The Oncosearch | Oncotarget

Efficacy and safety of PD-1/ PD-L1 inhibitors as adjuvants in the treatment of patients with solid cancers: A systematic review and meta-analysis of randomized controlled trials Research Paper

Maryam Aleid, Fatimah Aleid, Daniah Allbdi, Ahmad Rchdeih, Dhai Almuteri, Abdulelah Almesned, Samaa Alotab, Yumna AlMishary, Galia Alsamman, Atlal Abusanad

Published Apr 1, 2026 · Vol. 17, No. 1 · pp. 120-135

Keywords: PD-1, PD-L1, adjuvant immunotherapy, cancer, solid tumor

Case Report WIN-MTB-2023001 WIN International Molecular Tumor Board A 62-year-old male with metastatic colorectal cancer with 5 prior lines of treatment Precision Oncology

Alberto Hernando-Calvo, Razelle Kurzrock, Nadia Saoudi Gonzalez, Shai Magidi, Catherine Bresson, Fanny Wunder, Giulia Pretelli, Agatha Martin Casado, Wafik S. El-Deiry

Published Jun 9, 2025 · Vol. 16, No. 1 · pp. 456-466

Keywords: cancer, precision oncology, molecular tumor board, colorectal carcinoma, cancer management

Case Report WIN-MTB-2023001 WIN International Molecular Tumor Board A 62-year-old male with metastatic colorectal cancer with 5 prior lines of treatment Case Report

Alberto Hernando-Calvo, Razelle Kurzrock, Nadia Saoudi Gonzalez, Shai Magidi, Catherine Bresson, Fanny Wunder, Giulia Pretelli, Agatha Martin Casado, Wafik S. El-Deiry

Published Jun 9, 2025

Keywords: cancer, precision oncology, molecular tumor board, colorectal carcinoma, cancer management

Association between two single nucleotide polymorphisms of the Prostaglandin-Endoperoxide Synthase 1 and 2 genes and cell proliferative prostatic diseases in Lebanon Research Paper

Brock J. Sheehan, Bryson Edwards, Ivanna Soto Medrano, Mohammed A. El-Saidi, Wissam R. Zaidan, Asmahan A. El-Ezzi, Ruhul H. Kuddus

Published Mar 31, 2025 · Vol. 16, No. 1 · pp. 262-272

Keywords: PTGS1 and PTGS2 genes, COX-1 and COX-2 isozymes, single nucleotide polymorphism association study, prostate cancer, benign prostate hyperplasia (BPH)

A nanobody against the V-ATPase c subunit inhibits metastasis of 4T1-12B breast tumor cells to lung in mice Research Paper

Zhen Li, Mohammed A. Alshagawi, Rebecca A. Oot, Mariam K. Alamoudi, Kevin Su, Wenhui Li, Michael P. Collins, Stephan Wilkens, Michael Forgac

Published Aug 5, 2024 · Vol. 15, No. 1 · pp. 575-587

Keywords: vacuolar ATPase, breast cancer, invasion, tumor metastasis, tumor growth

Investigating the prevalence of pathogenic variants in Saudi Arabian patients with familial cancer using a multigene next generation sequencing panel Research Paper

Musa AlHarbi, Nahla Ali Mobark, Wael Abdel Rahman AlJabarat, Hadeel ElBardis, Ebtehal AlSolme, Abdullah Bany Hamdan, Ali H. AlFakeeh, Fatimah AlMushawah, Fawz AlHarthi, Abdullah A. AlSharm, Ali Abdullah O. Balbaid, Naji AlJohani, Alicia Y. Zhou, Heather A. Robinson, Saleh A. Alqahtani, Malak Abedalthagafi

Published Jun 7, 2023 · Vol. 14, No. 1 · pp. 580-594

Keywords: cancer, hereditary cancer syndrome, genetic counseling, NGS, cancer screening

Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression Research Paper

Mohammad Salman Akhtar, Naseem Akhter, Arshi Talat, Raed A. Alharbi, Abdulmajeed A.A. Sindi, Faisal Klufah, Hanan E. Alyahyawi, Abdulmohsen Alruwetei, Abrar Ahmad, Mazin A. Zamzami, SVS Deo, Syed Akhtar Husain, Osama A. Badi, Mohammad Jahir Khan

Published May 16, 2023 · Vol. 14, No. 1 · pp. 528-541

Keywords: BORIS, breast cancer, mutation, transcription factor, PCR-SSCP

Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines Research Paper

Nada Tawfeeq, Jassy Mary S. Lazarte, Yonghao Jin, Matthew D. Gregory, Nazarius S. Lamango

