The Oncosearch | Oncotarget

Correction: YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model Correction

Tsion Zewdu Minas, Jenny Han, Tahereh Javaheri, Sung-Hyeok Hong, Michaela Schlederer, Yasemin Saygideğer-Kont, Haydar Çelik, Kristina M. Mueller, Idil Temel, Metin Özdemirli, Heinrich Kovar, Hayriye Verda Erkizan, Jeffrey Toretsky, Lukas Kenner, Richard Moriggl, Aykut Üren

Published Sep 29, 2023 · Vol. 15, No. 1 · pp. 143-143

KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing sarcoma Research Paper

Tyler S. McCann, Janet K. Parrish, Joseph Hsieh, Marybeth Sechler, Lays M. Sobral, Chelsea Self, Kenneth L. Jones, Andrew Goodspeed, James C. Costello, Paul Jedlicka

Published Aug 29, 2020 · Vol. 11, No. 43 · pp. 3818-3831

Keywords: Ewing sarcoma, metastasis, epigenetics, Jumonji-domain histone demethylase

Ewing sarcoma family of tumors-derived small extracellular vesicle proteomics identify potential clinical biomarkers Research Paper

Glenson Samuel, Jennifer Crow, Jon B. Klein, Michael L. Merchant, Emily Nissen, Devin C. Koestler, Kris Laurence, Xiaobo Liang, Kathleen Neville, Vincent Staggs, Atif Ahmed, Safinur Atay, Andrew K. Godwin

Published Jul 7, 2020 · Vol. 11, No. 31 · pp. 2995-3012

Keywords: Ewing sarcoma, EWS-ETS, biomarkers, extracellular vesicles, exosomes

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Yetirajam Rajesh, Angana Biswas, Payel Banik, Ipsita Pal, Subhayan Das, Sachin A. Borkar, Hardik Sardana, Abhijit Saha, Swadesh K. Das, Luni Emdad, Paul B. Fisher, Mahitosh Mandal

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1097-1108

Keywords: HSPB1, RNAseq, Fli-1, radioresistant GBM, temozolomide resistant GBM

Calcitriol and non-calcemic vitamin D analogue, 22-oxacalcitriol, attenuate developmental and pathological choroidal vasculature angiogenesis ex vivo and in vivo Research Paper

Stephanie L. Merrigan, Bomina Park, Zaheer Ali, Lasse D. Jensen, Timothy W. Corson, Breandán N. Kennedy

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 493-509

Keywords: developmental angiogenesis, pathological angiogenesis, ocular angiogenesis, calcitriol, 22-oxacalcitriol

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Research Paper

Priyal O. Patel, Kathleen I. Pishas, Cenny Taslim, Julia Selich-Anderson, Emily R. Theisen, Stephen L. Lessnick

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3865-3878

Keywords: LSD2/KDM1B, Ewing sarcoma, SP-2509, LSD1/KDM1A

Downregulation of Friend Leukemia Integration 1 (FLI1) follows the stepwise progression to gastric adenocarcinoma Research Paper

Armando Del Portillo, Elena V. Komissarova, Aqiba Bokhari, Caitlin Hills, Anne Koehne de Gonzalez, Sarawut Kongkarnka, Helen E. Remotti, Jorge L. Sepulveda, Antonia R. Sepulveda

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3852-3864

Keywords: gastric cancer, FLI1, dysplasia, tumor suppressor, methylation

EWS-FLI1 low Ewing sarcoma cells demonstrate decreased susceptibility to T-cell-mediated tumor cell apoptosis Research Paper

Kelly M. Bailey, Claire M. Julian, Ariel N. Klinghoffer, Heather Bernard, Peter C. Lucas, Linda M. McAllister-Lucas

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3385-3399

Keywords: EWS-FLI1, Ewing sarcoma, T-cell, interferon, apoptosis

NKL homeobox gene NKX2-2 is aberrantly expressed in Hodgkin lymphoma Research Paper

Stefan Nagel, Roderick A.F. MacLeod, Claudia Pommerenke, Corinna Meyer, Maren Kaufmann, Hans G. Drexler

Published Dec 25, 2018 · Vol. 9, No. 101 · pp. 37480-37496

Antitumor profile of the PI3K inhibitor ZSTK474 in human sarcoma cell lines Research Paper

Nachi Namatame, Naomi Tamaki, Yuya Yoshizawa, Mutsumi Okamura, Yumiko Nishimura, Kanami Yamazaki, Miwa Tanaka, Takuro Nakamura, Kentaro Semba, Takao Yamori, Shin-ichi Yaguchi, Shingo Dan

