Genomic profiling is predictive of response to cisplatin treatment but not to PI3K inhibition in bladder cancer patient-derived xenografts

Clinical and immunohistochemical characteristics of type II and type I focal cortical dysplasia

Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE^−/− mice

Stimulus-dependent dissociation between XB130 and Tks5 scaffold proteins promotes airway epithelial cell migration

The association between expression of IFIT1 in podocytes of MRL/lpr mice and the renal pathological changes it causes: An animal study

Effect of cobalt-mediated Toll-like receptor 4 activation on inflammatory responses in endothelial cells

Roles of calpain-calpastatin system (CCS) in human T cell activation

Dihydromyricetin protects against liver ischemia/reperfusion induced apoptosis via activation of FOXO3a-mediated autophagy

Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition

Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer

Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors

Dasatinib modulates sensitivity to pemetrexed in malignant pleural mesothelioma cell lines

Reduced PAK1 activity sensitizes FA/BRCA-proficient breast cancer cells to PARP inhibition

Soluble programmed death-ligand 1 (sPDL1) and neutrophil-to-lymphocyte ratio (NLR) predicts survival in advanced biliary tract cancer patients treated with palliative chemotherapy

Low dose angiostatic treatment counteracts radiotherapy-induced tumor perfusion and enhances the anti-tumor effect

SPARC overexpression in primary tumors correlates with disease recurrence and overall survival in patients with triple negative breast cancer

Immune activity and biodistribution of polypeptide K237 and folic acid conjugated amphiphilic PEG-PLGA copolymer nanoparticles radiolabeled with ^99mTc

Association of the miR-17-5p variants with susceptibility to cervical cancer in a Chinese population

The natural compound sulforaphene, as a novel anticancer reagent, targeting PI3K-AKT signaling pathway in lung cancer

MicroRNA-22 negatively regulates poly(I:C)-triggered type I interferon and inflammatory cytokine production via targeting mitochondrial antiviral signaling protein (MAVS)

Abnormal amphiregulin expression correlates with gastric cancer prognosis

Human epidermal growth factor receptor 4 (HER4) is a favorable prognostic marker of breast cancer: a systematic review and meta-analysis

Impact of HPV infection on oral squamous cell carcinoma

Up-regulation of ribosome biogenesis by MIR196A2 genetic variation promotes endometriosis development and progression

The first investigation of Wilms’ tumour atomic structure-nitrogen and carbon isotopic composition as a novel biomarker for the most individual approach in cancer disease

Human cytomegalovirus infection and colorectal cancer risk: a meta-analysis

The proprotein convertase furin is required to maintain viability of alveolar rhabdomyosarcoma cells

The ETS factor ESE3/EHF represses IL-6 preventing STAT3 activation and expansion of the prostate cancer stem-like compartment

Prognostic significance of neutrophil-lymphocyteratio/platelet-lymphocyteratioin lung cancers: a meta-analysis

IKKα regulates the stratification and differentiation of the epidermis: implications for skin cancer development

Tofacitinib induces G1 cell-cycle arrest and inhibits tumor growth in Epstein-Barr virus-associated T and natural killer cell lymphoma cells

Properdistatin inhibits angiogenesis and improves vascular function in human melanoma xenografts with low thrombospondin-1 expression

Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients

Activation of endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance of human small cell lung cancer cells by inhibiting the PI3K/AKT/mTOR signaling pathway

Clinicopathological characteristics and long-term prognosis of screening detected non-palpable breast cancer by ultrasound in hospital-based Chinese population (2001-2014)

Epigenetic silencing of miR-137 contributes to early colorectal carcinogenesis by impaired Aurora-A inhibition

Gene-environment interaction for polymorphisms in ataxia telangiectasia-mutated gene and radiation exposure in carcinogenesis: results from two literature-based meta-analyses of 27120 participants

A small deletion in SERPINC1 causes type I antithrombin deficiency by promoting endoplasmic reticulum stress

Correlation between anti-PD-L1 tumor concentrations and tumor-specific and nonspecific biomarkers in a melanoma mouse model

T-cell responses against CD19⁺ pediatric acute lymphoblastic leukemia mediated by bispecific T-cell engager (BiTE) are regulated contrarily by PD-L1 and CD80/CD86 on leukemic blasts

Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer

Prognostic significance of serum beta-2 microglobulin in patients with diffuse large B-cell lymphoma in the rituximab era

Elevation of n-3/n-6 PUFAs ratio suppresses mTORC1 and prevents colorectal carcinogenesis associated with APC mutation

CFTR is a potential marker for nasopharyngeal carcinoma prognosis and metastasis

An in vitro 3D bone metastasis model by using a human bone tissue culture and human sex-related cancer cells

Phosphorylation of PPARγ at Ser84 promotes glycolysis and cell proliferation in hepatocellular carcinoma by targeting PFKFB4

Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways

PD-L1 expression in tonsillar cancer is associated with human papillomavirus positivity and improved survival: implications for anti-PD1 clinical trials

Generation of CD20-specific TCRs for TCR gene therapy of CD20^low B-cell malignancies insusceptible to CD20-targeting antibodies

