250 plus Papers from the Editorial Board

2017 Papers

A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy

Kelly G. Bryant, Young Chan Chae, Rogelio L. Martinez, John C. Gordon, Khaled M. Elokely, Andrew V. Kossenkov, Steven Grant, Wayne E. Childers, Magid Abou-Gharbia and Dario C. Altieri

Oncotarget. 2017 Dec 22;8(68):112184-98

Lysosome-targeting agents in cancer therapy

Guido Kroemer and Lorenzo Galluzzi

Oncotarget. 2017 Dec 22;8(68):112168-69

While reinforcing cell cycle arrest, rapamycin and Torins suppress senescence in UVA-irradiated fibroblasts

Olga V. Leontieva and Mikhail V. Blagosklonny

Oncotarget. 2017 Dec 12;8(65):109848-56

Energy metabolism in glioblastoma stem cells: PPARα a metabolic adaptor to intratumoral microenvironment

Alessia Fidoamore, Loredana Cristiano, Chiara Laezza, Renato Galzio, Elisabetta Benedetti, Benedetta Cinque, Andrea Antonosante, Michele d’Angelo, Vanessa Castelli, Maria Grazia Cifone, Rodolfo Ippoliti, Antonio Giordano and Annamaria Cimini

Oncotarget. 2017 Dec 12;8(65):108430-50

Human cytomegalovirus and Herpes Simplex type I virus can engage RNA polymerase I for transcription of immediate early genes

Ourania N. Kostopoulou, Vanessa Wilhelmi, Sina Raiss, Sharan Ananthaseshan, Mikael S. Lindström, Jiri Bartek and Cecilia Söderberg-Naucler

Oncotarget. 2017 Nov 14;8(57):96536-52

PMID: 29228551

Inhibitor of growth protein 4 interacts with Beclin 1 and represses autophagy

Valentina Sica, José Manuel Bravo-San Pedro, Guo Chen, Guillermo Mariño, Sylvie Lachkar, Valentina Izzo, Maria Chiara Maiuri, Mireia Niso-Santano and Guido Kroemer

Oncotarget. 2017 Oct 27;8(52):89527–38

PMID: 29207686

Comparative molecular analyses of left-sided colon, right-sided colon, and rectal cancers

Mohamed E. Salem, Benjamin A. Weinberg, Joanne Xiu, Wafik S. El-Deiry, Jimmy J. Hwang, Zoran Gatalica, Philip A. Philip, Anthony F. Shields, Heinz-Josef Lenz, and John L. Marshall

Oncotarget. 2017 Oct 10;8(49):86356-68

Integration of metabolomics, transcriptomics, and microRNA expression profiling reveals a miR-143-HK2-glucose network underlying zinc-deficiency-associated esophageal neoplasia

Louise Y. Fong, Ruiyan Jing, Karl J. Smalley, Cristian Taccioli, Johannes Fahrmann, Dinesh K. Barupal, Hansjuerg Alder, John L. Farber, Oliver Fiehn, and Carlo M. Croce

Oncotarget. 2017 Oct 10;8(47):81910-25

Anti-pancreatic cancer activity of ONC212 involves the unfolded protein response (UPR) and is reduced by IGF1-R and GRP78/BIP

Avital Lev, Amriti R. Lulla, Jessica Wagner, Marie D. Ralff, Joshua B. Kiehl, Yan Zhou, Cyril H. Benes, Varun V. Prabhu, Wolfgang Oster, Igor Astsaturov, David T. Dicker, and Wafik S. El-Deiry

Oncotarget. 2017 Oct 10;8(47):81776-93

Stromal cyclin D1 promotes heterotypic immune signaling and breast cancer growth

Timothy G. Pestell, Xuanmao Jiao, Mukesh Kumar, Amy R. Peck, Marco Prisco, Shengqiong Deng, Zhiping Li, Adam Ertel, Mathew C. Casimiro, Xiaoming Ju, Agnese Di Rocco, Gabriele Di Sante, Sanjay Katiyar, Alison Shupp, Michael P. Lisanti, Pooja Jain, Kongming Wu, Hallgeir Rui, Douglas C. Hooper, Zuoren Yu, Aaron R. Goldman, David W. Speicher, Lisa Laury-Kleintop, and Richard G. Pestell

Oncotarget. 2017 Oct 10;8(47):81754-75

Mesothelin as a novel biomarker and immunotherapeutic target in human glioblastoma

Zhenjiang Liu, Martin Rao, Thomas Poiret, Silvia Nava, Qingda Meng, Anna von Landenberg, Jiri Bartek Jr., Shanshan Xie, Georges Sinclair, Inti Peredo, Ernest Dodoo, and Markus Maeurer

Oncotarget. 2017 Oct 6;8(46):80208-22

Mesothelin as a novel biomarker and immunotherapeutic target in human glioblastoma

