Defining the transcriptional and biological response to CDK4/6 inhibition in relation to ER+/HER2- breast cancer

Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model

Native and bone marrow-derived cell mosaicism in gastric carcinoma in H. pylori-infected p27-deficient mice

Targeting the ERK pathway for the treatment of Cushing’s disease

RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation

IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance

Reduced bone resorption by intake of dietary vitamin D and K from tailor-made Atlantic salmon: a randomized intervention trial

The effect of the severity of obstructive sleep apnea syndrome on telomere length

INPP5D rs35349669 polymorphism with late-onset Alzheimer’s disease: A replication study and meta-analysis

Nitric oxide, PKC-ε, and connexin43 are crucial for ischemic preconditioning-induced chemical gap junction uncoupling

Delineation of the central melanocortin circuitry controlling the kidneys by a virally mediated transsynaptic tracing study in transgenic mouse model

Frequent somatic TERT promoter mutations and CTNNB1 mutations in hepatocellular carcinoma

Signaling through hepatocyte vasopressin receptor 1 protects mouse liver from ischemia-reperfusion injury

Pharmacological targeting of BET proteins inhibits renal fibroblast activation and alleviates renal fibrosis

Overexpressed cyclophilin B suppresses aldosterone-induced proximal tubular cell injury both in vitro and in vivo

SIRT3 is attenuated in systemic sclerosis skin and lungs, and its pharmacologic activation mitigates organ fibrosis

Movement deficits and neuronal loss in basal ganglia in TRPC1 deficient mice

Nucleoside 5’-O-monophosphorothioates as modulators of the P2Y14 receptor and mast cell degranulation

Blocking TCR restimulation induced necroptosis in adoptively transferred T cells improves tumor control

Implication of NPM1 phosphorylation and preclinical evaluation of the nucleoprotein antagonist N6L in prostate cancer

Imatinib dose escalation versus sunitinib as a second line treatment in KIT exon 11 mutated GIST: a retrospective analysis

Novel antibody probes for the characterization of endosialin/TEM-1

TNFSF15 suppresses VEGF production in endothelial cells by stimulating miR-29b expression via activation of JNK-GATA3 signals

Oncogenic function and clinical implications of SLC3A2-NRG1 fusion in invasive mucinous adenocarcinoma of the lung

GBM-associated mutations and altered protein expression are more common in young patients

Important role of kallikrein 6 for the development of keratinocyte proliferative resistance to topical glucocorticoids

Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma

Circulating tumor cells: A promising marker of predicting tumor response in rectal cancer patients receiving neoadjuvant chemo-radiation therapy

Targeting hexokinase 2 enhances response to radio-chemotherapy in glioblastoma

MXD1 localizes in the nucleolus, binds UBF and impairs rRNA synthesis

The dominant-negative interplay between p53, p63 and p73: A family affair

Urokinase-type plasminogen activator receptor promotes proliferation and invasion with reduced cisplatin sensitivity in malignant mesothelioma

Epigenome-wide association study of smoking and DNA methylation in non-small cell lung neoplasms

EPRS is a critical regulator of cell proliferation and estrogen signaling in ER⁺ breast cancer

Assessment of bevacizumab resistance increased by expression of BCAT1 in IDH1 wild-type glioblastoma: application of DSC perfusion MR imaging

A panel of 13-miRNA signature as a potential biomarker for predicting survival in pancreatic cancer

The pathophysiological significance of PPM1D and therapeutic targeting of PPM1D-mediated signaling by GSK2830371 in mantle cell lymphoma

Mutational burdens and evolutionary ages of thyroid follicular adenoma are comparable to those of follicular carcinoma

CDCP1 is a novel marker of the most aggressive human triple-negative breast cancers

Prognostic significance of osteopontin expression in gastric cancer: a meta-analysis

DOT1L promotes angiogenesis through cooperative regulation of VEGFR2 with ETS-1

The putative oncotarget CSN5 controls a transcription-uncorrelated p53-mediated autophagy implicated in cancer cell survival under curcumin treatment

Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer

Toxicological and efficacy assessment of post-transition metal (Indium) phthalocyanine for photodynamic therapy in neuroblastoma

Nestin suppression attenuates invasive potential of endometrial cancer cells by downregulating TGF-β signaling pathway

Programmed death-ligand 1 is upregulated in intrahepatic lymphoepithelioma-like cholangiocarcinoma

Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation

Rottlerin inhibits cell growth and invasion via down-regulation of Cdc20 in glioma cells

iOri-Human: identify human origin of replication by incorporating dinucleotide physicochemical properties into pseudo nucleotide composition

A simple selection-free method for detecting disseminated tumor cells (DTCs) in murine bone marrow

Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras

Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition

Evidence that vitronectin is a potent migration-enhancing factor for cancer cells chaperoned by fibrinogen: a novel view of the metastasis of cancer cells to low-fibrinogen lymphatics and body cavities

Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer

Subpathway-LNCE: Identify dysfunctional subpathways competitively regulated by lncRNAs through integrating lncRNA-mRNA expression profile and pathway topologies

Cadherin-6 type 2, K-cadherin (CDH6) is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface

Epithelial-mesenchymal transition and nuclear β-catenin induced by conditional intestinal disruption of Cdh1 with Apc is E-cadherin EC1 domain dependent

Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers

Evaluating clinical and prognostic implications of Glypican-3 in hepatocellular carcinoma

SMAD4 loss enables EGF, TGFβ1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells

Identification of Bisindolylmaleimide IX as a potential agent to treat drug-resistant BCR-ABL positive leukemia

Preclinical investigation of ibrutinib, a Bruton’s kinase tyrosine (Btk) inhibitor, in suppressing glioma tumorigenesis and stem cell phenotypes

Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer

A three-gene signature for prognosis in patients with MGMT promoter-methylated glioblastoma

Acquired resistance to venetoclax (ABT-199) in t(14;18) positive lymphoma cells

ABCB1 and ABCC11 confer resistance to eribulin in breast cancer cell lines

Targeting Notch signaling as a novel therapy for retinoblastoma

Paraoxonase 3 inhibits cell proliferation and serves as a prognostic predictor in hepatocellular carcinoma

miR-204 suppresses the development and progression of human glioblastoma by targeting ATF2

Meta-analysis comparing chewing gum versus standard postoperative care after colorectal resection

FRMD6 inhibits human glioblastoma growth and progression by negatively regulating activity of receptor tyrosine kinases

Gemcitabine inhibits immune escape of pancreatic cancer by down regulating the soluble ULBP2 protein

Secondary nuclear targeting of mesoporous silica nano-particles for cancer-specific drug delivery based on charge inversion

BRCA mutations and survival in breast cancer: an updated systematic review and meta-analysis

Efficacy of D5F3 IHC for detecting ALK gene rearrangement in NSCLC patients: a systematic review and meta-analysis

Interferon-stimulated gene 15 induces cancer cell death by suppressing the NF-κB signaling pathway

Nodal signaling promotes vasculogenic mimicry formation in breast cancer via the Smad2/3 pathway

A dose increased once-weekly bortezomib-based combination therapy for multiple myeloma

MMP-1 promoter polymorphism is associated with risk of radiation-induced lung injury in lung cancer patients treated with radiotherapy

A meta-analysis of weekly cisplatin versus three weekly cisplatin chemotherapy plus concurrent radiotherapy (CRT) for advanced head and neck cancer (HNC)

MicroRNA-552 enhances metastatic capacity of colorectal cancer cells by targeting a disintegrin and metalloprotease 28

SPARC expression in gastric cancer predicts poor prognosis: Results from a clinical cohort, pooled analysis and GSEA assay

CpG-induced antitumor immunity requires IL-12 in expansion of effector cells and down-regulation of PD-1

Endothelin-1 promotes epithelial–mesenchymal transition in human chondrosarcoma cells by repressing miR-300

IL-24 modulates the high mobility group (HMG) A1/miR222 /AKT signaling in lung cancer cells

Pre-existing mutations related to tenofovir in chronic hepatitis B patients with long-term nucleos(t)ide analogue drugs treatment by ultra-deep pyrosequencing

Polyphyllin G induce apoptosis and autophagy in human nasopharyngeal cancer cells by modulation of AKT and mitogen-activated protein kinase pathways in vitro and in vivo

The clock gene PER1 plays an important role in regulating the clock gene network in human oral squamous cell carcinoma cells

NTS/NTR1 co-expression enhances epithelial-to-mesenchymal transition and promotes tumor metastasis by activating the Wnt/β-catenin signaling pathway in hepatocellular carcinoma

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication

Oncogenic activation of FAK drives apoptosis suppression in a 3D-culture model of breast cancer initiation

Pathologic heterogeneity of lung adenocarcinomas: A novel pathologic index predicts survival

Induction of epithelial-mesenchymal transition (EMT) by Beclin 1 knockdown via posttranscriptional upregulation of ZEB1 in thyroid cancer cells

Dickkopf-1 expression is associated with tumorigenity and lymphatic metastasis in human hilar cholangiocarcinoma

Novel tumor suppressor microRNA at frequently deleted chromosomal region 8p21 regulates Epidermal Growth Factor Receptor in prostate cancer

Androgen receptor differentially regulates the proliferation of prostatic epithelial cells in vitro and in vivo

