Moderate hypofractionation for prostate cancer

Unified promoter opening steps in eukaryotic gene expression

Targeted treatment of advanced NRAS-mutated melanoma

Defining tissue resident vascular stem cells

TRPM2 channels in mitochondrial dynamics and cancer

Multiple arterial grafting and ostriches: let’s all take heart!

New concepts in fulminant myocarditis and risk of cardiac mortality

Molecular regulation of T-ALL cell infiltration into the CNS

New ideas in preventing castration-resistant prostate cancer

BETting on combination to overcome PARPi resistance

Maintenance of elderly AML patients with androgens

CLL kinetics in the tumor microenvironment

Transient targeting of the pancreatic cancer stroma as a ‘fine-tuned’ anti-tumor and anti-metastatic therapy

Chipping in on clonal hematopoiesis

Conditional survival estimates for cancer patients

Discovery of spermatogenic activators: a lesson from bone morphogenetic protein 8

Novel combinations of PI3K-mTOR inhibitors with dacomitinib or chemotherapy in PTEN-deficient patient-derived tumor xenografts

Glioblastoma and glioblastoma stem cells are dependent on functional MTH1

Uncoupling TORC2 from AGC kinases inhibits tumour growth

Overcoming resistance to single-agent therapy for oncogenic BRAF gene fusions via combinatorial targeting of MAPK and PI3K/mTOR signaling pathways

Epigenetic silencing of tumor suppressor candidate 3 confers adverse prognosis in early colorectal cancer

Remote intracranial recurrence of IDH mutant gliomas is associated with TP53 mutations and an 8q gain

Vemurafenib-resistance via de novo RBM genes mutations and chromosome 5 aberrations is overcome by combined therapy with palbociclib in thyroid carcinoma with BRAF^V600E

The histone demethylase Kdm3a is required for normal epithelial proliferation, ductal elongation and tumor growth in the mouse mammary gland

Pharmacologic inhibition of PI3K p110δ in mutant Shp2E76K-expressing mice

A prenatal interruption of DISC1 function in the brain exhibits a lasting impact on adult behaviors, brain metabolism, and interneuron development

Distribution of lymph node metastasis from lymphoepithelial-like carcinoma of the parotid

Frequency of expression and generation of T-cell responses against antigens on multiple myeloma cells in patients included in the GMMG-MM5 trial

Implications of PI3K/AKT inhibition on REST protein stability and neuroendocrine phenotype acquisition in prostate cancer cells

Abnormal amplitude of low-frequency fluctuations associated with rapid-eye movement in chronic primary insomnia patients

Neutrophils in chronic lymphocytic leukemia are permanently activated and have functional defects

Increased transcriptional and metabolic capacity for lipid metabolism in the peripheral zone of the prostate may underpin its increased susceptibility to cancer

CDK3, target of miR-4469, suppresses breast cancer metastasis via inhibiting Wnt/β-catenin pathway

PDAC-derived exosomes enrich the microenvironment in MDSCs in a SMAD4-dependent manner through a new calcium related axis

MiR-2964a-5p binding site SNP regulates ATM expression contributing to age-related cataract risk

Interaction of microRNA-21/145 and Smad3 domain-specific phosphorylation in hepatocellular carcinoma

Exploring brusatol as a new anti-pancreatic cancer adjuvant: biological evaluation and mechanistic studies

Combined BRD4 and CDK9 inhibition as a new therapeutic approach in malignant rhabdoid tumors

Cell-specific regulation of proliferation by Ano1/TMEM16A in breast cancer with different ER, PR, and HER2 status

Linc00152 suppresses apoptosis and promotes migration by sponging miR-4767 in vascular endothelial cells

Association of breast carcinoma growth with a non-canonical axis of IFNγ/IDO1/TSP1

Post-surgery fluids promote transition of cancer stem cell- to-endothelial and AKT/mTOR activity, contributing to relapse of giant cell tumors of bone

Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer

ACKR3 expression on diffuse large B cell lymphoma is required for tumor spreading and tissue infiltration

