The distress thermometer as a predictor for survival in stage III lung cancer patients treated with chemotherapy

Mark de Mol; Brenda L. den Oudsten; Mieke Aarts; Joachim G.J.V. Aerts

doi:10.18632/oncotarget.14151

Oncotarget

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. The term was introduced in the inaugural Editorial, Introducing Oncotarget.

As of January 1, 2022, Oncotarget has shifted to a continuous publishing model. Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Subscribe to receive alerts once a paper has been published by Oncotarget.

Impact Journals, LLC is the publisher of Oncotarget: www.impactjournals.com.

Impact Journals is a member of the Wellcome Trust List of Compliant Publishers.

Impact Journals is a member of the Society for Scholarly Publishing.

On December 23, 2022, Oncotarget server experienced a DDoS attack. As a result, Oncotarget site was inaccessible for a few hours. Oncotarget team swiftly dealt with the situation and took it under control. This malicious action will be reported to the FBI.

Clinical Research Papers:

The distress thermometer as a predictor for survival in stage III lung cancer patients treated with chemotherapy

Mark de Mol, Brenda L. den Oudsten, Mieke Aarts and Joachim G.J.V. Aerts _

PDF | HTML | How to cite

Oncotarget. 2017; 8:36743-36749. https://doi.org/10.18632/oncotarget.14151

Metrics: PDF 1502 views | HTML 1808 views | ?

Abstract

Mark de Mol1,2, Brenda L. den Oudsten3, Mieke Aarts4 and Joachim G.J.V. Aerts1,2

1Department of Pulmonary Medicine, Erasmus University Medical Centre, Rotterdam, The Netherlands

2Department of Pulmonary Medicine, Amphia Hospital, Breda, The Netherlands

3Department of Medical and Clinical Psychology, Centre of Research on Psychological and Somatic Disorders (CoRPS), Tilburg University, Tilburg, The Netherlands

4Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, The Netherlands

Correspondence to:

Joachim G.J.V. Aerts, email: [email protected]

Keywords: distress thermometer, health related quality of life, survival, cancer, chemotherapy

Received: June 29, 2016 Accepted: November 14, 2016 Published: December 24, 2016

ABSTRACT

Background: Depression and Health Related Quality of Life have been associated with prognosis in lung cancer. As the Distress Thermometer measures emotional problems and may share similarities with aspects of Health Related Quality of Life, we aimed to retrospectively assess the prognostic value of the Distress Thermometer in lung cancer patients treated with chemotherapy.

Methods: Patients with stage III lung cancer who were treated at the day-care oncology unit with chemotherapy containing carboplatin from 2009 to 2014 and in whom a Distress Thermometer was performed at the time of the first cycle of chemotherapy were included in this study.

Results: In total, one hundred and thirteen patients were included in the analysis. In the simple Cox regression analysis, overall survival did not significantly differ according to Distress Thermometer score. No significant differences in Distress Thermometer score according to stage, histology, (intended) treatment, age, sex, and comorbidity were observed. Also in a multivariable model the Distress Thermometer was not prognostic for overall survival, whereas sex and (intended) treatment was.

Conclusions: In this study no prognostic value of the Distress Thermometer could be established in patients with stage III lung cancer treated with carboplatin. Further research is warranted to address this issue.

All site content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 License.
PII: 14151

Publication Alerts

Clinical Research Papers:

The distress thermometer as a predictor for survival in stage III lung cancer patients treated with chemotherapy

Abstract