The Oncosearch | Oncotarget

Reassessing the role of high dose cytarabine and mitoxantrone in relapsed/refractory acute myeloid leukemia Research Paper

Jonathan Canaani, Meital Nagar, Gabriel Heering, Chen Gefen, Ronit Yerushalmi, Noga Shem-Tov, Yulia Volchek, Drorit Merkel, Abraham Avigdor, Avichai Shimoni, Ninette Amariglio, Gidi Rechavi, Arnon Nagler

Published May 24, 2020 · Vol. 11, No. 23 · pp. 2233-2245

Keywords: acute myeloid leukemia, FLT3-ITD, next-generation sequencing

Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2 Research Paper

Leanne Milton-Harris, Mark Jeeves, Sarah A. Walker, Simon E. Ward, Erika J. Mancini

Published Apr 22, 2020 · Vol. 11, No. 19 · pp. 1737-1748

Keywords: protein-protein interaction, leukaemia, T-ALL, drug discovery, LMO2

Zebrafish B cell acute lymphoblastic leukemia: new findings in an old model Research Perspective

Gilseung Park, Jessica Burroughs-Garcia, Clay A. Foster, Ameera Hasan, Chiara Borga, J. Kimble Frazer

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1292-1305

Keywords: acute lymphoblastic leukemia, ALL, zebrafish, lymphocyte, MYC

Acute promyelocytic leukemia (APL): a review of the literature Review

Joaquin J. Jimenez, Ravinder S. Chale, Andrea C. Abad, Andrew V. Schally

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 992-1003

Keywords: promyelocytic leukemia, arsenic trioxide, retinoic acid, resistance

Quizartinib, a selective FLT3 inhibitor, maintains antileukemic activity in preclinical models of RAS-mediated midostaurin-resistant acute myeloid leukemia cells Research Paper

Tomoya Aikawa, Noriko Togashi, Koichi Iwanaga, Hiroyuki Okada, Yumi Nishiya, Shinichi Inoue, Mark J. Levis, Takeshi Isoyama

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 943-955

Keywords: relapsed/refractory AML, FLT3 inhibitors, quizartinib, AC886, midostaurin resistance

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

Brandi L. Carofino, Kayla M. Dinshaw, Pui Yan Ho, Christophe Cataisson, Aleksandra M. Michalowski, Andrew Ryscavage, Addie Alkhas, Nathan W. Wong, Vishal Koparde, Stuart H. Yuspa

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7251-7275

Keywords: in situ hybridization, single-cell RNA-sequencing, stroma, miRNA, immune infiltration

Inhibitory effects of SEL201 in acute myeloid leukemia Research Paper

Ewa M. Kosciuczuk, Aroop K. Kar, Gavin T. Blyth, Mariafausta Fischietti, Sameem Abedin, Alain A. Mina, Rebekah Siliezar, Tomasz Rzymski, Krzysztof Brzozka, Elizabeth A. Eklund, Elspeth M. Beauchamp, Frank Eckerdt, Diana Saleiro, Leonidas C. Platanias

Published Dec 24, 2019 · Vol. 10, No. 67 · pp. 7112-7121

Keywords: acute myeloid leukemia, MNK, eIF4E, kinase inhibitor, SEL201

Erratum: PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors Errata

Amanda M. Smith, Christine R.C. Zhang, Alexandre S. Cristino, John P. Grady, J. Lynn Fink, Andrew S. Moore

Published Dec 18, 2019 · Vol. 11, No. 3 · pp. 305-305

Flow cytometric significance of cellular alkaline phosphatase activity in acute myeloid leukemia Research Paper

Laura G. Rico, Jordi Juncà, Michael D. Ward, Jolene A. Bradford, Jordi Petriz

Published Dec 10, 2019 · Vol. 10, No. 65 · pp. 6969-6980

Keywords: alkaline phosphatase, acute myeloid leukemia, stem cells, leukemic stem cells, CD34

Correction: Lactate promotes PGE2 synthesis and gluconeogenesis in monocytes to benefit the growth of inflammation-associated colorectal tumor Correction

Libin Wei, Yuxin Zhou, Jing Yao, Chen Qiao, Ting Ni, Ruichen Guo, Qinglong Guo, Na Lu

Published Nov 20, 2019

Targeted enhancement of the therapeutic window of L19-TNF by transient and selective inhibition of RIPK1-signaling cascade Research Paper

Sheila Dakhel, Tiziano Ongaro, Baptiste Gouyou, Mattia Matasci, Alessandra Villa, Dario Neri, Samuele Cazzamalli

Published Nov 19, 2019 · Vol. 10, No. 62 · pp. 6678-6690

Keywords: tumor targeting, antibody-cytokine fusions, targeted-tumor necrosis factor, EDB-fibronectin, intracellular RIPK1-inhibitors

Correction: The combination effect of homoharringtonine and ibrutinib on FLT3-ITD mutant acute myeloid leukemia Correction

Xia Li, Xiufeng Yin, Huafeng Wang, Jiansong Huang, Mengxia Yu, Zhixin Ma, Chenying Li, Yile Zhou, Xiao Yan, ShuJuan Huang, Jie Jin

Published Oct 29, 2019 · Vol. 10, No. 61 · pp. 6641-6642

Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts Research Paper

Emily Marie Mangialardi, Keyue Chen, Brittany Salmon, Jean Vacher, Leonardo Salmena

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6378-6390

Keywords: Inpp4b, MEF, RAS, E1A, SV40-T-Large

Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells Research Paper

Tatsuya Kawase, Taisuke Nakazawa, Tomohiro Eguchi, Hirofumi Tsuzuki, Yoko Ueno, Yasushi Amano, Tomoyuki Suzuki, Masamichi Mori, Taku Yoshida