Zhenjiang Liu, Martin Rao, Thomas Poiret, Silvia Nava, Qingda Meng, Anna von Landenberg, Jiri Bartek Jr., Shanshan Xie, Georges Sinclair, Inti Peredo, Ernest Dodoo, and Markus Maeurer

Oncotarget. 2017 Oct 6;8(46):80208-22

Mitoketoscins: Novel mitochondrial inhibitors for targeting ketone metabolism in cancer stem cells (CSCs)

Bela Ozsvari, Federica Sotgia, Katie Simmons, Rachel Trowbridge, Richard Foster, and Michael P. Lisanti

Oncotarget. 2017 Oct 3;8(45):78340-50

DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt’s lymphoma

Candace J. Poole, Wenli Zheng, Atul Lodh, Aleksey Yevtodiyenko, Daniel Liefwalker, Honglin Li, Dean W. Felsher, and Jan van Riggelen

Oncotarget. 2017 Sept 29;8(44):76898-920

Targeting signaling and apoptotic pathways involved in chemotherapeutic drug-resistance of hematopoietic cells

Stephen L. Abrams, Peter P. Ruvolo, Vivian R. Ruvolo, Giovanni Ligresti, Alberto M. Martelli, Lucio Cocco, Stefano Ratti, Agostino Tafuri, Linda S. Steelman, Saverio Candido, Massimo Libra, and James A. McCubrey

Oncotarget. 2017 Sept 29;8(44):76525-57

Radiotherapy prolongs the survival of advanced non-small-cell lung cancer patients undergone to an immune-modulating treatment with dose-fractioned cisplatin and metronomic etoposide and bevacizumab (mPEBev)

Pierpaolo Pastina, Valerio Nardone, Cirino Botta, Stefania Croci, Paolo Tini, Giuseppe Battaglia, Veronica Ricci, Maria Grazia Cusi, Claudia Gandolfo, Gabriella Misso, Silvia Zappavigna, Michele Caraglia, Antonio Giordano, Donatella Aldinucci, Pierfrancesco Tassone, Pierosandro Tagliaferri, Luigi Pirtoli, and Pierpaolo Correale

Oncotarget. 2017 Sept 29;8(44):75904-13

Mitochondrial markers predict survival and progression in non-small cell lung cancer (NSCLC) patients: Use as companion diagnostics

Federica Sotgia, and Michael P. Lisanti

Oncotarget. 2017 Sept 15;8(40):68095-107

PMID: 28978099

Mitoriboscins: Mitochondrial-based therapeutics targeting cancer stem cells (CSCs), bacteria and pathogenic yeast

Bela Ozsvari, Marco Fiorillo, Gloria Bonuccelli, Anna Rita Cappello, Luca Frattaruolo, Federica Sotgia, Rachel Trowbridge, Richard Foster, and Michael P. Lisanti

Oncotarget. 2017 Sept 15;8(40):67457-72

PMID: 28978045

Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs)

Ernestina Marianna De Francesco, Gloria Bonuccelli, Marcello Maggiolini, Federica Sotgia, and Michael P. Lisanti

Oncotarget. 2017 Sept 15;8(40):67269-86

PMID: 28978032

Expression of hypothalamic neurohormones and their receptors in the human eye

Sander R. Dubovy, Maria P. Fernandez, Jose J. Echegaray, Norman L. Block, Noriyuki Unoki, Roberto Perez, Irving Vidaurre, Richard K. Lee, Mehrdad Nadji, and Andrew V. Schally

Oncotarget. 2017 Sept 15;8(40):66796-814

PMID: 28977997

Application of 3D tumoroid systems to define immune and cytotoxic therapeutic responses based on tumoroid and tissue slice culture molecular signatures

Niklas K. Finnberg, Prashanth Gokare, Avital Lev, Sergei I. Grivennikov, Alexander W. MacFarlane IV, Kerry S. Campbell, Ryan M. Winters, Karen Kaputa, Jeffrey M. Farma, Abbas El-Sayed Abbas, Luigi Grasso, Nicholas C. Nicolaides, and Wafik S. El-Deiry

Oncotarget. 2017 Sept 15;8(40):66747-57

PMID: 28977993

1,25D3 differentially suppresses bladder cancer cell migration and invasion through the induction of miR-101-3p

Yingyu Ma, Wei Luo, Brittany L. Bunch, Rachel N. Pratt, Donald L. Trump, and Candace S. Johnson

Oncotarget. 2017 Sept 1;8(36):60080-93

PMID: 28947955

Targeting hypoxic cancer stem cells (CSCs) with Doxycycline: Implications for optimizing anti-angiogenic therapy

Ernestina Marianna De Francesco, Marcello Maggiolini, Herbert B. Tanowitz, Federica Sotgia, and Michael P. Lisanti

Oncotarget. 2017 Aug 22;8(34):56126-42

PMID: 28915578

Domain analysis reveals striking functional differences between the regulatory subunits of phosphatidylinositol 3-kinase (PI3K), p85α and p85β

