The Oncosearch | Oncotarget

Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells Research Paper

Laura Valdez, Benxu Cheng, Daniela Gonzalez, Reanna Rodriguez, Paola Campano, Andrew Tsin, Xiaoqian Fang

Published Apr 22, 2022 · Vol. 13, No. 1 · pp. 642-658

Keywords: glioblastoma, niclosamide, camptothecin, cancer, chemotherapy

Identification of Mubritinib (TAK 165) as an inhibitor of KSHV driven primary effusion lymphoma via disruption of mitochondrial OXPHOS metabolism Research Paper

Abram Calderon, Samantha S. Soldan, Alessandra De Leo, Zhong Deng, Drew M. Frase, Emma M. Anderson, Yue Zhang, Olga Vladimirova, Fang Lu, Jessica C. Leung, Maureen E. Murphy, Paul M. Lieberman

Published Nov 7, 2020 · Vol. 11, No. 46 · pp. 4224-4242

Keywords: KSHV, LANA, high-throughput screen (HTS), primary effusion lymphoma, Mubritinib

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

David King, Xiao Dun Li, Gilberto S. Almeida, Colin Kwok, Polly Gravells, Daniel Harrison, Saoirse Burke, Albert Hallsworth, Yann Jamin, Sally George, Simon P. Robinson, Christopher J. Lord, Evon Poon, Daniel Yeomanson, Louis Chesler, Helen E. Bryant

Published Nov 6, 2019 · Vol. 11, No. 23 · pp. 2141-2159

Keywords: PARP inhibitor, neuroblastoma, MYCN, replication stress, replication fork stalling

Novel clinical indenoisoquinoline topoisomerase I inhibitors: a twist around the camptothecins Editorial

Yves Pommier, Mark Cushman, James H. Doroshow

Published Dec 8, 2018 · Vol. 9, No. 99 · pp. 37286-37288

Camptothecin exhibits topoisomerase1-independent KMT1A suppression and myogenic differentiation in alveolar rhabdomyosarcoma cells Research Paper

David W. Wolff, Min-Hyung Lee, Mathivanan Jothi, Munmun Mal, Fengzhi Li, Asoke K. Mal

Published May 25, 2018 · Vol. 9, No. 40 · pp. 25796-25807

Transcriptional activation of p21Waf1 contributes to suppression of HR by p53 in response to replication arrest induced by camptothecin Research Paper

Larisa Y. Romanova, Frederick Mushinski, Alexander L. Kovalchuk

Published May 22, 2018 · Vol. 9, No. 39 · pp. 25427-25440

Camptothecin induces G₂/M phase arrest through the ATM-Chk2-Cdc25C axis as a result of autophagy-induced cytoprotection: Implications of reactive oxygen species Research Paper

Rajapaksha Gedara Prasad Tharanga Jayasooriya, Matharage Gayani Dilshara, Ilandarage Menu Neelaka Molagoda, Cheol Park, Sang Rul Park, Seungheon Lee, Yung Hyun Choi, Gi-Young Kim

Published Apr 24, 2018 · Vol. 9, No. 31 · pp. 21744-21757

A lethal synergy induced by phellinus linteus and camptothecin11 in colon cancer cells Research Paper

Tianqi Yu, Suthakar Ganapathy, Ling Shen, Bo Peng, Sung-Hoon Kim, Alexandros Makriyannis, Changyan Chen

Published Jan 4, 2018 · Vol. 9, No. 5 · pp. 6308-6319

2,2â€™-Methylenebis (6-tert-butyl 4-methylphenol) enhances the antitumor efficacy of belotecan, a derivative of camptothecin, by inducing autophagy Research Paper

Minsu Jang, Hyunju Kim, Rackhyun Park, Daum Jo, Eun-Ju Lee, Won Keun Oh, Junsoo Park

Published Dec 1, 2017 · Vol. 8, No. 70 · pp. 115068-115078

Sensitizing Ewing sarcoma to chemo- and radiotherapy by inhibition of the DNA-repair enzymes DNA protein kinase (DNA-PK) and poly-ADP-ribose polymerase (PARP) 1/2 Research Paper

Britta Vormoor, Yvonne T. Schlosser, Helen Blair, Abhishek Sharma, Sarah Wilkinson, David R. Newell, Nicola Curtin