Upregulation of CD11b and CD86 through LSD1 inhibition promotes myeloid differentiation and suppresses cell proliferation in human monocytic leukemia cells

Mkrn3 functions as a novel ubiquitin E3 ligase to inhibit Nptx1 during puberty initiation

Infradiaphragmatic Hodgkin lymphoma: a large series of patients staged with PET-CT

A preclinical evaluation of the MEK inhibitor refametinib in HER2-positive breast cancer cell lines including those with acquired resistance to trastuzumab or lapatinib

Using molecular functional networks to manifest connections between obesity and obesity-related diseases

The synergistic antitumor effect of cinobufagin and cisplatin in human osteosarcoma cell line in vitro and in vivo

Multiple regulatory aspects of histone methyltransferase EZH2 in Pb-induced neurotoxicity

Radiolabelled polymeric IgA: from biodistribution to a new molecular imaging tool in colorectal cancer lung metastases

The prognostic impact of overall treatment time on disease outcome in uterine cervical cancer patients treated primarily with concomitant chemoradiotherapy: a nationwide Taiwanese cohort study

Investigation of factors affecting the efficacy of 3C23K, a human monoclonal antibody targeting MISIIR

Connective tissue growth factor mediates TGF-β1-induced low-grade serous ovarian tumor cell apoptosis

Using droplet digital PCR to analyze MYCN and ALK copy number in plasma from patients with neuroblastoma

Oligomer procyanidins (F2) repress HIF-1α expression in human U87 glioma cells by inhibiting the EGFR/ AKT/mTOR and MAPK/ERK1/2 signaling pathways in vitro and in vivo

Interleukin-31 and thymic stromal lymphopoietin expression in plasma and lymph node from Hodgkin lymphoma patients

The microRNAs miR-200b-3p and miR-429-5p target the LIMK1/CFL1 pathway to inhibit growth and motility of breast cancer cells

Novel strategies of Raman imaging for brain tumor research

A hemoglobin-based oxygen carrier sensitized Cisplatin based chemotherapy in hepatocellular carcinoma

Whole-exome sequencing reveals novel mutations and epigenetic regulation in hypopharyngeal carcinoma

Effects of pharmacological gap junction and sodium channel blockade on S1S2 restitution properties in Langendorff-perfused mouse hearts

lncRNA PVT1 and its splicing variant function as competing endogenous RNA to regulate clear cell renal cell carcinoma progression

Methylation of CpG sites in the upstream regulatory region, physical status and mRNA expression of HPV-6 in adult-onset laryngeal papilloma

Adiponectin receptor agonists inhibit leptin induced pSTAT3 and in vivo pancreatic tumor growth

Bone marrow IRF4 level in multiple myeloma: an indicator of peripheral blood Th17 and disease

Long non-coding RNA HOTAIR acts as a competing endogenous RNA to promote malignant melanoma progression by sponging miR-152-3p

A RasGAP, DAB2IP, regulates lipid droplet homeostasis by serving as GAP toward RAB40C

Generation of patient specific human neural stem cells from Niemann-Pick disease type C patient-derived fibroblasts

miR-21 modulates the effect of EZH2 on the biological behavior of human lung cancer stem cells in vitro

Dietary inflammatory index and the risk of gastric cancer in a Korean population

An integrated lncRNA, microRNA and mRNA signature to improve prognosis prediction of colorectal cancer

PAX3d mRNA over 2.76 copies/μL in the bloodstream predicts cutaneous malignant melanoma relapse

Telomerase reverse transcriptase mediates EMT through NF-κB signaling in tongue squamous cell carcinoma

Effects of sodium fluoride on blood cellular and humoral immunity in mice

Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model

Impact of mismatch-repair deficiency on the colorectal cancer immune microenvironment

Electroacupuncture alleviates neuromuscular dysfunction in an experimental rat model of immobilization

Improvement of therapeutic effects of mesenchymal stem cells in myocardial infarction through genetic suppression of microRNA-142