Yoshihiro Ito, Peter K. Vogt, and Jonathan R. Hart

Oncotarget. 2017 Aug 22;8(34):55863-76

PMID: 28915558

Pediatric and adult glioblastoma radiosensitization induced by PI3K/mTOR inhibition causes early metabolic alterations detected by nuclear magnetic resonance spectroscopy

Alice Agliano, Geetha Balarajah, Daniela M. Ciobota, Jasmin Sidhu, Paul A. Clarke, Chris Jones, Paul Workman, Martin O. Leach, and Nada M.S. Al-Saffar

Oncotarget. 2017 July 18;8(29):47969-83

PMID: 28624789

The tuberous sclerosis complex gets fatter

Prashanth Gokare, and Wafik S. El-Deiry

Oncotarget. 2017 June 27;8(26):41780-81

PMID: 28611315

BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations

Safoora Deihimi, Avital Lev, Michael Slifker, Elena Shagisultanova, Qifang Xu, Kyungsuk Jung, Namrata Vijayvergia, Eric A. Ross, Joanne Xiu, Jeffrey Swensen, Zoran Gatalica, Mark Andrake, Roland L. Dunbrack, and Wafik S. El-Deiry

Oncotarget. 2017 June 20;8(25):39945-62

PMID: 28591715

Mitochondrial matrix chaperone and c-myc inhibition causes enhanced lethality in glioblastoma

Chiaki Tsuge Ishida, Chang Shu, Marc-Eric Halatsch, Mike-Andrew Westhoff, Dario C. Altieri, Georg Karpel-Massler, and Markus David Siegelin

Oncotarget. 2017 June 6;8(23):37140-53

PMID: 28415755

A meta-analytic review of the relationship of cancer coping self-efficacy with distress and quality of life

Andrea Chirico, Fabio Lucidi, Thomas Merluzzi, Fabio Alivernini, Michelino De Laurentiis, Gerardo Botti, and Antonio Giordano

Oncotarget. 2017 May 30;8(22):36800-11

PMID: 28404938

Ultraconserved long non-coding RNA uc.63 in breast cancer

Alberto Marini, Anna Maria Lena, Emanuele Panatta, Cristina Ivan, Leng Han, Han Liang, Margherita Annicchiarico-Petruzzelli, Nicola Di Daniele, George A. Calin, Eleonora Candi, and Gerry Melino

Oncotarget. 2017 May 30;8(22):35669-80

PMID: 27447964

Circulating tumor cells (CTCs) are associated with abnormalities in peripheral blood dendritic cells in patients with inflammatory breast cancer

Michal Mego, Hui Gao, Evan N. Cohen, Simone Anfossi, Antonio Giordano, Sanda Tin, Tamer M. Fouad, Ugo De Giorgi, Mario Giuliano, Wendy A. Woodward, Ricardo H. Alvarez, Vicente Valero, Naoto T. Ueno, Gabriel N. Hortobagyi, Massimo Cristofanilli, and James M. Reuben

Oncotarget. 2017 May 30;8(22):35656-68

PMID: 27374101

Genetic landscape of extreme responders with anaplastic oligodendroglioma

Matthias Holdhoff, Gregory J. Cairncross, Thomas M. Kollmeyer, Ming Zhang, Peixin Zhang, Minesh P. Mehta, Maria Werner-Wasik, Luis Souhami, Jean-Paul Bahary, Young Kwok, Alan C. Hartford, Arnab Chakravarti, Srinivasan Yegnasubramanian, Bert Vogelstein, Nickolas Papadopoulos, Kenneth Kinzler, Robert B. Jenkins, and Chetan Bettegowda

Oncotarget. 2017 May 30;8(22):35523-31

PMID: 28388591

Therapeutic inhibition of USP7-PTEN network in chronic lymphocytic leukemia: a strategy to overcome TP53 mutated/deleted clones

Giovanna Carrà, Cristina Panuzzo, Davide Torti, Guido Parvis, Sabrina Crivellaro, Ubaldo Familiari, Marco Volante, Deborah Morena, Marcello Francesco Lingua, Mara Brancaccio, Angelo Guerrasio, Pier Paolo Pandolfi, Giuseppe Saglio, Riccardo Taulli, and Alessandro Morotti

Oncotarget. 2017 May 30;8(22):35508-22

PMID: 28418900

Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat: a phase 2 consortium/stand Up 2 cancer study

Nilofer S. Azad, Anthony el-Khoueiry, Jun Yin, Ann L. Oberg, Patrick Flynn, Douglas Adkins, Anup Sharma, Daniel J. Weisenberger, Thomas Brown, Prakriti Medvari, Peter A. Jones, Hariharan Easwaran, Ihab Kamel, Nathan Bahary, George Kim, Joel Picus, Henry C. Pitot, Charles Erlichman, Ross Donehower, Hui Shen, Peter W. Laird, Richard Piekarz, Stephen Baylin, and Nita Ahuja

Oncotarget. 2017 May 23;8(21):35326-38

PMID: 28186961

ROR1 expression as a biomarker for predicting prognosis in patients with colorectal cancer

Jian-Kang Zhou, Yu-Zhu Zheng, Xue-Sha Liu, Qiheng Gou, Rui Ma, Cheng-Lin Guo, Carlo M. Croce, Lunxu Liu, and Yong Peng

Oncotarget. 2017 May 16;8(20):32864-72

PMID: 28427197

PIGN gene expression aberration is associated with genomic instability and leukemic progression in acute myeloid leukemia with myelodysplastic features.