Loss of ZNF32 augments the regeneration of nervous lateral line system through negative regulation of SOX2 transcription

Zanthoxylum fruit extract from Japanese pepper promotes autophagic cell death in cancer cells

A vicious cycle between acid sensing and survival signaling in myeloma cells: acid-induced epigenetic alteration

A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice

RTEL1 polymorphisms are associated with lung cancer risk in the Chinese Han population

Identification of the APC/C co-factor FZR1 as a novel therapeutic target for multiple myeloma

COL3A1 and SNAP91: novel glioblastoma markers with diagnostic and prognostic value

Shikonin potentiates the effect of arsenic trioxide against human hepatocellular carcinoma in vitro and in vivo

Analysis of the variability among radiation oncologists in delineation of the postsurgical tumor bed based on 4D-CT

Primary and recurrent ovarian high-grade serous carcinomas display similar microRNA expression patterns relative to those of normal ovarian tissue

Clinical benefit from EGFR-TKI plus ginsenoside Rg3 in patients with advanced non-small cell lung cancer harboring EGFR active mutation

Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells

Hepatitis B virus X induces inflammation and cancer in mice liver through dysregulation of cytoskeletal remodeling and lipid metabolism

TWIST1/miR-584/TUSC2 pathway induces resistance to apoptosis in thyroid cancer cells

RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis

Relationship between tumour PTEN/Akt/COX-2 expression, inflammatory response and survival in patients with colorectal cancer

miR-135b expression downregulates Ppm1e to activate AMPK signaling and protect osteoblastic cells from dexamethasone

Ibrutinib synergizes with MDM-2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia

Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications

Apolipoprotein A1: a novel serum biomarker for predicting the prognosis of hepatocellular carcinoma after curative resection

Human PDE4D isoform composition is deregulated in primary prostate cancer and indicative for disease progression and development of distant metastases

Pseudoexons provide a mechanism for allele-specific expression of APC in familial adenomatous polyposis

miR-135a promotes gastric cancer progression and resistance to oxaliplatin

Glutathione-mediated antioxidant response and aerobic metabolism: two crucial factors involved in determining the multi-drug resistance of high-risk neuroblastoma

ESM1 mediates NGFR-induced invasion and metastasis in murine oral squamous cell carcinoma

Silencing of Profilin-1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca²⁺ signaling in T24M-based bladder cancer models

Long non-coding RNAs LOC285194, RP11-462C24.1 and Nbla12061 in serum provide a new approach for distinguishing patients with colorectal cancer from healthy controls

Different growth and metastatic phenotypes associated with a cell-intrinsic change of Met in metastatic melanoma

Randomized, placebo-controlled trial evaluating the safety of one-year administration of green tea catechins

The changing 50% inhibitory concentration (IC₅₀) of cisplatin: a pilot study on the artifacts of the MTT assay and the precise measurement of density-dependent chemoresistance in ovarian cancer

Development of a selected reaction monitoring mass spectrometry-based assay to detect asparaginyl endopeptidase activity in biological fluids

Reduced argininosuccinate synthetase expression in refractory sarcomas: Impacts on therapeutic potential and drug resistance

Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells

MiRNA-145 increases therapeutic sensibility to gemcitabine treatment of pancreatic adenocarcinoma cells

Zoledronic acid is an effective radiosensitizer in the treatment of osteosarcoma

PAK4 suppresses PDZ-RhoGEF activity to drive invadopodia maturation in melanoma cells

G-protein-coupled receptor 81 promotes a malignant phenotype in breast cancer through angiogenic factor secretion

NKp44 and NKp30 splice variant profiles in decidua and tumor tissues: a comparative viewpoint

DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelial-to-mesenchymal transition and cytoskeleton reorganization in breast cancer cells

Smoking-associated lung cancer prevention by blockade of the beta-adrenergic receptor-mediated insulin-like growth factor receptor activation

Bone marrow involvement identifies a subgroup of advanced Ewing sarcoma patients with fatal outcome irrespective of therapy in contrast to curable patients with multiple bone metastases but unaffected marrow

Concurrent paclitaxel/cisplatin chemoradiotherapy with or without consolidation chemotherapy in high-risk early-stage cervical cancer patients following radical hysterectomy: preliminary results of a phase III randomized study

Two-dimensional versus three-dimensional laparoscopy in surgical efficacy: a systematic review and meta-analysis

Hormone receptor status may impact the survival benefit of surgery in stage IV breast cancer: a population-based study

Cell-free DNA and next-generation sequencing in the service of personalized medicine for lung cancer

Combination treatment including targeted therapy for advanced hepatocellular carcinoma

Review: Traumatic brain injury and hyperglycemia, a potentially modifiable risk factor