Published Oct 12, 2018 · Vol. 9, No. 80 · pp. 35141-35161

The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth Research Paper

Janet K. Parrish, Tyler S. McCann, Marybeth Sechler, Lays M. Sobral, Wen Hua Ren, Kenneth L. Jones, Aik Choon Tan, Paul Jedlicka

Published Sep 4, 2018 · Vol. 9, No. 69 · pp. 33110-33123

The combination of epigenetic drugs SAHA and HCI-2509 synergistically inhibits EWS-FLI1 and tumor growth in Ewing sarcoma Research Paper

Daniel Jose GarcÃa-DomÃnguez, Lourdes Hontecillas-Prieto, Pablo RodrÃguez-NÃºÃ±ez, Guillem Pascual-Pasto, Monica Vila-Ubach, Rosa GarcÃa-MejÃas, MarÃa JosÃ© Robles, Oscar M. Tirado, Jaume Mora, Angel M. Carcaboso, Enrique de Ãlava

Published Jul 31, 2018 · Vol. 9, No. 59 · pp. 31397-31410

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers Research Paper

Kalliopi Tsafou, Anna Maria Katschnig, Branka Radic-Sarikas, Cornelia NoÃ«lle Mutz, Kristiina Iljin, Raphaela Schwentner, Maximilian O. Kauer, Karin MÃ¼hlbacher, Dave N.T. Aryee, David Westergaard, Saija Haapa-Paananen, Vidal Fey, Giulio Superti-Furga, Jeffrey Toretsky, SÃ¸ren Brunak, Heinrich Kovar

Published Jul 24, 2018 · Vol. 9, No. 57 · pp. 31018-31031

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma Research Paper

Yu Tanabe, Yoshiyuki Suehara, Shinji Kohsaka, Takuo Hayashi, Keisuke Akaike, Kenta Mukaihara, Taisei Kurihara, Youngji Kim, Taketo Okubo, Midori Ishii, Saiko Kazuno, Kazuo Kaneko, Tsuyoshi Saito

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14428-14443

EWS-FLI1 and RNA helicase A interaction inhibitor YK-4-279 inhibits growth of neuroblastoma Research Paper

Wenjing Sun, Yesenia Rojas, Hao Wang, Yang Yu, Yongfeng Wang, Zhenghu Chen, Kimal Rajapakshe, Xin Xu, Wei Huang, Saurabh Agarwal, Roma H. Patel, Sarah Woodfield, Yanling Zhao, Jingling Jin, Hong Zhang, Angela Major, M. John Hicks, Jason M. Shohet, Sanjeev A. Vasudevan, Cristian Coarfa, Jianhua Yang, Jed G. Nuchtern

Published Oct 19, 2017 · Vol. 8, No. 55 · pp. 94780-94792

Sensitizing Ewing sarcoma to chemo- and radiotherapy by inhibition of the DNA-repair enzymes DNA protein kinase (DNA-PK) and poly-ADP-ribose polymerase (PARP) 1/2 Research Paper

Britta Vormoor, Yvonne T. Schlosser, Helen Blair, Abhishek Sharma, Sarah Wilkinson, David R. Newell, Nicola Curtin

Published Sep 28, 2017 · Vol. 8, No. 69 · pp. 113418-113430

Size-based detection of sarcoma circulating tumor cells and cell clusters Research Paper

Masanori Hayashi, Peixuan Zhu, Gregory McCarty, Christian F. Meyer, Christine A. Pratilas, Adam Levin, Carol D. Morris, Catherine M. Albert, Kyle W. Jackson, Cha-Mei Tang, David M. Loeb

Published Aug 24, 2017 · Vol. 8, No. 45 · pp. 78965-78977

Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets Research Paper

Michaela C. Baldauf, Martin F. Orth, Marlene Dallmayer, Aruna Marchetto, Julia S. Gerke, Rebeca Alba Rubio, Merve M. Kiran, Julian Musa, Maximilian M. L. Knott, Shunya Ohmura, Jing Li, Nusret Akpolat, Ayse N. Akatli, Ã–zlem Ã–zen, Uta Dirksen, Wolfgang Hartmann, Enrique de Alava, Daniel Baumhoer, Giuseppina Sannino, Thomas Kirchner, Thomas G. P. GrÃ¼newald

Published Aug 4, 2017 · Vol. 9, No. 2 · pp. 1587-1601

Inhibition of CHK1 sensitizes Ewing sarcoma cells to the ribonucleotide reductase inhibitor gemcitabine Research Paper