Emmanuel K. Teye, Abigail Sido, Ping Xin, Niklas K. Finnberg, Prashanth Gokare, Yuka I. Kawasawa, Anna C. Salzberg, Sara Shimko, Michael Bayerl, W. Christopher Ehmann, David F. Claxton, Witold B. Rybka, Joseph J. Drabick, Hong-Gang Wang, Thomas Abraham, Wafik S. El-Deiry, Robert A. Brodsky, Raymond J. Hohl, and Jeffrey J. Pu

Oncotarget. 2017 May 2;8(18):29887-905

PMID: 28187452

Suppressive role exerted by microRNA-29b-1-5p in triple negative breast cancer through SPIN1 regulation.

Rosa Drago-Ferrante, Francesca Pentimalli, Daniela Carlisi, Anna De Blasio, Christian Saliba, Shawn Baldacchino, James Degaetano, Joseph Debono, Gordon Caruana-Dingli, Godfrey Grech, Christian Scerri, Giovanni Tesoriere, Antonio Giordano, Renza Vento, and Riccardo Di Fiore

Oncotarget. 2017 April 25;8(17):28939-58

PMID: 28423652

NOS2 expression in glioma cell lines and glioma primary cell cultures: correlation with neurosphere generation and SOX-2 expression.

Paola Palumbo, Gianfranca Miconi, Benedetta Cinque, Francesca Lombardi, Cristina La Torre, Soheila Raysi Dehcordi, Renato Galzio, Annamaria Cimini, Antonio Giordano, and Maria Grazia Cifone

Oncotarget. 2017 April 11;8(15):25582-98

PMID: 28424427

Anthracyclines suppress pheochromocytoma cell characteristics, including metastasis, through inhibition of the hypoxia signaling pathway.

Ying Pang, Chunzhang Yang, Jan Schovanek, Herui Wang, Petra Bullova, Veronika Caisova, Garima Gupta, Katherine I. Wolf, Gregg L. Semenza, Zhengping Zhuang, and Karel Pacak

Oncotarget. 2017 April 4;8(14):22313-24

PMID: 28423608

MicroRNAs in melanoma development and resistance to target therapy.

Luigi Fattore, Susan Costantini, Debora Malpicci, Ciro Francesco Ruggiero, Paolo Antonio Ascierto, Carlo M. Croce, Rita Mancini, and Gennaro Ciliberto

Oncotarget. 2017 March 28;8(13):22262-78

PMID: 28118616

NADH autofluorescence, a new metabolic biomarker for cancer stem cells: Identification of Vitamin C and CAPE as natural products targeting “stemness”.

Gloria Bonuccelli, Ernestina Marianna De Francesco, Rianne de Boer, Herbert B. Tanowitz, and Michael P. Lisanti

Oncotarget. 2017 March 28;8(13):20667-78

PMID: 28223550

Mitochondrial “power” drives tamoxifen resistance: NQO1 and GCLC are new therapeutic targets in breast cancer.

Marco Fiorillo, Federica Sotgia, Diego Sisci, Anna Rita Cappello, and Michael P. Lisanti

Oncotarget. 2017 March 21;8(12):20309-27

PMID: 28411284

Analysis of acquired mutations in transgenes arising in Ba/F3 transformation assays: findings and recommendations.

Kevin Watanabe-Smith, Jamila Godil, Anupriya Agarwal, Cristina Tognon, and Brian Druker

Oncotarget. 2017 February 21;8(8):12596-606

PMID: 28208123

Identification of microRNAs implicated in the late differentiation stages of normal B cells suggests a central role for miRNA targets ZEB1 and TP53.

Giorgio Malpeli, Stefano Barbi, Simonetta Zupo, Gabriele Tosadori, Giovanni Scardoni, Anna Bertolaso, Silvia Sartoris, Stefano Ugel, Caterina Vicentini, Matteo Fassan, Annalisa Adamo, Mauro Krampera, Maria Teresa Scupoli, Carlo Maria Croce, and Aldo Scarpa

Oncotarget. 2017 February 14;8(7):11809-26

PMID: 28107180

The RNA-binding protein ESRP1 promotes human colorectal cancer progression.

