GNP-GAPDH_1-22 nanovaccines prevent neonatal listeriosis by blocking microglial apoptosis and bacterial dissemination

SNX10 promotes phagosome maturation in macrophages and protects mice against Listeria monocytogenes infection

Risk assessment models for genetic risk predictors of lung cancer using two-stage replication for Asian and European populations

MDM2 antagonists synergize with PI3K/mTOR inhibition in well-differentiated/dedifferentiated liposarcomas

PD-L1 and c-MET expression and survival in patients with small cell lung cancer

MYC-dependent recruitment of RUNX1 and GATA2 on the SET oncogene promoter enhances PP2A inactivation in acute myeloid leukemia

Loss of giant obscurins alters breast epithelial cell mechanosensing of matrix stiffness

E2F3 upregulation promotes tumor malignancy through the transcriptional activation of HIF-2α in clear cell renal cell carcinoma

Alu–based cell-free DNA: a novel biomarker for screening of gastric cancer

Evaluation of a community-based integrated heroin addiction treatment model in Chinese patients

The pancreatic tumor microenvironment drives changes in miRNA expression that promote cytokine production and inhibit migration by the tumor associated stroma

The PWWP domain of the human oncogene WHSC1L1/NSD3 induces a metabolic shift toward fermentation

CXCL12/CXCR4 pathway is activated by oncogenic JAK2 in a PI3K-dependent manner

Distinct clinicopathological features in metanephric adenoma harboring BRAF mutation

Pericardial effusion is correlated with clinical outcome after pulmonary artery denervation for pulmonary arterial hypertension

CD164 promotes lung tumor-initiating cells with stem cell activity and determines tumor growth and drug resistance via Akt/mTOR signaling

Fractalkine/CX3CL1 induced intercellular adhesion molecule-1-dependent tumor metastasis through the CX3CR1/PI3K/Akt/NF-κB pathway in human osteosarcoma

Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines in vitro and AKT-driven hepatocarcinogenesis in mice

The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status

Myeloid-derived suppressor cell and macrophage exert distinct angiogenic and immunosuppressive effects in breast cancer

Effect of PKC inhibitor on experimental autoimmune myocarditis in Lewis rats

Base excision repair imbalance in colorectal cancer has prognostic value and modulates response to chemotherapy

Sodium selenite prevents suppression of mucosal humoral response by AFB₁ in broiler’s cecal tonsil

G protein-coupled receptor kinase 6 is overexpressed in glioma and promotes glioma cell proliferation

Targeting the apoptotic Mcl-1-PUMA interface with a dual-acting compound

TLR2 activation induces antioxidant defence in human monocyte-macrophage cell line models

ING5 knockdown enhances migration and invasion of lung cancer cells by inducing EMT via EGFR/PI3K/Akt and IL-6/STAT3 signaling pathways

Multi-modality imaging-monitored creation of rat orthotopic pancreatic head cancer with obstructive jaundice

APOBEC3G acts as a therapeutic target in mesenchymal gliomas by sensitizing cells to radiation-induced cell death

Patients with chronic lymphocytic leukemia and complex karyotype show an adverse outcome even in absence of TP53/ATM FISH deletions

A study on the anti-tumor mechanism of total flavonoids from Radix Tetrastigmae against additional cell line based on COX-2-mediated Wnt/β-catenin signaling pathway

Establishing a patient-derived xenograft model of human myxoid and round-cell liposarcoma

Profiling of metastatic small intestine neuroendocrine tumors reveals characteristic miRNAs detectable in plasma

Glutathione peroxidase 7 suppresses cancer cell growth and is hypermethylated in gastric cancer

Retrospective analysis of risk factors associated with Kawasaki disease in China

Nuclear receptor NR4A1 is a tumor suppressor down-regulated in triple-negative breast cancer

The G-protein-coupled bile acid receptor Gpbar1 (TGR5) protects against renal inflammation and renal cancer cell proliferation and migration through antagonizing NF-κB and STAT3 signaling pathways