Screening epitopes on systemic lupus erythematosus autoantigens with a peptide array

PRMDA: personalized recommendation-based MiRNA-disease association prediction

Hepatitis C virus Core overcomes all-trans retinoic acid-induced apoptosis in human hepatoma cells by inhibiting p14 expression via DNA methylation

Changes of alpha-fetoprotein levels could predict recurrent hepatocellular carcinoma survival after trans-arterial chemoembolization

Predictive value of preoperative inflammatory response biomarkers for metabolic syndrome and post-PCNL systemic inflammatory response syndrome in patients with nephrolithiasis

TSSC3 represses self-renewal of osteosarcoma stem cells and Nanog expression by inhibiting the Src/Akt pathway

Lethality of inappropriate plasma exposure on chicken embryonic development

Association of melatonin membrane receptor 1A/1B gene polymorphisms with the occurrence and metastasis of hepatocellular carcinoma

High uric acid (UA) downregulates bone alkaline phosphatase (BALP) expression through inhibition of its promoter activity

Somatic mutations in CDH1 and CTNNB1 in primary carcinomas at 13 anatomic sites

Identification of potential tissue-specific cancer biomarkers and development of cancer versus normal genomic classifiers

Early and late effects of aspirin and naproxen on microRNAs in the lung and blood of mice, either unexposed or exposed to cigarette smoke

Candidate tumor suppressor ZNF154 suppresses invasion and metastasis in NPC by inhibiting the EMT via Wnt/β-catenin signalling

Functional characterization of a novel transcript of ERCC1 in chemotherapy resistance of ovarian cancer

Escherichia coli Nissle 1917 engineered to express Tum-5 can restrain murine melanoma growth

MiR-221-regulated KIT level by wild type or leukemia mutant RUNX1: a determinant of single myeloblast fate decisions that – collectively – drives or hinders granulopoiesis

A PTEN-COL17A1 fusion gene and its novel regulatory role in Collagen XVII expression and GBM malignance

Development of novel long noncoding RNA MALAT1 near-infrared optical probes for in vivo tumour imaging

Smoking and gender modify the effect of TWIST on patient survival in head and neck squamous carcinoma

MicroRNA-29a increased the intestinal membrane permeability of colonic epithelial cells in irritable bowel syndrome rats

Extracts from Hericium erinaceus relieve inflammatory bowel disease by regulating immunity and gut microbiota

Glutaminase inhibition in multiple myeloma induces apoptosis via MYC degradation

ELAS1 induces apoptotic death in adenocarcinoma DU145 and squamous-cell carcinoma SAS cancer cells, but not in normal KD cells

The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation

Network-directed cis-mediator analysis of normal prostate tissue expression profiles reveals downstream regulatory associations of prostate cancer susceptibility loci

Isobaric tags for relative and absolute quantification-based proteomic analysis of testis biopsies in rhesus monkeys treated with transient scrotal hyperthermia

Enhancing conventional chemotherapy drug cisplatin-induced anti-tumor effects on human gastric cancer cells both in vitro and in vivo by Thymoquinone targeting PTEN gene

Clinical significance of pre-surgical serum lipid levels in patients with glioblastoma

Liraglutide activates autophagy via GLP-1R to improve functional recovery after spinal cord injury

SCO-spondin oligopeptide inhibits angiogenesis in glioblastoma

Novel post-transcriptional and post-translational regulation of pro-apoptotic protein BOK and anti-apoptotic protein Mcl-1 determine the fate of breast cancer cells to survive or die

STAT3 and STAT5A are potential therapeutic targets in castration-resistant prostate cancer

Association of ACYP2 and MPHOSPH6 genetic polymorphisms with the risk of hepatocellular carcinoma in chronic hepatitis B virus carriers

MicroRNAs as predictors for CNS relapse of systemic diffuse large B-cell lymphoma

Monophosphoryl lipid a attenuates radiation injury through TLR4 activation

UCHL1 expression and localization on testicular development and spermatogenesis of Chinese giant salamanders