Sharmila Fagoonee, Gabriele Picco, Francesca Orso, Arrigo Arrigoni, Dario L. Longo, Marco Forni, Irene Scarfò, Adele Cassenti, Roberto Piva, Paola Cassoni, Lorenzo Silengo, Emanuela Tolosano, Silvio Aime, Daniela Taverna, Pier Paolo Pandolfi, Mara Brancaccio, Enzo Medico, and Fiorella Altruda

Oncotarget. 2017 February 7;8(6):10007-24

PMID: 28052020

Targeting cancer stem cell propagation with palbociclib, a CDK4/6 inhibitor: Telomerase drives tumor cell heterogeneity.

Gloria Bonuccelli, Maria Peiris-Pages, Bela Ozsvari, Ubaldo E. Martinez-Outschoorn, Federica Sotgia, and Michael P. Lisanti

Oncotarget. 2017 February 7;8(6):9868-84

PMID: 28039467

Metformin: a metabolic modulator.

Federico Pietrocola, and Guido Kroemer

Oncotarget. 2017 February 7;8(6):9017-20

PMID: 28122334

Influence of EGFR mutational status on metastatic behavior in non squamous non small cell lung cancer.

Alessandro Russo, Tindara Franchina, Giuseppina Rosaria Rita Ricciardi, Caterina Fanizza, Antonino Scimone, Giuseppe Chiofalo, Antonio Giordano, and Vincenzo Adamo

Oncotarget. 2017 January 31;8(5):8717-25

PMID: 28060728

miR-494-3p is a novel tumor driver of lung carcinogenesis.

Alice Faversani, Stefano Amatori, Claudia Augello, Federico Colombo, Laura Porretti, Mirco Fanelli, Stefano Ferrero, Alessandro Palleschi, Pier Giuseppe Pelicci, Elena Belloni, Giulia Ercoli, Anna Degrassi, Marco Baccarin, Dario C. Altieri, Valentina Vaira, and Silvano Bosari

Oncotarget. 2017 January 31;8(5):7231-47

PMID: 27980227

Autophagy-dependent danger signaling and adaptive immunity to poorly immunogenic tumors.

Guido Kroemer, and Lorenzo Galluzzi

Oncotarget. 2017 January 24;8(4):5686-91

PMID: 27974686

Growth hormone-releasing hormone antagonist inhibits the invasiveness of human endometrial cancer cells by down-regulating twist and N-cadherin expression.

Hsien-Ming Wu, Hong-Yuan Huang, Andrew V. Schally, Angel Chao, Hung-Hsueh Chou, Peter C.K. Leung, and Hsin-Shih Wang

Oncotarget. 2017 January 17;8(3):4410-21

PMID: 28032599

2016 Papers

A novel fully human anti-NCL immunoRNase for triple-negative breast cancer therapy.

Chiara D’Avino, Dario Palmieri, Ashley Braddom, Nicola Zanesi, Cindy James, Sara Cole, Francesco Salvatore, Carlo M. Croce, and Claudia De Lorenzo

Oncotarget. 2016 December 27;7(52):87016-30

PMID: 27894092

HUR protects NONO from degradation by mir320, which is induced by p53 upon UV irradiation.

Luigi Alfano, Caterina Costa, Antonella Caporaso, Dario Antonini, Antonio Giordano, and Francesca Pentimalli

Oncotarget. 2016 November 22;7(47):78127-39

PMID: 27816966

Apoptosis inducing factor (AIF) mediates lethal redox stress induced by menadione.

Hesti Lina Wiraswati, Emilie Hangen, Ana Belén Sanz, Ngoc-Vy Lam, Camille Reinhardt, Allan Sauvat, Ariane Mogha, Alberto Ortiz, Guido Kroemer, and Nazanine Modjtahedi

Oncotarget. 2016 November 22;7(47):76496-507

PMID: 27738311

Genomic profiling is predictive of response to cisplatin treatment but not to PI3K inhibition in bladder cancer patient-derived xenografts.

Lei Wei, Sreenivasulu Chintala, Eric Ciamporcero, Swathi Ramakrishnan, May Elbanna, Jianmin Wang, Qiang Hu, Sean T. Glenn, Mitsuko Murakami, Lu Liu, Eduardo Cortes Gomez, Yuchen Sun, Jacob Conroy, Kiersten Marie Miles, Kullappan Malathi, Sudha Ramaiah, Anand Anbarasu, Anna Woloszynska-Read, Candace S. Johnson, Jeffrey Conroy, Song Liu, Carl D. Morrison, and Roberto Pili

Oncotarget. 2016 November 22;7(47):76374-89

PMID: 27823983

Discovery and clinical introduction of first-in-class imipridone ONC201.