ZEB1 confers stem cell-like properties in breast cancer by targeting neurogenin-3

Preoperative transcatheter arterial chemotherapy may suppress oxidative stress in hepatocellular carcinoma cells and reduce the risk of short-term relapse

Analysis of Bos taurus and Sus scrofa X and Y chromosome transcriptome highlights reproductive driver genes

Direct inhibition of STAT signaling by platinum drugs contributes to their anti-cancer activity

HER2 isoforms co-expression differently tunes mammary tumor phenotypes affecting onset, vasculature and therapeutic response

Anti-proliferative, pro-apoptotic and anti-invasive effect of EC/EV system in human osteosarcoma

Sexual life satisfaction and its associated socio-demographic and workplace factors among Chinese female nurses of tertiary general hospitals

Intratumoral acidosis fosters cancer-induced bone pain through the activation of the mesenchymal tumor-associated stroma in bone metastasis from breast carcinoma

MRI-based radiotherapy planning method using rigid image registration technique combined with outer body correction scheme: a feasibility study

Expression of sialyl-Tn sugar antigen in bladder cancer cells affects response to Bacillus Calmette Guérin (BCG) and to oxidative damage

Variants in the CXCL12 gene was associated with coronary artery disease susceptibility in Chinese Han population

Fulvestrant 500 milligrams as endocrine therapy for endocrine sensitive advanced breast cancer patients in the real world: the Ful500 prospective observational trial

Cell-free circulating DNA integrity is an independent predictor of impending breast cancer recurrence

P53 prevent tumor invasion and metastasis by down-regulating IDO in lung cancer

KIF7 attenuates prostate tumor growth through LKB1-mediated AKT inhibition

Protective effects of circulating microvesicles derived from myocardial ischemic rats on apoptosis of cardiomyocytes in myocardial ischemia/reperfusion injury

Systematic analysis of coronary artery disease datasets revealed the potential biomarker and treatment target

Exploratory investigation of PSCA-protein expression in primary breast cancer patients reveals a link to HER2/neu overexpression

Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer

Toxicology and efficacy of tumor-targeting Salmonella typhimurium A1-R compared to VNP 20009 in a syngeneic mouse tumor model in immunocompetent mice

Human mesenchymal stem cells preferentially migrate toward highly oncogenic human hepatocellular carcinoma cells with activated EpCAM signaling

Sociodemographic and economic factors are associated with weight gain between before and after cancer diagnosis: results from the prospective population-based NutriNet-Santé cohort

Myosin Va plays essential roles in maintaining normal mitosis, enhancing tumor cell motility and viability

Pre-operative to post-operative serum carcinoembryonic antigen ratio is a prognostic indicator in colorectal cancer

Resveratrol enhances polyubiquitination-mediated ARV7 degradation in prostate cancer cells

Transcription factor Yin Yang 2 is a novel regulator of the p53/p21 axis

Improving circulating tumor cells enumeration and characterization to predict outcome in first line chemotherapy mCRPC patients

PD-L1/PD-1 expression and tumor-infiltrating lymphocytes in conjunctival melanoma

AGO2 involves the malignant phenotypes and FAK/PI3K/AKT signaling pathway in hypopharyngeal-derived FaDu cells

Extracorporeal shock wave treatment attenuated left ventricular dysfunction and remodeling in mini-pig with cardiorenal syndrome

Mex3a expression and survival analysis of bladder urothelial carcinoma

Tumor location impacts immune response in mouse models of colon cancer

MicroRNA16 regulates glioma cell proliferation, apoptosis and invasion by targeting Wip1-ATM-p53 feedback loop

Association between ABO blood types and sporadic pancreatic neuroendocrine tumors in the Chinese Han population

A novel SHARPIN-PRMT5-H3R2me1 axis is essential for lung cancer cell invasion

DPP-4 enzyme deficiency protects kidney from acute ischemia-reperfusion injury: role for remote intermittent bowel ischemia-reperfusion preconditioning

