The Oncosearch | Oncotarget

COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms Review

Charlotte Kuperwasser, Wafik S. El-Deiry

Published Mar 30, 2026 · Vol. 17, No. 1 · pp. 1-29

Keywords: COVID, vaccine, cancer, infection, lymphoma, leukemia, sarcoma, carcinoma

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Joel Ohana, Uziel Sandler, Benjamin A. Weinberg, Stephen Liu, Yoram Devary

Published Dec 19, 2025 · Vol. 16, No. 1 · pp. 848-857

Keywords: mutant KRAS, Nerofe, ST2 Receptor, tumor immune microenvironment, nuclear immunomodulation

Anti-DNA virus agent cidofovir - loaded green synthesized cerium oxide nanoparticles (Nanoceria): Nucleic acids (DNA and RNA) binding affinity and cytotoxicity effects Research Paper

Nahid Shahabadi, Saba Zendehcheshm, Fatemeh Khademi, Mohammad Mahdavi

Published Oct 23, 2025 · Vol. 16, No. 1 · pp. 768-789

Keywords: CeO₂ NPs, green synthesis, DNA interaction, RNA interaction, cytotoxicity

Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors Review

Helen Qian, Heba Ali, Vivekanudeep Karri, Justin T. Low, David M. Ashley, Amy B. Heimberger, Lucy A. Godley, Adam M. Sonabend, Crismita Dmello

Published Jun 5, 2025 · Vol. 16, No. 1 · pp. 445-453

Keywords: CHEK2, immune checkpoint inhibitors, immunomodulation

UBA1 dysfunction in VEXAS and cancer Research Perspective

Maki Sakuma, Torsten Haferlach, Wencke Walter

Published Aug 27, 2024 · Vol. 15, No. 1 · pp. 644-658

Keywords: VEXAS, MDS, clonal cytopenia, ubiquitin, inflammation

Targeting ABC transporters in PDAC – past, present, or future? Editorial

Cecilia Bergonzini, Elisa Giovannetti, Erik H.J. Danen

Published Jun 14, 2024 · Vol. 15, No. 1 · pp. 403-406

Keywords: PDAC, chemoresistance, ABCB1

Starving cancer cells to enhance DNA damage and immunotherapy response Research Perspective

Aashirwad Shahi, Dawit Kidane

Published Jun 12, 2024 · Vol. 15, No. 1 · pp. 392-399

Keywords: amino acid depletion, DNA damage, DNA repair, Immunotherapy, tumor immunity

GZ17-6.02 kills PDX isolates of uveal melanoma Research Paper

Laurence Booth, Jane L. Roberts, Ivan Spasojevic, Kaitlyn C. Baker, Andrew Poklepovic, Cameron West, John M. Kirkwood, Paul Dent

Published May 9, 2024 · Vol. 15, No. 1 · pp. 328-344

Keywords: autophagy, ER stress, GZ17-6.02, doxorubicin, afatinib, neratinib

Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure Research Paper

Shengliang Zhang, Wafik S. El-Deiry

Published Apr 29, 2024 · Vol. 15, No. 1 · pp. 275-284

Keywords: SARS-COV2 spike, p53, MDM2, chemotherapy, cancer

Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface Research Paper

Takahiro Ohashi, Sayuri Terada, Shinsuke Hiramoto, Yuko Nagata, Hirokazu Suzuki, Hitoshi Miyashita, Tetsuo Sasaki, Yasukatsu Tsukada, Keiko Fukushima

Published Mar 29, 2024 · Vol. 15, No. 1 · pp. 256-274

Keywords: bispecific antibody, Cys1m, IgM, lymphoma, cynomolgus monkey

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer Research Paper

Haven R. Garber, Sreyashi Basu, Sonali Jindal, Zhong He, Khoi Chu, Akshara Singareeka Raghavendra, Clinton Yam, Lumarie Santiago, Beatriz E. Adrada, Padmanee Sharma, Elizabeth A. Mittendorf, Jennifer K. Litton

Published Mar 2, 2024 · Vol. 15, No. 1 · pp. 238-247

Keywords: breast cancer, ER positive, immunotherapy, neoadjuvant chemotherapy, tumor microenvironment

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma Research Perspective

Ashley Del Dosso, Elizabeth Tadevosyan, James R. Berenson

Published Dec 23, 2023 · Vol. 15, No. 1 · pp. 65-75

Keywords: multiple myeloma, ruxolitinib, JAK/STAT, cytokine, clinical trial

Real time ex vivo chemosensitivity assay for pancreatic adenocarcinoma Research Paper

Dae Won Kim, Francisca Beato, Youngchul Kim, Alexandra F. Tassielli, Ruifan Dai, Jason W. Denbo, Pamela J. Hodul, Mokenge P. Malafa, Jason B. Fleming

Published Sep 7, 2023 · Vol. 14, No. 1 · pp. 811-818

Keywords: pancreatic cancer, sensitivity assay, chemotherapy

Targeting GITR in cancer immunotherapy – there is no perfect knowledge Research Perspective

Diwakar Davar, Roberta Zappasodi

Published Jun 12, 2023 · Vol. 14, No. 1 · pp. 614-621

Keywords: cancer, immunotherapy, programmed death-1 (PD-1), cytotoxic T-lymphocyte Antigen-4 (CTLA-4), glucocorticoid-induced TNFR-related protein (GITR)