Kelli L. Goss, Stacia L. Koppenhafer, Kathryn M. Harmoney, William W. Terry, David J. Gordon

Published Jun 28, 2017 · Vol. 8, No. 50 · pp. 87016-87032

Friend leukemia virus integration 1 promotes tumorigenesis of small cell lung cancer cells by activating the miR-17-92 pathway Research Paper

Lingyu Li, Wei Song, Xu Yan, Ailing Li, Xiaoying Zhang, Wei Li, Xue Wen, Lei Zhou, Dehai Yu, Ji-Fan Hu, Jiuwei Cui

Published Mar 30, 2017 · Vol. 8, No. 26 · pp. 41975-41987

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Correction: YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model Correction

KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing sarcoma Research Paper

Ewing sarcoma family of tumors-derived small extracellular vesicle proteomics identify potential clinical biomarkers Research Paper

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Calcitriol and non-calcemic vitamin D analogue, 22-oxacalcitriol, attenuate developmental and pathological choroidal vasculature angiogenesis ex vivo and in vivo Research Paper

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Research Paper

Downregulation of Friend Leukemia Integration 1 (FLI1) follows the stepwise progression to gastric adenocarcinoma Research Paper

EWS-FLI1 low Ewing sarcoma cells demonstrate decreased susceptibility to T-cell-mediated tumor cell apoptosis Research Paper

NKL homeobox gene NKX2-2 is aberrantly expressed in Hodgkin lymphoma Research Paper

Antitumor profile of the PI3K inhibitor ZSTK474 in human sarcoma cell lines Research Paper

The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth Research Paper

The combination of epigenetic drugs SAHA and HCI-2509 synergistically inhibits EWS-FLI1 and tumor growth in Ewing sarcoma Research Paper

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers Research Paper

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma Research Paper

EWS-FLI1 and RNA helicase A interaction inhibitor YK-4-279 inhibits growth of neuroblastoma Research Paper

Sensitizing Ewing sarcoma to chemo- and radiotherapy by inhibition of the DNA-repair enzymes DNA protein kinase (DNA-PK) and poly-ADP-ribose polymerase (PARP) 1/2 Research Paper

Size-based detection of sarcoma circulating tumor cells and cell clusters Research Paper

Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets Research Paper

Inhibition of CHK1 sensitizes Ewing sarcoma cells to the ribonucleotide reductase inhibitor gemcitabine Research Paper

Friend leukemia virus integration 1 promotes tumorigenesis of small cell lung cancer cells by activating the miR-17-92 pathway Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Correction: YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model Correction

KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing sarcoma Research Paper

Ewing sarcoma family of tumors-derived small extracellular vesicle proteomics identify potential clinical biomarkers Research Paper

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Calcitriol and non-calcemic vitamin D analogue, 22-oxacalcitriol, attenuate developmental and pathological choroidal vasculature angiogenesis ex vivo and in vivo Research Paper

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Research Paper

Downregulation of Friend Leukemia Integration 1 (FLI1) follows the stepwise progression to gastric adenocarcinoma Research Paper

EWS-FLI1 low Ewing sarcoma cells demonstrate decreased susceptibility to T-cell-mediated tumor cell apoptosis Research Paper

NKL homeobox gene NKX2-2 is aberrantly expressed in Hodgkin lymphoma Research Paper

Antitumor profile of the PI3K inhibitor ZSTK474 in human sarcoma cell lines Research Paper

The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth Research Paper

The combination of epigenetic drugs SAHA and HCI-2509 synergistically inhibits EWS-FLI1 and tumor growth in Ewing sarcoma Research Paper

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers Research Paper

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma Research Paper

EWS-FLI1 and RNA helicase A interaction inhibitor YK-4-279 inhibits growth of neuroblastoma Research Paper

Sensitizing Ewing sarcoma to chemo- and radiotherapy by inhibition of the DNA-repair enzymes DNA protein kinase (DNA-PK) and poly-ADP-ribose polymerase (PARP) 1/2 Research Paper

Size-based detection of sarcoma circulating tumor cells and cell clusters Research Paper

Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets Research Paper

Inhibition of CHK1 sensitizes Ewing sarcoma cells to the ribonucleotide reductase inhibitor gemcitabine Research Paper

Friend leukemia virus integration 1 promotes tumorigenesis of small cell lung cancer cells by activating the miR-17-92 pathway Research Paper