The Oncosearch | Oncotarget

Down-regulation of tensin2 enhances tumorigenicity and is associated with a variety of cancers Research Paper

Shiao-Ya Hong, Yi-Ping Shih, Peng Sun, Wang-Ju Hsieh, Wen-Chang Lin, Su Hao Lo

Published May 17, 2016 · Vol. 7, No. 25 · pp. 38143-38153

JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients Research Paper

Jing Qian, Weiyou Zhu, Keming Wang, Lin Ma, Jin Xu, Tongpeng Xu, Oluf Dimitri RÃ¸e, Aiping Li, Jianwei Zhou, Yongqian Shu

Published May 6, 2016 · Vol. 7, No. 24 · pp. 36865-36884

Efficacy of the combination of MEK and CDK4/6 inhibitors in vitro and in vivo in KRAS mutant colorectal cancer models Research Paper

Michael S. Lee, Timothy L. Helms, Ningping Feng, Jason Gay, Qing Edward Chang, Feng Tian, Ji Y. Wu, Carlo Toniatti, Timothy P. Heffernan, Garth Powis, Lawrence N. Kwong, Scott Kopetz

Published May 4, 2016 · Vol. 7, No. 26 · pp. 39595-39608

Des-gamma-carboxy prothrombin antagonizes the effects of Sorafenib on human hepatocellular carcinoma through activation of the Raf/MEK/ERK and PI3K/Akt/mTOR signaling pathways Research Paper

Shu-Xiang Cui, Wen-Na Shi, Zhi-Yu Song, Shu-Qing Wang, Xin-Feng Yu, Zu-Hua Gao, Xian-Jun Qu

Published May 4, 2016 · Vol. 7, No. 24 · pp. 36767-36782

Upregulation of lactate dehydrogenase a by 14-3-3ζ leads to increased glycolysis critical for breast cancer initiation and progression Research Paper

Chia-Chi Chang, Chenyu Zhang, Qingling Zhang, Ozgur Sahin, Hai Wang, Jia Xu, Yi Xiao, Jian Zhang, Sumaiyah K. Rehman, Ping Li, Mien-Chie Hung, Fariba Behbod, Dihua Yu

Published May 2, 2016 · Vol. 7, No. 23 · pp. 35270-35283

Which melanoma patient carries a BRAF-mutation? A comparison of predictive models Research Paper

Thomas Eigentler, Zeinab Assi, Jessica C. Hassel, Lucie Heinzerling, Hans Starz, Mark Berneburg, JÃ¼rgen Bauer, Claus Garbe

Published May 2, 2016 · Vol. 7, No. 24 · pp. 36130-36137

SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells Research Paper

Erin L. Wuebben, Phillip J. Wilder, Jesse L. Cox, James A. Grunkemeyer, Thomas Caffrey, Michael A. Hollingsworth, Angie Rizzino

Published Apr 26, 2016 · Vol. 7, No. 23 · pp. 34890-34906

Betacellulin induces Slug-mediated down-regulation of E-cadherin and cell migration in ovarian cancer cells Research Paper

Jianfang Zhao, Christian Klausen, Xin Qiu, Jung-Chien Cheng, Hsun-Ming Chang, Peter C.K. Leung

Published Apr 23, 2016 · Vol. 7, No. 20 · pp. 28881-28890

Synergistic antitumor effects of combination PI3K/mTOR and MEK inhibition (SAR245409 and pimasertib) in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging Research Paper

Kanako Inaba, Katsutoshi Oda, Kazuhiro Aoki, Kenbun Sone, Yuji Ikeda, Aki Miyasaka, Tomoko Kashiyama, Tomohiko Fukuda, Chinami Makii, Takahide Arimoto, Osamu Wada-Hiraike, Kei Kawana, Tetsu Yano, Yutaka Osuga, Tomoyuki Fujii

Published Apr 18, 2016 · Vol. 7, No. 20 · pp. 29577-29591

Acquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer Research Paper

Bhaskar Bhattacharya, Sarah Hong Hui Low, Mei Ling Chong, Dilys Chia, King Xin Koh, Nur Sabrina Sapari, Stanley Kaye, Huynh Hung, Touati Benoukraf, Richie Soong