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells Review

Mikhail V. Blagosklonny

Published Mar 3, 2023 · Vol. 14, No. 1 · pp. 193-206

Keywords: oncology, resistance, cyclotherapy, trilaciclib, rapamycin

Anti-tumor effect of antibody drug conjugate ASP1235 targeting Fms-like tyrosine kinase 3 with venetoclax plus azacitidine in an acute myeloid leukemia xenograft mouse model Research Paper

Hirofumi Tsuzuki, Tatsuya Kawase, Taisuke Nakazawa, Masamichi Mori, Taku Yoshida

Published Dec 13, 2022 · Vol. 13, No. 1 · pp. 1359-1368

Keywords: acute myeloid leukemia (AML), ASP1235, antibody drug conjugate (ADC), venetoclax, azacitidine

CUDC907, a dual phosphoinositide-3 kinase/histone deacetylase inhibitor, promotes apoptosis of NF2 Schwannoma cells Research Paper

Julianne Huegel, Christine T. Dinh, Maria Martinelli, Olena Bracho, Rosa Rosario, Haley Hardin, Michael Estivill, Anthony Griswold, Sakir Gultekin, Xue-Zhong Liu, Cristina Fernandez-Valle

Published Jul 2, 2022 · Vol. 13, No. 1 · pp. 890-904

Keywords: fimepinostat, Schwann cell, vestibular schwanomma, merlin, nerve allograft

Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning Research Paper

Ignacio Durán, Daniel Castellano, Javier Puente, Lidia Martín-Couce, Esther Bello, Urbano Anido, José Manuel Mas, Luis Costa

Published Jan 20, 2022 · Vol. 13, No. 1 · pp. 237-256

Keywords: machine learning, cabozantinib, renal cell carcinoma, tumour microenvironment, systems biology

Circulating low density neutrophils of breast cancer patients are associated with their worse prognosis due to the impairment of T cell responses Research Paper

Diana P. Saraiva, Bruna F. Correia, Rute Salvador, Nídia de Sousa, António Jacinto, Sofia Braga, M. Guadalupe Cabral

Published Nov 15, 2021 · Vol. 12, No. 24 · pp. 2388-2403

Keywords: breast cancer, chemotherapy response, tumor-associated neutrophils, low density neutrophils, biomarker

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper

Ilyas Sahin, Andrew George, Shengliang Zhang, Kelsey E. Huntington, Zehra Ordulu, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 24, 2021 · Vol. 12, No. 21 · pp. 2131-2146

Keywords: cancer immunotherapy, immune checkpoint inhibitors, hyperprogressive disease (HPD), hyperprogression (HP), humanized mouse

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COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms Review

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Anti-DNA virus agent cidofovir - loaded green synthesized cerium oxide nanoparticles (Nanoceria): Nucleic acids (DNA and RNA) binding affinity and cytotoxicity effects Research Paper

Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors Review

UBA1 dysfunction in VEXAS and cancer Research Perspective

Targeting ABC transporters in PDAC – past, present, or future? Editorial

Starving cancer cells to enhance DNA damage and immunotherapy response Research Perspective

GZ17-6.02 kills PDX isolates of uveal melanoma Research Paper

Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure Research Paper

Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface Research Paper

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer Research Paper

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma Research Perspective

Real time ex vivo chemosensitivity assay for pancreatic adenocarcinoma Research Paper

Targeting GITR in cancer immunotherapy – there is no perfect knowledge Research Perspective

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells Review

Anti-tumor effect of antibody drug conjugate ASP1235 targeting Fms-like tyrosine kinase 3 with venetoclax plus azacitidine in an acute myeloid leukemia xenograft mouse model Research Paper

CUDC907, a dual phosphoinositide-3 kinase/histone deacetylase inhibitor, promotes apoptosis of NF2 Schwannoma cells Research Paper

Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning Research Paper

Circulating low density neutrophils of breast cancer patients are associated with their worse prognosis due to the impairment of T cell responses Research Paper

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms Review

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Anti-DNA virus agent cidofovir - loaded green synthesized cerium oxide nanoparticles (Nanoceria): Nucleic acids (DNA and RNA) binding affinity and cytotoxicity effects Research Paper

Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors Review

UBA1 dysfunction in VEXAS and cancer Research Perspective

Targeting ABC transporters in PDAC – past, present, or future? Editorial

Starving cancer cells to enhance DNA damage and immunotherapy response Research Perspective

GZ17-6.02 kills PDX isolates of uveal melanoma Research Paper

Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure Research Paper

Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface Research Paper

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer Research Paper

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma Research Perspective

Real time ex vivo chemosensitivity assay for pancreatic adenocarcinoma Research Paper

Targeting GITR in cancer immunotherapy – there is no perfect knowledge Research Perspective

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells Review

Anti-tumor effect of antibody drug conjugate ASP1235 targeting Fms-like tyrosine kinase 3 with venetoclax plus azacitidine in an acute myeloid leukemia xenograft mouse model Research Paper

CUDC907, a dual phosphoinositide-3 kinase/histone deacetylase inhibitor, promotes apoptosis of NF2 Schwannoma cells Research Paper

Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning Research Paper

Circulating low density neutrophils of breast cancer patients are associated with their worse prognosis due to the impairment of T cell responses Research Paper

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper