The Oncosearch | Oncotarget

Hypothesis: HPV E6 and COVID spike proteins cooperate in targeting tumor suppression by p53 Hypothesis

Wafik S. El-Deiry

Published Mar 30, 2026 · Vol. 17, No. 1 · pp. 30-33

Keywords: HPV, COVID, p53, spike, cancer

NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer Research Paper

Travis P. Schrank, Andrew C. Prince, Tejas Sathe, Xiaowei Wang, Xinyi Liu, Damir T. Alzhanov, Barbara Burtness, Albert S. Baldwin, Wendell G. Yarbrough, Natalia Issaeva

Published May 7, 2022 · Vol. 13, No. 1 · pp. 707-722

Keywords: HPV, head and neck cancer, CYLD, TRAF3, NF-κB

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Catherine T. Haring, Chandan Bhambhani, Collin Brummel, Brittany Jewell, Emily Bellile, Molly E. Heft Neal, Erin Sandford, Ryan M. Spengler, Apurva Bhangale, Matthew E. Spector, Jonathan McHugh, Mark E. Prince, Michelle Mierzwa, Francis P. Worden, Muneesh Tewari, Paul L. Swiecicki, J. Chad Brenner

Published Jun 11, 2021 · Vol. 12, No. 13 · pp. 1214-1229

Keywords: HPV, head and neck cancer, oropharyngeal cancer, ctDNA, circulating tumor DNA

A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV⁺ head and neck squamous cell carcinomas Research Paper

Lennox Chitsike, Chung-Hsiang Yuan, Anuradha Roy, Kristopher Boyle, Penelope J. Duerksen-Hughes

Published Feb 22, 2021 · Vol. 12, No. 6 · pp. 549-561

Keywords: HNSCC, HPV, E6, AlphaScreen™, 30-hydroxygambogic acid

Evidence for context-dependent functions of KDM5B in prostate development and prostate cancer Research Paper

Bigang Liu, Rahul Kumar, Hseuh-Ping Chao, Rashid Mehmood, Yibing Ji, Amanda Tracz, Dean G. Tang

Published Nov 10, 2020 · Vol. 11, No. 46 · pp. 4243-4252

Keywords: KDM5B, prostate cancer, prostate development, hyperplasia, epigenetics

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Mei Zhang, Angela M. Hong

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1417-1426

Keywords: radiosensitivity, oropharyngeal cancer, human papillomavirus, double-strand break, radiobiology

Lactate induces PD-L1 in HRAS^G12V-positive oropharyngeal squamous cell carcinoma Research Paper

Alexander K. Verma, Shanta M. Messerli, W. Keith Miskimins

Published Nov 15, 2019 · Vol. 11, No. 17 · pp. 1493-1504

Keywords: oropharyngeal cancer, lactate, Ras, anti-tumor immunity, PD-L1

Assessment of circularized E7 RNA, GLUT1, and PD-L1 in anal squamous cell carcinoma Research Paper

Bahir H. Chamseddin, Eunice E. Lee, Jiwoong Kim, Xiaowei Zhan, Rong Yang, Kathleen M. Murphy, Cheryl Lewis, Gregory A. Hosler, Suntrea T. Hammer, Richard C. Wang

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5958-5969

Keywords: anal squamous cell carcinoma, circular RNA, GLUT1, human papillomavirus, PD-L1

Defining molecular risk in ALK⁺ NSCLC Research Perspective

Petros Christopoulos, Jan Budczies, Martina Kirchner, Steffen Dietz, Holger SÃ¼ltmann, Michael Thomas, Albrecht Stenzinger

Published May 3, 2019 · Vol. 10, No. 33 · pp. 3093-3103

Phospholipidation of nuclear proteins by the human papillomavirus E6 oncoprotein: implication in carcinogenesis Research Paper

Benjamin Marx, Martin Hufbauer, Paola Zigrino, Slawomir Majewski, Birgid Markiefka, Timo Sachsenheimer, Britta BrÃ¼gger, Baki AkgÃ¼l

Published Sep 25, 2018 · Vol. 9, No. 75 · pp. 34142-34158

Silencing of casein kinase 1 delta reduces migration and metastasis of triple negative breast cancer cells Research Paper