Joshua E. Allen, C. Leah B. Kline, Varun V. Prabhu, Jessica Wagner, Jo Ishizawa, Neel Madhukar, Avital Lev, Marie Baumeister, Lanlan Zhou, Amriti Lulla, Martin Stogniew, Lee Schalop, Cyril Benes, Howard L. Kaufman, Richard S. Pottorf, B. Rao Nallaganchu, Gary L. Olson, Fahd Al-Mulla, Madeleine Duvic, Gen Sheng Wu, David T. Dicker, Mala K. Talekar, Bora Lim, Olivier Elemento, Wolfgang Oster, Joseph Bertino, Keith Flaherty, Michael L. Wang, Gautam Borthakur, Michael Andreeff, Mark Stein, and Wafik S. El-Deiry

Oncotarget. 2016 November 8;7(45):74380-92

PMID: 27602582

PML/RARa inhibits PTEN expression in hematopoietic cells by competing with PU.1 transcriptional activity.

Nélida Inés Noguera, Maria Liliana Piredda, Riccardo Taulli, Gianfranco Catalano, Giulia Angelini, Girish Gaur, Clara Nervi, Maria Teresa Voso, Andrea Lunardi, Pier Paolo Pandolfi, and Francesco Lo-Coco

Oncotarget. 2016 October 11;7(41):66386-97

PMID: 27626703

Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells.

Chuanzhao Zhang, Wanqing Iris Zhi, Haiquan Lu, Debangshu Samanta, Ivan Chen, Edward Gabrielson, and Gregg L. Semenza

Oncotarget. 2016 October 4;7(40):64527-42

PMID: 27590511

Inhibition of mTOR-kinase destabilizes MYCN and is a potential therapy for MYCN-dependent tumors.

Lynsey Vaughan, Paul A. Clarke, Karen Barker, Yvan Chanthery, Clay W. Gustafson, Elizabeth Tucker, Jane Renshaw, Florence Raynaud, Xiaodun Li, Rosemary Burke, Yann Jamin, Simon P. Robinson, Andrew Pearson, Michel Maira, William A. Weiss, Paul Workman, and Louis Chesler

Oncotarget. 2016 September 6;7(36):57525-44

PMID: 27438153

MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatment.

Pier Paolo Leoncini, Alice Bertaina, Dimitrios Papaioannou, Christian Flotho, Riccardo Masetti, Silvia Bresolin, Giuseppe Menna, Nicola Santoro, Marco Zecca, Giuseppe Basso, Giovanni Nigita, Dario Veneziano, Sara Pagotto, Katia D’Ovidio, Rossella Rota, Adrienne Dorrance, Carlo M. Croce, Charlotte Niemeyer, Franco Locatelli, and Ramiro Garzon

Oncotarget. 2016 August 23;7(34):55395-408

PMID: 27447965

Upregulation of long noncoding RNA MIAT in aggressive form of chronic lymphocytic leukemias.

Arash Sattari, Hasan Siddiqui, Farzaneh Moshiri, Apollinaire Ngankeu, Tatsuya Nakamura, Thomas J. Kipps, and Carlo M. Croce

Oncotarget. 2016 August 23;7(34):54174-82

PMID: 27527866

Agonistic analogs of growth hormone releasing hormone (GHRH) promote wound healing by stimulating the proliferation and survival of human dermal fibroblasts through ERK and AKT pathways.

Tengjiao Cui, Joaquin J. Jimenez, Norman L. Block, Evangelos V. Badiavas, Luis Rodriguez-Menocal, Ailin Vila Granda, Renzhi Cai, Wei Sha, Marta Zarandi, Roberto Perez, and Andrew V. Schally

Oncotarget. 2016 August 16;7(33):52661-72

PMID: 27494841

β1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation.

Aejaz Sayeed, Huimin Lu, Qin Liu, David Deming II, Alexander Duffy, Peter McCue, Adam P. Dicker, Roger J. Davis, Dmitry Gabrilovich, Ulrich Rodeck, Dario C. Altieri, and Lucia R. Languino

Oncotarget. 2016 August 16;7(33):52618-30

PMID: 27438371

Anti-proliferative and pro-apoptotic effects of GHRH antagonists in prostate cancer.

Laura Muñoz-Moreno, M. Isabel Arenas, María J. Carmena, Andrew V. Schally, Manuel Sánchez-Chapado, Juan C. Prieto, and Ana M. Bajo

Oncotarget. 2016 August 9;7(32):52195-206

PMID: 27448980

Pharmacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers associated with the complete pathological response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2 positive breast cancer.

Gianmaria Miolo, Elena Muraro, Donatella Caruso, Diana Crivellari, Anthony Ash, Simona Scalone, Davide Lombardi, Flavio Rizzolio, Antonio Giordano, and Giuseppe Corona

Oncotarget. 2016 June 28;7(26):39809-22.

PMID: 27223427

The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation.

Christophe Le Clorennec, Yassamine Lazrek, Olivier Dubreuil, Christel Larbouret, Marie-Alix Poul, Philippe Mondon, Gerry Melino, André Pèlegrin, and Thierry Chardès

Oncotarget. 2016 June 14;7(24):37013-29.

PMID: 27203743

Repurposing atovaquone: Targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells.

Marco Fiorillo, Rebecca Lamb, Herbert B. Tanowitz, Luciano Mutti, Marija Krstic-Demonacos, Anna Rita Cappello, Ubaldo E. Martinez-Outschoorn, Federica Sotgia, and Michael P. Lisanti

Oncotarget. 2016 June 7;7(23):34084-99.

PMID: 27136895

Inhibitors of Rho kinase (ROCK) signaling revert the malignant phenotype of breast cancer cells in 3D context.

Masahiro Matsubara, and Mina J. Bissell

Oncotarget. 2016 May 31;7(22):31602-22.

PMID: 27203208

Sexual dimorphism of liver metastasis by murine pancreatic neuroendocrine tumors is affected by expression of complement C5.

Tanupriya Contractor, Shinta Kobayashi, Edaise da Silva, Richard Clausen, Chang Chan, Evan Vosburgh, Laura H. Tang, Arnold J. Levine, and Chris R. Harris

Oncotarget. 2016 May 24;7(21):30585-96.

PMID: 27105526

Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes.

Lia R. Edmunds, P. Anthony Otero, Lokendra Sharma, Sonia D’Souza, James M. Dolezal, Sherin David, Jie Lu, Lauren Lamm, Mahesh Basantani, Pili Zhang, Ian J. Sipula, Lucy Li, Xuemei Zeng, Ying Ding, Fei Ding, Megan E. Beck, Jerry Vockley, Satdarshan P. S. Monga, Erin E. Kershaw, Robert M. O’Doherty, Lisa E. Kratz, Nathan A. Yates, Eric P. Goetzman, Donald Scott, Andrew W. Duncan, and Edward V. Prochownik

Oncotarget. 2016 May 24;7(21):30379-95.

PMID: 27105497

A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells.

Eugenio Gaudio, Francesco Paduano, Apollinaire Ngankeu, Francesco Ortuso, Francesca Lovat, Sandra Pinton, Sabrina D’Agostino, Nicola Zanesi, Rami I. Aqeilan, Pietro Campiglia, Ettore Novellino, Stefano Alcaro, Carlo M. Croce, and Francesco Trapasso

Oncotarget. 2016 May 24;7(21):29927-36.

PMID: 27166255

Metabolic pathways regulated by TAp73 in response to oxidative stress.

Massimiliano Agostini, Margherita Annicchiarico-Petruzzelli, Gerry Melino, and Alessandro Rufini

Oncotarget. 2016 May 24;7(21):29881-900.

PMID: 27119504

Metabolic vulnerabilities of MYC-induced cancer.

Arvin M. Gouw, Georgia G. Toal, and Dean W. Felsher

Oncotarget. 2016 May 24;7(21):29879-80.

PMID: 26863454

Amino acid deprivation promotes intestinal homeostasis through autophagy.

Lorenzo Galluzzi, and Guido Kroemer

Oncotarget. 2016 May 24;7(21):29877-78.

PMID: 27105494

Chromatin dysregulation by mutant p53.

Neil T. Pfister, and Carol Prives

Oncotarget. 2016 May 24;7(21):29875-76.

PMID: 27127877

Setdb1, a novel interactor of ΔNp63, is involved in breast tumorigenesis.

Carla Regina, Mirco Compagnone, Angelo Peschiaroli, AnnaMaria Lena, Margherita Annicchiarico-Petruzzelli, Maria Cristina Piro, Gerry Melino, and Eleonora Candi

Oncotarget. 2016 May 17;7(20):28836-48.

PMID: 26840455

Can the microRNA expression profile help to identify novel targets for zoledronic acid in breast cancer?

Daniele Fanale, Valeria Amodeo, Viviana Bazan, Lavinia Insalaco, Lorena Incorvaia, Nadia Barraco, Marta Castiglia, Sergio Rizzo, Daniele Santini, Antonio Giordano, Sergio Castorina, and Antonio Russo

Oncotarget. 2016 May 17;7(20):29321-32.

PMID: 27081088

BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia.

Yulin Li, Anja Deutzmann, Peter S. Choi, Alice C. Fan, and Dean W. Felsher

Oncotarget. 2016 May 10;7(19):26926-34.

PMID: 27095570

A new immunohistochemistry prognostic score (IPS) for recurrence and survival in resected pancreatic neuroendocrine tumors (PanNET).

Antonio Viúdez, Filipe L.F. Carvalho, Zahra Maleki, Marianna Zahurak, Daniel Laheru, Alejandro Stark, Nilofer Z. Azad, Christopher L. Wolfgang, Stephen Baylin, James G. Herman, and Ana De Jesus-Acosta

Oncotarget. 2016 May 3;7(18):24950-61.

PMID: 26894863

Alterations of tumor microenvironment by carbon monoxide impedes lung cancer growth.

Zsuzsanna Nemeth, Eva Csizmadia, Lisa Vikstrom, Mailin Li, Kavita Bisht, Alborz Feizi, Sherrie Otterbein, Brian Zuckerbraun, Daniel B. Costa, Pier Paolo Pandolfi, Janos Fillinger, Balazs Döme, Leo E. Otterbein, and Barbara Wegiel

Oncotarget. 2016 April 26;7(17):23919-32.