Published Sep 28, 2017 · Vol. 8, No. 69 · pp. 113418-113430

Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity Research Paper

Ming-Yue Wu, Sheng-Fang Wang, Cui-Zan Cai, Jie-Qiong Tan, Min Li, Jin-Jian Lu, Xiu-Ping Chen, Yi-Tao Wang, Wei Zheng, Jia-Hong Lu

Published Sep 8, 2017 · Vol. 8, No. 44 · pp. 77673-77684

ELAS1 induces apoptotic death in adenocarcinoma DU145 and squamous-cell carcinoma SAS cancer cells, but not in normal KD cells Research Paper

Toshihiro Uchihashi, Kaori Ota, Yusuke Yabuno, Shouichi Ohno, Kohshiro Fukushima, Yoko Naito, Mikihiko Kogo, Norikazu Yabuta, Hiroshi Nojima

Published Aug 24, 2017 · Vol. 8, No. 49 · pp. 85868-85882

Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation Research Paper

Zuzanna Tracz-Gaszewska, Marta Klimczak, Przemyslaw Biecek, Marcin Herok, Marcin Kosinski, Maciej B. Olszewski, Patrycja CzerwiÅ„ska, Milena Wiech, Maciej Wiznerowicz, Alicja Zylicz, Maciej Zylicz, Bartosz Wawrzynow

Published Jun 30, 2017 · Vol. 8, No. 47 · pp. 82123-82143

Physiologically based pharmacokinetic modeling for predicting irinotecan exposure in human body Research Paper

Yingfang Fan, Najia Mansoor, Tasneem Ahmad, RafeeqAlam Khan, Martin Czejka, Syed Sharib, Dong-Hua Yang, Mansoor Ahmed

Published Jun 6, 2017 · Vol. 8, No. 29 · pp. 48178-48185

The palmitoylation of the N-terminal extracellular Cys37 mediates the nuclear translocation of VPAC1 contributing to its anti-apoptotic activity Research Paper

Rongjie Yu, Hongyu Liu, Xinhe Peng, Yue Cui, Suqin Song, Like Wang, Huahua Zhang, An Hong, Tianhong Zhou

Published Apr 27, 2017 · Vol. 8, No. 26 · pp. 42728-42741

Integration of phytochemicals and phytotherapy into cancer precision medicine Review

Thomas Efferth, Mohamed E.M. Saeed, Elhaj Mirghani, Awadh Alim, Zahir Yassin, Elfatih Saeed, Hassan E. Khalid, Salah Daak

Published Apr 27, 2017 · Vol. 8, No. 30 · pp. 50284-50304

Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway Research Paper

Koji Ando, Ankur K. Shah, Vibhu Sachdev, Benjamin P. Kleinstiver, Julian Taylor-Parker, Moira M. Welch, Yiheng Hu, Ravi Salgia, Forest M. White, Jeffrey D. Parvin, Al Ozonoff, Lucia E. Rameh, J. Keith Joung, Ajit K. Bharti

Published Mar 18, 2017 · Vol. 8, No. 27 · pp. 43733-43751

Nanocrystals of a new camptothecin derivative WCN-21 enhance its solubility and efficacy Research Paper

Jia You, Yuyuan Chen, Zubaeda M. Mohamed Alsayeh, Xingyu Shen, Chun Li, Pengxuan Zhao, Fei Chen, Yingqian Liu, Chuanrui Xu

Published Mar 13, 2017 · Vol. 8, No. 18 · pp. 29808-29822

VHL missense mutations in the p53 binding domain show different effects on p53 signaling and HIFα degradation in clear cell renal cell carcinoma Research Paper

Caroline Fanja Razafinjatovo, Daniel Stiehl, Eva Deininger, Markus Rechsteiner, Holger Moch, Peter Schraml

Published Dec 30, 2016 · Vol. 8, No. 6 · pp. 10199-10212

Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma Research Paper

Boris Redko, Helena Tuchinsky, Tamar Segal, Dror Tobi, Galia Luboshits, Osnat Ashur-Fabian, Albert Pinhasov, Gabi Gerlitz, Gary Gellerman

Published Oct 19, 2016 · Vol. 8, No. 1 · pp. 757-768

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Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells Research Paper

Identification of Mubritinib (TAK 165) as an inhibitor of KSHV driven primary effusion lymphoma via disruption of mitochondrial OXPHOS metabolism Research Paper

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

Novel clinical indenoisoquinoline topoisomerase I inhibitors: a twist around the camptothecins Editorial

Camptothecin exhibits topoisomerase1-independent KMT1A suppression and myogenic differentiation in alveolar rhabdomyosarcoma cells Research Paper

Transcriptional activation of p21Waf1 contributes to suppression of HR by p53 in response to replication arrest induced by camptothecin Research Paper

Camptothecin induces G₂/M phase arrest through the ATM-Chk2-Cdc25C axis as a result of autophagy-induced cytoprotection: Implications of reactive oxygen species Research Paper

A lethal synergy induced by phellinus linteus and camptothecin11 in colon cancer cells Research Paper

2,2â€™-Methylenebis (6-tert-butyl 4-methylphenol) enhances the antitumor efficacy of belotecan, a derivative of camptothecin, by inducing autophagy Research Paper

Sensitizing Ewing sarcoma to chemo- and radiotherapy by inhibition of the DNA-repair enzymes DNA protein kinase (DNA-PK) and poly-ADP-ribose polymerase (PARP) 1/2 Research Paper

Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity Research Paper

ELAS1 induces apoptotic death in adenocarcinoma DU145 and squamous-cell carcinoma SAS cancer cells, but not in normal KD cells Research Paper

Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation Research Paper

Physiologically based pharmacokinetic modeling for predicting irinotecan exposure in human body Research Paper

The palmitoylation of the N-terminal extracellular Cys37 mediates the nuclear translocation of VPAC1 contributing to its anti-apoptotic activity Research Paper

Integration of phytochemicals and phytotherapy into cancer precision medicine Review

Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway Research Paper

Nanocrystals of a new camptothecin derivative WCN-21 enhance its solubility and efficacy Research Paper

VHL missense mutations in the p53 binding domain show different effects on p53 signaling and HIFα degradation in clear cell renal cell carcinoma Research Paper

Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells Research Paper

Identification of Mubritinib (TAK 165) as an inhibitor of KSHV driven primary effusion lymphoma via disruption of mitochondrial OXPHOS metabolism Research Paper

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

Novel clinical indenoisoquinoline topoisomerase I inhibitors: a twist around the camptothecins Editorial

Camptothecin exhibits topoisomerase1-independent KMT1A suppression and myogenic differentiation in alveolar rhabdomyosarcoma cells Research Paper

Transcriptional activation of p21Waf1 contributes to suppression of HR by p53 in response to replication arrest induced by camptothecin Research Paper

Camptothecin induces G2/M phase arrest through the ATM-Chk2-Cdc25C axis as a result of autophagy-induced cytoprotection: Implications of reactive oxygen species Research Paper

A lethal synergy induced by phellinus linteus and camptothecin11 in colon cancer cells Research Paper

2,2â€™-Methylenebis (6-tert-butyl 4-methylphenol) enhances the antitumor efficacy of belotecan, a derivative of camptothecin, by inducing autophagy Research Paper

Sensitizing Ewing sarcoma to chemo- and radiotherapy by inhibition of the DNA-repair enzymes DNA protein kinase (DNA-PK) and poly-ADP-ribose polymerase (PARP) 1/2 Research Paper

Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity Research Paper

ELAS1 induces apoptotic death in adenocarcinoma DU145 and squamous-cell carcinoma SAS cancer cells, but not in normal KD cells Research Paper

Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation Research Paper

Physiologically based pharmacokinetic modeling for predicting irinotecan exposure in human body Research Paper

The palmitoylation of the N-terminal extracellular Cys37 mediates the nuclear translocation of VPAC1 contributing to its anti-apoptotic activity Research Paper

Integration of phytochemicals and phytotherapy into cancer precision medicine Review

Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway Research Paper

Nanocrystals of a new camptothecin derivative WCN-21 enhance its solubility and efficacy Research Paper

VHL missense mutations in the p53 binding domain show different effects on p53 signaling and HIFα degradation in clear cell renal cell carcinoma Research Paper

Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma Research Paper

Camptothecin induces G₂/M phase arrest through the ATM-Chk2-Cdc25C axis as a result of autophagy-induced cytoprotection: Implications of reactive oxygen species Research Paper