4E interaction with phenazine compound: a promising alternative for castration-resistant prostate cancer treatment Correction

Synergistic effects of inhibiting the MNK-eIF4E and PI3K/AKT/ mTOR pathways on cell migration in MDA-MB-231 cells Research Paper

Increased expression of MNK1b, the spliced isoform of MNK1, predicts poor prognosis and is associated with triple-negative breast cancer Research Paper

Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress Research Paper

Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors Research Paper

Proteomic analysis of chicken embryo fibroblast cells infected with recombinant H5N1 avian influenza viruses with and without NS1 eIF4GI binding domain Research Paper

FLT3-ITD induces expression of Pim kinases through STAT5 to confer resistance to the PI3K/Akt pathway inhibitors on leukemic cells by enhancing the mTORC1/Mcl-1 pathway Research Paper

Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6 Research Paper

Targeting Hsp27/eIF4E interaction with phenazine compound: a promising alternative for castration-resistant prostate cancer treatment Research Paper

Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo Research Paper

Cap-dependent translational control of oncolytic measles virus infection in malignant mesothelioma Research Paper

Targeting EIF4F complex in non-small cell lung cancer cells Review