Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper
Keywords: mutant KRAS, Nerofe, ST2 Receptor, tumor immune microenvironment, nuclear immunomodulation
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LRIG1-3 in gliomas: LRIG1 protein expression decreased in higher grade gliomas Research Paper
Keywords: glioma, glioblastoma, LRIG1, LRIG2, LRIG3
PCAIs stimulate MAPK, PI3K/AKT pathways and ROS-Mediated apoptosis in aromatase inhibitor-resistant breast cancer cells while disrupting actin filaments and focal adhesion Research Paper
Keywords: PCAIs, ROS, MAPK, PI3K/AKT, LTLT-Ca cells
Case Report WIN-MTB-2023001 WIN International Molecular Tumor Board A 62-year-old male with metastatic colorectal cancer with 5 prior lines of treatment Precision Oncology
Keywords: cancer, precision oncology, molecular tumor board, colorectal carcinoma, cancer management
Case Report WIN-MTB-2023001 WIN International Molecular Tumor Board A 62-year-old male with metastatic colorectal cancer with 5 prior lines of treatment Case Report
Keywords: cancer, precision oncology, molecular tumor board, colorectal carcinoma, cancer management
Durable complete response in leptomeningeal disease of EGFR mutated non-small cell lung cancer to amivantamab, an EGFR-MET receptor bispecific antibody, after progressing on osimertinib Research Paper
Keywords: amivantamab, monotherapy, rare EGFR mutation, NSCLC, leptomeningeal disease
Correction: Activation of PI3K/Akt/mTOR signaling in the tumor stroma drives endocrine therapy-dependent breast tumor regression Correction
Targeting PCNA/AR interaction inhibits AR-mediated signaling in castration resistant prostate cancer cells Research Paper
Keywords: PCNA, androgen receptor, PCNA inhibitors, AR splicing variants, CRPC
Correction: Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Correction
NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma Research Paper
Keywords: myeloma, NSD2, t(4;14), CD38, plasma cell
Correction: Catalytic inhibitors of DNA topoisomerase II suppress the androgen receptor signaling and prostate cancer progression Correction
Robust p53 phenotypes and prospective downstream targets in telomerase-immortalized human cells Research Paper
Keywords: p53, ionizing radiation, immortalized cells, ALDH3A1, NECTIN4
Evolving concepts in HER2-low breast cancer: Genomic insights, definitions, and treatment paradigms Review
Keywords: breast cancer, HER2-low, genomics
Advancements in cell-penetrating monoclonal antibody treatment News
Keywords: monoclonal anti-bodies, cell penetration, nucleic acid delivery, 3E10
Correction: The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation Correction
B7-H4: A potential therapeutic target in adenoid cystic carcinoma Editorial
Keywords: salivary gland cancer, adenoid cystic carcinoma, rare cancer, b7-h4, antibody drug conjugate
Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition Research Paper
Keywords: 3E10, cell penetration, nucleic acid binding, nucleic acid delivery, RAD51
A nanobody against the V-ATPase c subunit inhibits metastasis of 4T1-12B breast tumor cells to lung in mice Research Paper
Keywords: vacuolar ATPase, breast cancer, invasion, tumor metastasis, tumor growth
Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival Research Paper
Keywords: RNLS, melanoma, T-cell receptor CDR3s, chemical complementarity
Targeting WNT5B and WNT10B in osteosarcoma Review
Keywords: WNT5B, WNT10B, WNT signaling, osteosarcoma