Patients with NSCLC may display a low ratio of p.T790M vs. activating EGFR mutations in plasma at disease progression: implications for personalised treatment

Worse disease-free, tumor-specific, and overall survival in surgically-resected lung adenocarcinoma patients with ALK rearrangement

Selecting lncRNAs in gastric cancer cells for directed therapy with bioactive peptides and chemotherapy drugs

Baicalein inhibits progression of osteosarcoma cells through inactivation of the Wnt/β-catenin signaling pathway

Toxoplasma gondii Clp family protein: TgClpB1 plays a crucial role in thermotolerance

Trends in neoadjuvant chemotherapy use and oncological outcomes for muscle-invasive bladder cancer in Japan: a multicenter study

Isolation of circulating tumor cells from pancreatic cancer by automated filtration

Marital status and survival of patients with kidney cancer

In silico and in vitro identification of inhibitory activities of sorafenib on histone deacetylases in hepatocellular carcinoma cells

Suicidal ideation among Chinese methadone-maintained patients: prevalence and correlates

Natural compound bavachalcone promotes the differentiation of endothelial progenitor cells and neovascularization through the RORα-erythropoietin-AMPK axis

Modulation of HIF-1α and STAT3 signaling contributes to anti-angiogenic effect of YC-1 in mice with liver fibrosis

XRCC1 mediated the development of cervival cancer through a novel Sp1/Krox-20 swich

Kaempferol induces autophagic cell death of hepatocellular carcinoma cells via activating AMPK signaling

The relationship between stromal cell derived SPARC in human gastric cancer tissue and its clinicopathologic significance

Liquid biopsy in colon cancer: comparison of different circulating DNA extraction systems following absolute quantification of KRAS mutations using Intplex allele-specific PCR

Methylation of microRNA-129-5P modulates nucleus pulposus cell autophagy by targeting Beclin-1 in intervertebral disc degeneration

Salen-Mn compounds induces cell apoptosis in human prostate cancer cells through promoting AMPK activity and cell autophagy

Prognostic evaluation of platelet to lymphocyte ratio in patients with colorectal cancer

Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability

JQ1 synergizes with the Bcl-2 inhibitor ABT-263 against MYCN-amplified small cell lung cancer

ARHI is a novel epigenetic silenced tumor suppressor in sporadic pheochromocytoma

Asiatic acid protects against hepatic ischemia/reperfusion injury by inactivation of Kupffer cells via PPARγ/NLRP3 inflammasome signaling pathway

Comparative molecular analyses of left-sided colon, right-sided colon, and rectal cancers

Genomic characterization of human papillomavirus-positive and -negative human squamous cell cancer cell lines

Efficacy and safety of first-line pemetrexed plus carboplatin followed by single-agent pemetrexed maintenance in elderly Chinese patients with non-squamous non-small-cell lung cancer

TET1 inhibits cell proliferation by inducing RASSF5 expression

HOTAIR regulates HK2 expression by binding endogenous miR-125 and miR-143 in oesophageal squamous cell carcinoma progression

Circulating tumor DNA shows variable clonal response of breast cancer during neoadjuvant chemotherapy

Association between SNPs in microRNA machinery genes and gastric cancer susceptibility, invasion, and metastasis in Chinese Han population

Halofuginone inhibits TGF-β/BMP signaling and in combination with zoledronic acid enhances inhibition of breast cancer bone metastasis

Serum hepatitis B surface antigen levels predict insignificant fibrosis and non-cirrhosis in hepatitis B e antigen positive patients with normal or mildly elevated alanine transaminase levels

Adipose-derived stem cells-seeded bladder acellular matrix graft-silk fibroin enhances bladder reconstruction in a rat model

PSC-derived Galectin-1 inducing epithelial-mesenchymal transition of pancreatic ductal adenocarcinoma cells by activating the NF-κB pathway

FcGBP was upregulated by HPV infection and correlated to longer survival time of HNSCC patients