Efficacy of glycogen synthase kinase-3β targeting against osteosarcoma via activation of β-catenin

Reduced expression of FILIP1L, a novel WNT pathway inhibitor, is associated with poor survival, progression and chemoresistance in ovarian cancer

Estrogen related receptor alpha in castration-resistant prostate cancer cells promotes tumor progression in bone

Differential role of intravenous anesthetics in colorectal cancer progression: implications for clinical application

CDDO-Me reveals USP7 as a novel target in ovarian cancer cells

Meta-analysis of the correlation between selenium and incidence of hepatocellular carcinoma

Angiotensin II receptor 1 gene variants are associated with high-altitude pulmonary edema risk

TGF-β signal rewiring sustains epithelial-mesenchymal transition of circulating tumor cells in prostate cancer xenograft hosts

IL27 controls skin tumorigenesis via accumulation of ETAR-positive CD11b cells in the pre-malignant skin

Marital status is an independent prognostic factor for tracheal cancer patients: an analysis of the SEER database

Co-existence of BRAF and NRAS driver mutations in the same melanoma cells results in heterogeneity of targeted therapy resistance

Association of transcription factor 7-like 2 gene polymorphisms with breast cancer risk in northwest Chinese women

Blocking hepatic metastases of colon cancer cells using an shRNA against Rac1 delivered by activatable cell-penetrating peptide

E-cigarettes and flavorings induce inflammatory and pro-senescence responses in oral epithelial cells and periodontal fibroblasts

Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents

LncRNA profile study reveals four-lncRNA signature associated with the prognosis of patients with anaplastic gliomas

Assessment of combined expression of B7-H3 and B7-H4 as prognostic marker in esophageal cancer patients

Elevated AEG-1 expression in macrophages promotes hypopharyngeal cancer invasion through the STAT3-MMP-9 signaling pathway

PDGFR-alpha inhibits melanoma growth via CXCL10/IP-10: a multi-omics approach

Proximal and distal regulation of the HYAL1 gene cluster by the estrogen receptor α in breast cancer cells

AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer

DcR3 induces epithelial-mesenchymal transition through activation of the TGF-β3/SMAD signaling pathway in CRC

Risk of lung cancer in Parkinson’s disease

A novel 3D mesenchymal stem cell model of the multiple myeloma bone marrow niche: biologic and clinical applications

Overexpression of OCT4 is associated with gefitinib resistance in non-small cell lung cancer

Polymeric nanoparticle-docetaxel for the treatment of advanced solid tumors: phase I clinical trial and preclinical data from an orthotopic pancreatic cancer model

GWAS in the SIGNAL/PHARE clinical cohort restricts the association between the FGFR2 locus and estrogen receptor status to HER2-negative breast cancer patients

FOXM1 and STAT3 interaction confers radioresistance in glioblastoma cells

MYCL is a target of a BET bromodomain inhibitor, JQ1, on growth suppression efficacy in small cell lung cancer cells

CD133⁺CD54⁺CD44⁺ circulating tumor cells as a biomarker of treatment selection and liver metastasis in patients with colorectal cancer

Nivolumab for advanced melanoma: pretreatment prognostic factors and early outcome markers during therapy

Resistance to neoplastic transformation of ex-vivo expanded human mesenchymal stromal cells after exposure to supramaximal physical and chemical stress

c-Myc suppresses miR-451⊣YWTAZ/AKT axis via recruiting HDAC3 in acute myeloid leukemia

The feedback loop of LITAF and BCL6 is involved in regulating apoptosis in B cell non-Hodgkin’s-lymphoma

Mitochondrial Lon is over-expressed in high-grade gliomas, and mediates hypoxic adaptation: potential role of Lon as a therapeutic target in glioma

MicroRNA-7 inhibits cell proliferation, migration and invasion in human non-small cell lung cancer cells by targeting FAK through ERK/MAPK signaling pathway

Serum APE1 as a predictive marker for platinum-based chemotherapy of non-small cell lung cancer patients

FAM83D associates with high tumor recurrence after liver transplantation involving expansion of CD44+ carcinoma stem cells

miR-424 acts as a tumor radiosensitizer by targeting aprataxin in cervical cancer

Protein phosphatase Mg2+/Mn2+ dependent 1F promotes smoking-induced breast cancer by inactivating phosphorylated-p53-induced signals

Melatonin promotes goat spermatogonia stem cells (SSCs) proliferation by stimulating glial cell line-derived neurotrophic factor (GDNF) production in Sertoli cells

Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration

Peripheral blood lymphocyte subset levels differ in patients with hepatocellular carcinoma

Biopsy proportion of tumour predicts pathological tumour response and benefit from chemotherapy in resectable oesophageal carcinoma: results from the UK MRC OE02 trial

Progesterone potentiates the growth inhibitory effects of calcitriol in endometrial cancer via suppression of CYP24A1

Nuclear FOXO3 predicts adverse clinical outcome and promotes tumor angiogenesis in neuroblastoma