Synergistic inhibition of colon cancer growth by the combination of methylglyoxal and silencing of glyoxalase I mediated by the STAT1 pathway

Hyperactivated mTORC1 downregulation of FOXO3a/PDGFRα/AKT cascade restrains tuberous sclerosis complex-associated tumor development

Cancer-associated mutations in the canonical cleavage site do not influence CD99 shedding by the metalloprotease meprin β but alter cell migration in vitro

Epithelial HO-1/STAT3 affords the protection of subanesthetic isoflurane against zymosan-induced lung injury in mice

Association between the functional polymorphism Ile31Phe in the AURKA gene and susceptibility of hepatocellular carcinoma in chronic hepatitis B virus carriers

Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK

A role for BRG1 in the regulation of genes required for development of the lymphatic system

EB1 protein alteration characterizes sporadic but not ulcerative colitis associated colorectal cancer

Melittin suppresses tumor progression by regulating tumor-associated macrophages in a Lewis lung carcinoma mouse model

TGF-β2-induced ANGPTL4 expression promotes tumor progression and osteoclast differentiation in giant cell tumor of bone

IGFBP2 plays an important role in heat shock protein 27-mediated cancer progression and metastasis

DlgR2 knockdown boosts dendritic cell activity and inhibits hepatocellular carcinoma tumor in-situ growth

New perspectives of cobalt tris(bipyridine) system: anti-cancer effect and its collateral sensitivity towards multidrug-resistant (MDR) cancers

Phosphatidylcholine-specific phospholipase C inhibition reduces HER2-overexpression, cell proliferation and in vivo tumor growth in a highly tumorigenic ovarian cancer model

Hyperglycemia and advanced glycation end products (AGEs) suppress the differentiation of 3T3-L1 preadipocytes

7-deacetylgedunin suppresses inflammatory responses through activation of Keap1/Nrf2/HO-1 signaling

Impact of chronic methamphetamine treatment on the atherosclerosis formation in ApoE−/− mice fed a high cholesterol diet

Cofilin-1 and phosphoglycerate kinase 1 as promising indicators for glioma radiosensibility and prognosis

Tumor-specific hepatic stellate cells (tHSCs) induces DIgR2 expression in dendritic cells to inhibit T cells

Uptake of PSMA-ligands in normal tissues is dependent on tumor load in patients with prostate cancer

Presence of Salmonella AvrA in colorectal tumor and its precursor lesions in mouse intestine and human specimens

miR-331-3p and Aurora Kinase inhibitor II co-treatment suppresses prostate cancer tumorigenesis and progression

Derlin-1 is a target to improve radiotherapy effect of esophageal squamous cell carcinoma

Acetyl-lupeolic acid inhibits Akt signaling and induces apoptosis in chemoresistant prostate cancer cells in vitro and in vivo

RASSF6 downregulation promotes the epithelial-mesenchymal transition and predicts poor prognosis in colorectal cancer

Efficacy and safety of Re-Du-Ning injection in the treatment of seasonal influenza: results from a randomized, double-blinded, multicenter, oseltamivir-controlled trial

Acute atorvastatin treatment restores the cardioprotective effects of ischemic postconditioning in hyperlipidemic rats

A novel heterozygous germline deletion in MSH2 gene in a five generation Chinese family with Lynch syndrome

Micro-HCCs in rats with liver cirrhosis: paradoxical targeting effects with vascular disrupting agent CA4P

A missense mutation in TCN2 is associated with decreased risk for congenital heart defects and may increase cellular uptake of vitamin B12 via Megalin

Overriding TKI resistance of renal cell carcinoma by combination therapy with IL-6 receptor blockade

Disruption of DNA repair in cancer cells by ubiquitination of a destabilising dimerization domain of nucleotide excision repair protein ERCC1

Histone modification alteration coordinated with acquisition of promoter DNA methylation during Epstein-Barr virus infection

