Mitochondrial transport of protoporphyrinogen IX in erythroid cells

Lipid transport and epithelial barrier integrity

RB in DNA repair

Conversion of the CD8 lineage to CD4 T cells

Exercise for the heart: signaling pathways

Similar but different: distinct roles for KRAS and BRAF oncogenes in colorectal cancer development and therapy resistance

Aberrant amino acid signaling promotes growth and metastasis of hepatocellular carcinomas through Rab1A-dependent activation of mTORC1 by Rab1A

A differentially expressed set of microRNAs in cerebro-spinal fluid (CSF) can diagnose CNS malignancies

Negative prognostic impact of regulatory T cell infiltration in surgically resected esophageal cancer post-radiochemotherapy

PRDX6 controls multiple sclerosis by suppressing inflammation and blood brain barrier disruption

Combination genetic signature stratifies lower-grade gliomas better than histological grade

Gene expression patterns through oral squamous cell carcinoma development: PD-L1 expression in primary tumor and circulating tumor cells

Mechanical phenotype of cancer cells: cell softening and loss of stiffness sensing

Virus-Clip: a fast and memory-efficient viral integration site detection tool at single-base resolution with annotation capability

Tensin4 is up-regulated by EGF-induced ERK1/2 activity and promotes cell proliferation and migration in hepatocellular carcinoma

TWIST-1 promotes cell growth, drug resistance and progenitor clonogenic capacities in myeloid leukemia and is a novel poor prognostic factor in acute myeloid leukemia

Ginkgolic acid suppresses the development of pancreatic cancer by inhibiting pathways driving lipogenesis

ANGPTL2/LILRB2 signaling promotes the propagation of lung cancer cells

Mitochondrial ribosomal protein S18-2 evokes chromosomal instability and transforms primary rat skin fibroblasts

Down regulation of Akirin-2 increases chemosensitivity in human glioblastomas more efficiently than Twist-1

MicroRNA-301a-3p promotes pancreatic cancer progression via negative regulation of SMAD4

High RAD54B expression: an independent predictor of postoperative distant recurrence in colorectal cancer patients

Pharmacological inactivation of CHK1 and WEE1 induces mitotic catastrophe in nasopharyngeal carcinoma cells

Novel HER3/MUC4 oncogenic signaling aggravates the tumorigenic phenotypes of pancreatic cancer cells

Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: an explanation for poor outcomes in obese women

By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer

A combination of YM-155, a small molecule survivin inhibitor, and IL-2 potently suppresses renal cell carcinoma in murine model

Micro-RNA-155 is induced by K-Ras oncogenic signal and promotes ROS stress in pancreatic cancer

Bcl-2^high mantle cell lymphoma cells are sensitized to acadesine with ABT-199

Ca²⁺ influx-mediated dilation of the endoplasmic reticulum and c-FLIP_L downregulation trigger CDDO-Me-induced apoptosis in breast cancer cells

Validation of an IGF-CTP scoring system for assessing hepatic reserve in egyptian patients with hepatocellular carcinoma

Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2

TMEM196 acts as a novel functional tumour suppressor inactivated by DNA methylation and is a potential prognostic biomarker in lung cancer

p53 attenuates AKT signaling by modulating membrane phospholipid composition

Spontaneously-forming spheroids as an in vitro cancer cell model for anticancer drug screening

Honokiol inhibits the growth of head and neck squamous cell carcinoma by targeting epidermal growth factor receptor

Down-regulation of α-L-fucosidase 1 expression confers inferior survival for triple-negative breast cancer patients by modulating the glycosylation status of the tumor cell surface

The peroxisome proliferator activated receptor gamma agonist pioglitazone increases functional expression of the glutamate transporter excitatory amino acid transporter 2 (EAAT2) in human glioblastoma cells

CXCR1/2 antagonism with CXCL8/Interleukin-8 analogue CXCL8_(3-72)K11R/G31P restricts lung cancer growth by inhibiting tumor cell proliferation and suppressing angiogenesis

K-Ras stabilization by estrogen via PKCδ is involved in endometrial tumorigenesis

ZD6474, a new treatment strategy for human osteosarcoma, and its potential synergistic effect with celecoxib

Aberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancer

Ataxin-3 like (ATXN3L), a member of the Josephin family of deubiquitinating enzymes, promotes breast cancer proliferation by deubiquitinating Krüppel-like factor 5 (KLF5)

Oral nano-delivery of anticancer ginsenoside 25-OCH₃-PPD, a natural inhibitor of the MDM2 oncogene: Nanoparticle preparation, characterization, in vitro and in vivo anti-prostate cancer activity, and mechanisms of action

BEX1 acts as a tumor suppressor in acute myeloid leukemia

PinX1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis by suppressing MMP-2 via NF-κB-dependent transcription

Annexin A3 is a mammary marker and a potential neoplastic breast cell therapeutic target

Identification of epidermal growth factor receptor and its inhibitory microRNA141 as novel targets of Krüppel-like factor 8 in breast cancer

NPM1 activates metabolic changes by inhibiting FBP1 while promoting the tumorigenicity of pancreatic cancer cells

Rapamycin inhibits Erk1/2-mediated neuronal apoptosis caused by cadmium

Nuclear translocation of fibroblast growth factor-2 (FGF2) is regulated by Karyopherin-β2 and Ran GTPase in human glioblastoma cells

MDM2 mediates p73 ubiquitination: a new molecular mechanism for suppression of p73 function

Analysis of the transcriptional regulation of cancer-related genes by aberrant DNA methylation of the cis-regulation sites in the promoter region during hepatocyte carcinogenesis caused by arsenic

Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling

Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies

A fully human chimeric antigen receptor with potent activity against cancer cells but reduced risk for off-tumor toxicity

Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001

Inhibition of Bcl-xL overcomes polyploidy resistance and leads to apoptotic cell death in acute myeloid leukemia cells

Distinct effects of TRAIL on the mitochondrial network in human cancer cells and normal cells: role of plasma membrane depolarization

A dominant-negative F-box deleted mutant of E3 ubiquitin ligase, β-TrCP1/FWD1, markedly reduces myeloma cell growth and survival in mice

siRNAs with decreased off-target effect facilitate the identification of essential genes in cancer cells

Effects of TGF-beta signalling inhibition with galunisertib (LY2157299) in hepatocellular carcinoma models and in ex vivo whole tumor tissue samples from patients

Intravesical administration of exogenous microRNA-145 as a therapy for mouse orthotopic human bladder cancer xenograft

Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib

Expression of miR-27a-3p is an independent predictive factor for recurrence in clear cell renal cell carcinoma

Noncanonical roles of membranous lysyl-tRNA synthetase in transducing cell-substrate signaling for invasive dissemination of colon cancer spheroids in 3D collagen I gels

Epigenetic and oncogenic regulation of SLC16A7 (MCT2) results in protein over-expression, impacting on signalling and cellular phenotypes in prostate cancer

Expression profiling of nuclear receptors in breast cancer identifies TLX as a mediator of growth and invasion in triple-negative breast cancer

ERα inhibits epithelial-mesenchymal transition by suppressing Bmi1 in breast cancer

Identification of alsterpaullone as a novel small molecule inhibitor to target group 3 medulloblastoma

Identification of novel long non-coding RNAs in triple-negative breast cancer

Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel