The Oncosearch | Oncotarget

Gene regulatory network and signalling pathway rewiring: How blood cancer cells shift their shapes to evade drug treatment Editorial

Constanze Bonifer, Peter N. Cockerill

Published Oct 8, 2024 · Vol. 15, No. 1 · pp. 714-716

Keywords: acute myeloid leukaemia, gene regulatory networks, aberrant growth factor signaling, transcription, RUNX1/AP-1 axis

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Pascale Tomasini, Fabrice Barlesi, Sophie Gilles, Isabelle Nanni-Metellus, Riccardo Soffietti, Emilie Denicolai, Eric Pellegrino, Emilie Bialecki, L’Houcine Ouafik, Philippe Metellus

Published Nov 27, 2020 · Vol. 11, No. 50 · pp. 4648-4654

Keywords: lung cancer, brain metastasis, whole exome sequencing, comparison, mutations

Cytogenetic and molecular landscape and its potential clinical significance in Hispanic CMML patients from Puerto Rico Research Paper

Zeju Jiang, Xinlai Sun, Zhao Wu, Albert Alhatem, Ruifang Zheng, Dongfang Liu, Yaqun Wang, Dibyendu Kumar, Changqing Xia, Bei You, He Wang, Chen Liu, Jie-Gen Jiang

Published Nov 17, 2020 · Vol. 11, No. 47 · pp. 4411-4420

Keywords: chronic myelomonocytic leukemia, Hispanic, cytogenetic abnormality, gene mutation

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

Joshua T. Rose, Eliana Moskovitz, Joseph R. Boyd, Jonathan A. Gordon, Nicole A. Bouffard, Andrew J. Fritz, Anuradha Illendula, John H. Bushweller, Jane B. Lian, Janet L. Stein, Sayyed K. Zaidi, Gary S. Stein

Published May 30, 2020 · Vol. 11, No. 26 · pp. 2512-2530

Keywords: mammary epithelial phenotype, epithelial phenotype, RUNX1, CBFβ, mitotic gene bookmarking

Efficacy of azacitidine is independent of molecular and clinical characteristics - an analysis of 128 patients with myelodysplastic syndromes or acute myeloid leukemia and a review of the literature Clinical Review

Andrea Kuendgen, Catharina MÃ¼ller-Thomas, Michael Lauseker, Torsten Haferlach, Petra Urbaniak, Thomas Schroeder, Carolin Brings, Michael Wulfert, Manja Meggendorfer, Barbara Hildebrandt, Beate Betz, Brigitte Royer-Pokora, Norbert Gattermann, Rainer Haas, Ulrich Germing, Katharina S. GÃ¶tze

Published Jun 12, 2018 · Vol. 9, No. 45 · pp. 27882-27894

Selective dissociation between LSD1 and GFI1B by a LSD1 inhibitor NCD38 induces the activation of ERG super-enhancer in erythroleukemia cells Research Paper

Ryusuke Yamamoto, Masahiro Kawahara, Shinji Ito, Junko Satoh, Goichi Tatsumi, Masakatsu Hishizawa, Takayoshi Suzuki, Akira Andoh

Published Apr 20, 2018 · Vol. 9, No. 30 · pp. 21007-21021

Selective inhibition of BCL-2 is a promising target in patients with high-risk myelodysplastic syndromes and adverse mutational profile Research Paper

Veronika Reidel, Johanna Kauschinger, Richard T. Hauch, Catharina MÃ¼ller-Thomas, Niroshan Nadarajah, Rainer Burgkart, Burkhard Schmidt, Dirk Hempel, Anne Jacob, Julia Slotta-Huspenina, Ulrike HÃ¶ckendorf, Christian Peschel, Wolfgang Kern, Torsten Haferlach, Katharina S. GÃ¶tze, Stefanie Jilg, Philipp J. Jost

Published Apr 3, 2018 · Vol. 9, No. 25 · pp. 17270-17281

RUNX1 and RUNX3 protect against YAP-mediated EMT, stem-ness and shorter survival outcomes in breast cancer Research Paper

Madhura Kulkarni, Tuan Zea Tan, Nurfarhanah Bte Syed Sulaiman, John M. Lamar, Prashali Bansal, Jianzhou Cui, Yiting Qiao, Yoshiaki Ito

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14175-14192

Domain retention in transcription factor fusion genes and its biological and clinical implications: a pan-cancer study Research Paper

