The Oncosearch | Oncotarget

The long winding road to the safer glucocorticoid receptor (GR) targeting therapies Review

Ekaterina A. Lesovaya, Daria Chudakova, Gleb Baida, Ekaterina M. Zhidkova, Kirill I. Kirsanov, Marianna G. Yakubovskaya, Irina V. Budunova

Published Feb 1, 2022 · Vol. 13, No. 1 · pp. 408-424

Keywords: glucocorticoid receptor, glucocorticoids, SEGRAM, REDD1, drug repurposing

Deletion of the glucocorticoid receptor chaperone FKBP51 prevents glucocorticoid-induced skin atrophy Research Paper

Gleb Baida, Pankaj Bhalla, Alexander Yemelyanov, Lance A. Stechschulte, Weinian Shou, Ben Readhead, Joel T. Dudley, Edwin R. SÃ¡nchez, Irina Budunova

Published Oct 5, 2018 · Vol. 9, No. 78 · pp. 34772-34783

A regulatory role for the co-chaperone FKBP51s in PD-L1 expression in glioma Research Paper

Paolo D'Arrigo, Michele Russo, Anna Rea, Martina Tufano, Elia Guadagno, Maria Laura Del Basso De Caro, Roberto Pacelli, Felix Hausch, Stefania Staibano, Gennaro Ilardi, Silvia Parisi, Maria Fiammetta Romano, Simona Romano

Published Jul 17, 2017 · Vol. 8, No. 40 · pp. 68291-68304

FKBP51 decreases cell proliferation and increases progestin sensitivity of human endometrial adenocarcinomas by inhibiting Akt Research Paper

Jing Dong, Yulian Jiao, Wenli Mu, Bingru Lu, Muyun Wei, Linying Sun, Shengnan Hu, Bin Cui, Xiaowen Liu, Zijiang Chen, Yueran Zhao

Published Jun 30, 2017 · Vol. 8, No. 46 · pp. 80405-80415

Rapalogs can promote cancer cell stemness in vitro in a Galectin-1 and H-ras-dependent manner Research Paper

Itziar M.D Posada, Benoit Lectez, Mukund Sharma, Christina Oetken-Lindholm, Laxman Yetukuri, Yong Zhou, Tero Aittokallio, Daniel Abankwa

Published May 11, 2017 · Vol. 8, No. 27 · pp. 44550-44566

Integration of zebrafish fin regeneration genes with expression data of human tumors in silico uncovers potential novel melanoma markers Research Paper

Martin Hagedorn, GÃ©raldine Siegfried, Katarzyna B. Hooks, Abdel-Majid Khatib

Published Sep 26, 2016 · Vol. 7, No. 44 · pp. 71567-71579

Everolimus induces Met inactivation by disrupting the FKBP12/Met complex Research Paper

Lucia Raimondo, Valentina Dâ€™Amato, Alberto Servetto, Roberta Rosa, Roberta Marciano, Luigi Formisano, Concetta Di Mauro, Roberta Clara Orsini, Priscilla Cascetta, Paola Ciciola, Ana Paula De Maio, Maria Flavia Di Renzo, Sandro Cosconati, Agostino Bruno, Antonio Randazzo, Filomena Napolitano, Nunzia Montuori, Bianca Maria Veneziani, Sabino De Placido, Roberto Bianco

Published May 19, 2016 · Vol. 7, No. 26 · pp. 40073-40084

The joining of the Hsp90 and Hsp70 chaperone cycles yields transient interactions and stable intermediates: insights from mass spectrometry Research Perspective

Carla Schmidt, Victoria Beilsten-Edmands, Carol V. Robinson

Published Jul 22, 2015 · Vol. 6, No. 21 · pp. 18276-18281

p53 and rapamycin are additive Priority Research Paper

Barbara Christy, Marco Demaria, Judith Campisi, Jing Huang, Diane Jones, Sherry G. Dodds, Charnae Williams, Gene Hubbard, Carolina B. Livi, Xiaoli Gao, Susan Weintraub, Tyler Curiel, Z. Dave Sharp, Paul Hasty

Published Jun 23, 2015 · Vol. 6, No. 18 · pp. 15802-15813

Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response Research Paper

Nian-Kang Sun, Shang-Lang Huang, Pu-Yuan Chang, Hsing-Pang Lu, Chuck C.-K. Chao

Published Nov 17, 2014 · Vol. 5, No. 23 · pp. 11939-11956

Catalytic mTOR inhibitors can overcome intrinsic and acquired resistance to allosteric mTOR inhibitors Research Paper