Published Mar 15, 2023 · Vol. 14, No. 1 · pp. 243-257

Keywords: PCAIs, G-proteins, KRAS, RHOA, RAC1

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper

Duna H. Barakeh, Rasha Aljelaify, Yara Bashawri, Amal Almutairi, Fatimah Alqubaishi, Mohammed Alnamnakani, Latifa Almubarak, Abdulrahman Al Naeem, Fatema Almushawah, May Alrashed, Malak Abedalthagafi

Published Feb 27, 2021 · Vol. 12, No. 7 · pp. 686-697

Keywords: breast cancer, PIK3CA, BCa, Saudi Arabia, BRCA

Cancer stem cells and macrophages: molecular connections and future perspectives against cancer Review

Beatrice Aramini, Valentina Masciale, Giulia Grisendi, Federico Banchelli, Roberto D’Amico, Antonino Maiorana, Uliano Morandi, Massimo Dominici, Khawaja Husnain Haider

Published Jan 27, 2021 · Vol. 12, No. 3 · pp. 230-250

Keywords: cancer stem cells, macrophages, future perspectives, cancer, target treatments

Evidence for context-dependent functions of KDM5B in prostate development and prostate cancer Research Paper

Bigang Liu, Rahul Kumar, Hseuh-Ping Chao, Rashid Mehmood, Yibing Ji, Amanda Tracz, Dean G. Tang

Published Nov 10, 2020 · Vol. 11, No. 46 · pp. 4243-4252

Keywords: KDM5B, prostate cancer, prostate development, hyperplasia, epigenetics

Targeting 14-3-3ε-CDC25A interactions to trigger apoptotic cell death in skin cancer Research Paper

Thomas R. Holmes, Jenan Al-Matouq, Matti Holmes, Lauren Nicola, Justin C. Rudd, Sándor Lovas, Laura A. Hansen

Published Jul 30, 2020 · Vol. 11, No. 35 · pp. 3267-3278

Keywords: skin cancer, squamous cell carcinoma, CDC25A, 14-3-3ε, apoptosis

Caveolin-1 Y14 phosphorylation suppresses tumor growth while promoting invasion Research Paper

Bharat Joshi, Judy Pawling, Jay Shankar, Karina Pacholczyk, Yohan Kim, Wynn Tran, Fanrui Meng, Anas M. Abdel Rahman, Leonard J. Foster, Hon S. Leong, James W. Dennis, Ivan R. Nabi

Published Nov 19, 2019 · Vol. 10, No. 62 · pp. 6668-6677

Keywords: caveolin-1, TP53, tumor suppressor, tumor cell metabolism, invadopodia

Mutational profile and genotype/phenotype correlation of non-familial pheochromocytoma and paraganglioma Research Paper

Shatha Albattal, Meshael Alswailem, Yosra Moria, Hindi Al-Hindi, Majed Dasouki, Mohamed Abouelhoda, Hala Aba Alkhail, Entissar Alsuhaibani, Ali S. Alzahrani

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5919-5931

Keywords: pheochromocytoma, paraganglioma, mutations, NGS, SDHB

New insights into the genomic landscape of meningiomas identified FGFR3 in a subset of patients with favorable prognoses Research Paper

Aysha AlSahlawi, Rasha Aljelaify, Amna Magrashi, Mariam AlSaeed, Amal Almutairi, Fatimah Alqubaishi, Abdulellah Alturkistani, Abdullah AlObaid, Mohamed Abouelhoda, Latifa AlMubarak, Nada AlTassan, Malak Abedalthagafi

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5549-5559

Keywords: meningioma, FGFR3, NGS, genomics, CNS

Polyphenols enhance the activity of alkylating agents in leukaemia cell lines Research Paper

Amani A. Mahbub, Christine L. Le Maitre, Sarah Haywood-Small, Neil A. Cross, Nicola Jordan-Mahy

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4570-4586

Keywords: leukaemia, cisplatin, cyclophosphamide, chlorambucil, polyphenols

GPCR-mediated PI3K pathway mutations in pediatric and adult thyroid cancer Research Paper

Avaniyapuram Kannan Murugan, Ebtesam Qasem, Hindi Al-Hindi, Ali S. Alzahrani

Published Jun 25, 2019 · Vol. 10, No. 41 · pp. 4107-4124

Keywords: thyroid cancer, mutations, PTEN, oncogene, PIK3CA

Overexpression of PARP is an independent prognostic marker for poor survival in Middle Eastern breast cancer and its inhibition can be enhanced with embelin co-treatment Research Paper

Abdul Khalid Siraj, Poyil Pratheeshkumar, Sandeep Kumar Parvathareddy, Sasidharan Padmaja Divya, Fouad Al-Dayel, Asma Tulbah, Dahish Ajarim, Khawla S. Al-Kuraya

Published Dec 18, 2018 · Vol. 9, No. 99 · pp. 37319-37332

Constitutional mismatch repair-deficiency: current problems and emerging therapeutic strategies Review