Published Apr 11, 2016 · Vol. 7, No. 20 · pp. 29187-29198

Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles Research Paper

Anja E. Eisenhardt, Adrian Sprenger, Michael RÃ¶ring, Ricarda Herr, Florian Weinberg, Martin KÃ¶hler, Sandra Braun, Joachim Orth, Britta Diedrich, Ulrike Lanner, Natalja Tscherwinski, Simon Tscherwinski, Simon Schuster, Nicolas Dumaz, Enrico Schmidt, Ralf Baumeister, Andreas Schlosser, JÃ¶rn Dengjel, Tilman Brummer

Published Mar 28, 2016 · Vol. 7, No. 18 · pp. 26628-26652

Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer Research Paper

Xi-Zhou An, Zhi-Guo Zhao, Yu-Xuan Luo, Ran Zhang, Xiao-Qiang Tang, De-Long Hao, Xiang Zhao, Xiang Lv, De-Pei Liu

Published Mar 25, 2016 · Vol. 7, No. 17 · pp. 24719-24733

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer Research Paper

Jean-Philippe Foy, Antonin Tortereau, Carlos Caulin, Vincent Le Texier, Emilie Lavergne, Emilie Thomas, Sylvie Chabaud, David Perol, JoÃ«l Lachuer, Wenhua Lang, Waun Ki Hong, Patrick Goudot, Scott M. Lippman, ChloÃ© Bertolus, Pierre Saintigny

Published Mar 24, 2016 · Vol. 7, No. 24 · pp. 35932-35945

ERK2 phosphorylation of EBNA1 serine 383 residue is important for EBNA1-dependent transactivation Research Paper

Ka-Won Noh, Jihyun Park, Eun Hye Joo, Eun Kyung Lee, Eun Young Choi, Myung-Soo Kang

Published Mar 18, 2016 · Vol. 7, No. 18 · pp. 25507-25515

Hypoxia-regulated gene expression explains differences between melanoma cell line-derived xenografts and patient-derived xenografts Research Paper

Joydeep Bhadury, Berglind O. Einarsdottir, Agnieszka Podraza, Roger Olofsson Bagge, Ulrika Stierner, Lars Ny, Marcela DÃ¡vila LÃ³pez, Jonas A. Nilsson

Published Mar 18, 2016 · Vol. 7, No. 17 · pp. 23801-23811

BAY 11-7085 induces glucocorticoid receptor activation and autophagy that collaborate with apoptosis to induce human synovial fibroblast cell death Research Paper

Biserka Relic, Edith Charlier, Celine Deroyer, Olivier Malaise, Sophie Neuville, Aline Desoroux, Philippe Gillet, Dominique de Seny, Michel G. Malaise

Published Mar 14, 2016 · Vol. 7, No. 17 · pp. 23370-23382

The mTOR inhibitor Everolimus synergizes with the PI3K inhibitor GDC0941 to enhance anti-tumor efficacy in uveal melanoma Research Paper

Nabil Amirouchene-Angelozzi, Estelle Frisch-Dit-Leitz, Guillaume Carita, Ahmed Dahmani, ChloÃ© Raymondie, GÃ©raldine Liot, David Gentien, Fariba NÃ©mati, Didier Decaudin, Sergio Roman-Roman, Marie Schoumacher

Published Mar 14, 2016 · Vol. 7, No. 17 · pp. 23633-23646

ZLM-7 exhibits anti-angiogenic effects via impaired endothelial cell function and blockade of VEGF/VEGFR-2 signaling Research Paper

Min Su, Jingjia Huang, Jijia Li, Xiyuan Qin, Xiaoning Tang, Fang Jin, Shali Chen, Chuanming Jiang, Zizheng Zou, Kunjian Peng, Mohammed Nuruzzaman, Jianting Zhang, Junli Luo, Suyou Liu, Zhiyong Luo

Published Mar 8, 2016 · Vol. 7, No. 14 · pp. 19018-19030

Suppression of B-Raf(V600E) cancers by MAPK hyper-activation Research Paper

Rawan Atiq, Rachel Hertz, Sophia Eldad, Elia Smeir, Jacob Bar-Tana

Published Mar 4, 2016 · Vol. 7, No. 14 · pp. 18694-18704

Combining BRAF inhibitor and anti PD-L1 antibody dramatically improves tumor regression and anti tumor immunity in an immunocompetent murine model of anaplastic thyroid cancer Research Paper