Development of zebrafish medulloblastoma-like PNET model by TALEN-mediated somatic gene inactivation

High expression of Ki-67 is an independent favorable prognostic factor for esophageal small cell carcinoma

Development and validation of a preoperative prediction model for colorectal cancer T-staging based on MDCT images and clinical information

CDK4/6 inhibition is more active against the glioblastoma proneural subtype

Mitochondria sustain store-operated currents in colon cancer cells but not in normal colonic cells: reversal by non-steroidal anti-inflammatory drugs

Identification and characterization of a novel SCYL3-NTRK1 rearrangement in a colorectal cancer patient

Pasireotide is more effective than octreotide, alone or combined with everolimus on human meningioma in vitro

The prognostic implication of intraductal carcinoma of the prostate in metastatic castration-resistant prostate cancer and its potential predictive value in those treated with docetaxel or abiraterone as first-line therapy

Ginsenoside Rg1 attenuates adjuvant-induced arthritis in rats via modulation of PPAR-γ/NF-κB signal pathway

Comparison of clinical utilities of the platelet count and platelet-lymphocyte ratio for predicting survival in patients with cervical cancer: a single institutional study and literature review

Lenalidomide restores the osteogenic differentiation of bone marrow mesenchymal stem cells from multiple myeloma patients via deactivating Notch signaling pathway

Resveratrol inhibits age-dependent spontaneous tumorigenesis by SIRT1-mediated post-translational modulations in the annual fish Nothobranchius guentheri

Detection of specific Chlamydia pneumoniae and cytomegalovirus antigens in human carotid atherosclerotic plaque in a Chinese population

Genetic variation and forensic characteristic analysis of 25 STRs of a novel fluorescence co-amplification system in Chinese Southern Shaanxi Han population

microRNA-451-modulated hnRNP A1 takes a part in granulocytic differentiation regulation and acute myeloid leukemia

Effects of metformin on survival outcomes of pancreatic cancer: a meta-analysis

Prognostic value of microRNAs in gastric cancer: a meta-analysis

Meta-analysis of microRNAs expression in head and neck cancer: uncovering association with outcome and mechanisms

Lymph node status in different molecular subtype of breast cancer: triple negative tumours are more likely lymph node negative

Evaluation of pituitary uptake incidentally identified on 18F-FDG PET/CT scan

Loss of steroid hormone receptors is common in malignant pleural and peritoneal effusions of breast cancer patients treated with endocrine therapy

Association between coronary heart disease and erectile dysfunction in Chinese Han population

Radioligand therapy of metastatic prostate cancer using ¹⁷⁷Lu-PSMA-617 after radiation exposure to ²²³Ra-dichloride

Early tumour shrinkage as a survival predictor in patients with recurrent glioblastoma treated with bevacizumab in the AVAREG randomized phase II study

Predicting clinical benefit from everolimus in patients with advanced solid tumors, the CPCT-03 study

Application of embolization microspheres in interventional therapy of malignant non-hypervascular tumor of liver

Locoregionally recurrent head and neck squamous cell carcinoma: incidence, survival, prognostic factors, and treatment outcomes

Association between metformin and the risk of gastric cancer in patients with type 2 diabetes mellitus: a meta-analysis of cohort studies

Clinical and biological significance of circulating tumor cells, circulating tumor DNA, and exosomes as biomarkers in colorectal cancer

The correlation of sperm morphology with unexplained recurrent spontaneous abortion: A systematic review and meta-analysis

Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival for peritoneal carcinomatosis from colorectal cancer: a systematic review and meta-analysis of current evidence

The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells

Precision medicine for hepatocellular carcinoma: driver mutations and targeted therapy

Targeting EIF4F complex in non-small cell lung cancer cells

Tumor reductive therapies and antitumor immunity

The lifecycle of the Ebola virus in host cells

Correction: Increased expression of SKP2 is an independent predictor of locoregional recurrence in cervical cancer via promoting DNA-damage response after irradiation