Pora Kim, Leomar Y. Ballester, Zhongming Zhao

Published Nov 24, 2017 · Vol. 8, No. 66 · pp. 110103-110117

Dietary feeding of freeze-dried whole cranberry inhibits intestinal tumor development in Apc^min/+ mice Research Paper

Duochen Jin, Tianyu Liu, Wenxiao Dong, Yujie Zhang, Sinan Wang, Runxiang Xie, Bangmao Wang, Hailong Cao

Published Oct 26, 2017 · Vol. 8, No. 58 · pp. 97787-97800

Modeling the process of childhood ETV6-RUNX1 B-cell leukemias Review

Guillermo RodrÃguez-HernÃ¡ndez, Daniel SchÃ¤fer, Ana GavilÃ¡n, Carolina Vicente-DueÃ±as, Julia Hauer, Arndt Borkhardt, Isidro SÃ¡nchez-GarcÃa

Published Sep 27, 2017 · Vol. 8, No. 60 · pp. 102674-102680

MiR-221-regulated KIT level by wild type or leukemia mutant RUNX1: a determinant of single myeloblast fate decisions that â€“ collectively â€“ drives or hinders granulopoiesis Research Paper

Stefano Rossetti, Michael J. Anauo, Nicoletta Sacchi

Published Sep 23, 2017 · Vol. 8, No. 49 · pp. 85783-85793

RUNX1 promote invasiveness in pancreatic ductal adenocarcinoma through regulating miR-93 Research Paper

Yin Cheng, Haiyan Yang, Yang Sun, Hongkai Zhang, Shuangni Yu, Zhaohui Lu, Jie Chen

Published Aug 24, 2017 · Vol. 8, No. 59 · pp. 99567-99579

Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity Research Paper

Myoung Sook Kim, Ramkishore Gernapudi, Eun Yong Choi, Rena G. Lapidus, Antonino Passaniti

Published Aug 10, 2017 · Vol. 8, No. 41 · pp. 70916-70940

The transcriptional coregulator NAB2 is a target gene for the Wilms' tumor gene 1 protein (WT1) in leukemic cells Research Paper

Helena Jernmark Nilsson, Giorgia Montano, Tove Ullmark, Andreas Lennartsson, Kristina Drott, Linnea JÃ¤rvstrÃ¥t, BjÃ¶rn Nilsson, Karina Vidovic, Urban Gullberg

Published Aug 3, 2017 · Vol. 8, No. 50 · pp. 87136-87150

GATA2 regulates the erythropoietin receptor in t(12;21) ALL Research Paper

Marie E. Gaine, Daniel J. Sharpe, James S. Smith, Hilary A.A. Colyer, Vivien M. Hodges, Terry R. Lappin, Ken I. Mills

Published Aug 2, 2017 · Vol. 8, No. 39 · pp. 66061-66074

High expression of dedicator of cytokinesis 1 (DOCK1) confers poor prognosis in acute myeloid leukemia Research Paper

Sze-Hwei Lee, Yu-Chiao Chiu, Yi-Hung Li, Chien-Chin Lin, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien

Published Jul 31, 2017 · Vol. 8, No. 42 · pp. 72250-72259

A validated, transitional and translational porcine model of hepatocellular carcinoma Research Paper

Kyle M. Schachtschneider, Regina M. Schwind, Kwame A. Darfour-Oduro, Arun K. De, Lauretta A. Rund, Kuldeep Singh, Daniel R. Principe, Grace Guzman, Charles E. Ray Jr, Howard Ozer, Ron C. Gaba, Lawrence B. Schook

Published Jun 29, 2017 · Vol. 8, No. 38 · pp. 63620-63634

Synergistic suppression of t(8;21)-positive leukemia cell growth by combining oridonin and MAPK1/ERK2 inhibitors Research Paper

Pavel Spirin, Timofey Lebedev, Natalia Orlova, Alexey Morozov, Nadezhda Poymenova, Sergey E Dmitriev, Anton Buzdin, Carol Stocking, Olga Kovalchuk, Vladimir Prassolov

Published Jun 16, 2017 · Vol. 8, No. 34 · pp. 56991-57002

An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells Priority Research Paper

Sayyed K. Zaidi, Andrew W. Perez, Elizabeth S. White, Jane B. Lian, Janet L. Stein, Gary S. Stein