Correlation of DRD2 mRNA expression levels with deficit syndrome severity in chronic schizophrenia patients receiving clozapine treatment

Association of variant in the ADIPOQ gene and functional study for its role in atherosclerosis

Screening circular RNA expression patterns following focal cerebral ischemia in mice

The effect of aspirin on circulating netrin-1 levels in humans is dependent on the inflammatory status of the vascular endothelium

Mixed subtype thyroid cancer: A surveillance, epidemiology, and end results database analysis

Near-infrared photothermal therapy using anti-EGFR-gold nanorod conjugates for triple negative breast cancer

A plasmid containing CpG ODN as vaccine adjuvant against grass carp reovirus in grass carp Ctenopharyngodon idella

miR-29a-3p suppresses cell proliferation and migration by downregulating IGF1R in hepatocellular carcinoma

A water-soluble polysaccharide from Grifola frondosa induced macrophages activation via TLR4-MyD88-IKKβ-NF-κB p65 pathways

Prognostic significance of circulating tumor cells in non-small cell lung cancer patients undergoing chemotherapy

Circular RNA expression profiles reveal that hsa_circ_0018289 is up-regulated in cervical cancer and promotes the tumorigenesis

Differential activation of Fyn kinase distinguishes saturated and unsaturated fats in mouse macrophages

37 kDa LRP::FLAG enhances telomerase activity and reduces senescent markers in vitro

Targeting P-selectin blocks neuroblastoma growth

Protective effect of Ginkgo biloba leaves extract, EGb761, on myocardium injury in ischemia reperfusion rats via regulation of TLR-4/NF-κB signaling pathway

Hepatitis C virus core protein potentiates proangiogenic activity of hepatocellular carcinoma cells

The β-glucan from Lentinus edodes suppresses cell proliferation and promotes apoptosis in estrogen receptor positive breast cancers

MDM4 genetic variants predict HPV16-positive tumors of patients with squamous cell carcinoma of the oropharynx

FBN3 gene involved in pathogenesis of a Chinese family with Bardet-Biedl syndrome

Protective effect of NSA on intestinal epithelial cells in a necroptosis model

Associations of high altitude polycythemia with polymorphisms in EPAS1, ITGA6 and ERBB4 in Chinese Han and Tibetan populations

Targeting aggressive prostate cancer-associated CD44v6 using phage display selected peptides

Oncolytic reovirus inhibits angiogenesis through induction of CXCL10/IP-10 and abrogation of HIF activity in soft tissue sarcomas

Indonesian herbal medicine prevents hypertension-induced left ventricular hypertrophy by diminishing NADPH oxidase-dependent oxidative stress

The role of Rak in the regulation of stability and function of BRCA1

Associations between dietary folate intake and risks of esophageal, gastric and pancreatic cancers: an overall and dose-response meta-analysis

The benefit of immunonutrition in patients undergoing hepatectomy: a systematic review and meta-analysis

Association between CYP2E1 genetic polymorphisms and urinary cancer risk: a meta-analysis

Efficacy of intra-articular hyaluronic acid injections in hip osteoarthritis: a meta-analysis of randomized controlled trials

Associations between EGFR gene polymorphisms and susceptibility to glioma: a systematic review and meta-analysis from GWAS and case-control studies

A three-microRNA signature for lung squamous cell carcinoma diagnosis in Chinese male patients

Metastatic to negative lymph node ratio demonstrates significant prognostic value in patients with esophageal squamous cell carcinoma after esophagectomy

S100A14 rs11548103 G>A polymorphism is associated with a decreased risk of esophageal cancer in a Chinese population

Longitudinal relationship between traumatic brain injury and the risk of incident optic neuropathy: A 10-year follow-up nationally representative Taiwan survey

Nomograms for prognostic factors of spinal giant cell tumor combining traditional clinical characteristics with inflammatory biomarkers after gross total resection

Harness the synergy between targeted therapy and immunotherapy: what have we learned and where are we headed?