Burhan Hassan, Argun Akcakanat, Takafumi Sangai, Kurt W. Evans, Farrell Adkins, Agda Karina Eterovic, Hao Zhao, Ken Chen, Huiqin Chen, Kim-Anh Do, Shelly M. Xie, Ashley M. Holder, Aung Naing, Gordon B. Mills, Funda Meric-Bernstam

Published Aug 10, 2014 · Vol. 5, No. 18 · pp. 8544-8557

Insights from yeast into whether the rapamycin inhibition of heat shock transcription factor (Hsf1) can prevent the Hsf1 activation that results from treatment with an Hsp90 inhibitor Research Paper

Stefan H. Millson, Peter W. Piper

Published Jun 7, 2014 · Vol. 5, No. 13 · pp. 5054-5064

Chaperones and the maturation of steroid hormone receptor complexes Commentary

Yizhi Jane Tao, Wenjie Zheng

Published Mar 10, 2011 · Vol. 2, No. 3 · pp. 104-106

Hsp90 can Accommodate the Simultaneous Binding of the FKBP52 and HOP Proteins Research Paper

Zacariah L. Hildenbrand, Sudheer K. Molugu, Nadia Herrera, Citlally Ramirez, Chuan Xiao, Ricardo A. Bernal

Published Feb 28, 2011 · Vol. 2, No. 1-2 · pp. 43-58

Keywords: Hsp90, HOP, FKBP52, p23, Androgen Receptor Activation, hormone-dependent cancer, molecular chaperone

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The long winding road to the safer glucocorticoid receptor (GR) targeting therapies Review

Deletion of the glucocorticoid receptor chaperone FKBP51 prevents glucocorticoid-induced skin atrophy Research Paper

A regulatory role for the co-chaperone FKBP51s in PD-L1 expression in glioma Research Paper

FKBP51 decreases cell proliferation and increases progestin sensitivity of human endometrial adenocarcinomas by inhibiting Akt Research Paper

Rapalogs can promote cancer cell stemness in vitro in a Galectin-1 and H-ras-dependent manner Research Paper

Integration of zebrafish fin regeneration genes with expression data of human tumors in silico uncovers potential novel melanoma markers Research Paper

Everolimus induces Met inactivation by disrupting the FKBP12/Met complex Research Paper

The joining of the Hsp90 and Hsp70 chaperone cycles yields transient interactions and stable intermediates: insights from mass spectrometry Research Perspective

p53 and rapamycin are additive Priority Research Paper

Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response Research Paper

Catalytic mTOR inhibitors can overcome intrinsic and acquired resistance to allosteric mTOR inhibitors Research Paper

Insights from yeast into whether the rapamycin inhibition of heat shock transcription factor (Hsf1) can prevent the Hsf1 activation that results from treatment with an Hsp90 inhibitor Research Paper

Chaperones and the maturation of steroid hormone receptor complexes Commentary

Hsp90 can Accommodate the Simultaneous Binding of the FKBP52 and HOP Proteins Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

The long winding road to the safer glucocorticoid receptor (GR) targeting therapies Review

Deletion of the glucocorticoid receptor chaperone FKBP51 prevents glucocorticoid-induced skin atrophy Research Paper

A regulatory role for the co-chaperone FKBP51s in PD-L1 expression in glioma Research Paper

FKBP51 decreases cell proliferation and increases progestin sensitivity of human endometrial adenocarcinomas by inhibiting Akt Research Paper

Rapalogs can promote cancer cell stemness in vitro in a Galectin-1 and H-ras-dependent manner Research Paper

Integration of zebrafish fin regeneration genes with expression data of human tumors in silico uncovers potential novel melanoma markers Research Paper

Everolimus induces Met inactivation by disrupting the FKBP12/Met complex Research Paper

The joining of the Hsp90 and Hsp70 chaperone cycles yields transient interactions and stable intermediates: insights from mass spectrometry Research Perspective

p53 and rapamycin are additive Priority Research Paper

Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response Research Paper

Catalytic mTOR inhibitors can overcome intrinsic and acquired resistance to allosteric mTOR inhibitors Research Paper

Insights from yeast into whether the rapamycin inhibition of heat shock transcription factor (Hsf1) can prevent the Hsf1 activation that results from treatment with an Hsp90 inhibitor Research Paper

Chaperones and the maturation of steroid hormone receptor complexes Commentary

Hsp90 can Accommodate the Simultaneous Binding of the FKBP52 and HOP Proteins Research Paper