Published May 24, 2017 · Vol. 8, No. 25 · pp. 39994-40005

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Gene regulatory network and signalling pathway rewiring: How blood cancer cells shift their shapes to evade drug treatment Editorial

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Cytogenetic and molecular landscape and its potential clinical significance in Hispanic CMML patients from Puerto Rico Research Paper

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

Efficacy of azacitidine is independent of molecular and clinical characteristics - an analysis of 128 patients with myelodysplastic syndromes or acute myeloid leukemia and a review of the literature Clinical Review

Selective dissociation between LSD1 and GFI1B by a LSD1 inhibitor NCD38 induces the activation of ERG super-enhancer in erythroleukemia cells Research Paper

Selective inhibition of BCL-2 is a promising target in patients with high-risk myelodysplastic syndromes and adverse mutational profile Research Paper

RUNX1 and RUNX3 protect against YAP-mediated EMT, stem-ness and shorter survival outcomes in breast cancer Research Paper

Domain retention in transcription factor fusion genes and its biological and clinical implications: a pan-cancer study Research Paper

Dietary feeding of freeze-dried whole cranberry inhibits intestinal tumor development in Apc^min/+ mice Research Paper

Modeling the process of childhood ETV6-RUNX1 B-cell leukemias Review

MiR-221-regulated KIT level by wild type or leukemia mutant RUNX1: a determinant of single myeloblast fate decisions that â€“ collectively â€“ drives or hinders granulopoiesis Research Paper

RUNX1 promote invasiveness in pancreatic ductal adenocarcinoma through regulating miR-93 Research Paper

Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity Research Paper

The transcriptional coregulator NAB2 is a target gene for the Wilms' tumor gene 1 protein (WT1) in leukemic cells Research Paper

GATA2 regulates the erythropoietin receptor in t(12;21) ALL Research Paper

High expression of dedicator of cytokinesis 1 (DOCK1) confers poor prognosis in acute myeloid leukemia Research Paper

A validated, transitional and translational porcine model of hepatocellular carcinoma Research Paper

Synergistic suppression of t(8;21)-positive leukemia cell growth by combining oridonin and MAPK1/ERK2 inhibitors Research Paper

An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells Priority Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Gene regulatory network and signalling pathway rewiring: How blood cancer cells shift their shapes to evade drug treatment Editorial

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Cytogenetic and molecular landscape and its potential clinical significance in Hispanic CMML patients from Puerto Rico Research Paper

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

Efficacy of azacitidine is independent of molecular and clinical characteristics - an analysis of 128 patients with myelodysplastic syndromes or acute myeloid leukemia and a review of the literature Clinical Review

Selective dissociation between LSD1 and GFI1B by a LSD1 inhibitor NCD38 induces the activation of ERG super-enhancer in erythroleukemia cells Research Paper

Selective inhibition of BCL-2 is a promising target in patients with high-risk myelodysplastic syndromes and adverse mutational profile Research Paper

RUNX1 and RUNX3 protect against YAP-mediated EMT, stem-ness and shorter survival outcomes in breast cancer Research Paper

Domain retention in transcription factor fusion genes and its biological and clinical implications: a pan-cancer study Research Paper

Dietary feeding of freeze-dried whole cranberry inhibits intestinal tumor development in Apcmin/+ mice Research Paper

Modeling the process of childhood ETV6-RUNX1 B-cell leukemias Review

MiR-221-regulated KIT level by wild type or leukemia mutant RUNX1: a determinant of single myeloblast fate decisions that â€“ collectively â€“ drives or hinders granulopoiesis Research Paper

RUNX1 promote invasiveness in pancreatic ductal adenocarcinoma through regulating miR-93 Research Paper

Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity Research Paper

The transcriptional coregulator NAB2 is a target gene for the Wilms' tumor gene 1 protein (WT1) in leukemic cells Research Paper

GATA2 regulates the erythropoietin receptor in t(12;21) ALL Research Paper

High expression of dedicator of cytokinesis 1 (DOCK1) confers poor prognosis in acute myeloid leukemia Research Paper

A validated, transitional and translational porcine model of hepatocellular carcinoma Research Paper

Synergistic suppression of t(8;21)-positive leukemia cell growth by combining oridonin and MAPK1/ERK2 inhibitors Research Paper

An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells Priority Research Paper

Dietary feeding of freeze-dried whole cranberry inhibits intestinal tumor development in Apc^min/+ mice Research Paper