Malak Abedalthagafi

Published Oct 23, 2018 · Vol. 9, No. 83 · pp. 35458-35469

ATR suppresses the pro-tumorigenic functions of breast stromal fibroblasts Research Paper

Mysoon M. Al-Ansari, Abdelilah Aboussekhra

Published Oct 5, 2018 · Vol. 9, No. 78 · pp. 34681-34690

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Efficacy and safety of PD-1/ PD-L1 inhibitors as adjuvants in the treatment of patients with solid cancers: A systematic review and meta-analysis of randomized controlled trials Research Paper

Case Report WIN-MTB-2023001 WIN International Molecular Tumor Board A 62-year-old male with metastatic colorectal cancer with 5 prior lines of treatment Precision Oncology

Case Report WIN-MTB-2023001 WIN International Molecular Tumor Board A 62-year-old male with metastatic colorectal cancer with 5 prior lines of treatment Case Report

Association between two single nucleotide polymorphisms of the Prostaglandin-Endoperoxide Synthase 1 and 2 genes and cell proliferative prostatic diseases in Lebanon Research Paper

A nanobody against the V-ATPase c subunit inhibits metastasis of 4T1-12B breast tumor cells to lung in mice Research Paper

Investigating the prevalence of pathogenic variants in Saudi Arabian patients with familial cancer using a multigene next generation sequencing panel Research Paper

Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression Research Paper

Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines Research Paper

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper

Cancer stem cells and macrophages: molecular connections and future perspectives against cancer Review

Evidence for context-dependent functions of KDM5B in prostate development and prostate cancer Research Paper

Targeting 14-3-3ε-CDC25A interactions to trigger apoptotic cell death in skin cancer Research Paper

Caveolin-1 Y14 phosphorylation suppresses tumor growth while promoting invasion Research Paper

Mutational profile and genotype/phenotype correlation of non-familial pheochromocytoma and paraganglioma Research Paper

New insights into the genomic landscape of meningiomas identified FGFR3 in a subset of patients with favorable prognoses Research Paper

Polyphenols enhance the activity of alkylating agents in leukaemia cell lines Research Paper

GPCR-mediated PI3K pathway mutations in pediatric and adult thyroid cancer Research Paper

Overexpression of PARP is an independent prognostic marker for poor survival in Middle Eastern breast cancer and its inhibition can be enhanced with embelin co-treatment Research Paper

Constitutional mismatch repair-deficiency: current problems and emerging therapeutic strategies Review

ATR suppresses the pro-tumorigenic functions of breast stromal fibroblasts Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Efficacy and safety of PD-1/ PD-L1 inhibitors as adjuvants in the treatment of patients with solid cancers: A systematic review and meta-analysis of randomized controlled trials Research Paper

Case Report WIN-MTB-2023001 WIN International Molecular Tumor Board A 62-year-old male with metastatic colorectal cancer with 5 prior lines of treatment Precision Oncology

Case Report WIN-MTB-2023001 WIN International Molecular Tumor Board A 62-year-old male with metastatic colorectal cancer with 5 prior lines of treatment Case Report

Association between two single nucleotide polymorphisms of the Prostaglandin-Endoperoxide Synthase 1 and 2 genes and cell proliferative prostatic diseases in Lebanon Research Paper

A nanobody against the V-ATPase c subunit inhibits metastasis of 4T1-12B breast tumor cells to lung in mice Research Paper

Investigating the prevalence of pathogenic variants in Saudi Arabian patients with familial cancer using a multigene next generation sequencing panel Research Paper

Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression Research Paper

Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines Research Paper

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper

Cancer stem cells and macrophages: molecular connections and future perspectives against cancer Review

Evidence for context-dependent functions of KDM5B in prostate development and prostate cancer Research Paper

Targeting 14-3-3ε-CDC25A interactions to trigger apoptotic cell death in skin cancer Research Paper

Caveolin-1 Y14 phosphorylation suppresses tumor growth while promoting invasion Research Paper

Mutational profile and genotype/phenotype correlation of non-familial pheochromocytoma and paraganglioma Research Paper

New insights into the genomic landscape of meningiomas identified FGFR3 in a subset of patients with favorable prognoses Research Paper

Polyphenols enhance the activity of alkylating agents in leukaemia cell lines Research Paper

GPCR-mediated PI3K pathway mutations in pediatric and adult thyroid cancer Research Paper

Overexpression of PARP is an independent prognostic marker for poor survival in Middle Eastern breast cancer and its inhibition can be enhanced with embelin co-treatment Research Paper

Constitutional mismatch repair-deficiency: current problems and emerging therapeutic strategies Review

ATR suppresses the pro-tumorigenic functions of breast stromal fibroblasts Research Paper