The relationship between total and phosphorylated STAT1 and STAT3 tumour cell expression, components of tumour microenvironment and survival in patients with invasive ductal breast cancer

Bortezomib-resistance is associated with increased levels of proteasome subunits and apoptosis-avoidance

Bcr-abl regulates Stat5 through Shp2, the interferon consensus sequence binding protein (Icsbp/Irf8), growth arrest specific 2 (Gas2) and calpain

Risk of eighteen genome-wide association study-identified genetic variants for colorectal cancer and colorectal adenoma in Han Chinese

Suppression of gain-of-function mutant p53 with metabolic inhibitors reduces tumor growth in vivo

Integrin α2β1 inhibits MST1 kinase phosphorylation and activates Yes-associated protein oncogenic signaling in hepatocellular carcinoma

Secreted protein acidic and rich in cysteine (SPARC) induces lipotoxicity in neuroblastoma by regulating transport of albumin complexed with fatty acids

SIRT1 suppresses adipogenesis by activating Wnt/β-catenin signaling in vivo and in vitro

PD-L2 negatively regulates Th1-mediated immunopathology during Fasciola hepatica infection

Efficient generation of antigen-specific CTLs by the BAFF-activated human B Lymphocytes as APCs: a novel approach for immunotherapy

The somite-secreted factor Maeg promotes zebrafish embryonic angiogenesis

MicroRNA-3196 is inhibited by H2AX phosphorylation and attenuates lung cancer cell apoptosis by downregulating PUMA

MCM10 overexpression implicates adverse prognosis in urothelial carcinoma

Prognostic value of plasma levels of HIF-1a and PGC-1a in breast cancer

Somatostatin receptor based PET/CT in patients with the suspicion of cardiac sarcoidosis: an initial comparison to cardiac MRI

Pre-clinical characterization of PKC412, a multi-kinase inhibitor, against colorectal cancer cells

Propranolol induces a favourable shift of anti-tumor immunity in a murine spontaneous model of melanoma

Reg proteins promote acinar-to-ductal metaplasia and act as novel diagnostic and prognostic markers in pancreatic ductal adenocarcinoma

Serum APN/CD13 as a novel diagnostic and prognostic biomarker of pancreatic cancer

The intrinsically kinase-inactive EPHB6 receptor predisposes cancer cells to DR5-induced apoptosis by promoting mitochondrial fragmentation

Association of vitamin D receptor Fok I polymorphism with the risk of prostate cancer: a meta-analysis

GATA4 promotes hepatoblastoma cell proliferation by altering expression of miR125b and DKK3

PDGF-CC underlies resistance to VEGF-A inhibition and combinatorial targeting of both suppresses pathological angiogenesis more efficiently

Pseudomonas aeruginosa-mannose-sensitive hemagglutinin inhibits pancreatic cancer cell proliferation and induces apoptosis via the EGFR pathway and caspase signaling

Targeting Enox1 in tumor stroma increases the efficacy of fractionated radiotherapy

Multisite phosphorylation of P-Rex1 by protein kinase C

Genetic variants of MCP-1 and CCR2 genes and IgA nephropathy risk

CD99 polymorphisms significantly influence the probability to develop Ewing sarcoma in earlier age and patient disease progression

Genetic variant in visfatin gene promoter contributes to reduced risk of hepatocellular carcinoma in a Chinese population

miR-135b-5p inhibits LPS-induced TNFα production via silencing AMPK phosphatase Ppm1e

Vasculogenic mimicry in hepatocellular carcinoma contributes to portal vein invasion

Evaluation of quantitative assays for the identification of direct signal transducer and activator of transcription 3 (STAT3) inhibitors

Methylation-associated silencing of microRNA-129-3p promotes epithelial-mesenchymal transition, invasion and metastasis of hepatocelluar cancer by targeting Aurora-A

HS-173, a novel PI3K inhibitor suppresses EMT and metastasis in pancreatic cancer

Elevation of C-reactive protein levels in patients with transfusion-related acute lung injury

CREB1 directly activates the transcription of ribonucleotide reductase small subunit M2 and promotes the aggressiveness of human colorectal cancer

Overexpression of PKM2 promotes mitochondrial fusion through attenuated p53 stability

Transposon-mediated generation of BCR-ABL1-expressing transgenic cell lines for unbiased sensitivity testing of tyrosine kinase inhibitors

Upregulation of miR-99a is associated with poor prognosis of acute myeloid leukemia and promotes myeloid leukemia cell expansion

FEN1 gene variants confer reduced risk of breast cancer in chinese women: A case-control study

Dosimetric impact of multileaf collimator leaf width according to sophisticated grade of technique in the IMRT and VMAT planning for pituitary adenoma lesion

HUR protects NONO from degradation by mir320, which is induced by p53 upon UV irradiation

HER2 mutations in Chinese patients with non-small cell lung cancer

Body mass index as a prognostic factor in patients with extranodal natural killer/T-cell lymphoma, nasal type

Diagnosis and treatment pattern among rural and urban breast cancer patients in Southwest China from 2005 to 2009

Management of advanced gastric cancer: An overview of major findings from meta-analysis