Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer

Mieke Heyns; Olga Kovalchuk

doi:10.18632/oncotarget.5048

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Research Perspectives:

Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer

Mieke Heyns and Olga Kovalchuk _

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Oncotarget. 2015; 6:23055-23057. https://doi.org/10.18632/oncotarget.5048

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Abstract

Mieke Heyns1 and Olga Kovalchuk1

1 Department of Biological Sciences, University of Lethbridge, Lethbridge, Canada

Correspondence to:

Olga Kovalchuk, email:

Keywords: cancer, non-coding RNA, miRNA, piRNA, tRNA

Received: July 01, 2015 Accepted: July 17, 2015 Published: July 31, 2015

Abstract

Over 98% of our genes code for RNA transcripts that will never become translated into protein. Numerous non-coding RNA (ncRNA) transcripts are structurally and functionally diverse. In particular, micro RNAs (miRNAs), piwi-interacting RNAs (piRNAs), and, more recently, transfer RNAs (tRNAs) are implicated as regulators of key genes and processes that are involved in various human diseases, including cancer. Here, we summarize the recent findings and perspectives in the small RNA and cancer research.

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Research Perspectives:

Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer

Abstract