Isabelle Bar, Ahmad Merhi, Lionel Larbanoix, Manuel Constant, Sandy Haussy, Sophie Laurent, Jean-Luc Canon, Paul DelrÃ©e

Published Jul 20, 2018 · Vol. 9, No. 56 · pp. 30821-30836

Viral DNA integration and methylation of human papillomavirus type 16 in high-grade oral epithelial dysplasia and head and neck squamous cell carcinoma Research Paper

Sujita Khanal, Brian S. Shumway, Maryam Zahin, Rebecca A. Redman, John D. Strickley, Patrick J. Trainor, Shesh N. Rai, Shin-je Ghim, Alfred Bennett Jenson, Joongho Joh

Published Jul 13, 2018 · Vol. 9, No. 54 · pp. 30419-30433

Sensitive molecular detection of small nodal metastasis in uterine cervical cancer using HPV16-E6/CK19/MUC1 cancer biomarkers Research Paper

Vanessa SamouÃ«lian, Nawel Mechtouf, Eric Leblanc, Guillaume B. Cardin, ValÃ©rie Lhotellier, Denis Querleu, FranÃ§oise RÃ©villion, Francis Rodier

Published Apr 24, 2018 · Vol. 9, No. 31 · pp. 21641-21654

High infiltration of CD68+ macrophages is associated with poor prognoses of head and neck squamous cell carcinoma patients and is influenced by human papillomavirus Research Paper

Imelda Seminerio, NadÃ¨ge Kindt, GÃ©raldine Descamps, Justine Bellier, JÃ©rÃ´me R. Lechien, Quentin Mat, Charles Pottier, Fabrice JournÃ©, Sven Saussez

Published Jan 24, 2018 · Vol. 9, No. 13 · pp. 11046-11059

Cis-trimethoxy resveratrol induces intrinsic apoptosis via prometaphase arrest and prolonged CDK1 activation pathway in human Jurkat T cells Research Paper

Chae Eun Kim, Do Youn Jun, Jong-Sik Kim, Young Ho Kim

Published Dec 22, 2017 · Vol. 9, No. 4 · pp. 4969-4984

Progesterone and calcitriol reduce invasive potential of endometrial cancer cells by targeting ARF6, NEDD9 and MT1-MMP Research Paper

Sana Waheed, Batsukh Dorjbal, Chad A. Hamilton, G. Larry Maxwell, Gustavo C. Rodriguez, Viqar Syed

Published Nov 28, 2017 · Vol. 8, No. 69 · pp. 113583-113597

Cell death and restoration of TRAIL-sensitivity by ciglitazone in resistant cervical cancer cells Research Paper

Marie-Laure Plissonnier, Sylvie Fauconnet, Hugues Bittard, Christiane Mougin, Jean Rommelaere, Isabelle Lascombe

Published Nov 22, 2017 · Vol. 8, No. 64 · pp. 107744-107762

Twist1 mediated regulation of glioma tumorigenicity is dependent on mode of mouse neural progenitor transformation Research Paper

Andrei M. Mikheev, Svetlana A. Mikheeva, Mari Tokita, Liza J. Severs, Robert C. Rostomily

Published Nov 21, 2017 · Vol. 8, No. 64 · pp. 107716-107729

Expression characteristics of the plasmid-borne mcr-1 colistin resistance gene Research Paper

Haifang Zhang, Minhui Miao, Jieting Yan, Min Wang, Yi-Wei Tang, Barry N. Kreiswirth, Xia Zhang, Liang Chen, Hong Du

Published Nov 20, 2017 · Vol. 8, No. 64 · pp. 107596-107602

Viral E6/E7 oncogene and cellular hexokinase 2 expression in HPV-positive cancer cell lines Research Paper

Karin Hoppe-Seyler, Anja Honegger, Felicitas Bossler, Jasmin Sponagel, Julia Bulkescher, Claudia Lohrey, Felix Hoppe-Seyler

Published Nov 15, 2017 · Vol. 8, No. 63 · pp. 106342-106351

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Hypothesis: HPV E6 and COVID spike proteins cooperate in targeting tumor suppression by p53 Hypothesis

NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer Research Paper

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV⁺ head and neck squamous cell carcinomas Research Paper

Evidence for context-dependent functions of KDM5B in prostate development and prostate cancer Research Paper

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Lactate induces PD-L1 in HRAS^G12V-positive oropharyngeal squamous cell carcinoma Research Paper

Assessment of circularized E7 RNA, GLUT1, and PD-L1 in anal squamous cell carcinoma Research Paper

Defining molecular risk in ALK⁺ NSCLC Research Perspective

Phospholipidation of nuclear proteins by the human papillomavirus E6 oncoprotein: implication in carcinogenesis Research Paper

Silencing of casein kinase 1 delta reduces migration and metastasis of triple negative breast cancer cells Research Paper

Viral DNA integration and methylation of human papillomavirus type 16 in high-grade oral epithelial dysplasia and head and neck squamous cell carcinoma Research Paper

Sensitive molecular detection of small nodal metastasis in uterine cervical cancer using HPV16-E6/CK19/MUC1 cancer biomarkers Research Paper

High infiltration of CD68+ macrophages is associated with poor prognoses of head and neck squamous cell carcinoma patients and is influenced by human papillomavirus Research Paper

Cis-trimethoxy resveratrol induces intrinsic apoptosis via prometaphase arrest and prolonged CDK1 activation pathway in human Jurkat T cells Research Paper

Progesterone and calcitriol reduce invasive potential of endometrial cancer cells by targeting ARF6, NEDD9 and MT1-MMP Research Paper

Cell death and restoration of TRAIL-sensitivity by ciglitazone in resistant cervical cancer cells Research Paper

Twist1 mediated regulation of glioma tumorigenicity is dependent on mode of mouse neural progenitor transformation Research Paper

Expression characteristics of the plasmid-borne mcr-1 colistin resistance gene Research Paper

Viral E6/E7 oncogene and cellular hexokinase 2 expression in HPV-positive cancer cell lines Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Hypothesis: HPV E6 and COVID spike proteins cooperate in targeting tumor suppression by p53 Hypothesis

NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer Research Paper

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV+ head and neck squamous cell carcinomas Research Paper

Evidence for context-dependent functions of KDM5B in prostate development and prostate cancer Research Paper

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Lactate induces PD-L1 in HRASG12V-positive oropharyngeal squamous cell carcinoma Research Paper

Assessment of circularized E7 RNA, GLUT1, and PD-L1 in anal squamous cell carcinoma Research Paper

Defining molecular risk in ALK+ NSCLC Research Perspective

Phospholipidation of nuclear proteins by the human papillomavirus E6 oncoprotein: implication in carcinogenesis Research Paper

Silencing of casein kinase 1 delta reduces migration and metastasis of triple negative breast cancer cells Research Paper

Viral DNA integration and methylation of human papillomavirus type 16 in high-grade oral epithelial dysplasia and head and neck squamous cell carcinoma Research Paper

Sensitive molecular detection of small nodal metastasis in uterine cervical cancer using HPV16-E6/CK19/MUC1 cancer biomarkers Research Paper

High infiltration of CD68+ macrophages is associated with poor prognoses of head and neck squamous cell carcinoma patients and is influenced by human papillomavirus Research Paper

Cis-trimethoxy resveratrol induces intrinsic apoptosis via prometaphase arrest and prolonged CDK1 activation pathway in human Jurkat T cells Research Paper

Progesterone and calcitriol reduce invasive potential of endometrial cancer cells by targeting ARF6, NEDD9 and MT1-MMP Research Paper

Cell death and restoration of TRAIL-sensitivity by ciglitazone in resistant cervical cancer cells Research Paper

Twist1 mediated regulation of glioma tumorigenicity is dependent on mode of mouse neural progenitor transformation Research Paper

Expression characteristics of the plasmid-borne mcr-1 colistin resistance gene Research Paper

Viral E6/E7 oncogene and cellular hexokinase 2 expression in HPV-positive cancer cell lines Research Paper

A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV⁺ head and neck squamous cell carcinomas Research Paper

Lactate induces PD-L1 in HRAS^G12V-positive oropharyngeal squamous cell carcinoma Research Paper

Defining molecular risk in ALK⁺ NSCLC Research Perspective