The Oncosearch | Oncotarget

Widespread folate receptor expression in pediatric and adolescent solid tumors - opportunity for intraoperative visualization with the novel fluorescent agent pafolacianine Research Paper

Ashley C. Dodd, Nitin R. Wadhwani, Alison Lehane, Rom Brown, Kyle L. MacQuarrie, Seth D. Goldstein, Timothy B. Lautz

Published Oct 13, 2025 · Vol. 16, No. 1 · pp. 759-767

Keywords: folate receptor, fluorescent-guided surgery, pediatric tumors, pafolacianine, RNA sequencing

Correction: Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Correction

Wen Luo, Changxin Xu, Sarah Phillips, Aliza Gardenswartz, Jeremy M. Rosenblum, Janet Ayello, Stephen L. Lessnick, Huai-Xiang Hao, Mitchell S. Cairo

Published Mar 3, 2023

Correction: Bone marrow involvement identifies a subgroup of advanced Ewing sarcoma patients with fatal outcome irrespective of therapy in contrast to curable patients with multiple bone metastases but unaffected marrow Correction

Uwe Thiel, Angela Wawer, Irene von Luettichau, Hans-Ulrich Bender, Franziska Blaeschke, Thomas G.P. Grunewald, Marc Steinborn, Barbara Röper, Halvard Bonig, Thomas Klingebiel, Peter Bader, Ewa Koscielniak, Michael Paulussen, Uta Dirksen, Heribert Juergens, Hans-Jochem Kolb, Stefan E.G. Burdach

Published Jan 25, 2022

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

Chandni Desai, Jon Thomason, Jordan L. Kohlmeyer, Anna C. Reisetter, Parmanand Ahirwar, Khadijeh Jahanseir, Mariah Leidinger, Georgina Ofori-Amanfo, Karen Fritchie, Sadanandan E. Velu, Patrick Breheny, Dawn E. Quelle, Munir R. Tanas

Published Mar 21, 2021 · Vol. 12, No. 8 · pp. 740-755

Keywords: sarcoma, YAP, TAZ, p53-MDM2, RABL6A

KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing sarcoma Research Paper

Tyler S. McCann, Janet K. Parrish, Joseph Hsieh, Marybeth Sechler, Lays M. Sobral, Chelsea Self, Kenneth L. Jones, Andrew Goodspeed, James C. Costello, Paul Jedlicka

Published Aug 29, 2020 · Vol. 11, No. 43 · pp. 3818-3831

Keywords: Ewing sarcoma, metastasis, epigenetics, Jumonji-domain histone demethylase

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

Matthew J. Kling, Nagendra K. Chaturvedi, Varun Kesherwani, Don W. Coulter, Timothy R. McGuire, J. Graham Sharp, Shantaram S. Joshi

Published Jul 30, 2020 · Vol. 11, No. 40 · pp. 3633-3645

Keywords: exosomes, hypoxia, Ewing’s sarcoma, stemness, miR-210

Ewing sarcoma family of tumors-derived small extracellular vesicle proteomics identify potential clinical biomarkers Research Paper

Glenson Samuel, Jennifer Crow, Jon B. Klein, Michael L. Merchant, Emily Nissen, Devin C. Koestler, Kris Laurence, Xiaobo Liang, Kathleen Neville, Vincent Staggs, Atif Ahmed, Safinur Atay, Andrew K. Godwin

Published Jul 7, 2020 · Vol. 11, No. 31 · pp. 2995-3012

Keywords: Ewing sarcoma, EWS-ETS, biomarkers, extracellular vesicles, exosomes

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Wen Luo, Changxin Xu, Sarah Phillips, Aliza Gardenswartz, Jeremy M. Rosenblum, Janet Ayello, Stephen L. Lessnick, Huai-Xiang Hao, Mitchell S. Cairo

Published Apr 16, 2020 · Vol. 11, No. 19 · pp. 1691-1704

Keywords: PPP1R1A, cell cycle control, IGF-1R, metastasis, Ewing sarcoma

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

John M. Idso, Shunhua Lao, Nathan J. Schloemer, Jeffrey Knipstein, Robert Burns, Monica S. Thakar, Subramaniam Malarkannan

Published Mar 25, 2020 · Vol. 11, No. 20 · pp. 1799-1815

Keywords: NK cells, histone deacetylase inhibitor, Ewing sarcoma, rhabdomyosarcoma, immunotherapy

Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy Research Paper

Caitlin D. Lowery, Wayne Blosser, Michele Dowless, Matthew Renschler, Lisa V. Perez, Jennifer Stephens, Bronislaw Pytowski, Heather Wasserstrom, Louis F. Stancato, Beverly Falcon

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5523-5533

Keywords: angiogenesis, pediatric cancer, VEGFR2, ramucirumab, DC101

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Research Paper

Priyal O. Patel, Kathleen I. Pishas, Cenny Taslim, Julia Selich-Anderson, Emily R. Theisen, Stephen L. Lessnick

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3865-3878

Keywords: LSD2/KDM1B, Ewing sarcoma, SP-2509, LSD1/KDM1A

EWS-FLI1 low Ewing sarcoma cells demonstrate decreased susceptibility to T-cell-mediated tumor cell apoptosis Research Paper

Kelly M. Bailey, Claire M. Julian, Ariel N. Klinghoffer, Heather Bernard, Peter C. Lucas, Linda M. McAllister-Lucas

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3385-3399

Keywords: EWS-FLI1, Ewing sarcoma, T-cell, interferon, apoptosis

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Review

Stefano Guadagni, Giammaria Fiorentini, Andrea Mambrini, Francesco Masedu, Marco Valenti, Andrew Reay Mackay, Donatella Sarti, Enrico Ricevuto, Marco Clementi, Marco Catarci, Gianni Lazzarin, Gemma Bruera