Eran Brauner, Viswanath Gunda, Pierre Vanden Borre, David Zurakowski, Yon Seon Kim, Kate Virginia Dennett, Salma Amin, Gordon James Freeman, Sareh Parangi

Published Mar 2, 2016 · Vol. 7, No. 13 · pp. 17194-17211

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Down-regulation of tensin2 enhances tumorigenicity and is associated with a variety of cancers Research Paper

JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients Research Paper

Efficacy of the combination of MEK and CDK4/6 inhibitors in vitro and in vivo in KRAS mutant colorectal cancer models Research Paper

Des-gamma-carboxy prothrombin antagonizes the effects of Sorafenib on human hepatocellular carcinoma through activation of the Raf/MEK/ERK and PI3K/Akt/mTOR signaling pathways Research Paper

Upregulation of lactate dehydrogenase a by 14-3-3ζ leads to increased glycolysis critical for breast cancer initiation and progression Research Paper

Which melanoma patient carries a BRAF-mutation? A comparison of predictive models Research Paper

SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells Research Paper

Betacellulin induces Slug-mediated down-regulation of E-cadherin and cell migration in ovarian cancer cells Research Paper

Synergistic antitumor effects of combination PI3K/mTOR and MEK inhibition (SAR245409 and pimasertib) in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging Research Paper

Acquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer Research Paper

Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles Research Paper

Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer Research Paper

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer Research Paper

ERK2 phosphorylation of EBNA1 serine 383 residue is important for EBNA1-dependent transactivation Research Paper

Hypoxia-regulated gene expression explains differences between melanoma cell line-derived xenografts and patient-derived xenografts Research Paper

BAY 11-7085 induces glucocorticoid receptor activation and autophagy that collaborate with apoptosis to induce human synovial fibroblast cell death Research Paper

The mTOR inhibitor Everolimus synergizes with the PI3K inhibitor GDC0941 to enhance anti-tumor efficacy in uveal melanoma Research Paper

ZLM-7 exhibits anti-angiogenic effects via impaired endothelial cell function and blockade of VEGF/VEGFR-2 signaling Research Paper

Suppression of B-Raf(V600E) cancers by MAPK hyper-activation Research Paper

Combining BRAF inhibitor and anti PD-L1 antibody dramatically improves tumor regression and anti tumor immunity in an immunocompetent murine model of anaplastic thyroid cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Down-regulation of tensin2 enhances tumorigenicity and is associated with a variety of cancers Research Paper

JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients Research Paper

Efficacy of the combination of MEK and CDK4/6 inhibitors in vitro and in vivo in KRAS mutant colorectal cancer models Research Paper

Des-gamma-carboxy prothrombin antagonizes the effects of Sorafenib on human hepatocellular carcinoma through activation of the Raf/MEK/ERK and PI3K/Akt/mTOR signaling pathways Research Paper

Upregulation of lactate dehydrogenase a by 14-3-3ζ leads to increased glycolysis critical for breast cancer initiation and progression Research Paper

Which melanoma patient carries a BRAF-mutation? A comparison of predictive models Research Paper

SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells Research Paper

Betacellulin induces Slug-mediated down-regulation of E-cadherin and cell migration in ovarian cancer cells Research Paper

Synergistic antitumor effects of combination PI3K/mTOR and MEK inhibition (SAR245409 and pimasertib) in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging Research Paper

Acquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer Research Paper

Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles Research Paper

Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer Research Paper

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer Research Paper

ERK2 phosphorylation of EBNA1 serine 383 residue is important for EBNA1-dependent transactivation Research Paper

Hypoxia-regulated gene expression explains differences between melanoma cell line-derived xenografts and patient-derived xenografts Research Paper

BAY 11-7085 induces glucocorticoid receptor activation and autophagy that collaborate with apoptosis to induce human synovial fibroblast cell death Research Paper

The mTOR inhibitor Everolimus synergizes with the PI3K inhibitor GDC0941 to enhance anti-tumor efficacy in uveal melanoma Research Paper

ZLM-7 exhibits anti-angiogenic effects via impaired endothelial cell function and blockade of VEGF/VEGFR-2 signaling Research Paper

Suppression of B-Raf(V600E) cancers by MAPK hyper-activation Research Paper

Combining BRAF inhibitor and anti PD-L1 antibody dramatically improves tumor regression and anti tumor immunity in an immunocompetent murine model of anaplastic thyroid cancer Research Paper