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6111-6123

Keywords: FLT3, FL, FLT3 inhibitor, gilteritinib, antitumor activity

Adoptive cellular immunotherapy for refractory childhood cancers: a single center experience Research Paper

Michael Merker, Michael Torsten Meister, Annekathrin Heinze, Andrea Jarisch, Jan Sörensen, Sabine Huenecke, Melanie Bremm, Claudia Cappel, Thomas Klingebiel, Peter Bader, Eva Rettinger

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6138-6151

Keywords: adoptive cellular immunotherapy, allogeneic, solid tumors, childhood, HSCT

PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors Research Paper

Amanda M. Smith, Christine R.C. Zhang, Alexandre S. Cristino, John P. Grady, J. Lynn Fink, Andrew S. Moore

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5755-5767

Keywords: myeloid leukemia, therapy, drug resistance, hematological malignancies, gene mutation

Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

Michelle M. Williams, David L. Elion, Bushra Rahman, Donna J. Hicks, Violeta Sanchez, Rebecca S. Cook

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5389-5402

Keywords: Mcl-1, ABT-263 resistance, mTORC1 signaling, luminal breast cancers

Correction: NKp30 expression is a prognostic immune biomarker for stratification of patients with intermediate-risk acute myeloid leukemia Correction

Anne-Sophie Chretien, Cyril Fauriat, Florence Orlanducci, Jerome Rey, Gaelle Bouvier Borg, Emmanuel Gautherot, Samuel Granjeaud, Clemence Demerle, Jean-François Hamel, Adelheid Cerwenka, Elke Pogge von Strandmann, Norbert Ifrah, Catherine Lacombe, Pascale Cornillet-Lefebvre, Jacques Delaunay, Antoine Toubert, Christine Arnoulet, Norbert Vey, Daniel Olive

Published Sep 4, 2019 · Vol. 10, No. 52 · pp. 5493-5493

Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells Research Paper

El-Habib Dakir, Faustino Mollinedo

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5313-5331

Keywords: miRNA, miR-125a-5p, miR-17-92, neutrophil differentiation, human

Drivers of topoisomerase II poisoning mimic and complement cytotoxicity in AML cells Research Paper

Piyush More, Ute Goedtel-Armbrust, Viral Shah, Marianne Mathaes, Thomas Kindler, Miguel A. Andrade-Navarro, Leszek Wojnowski

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5298-5312

Keywords: topoisomerase II poisons, DNA damage, gene expression, combination therapy, cancer essentiality

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Reassessing the role of high dose cytarabine and mitoxantrone in relapsed/refractory acute myeloid leukemia Research Paper

Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2 Research Paper

Zebrafish B cell acute lymphoblastic leukemia: new findings in an old model Research Perspective

Acute promyelocytic leukemia (APL): a review of the literature Review

Quizartinib, a selective FLT3 inhibitor, maintains antileukemic activity in preclinical models of RAS-mediated midostaurin-resistant acute myeloid leukemia cells Research Paper

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

Inhibitory effects of SEL201 in acute myeloid leukemia Research Paper

Erratum: PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors Errata

Flow cytometric significance of cellular alkaline phosphatase activity in acute myeloid leukemia Research Paper

Correction: Lactate promotes PGE2 synthesis and gluconeogenesis in monocytes to benefit the growth of inflammation-associated colorectal tumor Correction

Targeted enhancement of the therapeutic window of L19-TNF by transient and selective inhibition of RIPK1-signaling cascade Research Paper

Correction: The combination effect of homoharringtonine and ibrutinib on FLT3-ITD mutant acute myeloid leukemia Correction

Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts Research Paper

Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells Research Paper

Adoptive cellular immunotherapy for refractory childhood cancers: a single center experience Research Paper

PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors Research Paper

Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

Correction: NKp30 expression is a prognostic immune biomarker for stratification of patients with intermediate-risk acute myeloid leukemia Correction

Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells Research Paper

Drivers of topoisomerase II poisoning mimic and complement cytotoxicity in AML cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Reassessing the role of high dose cytarabine and mitoxantrone in relapsed/refractory acute myeloid leukemia Research Paper

Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2 Research Paper

Zebrafish B cell acute lymphoblastic leukemia: new findings in an old model Research Perspective

Acute promyelocytic leukemia (APL): a review of the literature Review

Quizartinib, a selective FLT3 inhibitor, maintains antileukemic activity in preclinical models of RAS-mediated midostaurin-resistant acute myeloid leukemia cells Research Paper

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

Inhibitory effects of SEL201 in acute myeloid leukemia Research Paper

Erratum: PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors Errata

Flow cytometric significance of cellular alkaline phosphatase activity in acute myeloid leukemia Research Paper

Correction: Lactate promotes PGE2 synthesis and gluconeogenesis in monocytes to benefit the growth of inflammation-associated colorectal tumor Correction

Targeted enhancement of the therapeutic window of L19-TNF by transient and selective inhibition of RIPK1-signaling cascade Research Paper

Correction: The combination effect of homoharringtonine and ibrutinib on FLT3-ITD mutant acute myeloid leukemia Correction

Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts Research Paper

Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells Research Paper

Adoptive cellular immunotherapy for refractory childhood cancers: a single center experience Research Paper

PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors Research Paper

Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

Correction: NKp30 expression is a prognostic immune biomarker for stratification of patients with intermediate-risk acute myeloid leukemia Correction

Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells Research Paper

Drivers of topoisomerase II poisoning mimic and complement cytotoxicity in AML cells Research Paper