LOX-1 boosts immunity

Fatty acid synthesis and NLRP3-inflammasome

A Hrd way for MHC-II expression

Complementing regeneration

IDO-GCN2 and autophagy in inflammation

TCR signals fuel T_reg cells

IL-37 restrains autoimmune diseases

Thymic involution beyond T-cell insufficiency

OX40/OX40L axis: not a friend in autoimmunity

Protein conformation in a vaccine matters

PD-1: Dual guard for immunopathology

Regulation of T follicular helper cells by ICOS

Notch controls effector CD8+ T cell differentiation

TPL2 mediates IL-17R signaling in neuroinflammation

Uncovering HIV-1-infected cells

RUNX1 as a recombinase cofactor

Natural Th1 cells: escape from neglect

NK cell exhaustion: bad news for chronic disease?

Perifosine as a potential novel anti-telomerase therapy

In vivo hematopoietic Myc activation directs a transcriptional signature in endothelial cells within the bone marrow microenvironment

Human CD4+ T cells require exogenous cystine for glutathione and DNA synthesis

The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer

Dissecting tumor metabolic heterogeneity: Telomerase and large cell size metabolically define a sub-population of stem-like, mitochondrial-rich, cancer cells

Regulation of sensitivity of tumor cells to antitubulin drugs by Cdk1-TAZ signalling

Curcumin inhibits in vitro and in vivo chronic myelogenous leukemia cells growth: a possible role for exosomal disposal of miR-21

Knockdown of long non-coding RNA HOTAIR inhibits malignant biological behaviors of human glioma cells via modulation of miR-326

Predominant Rab-GTPase amplicons contributing to oral squamous cell carcinoma progression to metastasis

DNA repair prognostic index modelling reveals an essential role for base excision repair in influencing clinical outcomes in ER negative and triple negative breast cancers

Overexpressed tryptophanyl-tRNA synthetase, an angiostatic protein, enhances oral cancer cell invasiveness

EGFR blockade prevents glioma escape from BRAF^V600E targeted therapy

MicroRNA-153/Nrf-2/GPx1 pathway regulates radiosensitivity and stemness of glioma stem cells via reactive oxygen species

Mutational and gene fusion analyses of primary large cell and large cell neuroendocrine lung cancer

‘Cut from the same cloth’: Shared microsatellite variants among cancers link to ectodermal tissues-neural tube and crest cells

A contrasting function for miR-137 in embryonic mammogenesis and adult breast carcinogenesis

Downregulation of c-SRC kinase CSK promotes castration resistant prostate cancer and pinpoints a novel disease subclass

Combination of body mass index and oxidized low density lipoprotein receptor 1 in prognosis prediction of patients with squamous non-small cell lung cancer

Activation of PI3K/Akt/mTOR signaling in the tumor stroma drives endocrine therapy-dependent breast tumor regression

Functional relevance of a six mesenchymal gene signature in epithelial-mesenchymal transition (EMT) reversal by the triple angiokinase inhibitor, nintedanib (BIBF1120)

Analysis of the molecular features of rectal carcinoid tumors to identify new biomarkers that predict biological malignancy

Epigenetic silencing of NKD2, a major component of Wnt signaling, promotes breast cancer growth

Anti-cancer effect of snake venom toxin through down regulation of AP-1 mediated PRDX6 expression

Discovery of benzo[e]pyridoindolones as kinase inhibitors that disrupt mitosis exit while erasing AMPK-Thr172 phosphorylation on the spindle

Tivantinib (ARQ 197) affects the apoptotic and proliferative machinery downstream of c-MET: role of Mcl-1, Bcl-xl and Cyclin B1

Genome-wide mutation profiles of colorectal tumors and associated liver metastases at the exome and transcriptome levels

Endothelial-like malignant glioma cells in dynamic three dimensional culture identifies a role for VEGF and FGFR in a tumor-derived angiogenic response

Upfront molecular testing in patients with advanced gastro-esophageal cancer: Is it time yet?

PYK2 integrates growth factor and cytokine receptors signaling and potentiates breast cancer invasion via a positive feedback loop

Stathmin and phospho-stathmin protein signature is associated with survival outcomes of breast cancer patients

Osteopontin (OPN/SPP1) isoforms collectively enhance tumor cell invasion and dissemination in esophageal adenocarcinoma

Neoplastic human embryonic stem cells as a model of radiation resistance of human cancer stem cells

AS1411-conjugated gold nanospheres and their potential for breast cancer therapy

Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of patched and increase chemotherapy efficiency on melanoma cells

Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma

Regulation of split anergy in natural killer cells by inhibition of cathepsins C and H and cystatin F

Targeting Bcl-2 stability to sensitize cells harboring oncogenic ras

Anti-G-CSF treatment induces protective tumor immunity in mouse colon cancer by promoting NK cell, macrophage and T cell responses

ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of driver-negative melanoma

CRISPR/Cas9-mediated gene knockout of NANOG and NANOGP8 decreases the malignant potential of prostate cancer cells

Multifaceted role of TREX2 in the skin defense against UV-induced skin carcinogenesis

siRNA knockdown of mitochondrial thymidine kinase 2 (TK2) sensitizes human tumor cells to gemcitabine

MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis

Intact LKB1 activity is required for survival of dormant ovarian cancer spheroids

miR-620 promotes tumor radioresistance by targeting 15-hydroxyprostaglandin dehydrogenase (HPGD)

miRNA-337-3p suppresses neuroblastoma progression by repressing the transcription of matrix metalloproteinase 14

DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through Notch hyper-activation

Modulation of cerebral endothelial cell function by TGF-β in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition

Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)*

The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer

The transcriptome and miRNome profiling of glioblastoma tissues and peritumoral regions highlights molecular pathways shared by tumors and surrounding areas and reveals differences between short-term and long-term survivors

Alternative splicing of synuclein gamma in endometrial cancer: identification of a novel isoform

Regulation of migration and invasion by Toll-like receptor-9 signaling network in prostate cancer

Enhanced nucleotide excision repair capacity in lung cancer cells by preconditioning with DNA-damaging agents

EphA6 promotes angiogenesis and prostate cancer metastasis and is associated with human prostate cancer progression

Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis

Periodontal pathogens Porphyromonas gingivalis and Fusobacterium nucleatum promote tumor progression in an oral-specific chemical carcinogenesis model

Metformin inhibits cell cycle progression of B-cell chronic lymphocytic leukemia cells

Role of PAR-4 in ovarian cancer

The gain-of-function GLI1 transcription factor TGLI1 enhances expression of VEGF-C and TEM7 to promote glioblastoma angiogenesis

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer

RTVP-1 promotes mesenchymal transformation of glioma via a STAT-3/IL-6-dependent positive feedback loop

MYC amplifications in myeloma cell lines: correlation with MYC-inhibitor efficacy

Epigenetic inactivation of the candidate tumor suppressor gene ASC/TMS1 in human renal cell carcinoma and its role as a potential therapeutic target

Low DICER1 expression is associated with poor clinical outcome in adrenocortical carcinoma

The splicing modulator sudemycin induces a specific antitumor response and cooperates with ibrutinib in chronic lymphocytic leukemia

A retrospective analysis of cisplatin, pemetrexed, and bevacizumab in previously treated non-small-cell lung cancer

β-catenin stabilization enhances SS18-SSX2-driven synovial sarcomagenesis and blocks the mesenchymal to epithelial transition

F-box protein FBXO22 mediates polyubiquitination and degradation of KLF4 to promote hepatocellular carcinoma progression

Nanovehicles as a novel target strategy for hyperthermic intraperitoneal chemotherapy: a multidisciplinary study of peritoneal carcinomatosis

Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3

Next-generation sequencing of FLT3 internal tandem duplications for minimal residual disease monitoring in acute myeloid leukemia

Anti-tumor effect of inhibition of IL-6 signaling in mucoepidermoid carcinoma

Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation

Macrophage depletion reduces postsurgical tumor recurrence and metastatic growth in a spontaneous murine model of melanoma

p53 controls colorectal cancer cell invasion by inhibiting the NF-κB-mediated activation of Fascin

Co-expression of CXCL8 and HIF-1α is associated with metastasis and poor prognosis in hepatocellular carcinoma

Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasis

In vivo selection for spine-derived highly metastatic lung cancer cells is associated with increased migration, inflammation and decreased adhesion

The E3 ubiquitin ligase Cbl-b improves the prognosis of RANK positive breast cancer patients by inhibiting RANKL-induced cell migration and metastasis

Small molecule/ML327 mediated transcriptional de-repression of E-cadherin and inhibition of epithelial-to-mesenchymal transition

Molecular analysis of ovarian mucinous carcinoma reveals different cell of origins

Association of the intermediate filament nestin with cancer stage: a meta-analysis based on 223 positive/high nestin cases and 460 negative/low case-free controls

Influence of age on predictiveness of genetic risk score for prostate cancer in a Chinese hospital-based biopsy cohort

Effect of tumor size on breast cancer-specific survival stratified by joint hormone receptor status in a SEER population-based study

MicroRNA-143 is a putative predictive factor for the response to fluoropyrimidine-based chemotherapy in patients with metastatic colorectal cancer

Maintenance chemotherapy in children with ALL exerts metronomic-like thrombospondin-1 associated anti-endothelial effect

Prognostic value of HPV-mRNA in sentinel lymph nodes of cervical cancer patients with pN0-status

Loss of tumor suppressors KAI1 and p27 identifies a unique subgroup of primary melanoma patients with poor ­­prognosis