Published May 14, 2019

Keywords: hypoxic pelvic perfusion with mitomycin C and oxaliplatin, unresectable recurrent rectal cancer, retrospective cohort study

Prospective investigation of drug resistance: an approach to understanding and optimizing the clinical benefit of targeted agents in Ewing sarcoma News

Kelly M. Bailey

Published Dec 8, 2018 · Vol. 9, No. 99 · pp. 37270-37271

Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation Research Paper

Kathleen I. Pishas, Stephen L. Lessnick

Published Nov 23, 2018 · Vol. 9, No. 92 · pp. 36413-36429

Antitumor profile of the PI3K inhibitor ZSTK474 in human sarcoma cell lines Research Paper

Nachi Namatame, Naomi Tamaki, Yuya Yoshizawa, Mutsumi Okamura, Yumiko Nishimura, Kanami Yamazaki, Miwa Tanaka, Takuro Nakamura, Kentaro Semba, Takao Yamori, Shin-ichi Yaguchi, Shingo Dan

Published Oct 12, 2018 · Vol. 9, No. 80 · pp. 35141-35161

The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth Research Paper

Janet K. Parrish, Tyler S. McCann, Marybeth Sechler, Lays M. Sobral, Wen Hua Ren, Kenneth L. Jones, Aik Choon Tan, Paul Jedlicka

Published Sep 4, 2018 · Vol. 9, No. 69 · pp. 33110-33123

The combination of epigenetic drugs SAHA and HCI-2509 synergistically inhibits EWS-FLI1 and tumor growth in Ewing sarcoma Research Paper

Daniel Jose GarcÃa-DomÃnguez, Lourdes Hontecillas-Prieto, Pablo RodrÃguez-NÃºÃ±ez, Guillem Pascual-Pasto, Monica Vila-Ubach, Rosa GarcÃa-MejÃas, MarÃa JosÃ© Robles, Oscar M. Tirado, Jaume Mora, Angel M. Carcaboso, Enrique de Ãlava

Published Jul 31, 2018 · Vol. 9, No. 59 · pp. 31397-31410

The impact of nuts consumption on glucose/insulin homeostasis and inflammation markers mediated by adiposity factors among American adults Research Paper

Mohsen Mazidi, Hassan Vatanparast, Niki Katsiki, Maciej Banach

Published Jul 27, 2018 · Vol. 9, No. 58 · pp. 31173-31186

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers Research Paper

Kalliopi Tsafou, Anna Maria Katschnig, Branka Radic-Sarikas, Cornelia NoÃ«lle Mutz, Kristiina Iljin, Raphaela Schwentner, Maximilian O. Kauer, Karin MÃ¼hlbacher, Dave N.T. Aryee, David Westergaard, Saija Haapa-Paananen, Vidal Fey, Giulio Superti-Furga, Jeffrey Toretsky, SÃ¸ren Brunak, Heinrich Kovar

Published Jul 24, 2018 · Vol. 9, No. 57 · pp. 31018-31031

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Widespread folate receptor expression in pediatric and adolescent solid tumors - opportunity for intraoperative visualization with the novel fluorescent agent pafolacianine Research Paper

Correction: Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Correction

Correction: Bone marrow involvement identifies a subgroup of advanced Ewing sarcoma patients with fatal outcome irrespective of therapy in contrast to curable patients with multiple bone metastases but unaffected marrow Correction

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing sarcoma Research Paper

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

Ewing sarcoma family of tumors-derived small extracellular vesicle proteomics identify potential clinical biomarkers Research Paper

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy Research Paper

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Research Paper

EWS-FLI1 low Ewing sarcoma cells demonstrate decreased susceptibility to T-cell-mediated tumor cell apoptosis Research Paper

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Review

Prospective investigation of drug resistance: an approach to understanding and optimizing the clinical benefit of targeted agents in Ewing sarcoma News

Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation Research Paper

Antitumor profile of the PI3K inhibitor ZSTK474 in human sarcoma cell lines Research Paper

The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth Research Paper

The combination of epigenetic drugs SAHA and HCI-2509 synergistically inhibits EWS-FLI1 and tumor growth in Ewing sarcoma Research Paper

The impact of nuts consumption on glucose/insulin homeostasis and inflammation markers mediated by adiposity factors among American adults Research Paper

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers Research Paper

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European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Widespread folate receptor expression in pediatric and adolescent solid tumors - opportunity for intraoperative visualization with the novel fluorescent agent pafolacianine Research Paper

Correction: Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Correction

Correction: Bone marrow involvement identifies a subgroup of advanced Ewing sarcoma patients with fatal outcome irrespective of therapy in contrast to curable patients with multiple bone metastases but unaffected marrow Correction

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing sarcoma Research Paper

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

Ewing sarcoma family of tumors-derived small extracellular vesicle proteomics identify potential clinical biomarkers Research Paper

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy Research Paper

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Research Paper

EWS-FLI1 low Ewing sarcoma cells demonstrate decreased susceptibility to T-cell-mediated tumor cell apoptosis Research Paper

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Review

Prospective investigation of drug resistance: an approach to understanding and optimizing the clinical benefit of targeted agents in Ewing sarcoma News

Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation Research Paper

Antitumor profile of the PI3K inhibitor ZSTK474 in human sarcoma cell lines Research Paper

The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth Research Paper

The combination of epigenetic drugs SAHA and HCI-2509 synergistically inhibits EWS-FLI1 and tumor growth in Ewing sarcoma Research Paper

The impact of nuts consumption on glucose/insulin homeostasis and inflammation markers mediated by adiposity factors among American adults Research Paper

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers Research Paper