PMID: 26993595

MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors.

Matteo Rossi, David Colecchia, Gennaro Ilardi, Mario Acunzo, Giovanni Nigita, Federica Sasdelli, Angela Celetti, Angela Strambi, Stefania Staibano, Carlo Maria Croce, and Mario Chiariello

Oncotarget. 2016 April 12;7(15):20981-98.

PMID: 26988910

Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors.

Joanna Kopecka, Stefania Porto, Sara Lusa, Elena Gazzano, Giuseppina Salzano, Martha Leonor Pinzòn-Daza, Antonio Giordano, Vincenzo Desiderio, Dario Ghigo, Giuseppe De Rosa, Michele Caraglia, and Chiara Riganti

Oncotarget. 2016 April 12;7(15):20753-72.

PMID: 26980746

miR-340 predicts glioblastoma survival and modulates key cancer hallmarks through down-regulation of NRAS.

Danilo Fiore, Elvira Donnarumma, Giuseppina Roscigno, Margherita Iaboni, Valentina Russo, Alessandra Affinito, Assunta Adamo, Fabio De Martino, Cristina Quintavalle, Giulia Romano, Adelaide Greco, Ylermi Soini, Arturo Brunetti, Carlo M. Croce, and Gerolama Condorelli

Oncotarget. 2016 April 12;7(15):19531-47.

PMID: 26799668

Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells.

Dario Palmieri, Mario Scarpa, Anna Tessari, Rexhep Uka, Foued Amari, Cindy Lee, Timothy Richmond, Claudia Foray, Tyler Sheetz, Ashley Braddom, Christin E. Burd, Jeffrey D. Parvin, Thomas Ludwig, Carlo M. Croce, and Vincenzo Coppola

Oncotarget. 2016 April 5;7(14):18371-83.

PMID: 26943034

FoxO1 regulates allergic asthmatic inflammation through regulating polarization of the macrophage inflammatory phenotype.

Sangwoon Chung, Tae Jin Lee, Brenda F. Reader, Ji Young Kim, Yong Gyu Lee, Gye Young Park, Manjula Karpurapu, Megan N. Ballinger, Feng Qian, Luiza Rusu, Hae Young Chung, Terry G. Unterman, Carlo M. Croce, and John W. Christman

Oncotarget. 2016 April 5;7(14):17532-46.

PMID: 27007158

microRNA-206 impairs c-Myc-driven cancer in a synthetic lethal manner by directly inhibiting MAP3K13.

Han Han, Yuxing Chen, Li Cheng, Edward V. Prochownik, and Youjun Li

Oncotarget. 2016 March 29;7(13):16409-19.

PMID: 26918941

p73 promotes glioblastoma cell invasion by directly activating POSTN (periostin) expression.

Vivien Landré, Alexey Antonov, Richard Knight, and Gerry Melino

Oncotarget. 2016 March 15;7(11):111785-802.

PMID: 26930720

MicroRNA dysregulation and esophageal cancer development depend on the extent of zinc dietary deficiency.

Louise Y. Fong, Cristian Taccioli, Ruiyan Jing, Karl J. Smalley, Hansjuerg Alder, Yubao Jiang, Paolo Fadda, John L. Farber, and Carlo M. Croce

Oncotarget. 2016 March 8;7(10):10723-38.

PMID: 26918602

Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma.

Ke Hu, Savalan Babapoor-Farrokhran, Murilo Rodrigues, Monika Deshpande, Brooks Puchner, Fabiana Kashiwabuchi, Syed Junaid Hassan, Laura Asnaghi, James T. Handa, Shannath Merbs, Charles G. Eberhart, Gregg L. Semenza, Silvia Montaner, and Akrit Sodhi

Oncotarget. 2016 Feb 16;7(7):7816-28.

PMID: 26761211

MTHFD2- a new twist?

Philip M. Tedeschi, Kathleen W. Scotto, John Kerrigan, and Joseph R. Bertino

Oncotarget. 2016 Feb 16;7(7):7368-69.

PMID: 26848977

IRS2 silencing increases apoptosis and potentiates the effects of ruxolitinib in JAK2V617F-positive myeloproliferative neoplasms.

Paula de Melo Campos, João A. Machado-Neto, Christopher A. Eide, Samantha L. Savage, Renata Scopim-Ribeiro, Adriana da Silva Souza Duarte, Patricia Favaro, Irene Lorand-Metze, Fernando F. Costa, Cristina E. Tognon, Brian J. Druker, Sara T. Olalla Saad, and Fabiola Traina

Oncotarget. 2016 Feb 9;7(6):6948-59.

PMID: 26755644

PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia.

Weibo Luo, Ivan Chen, Yan Chen, Duah Alkam, Yingfei Wang, and Gregg L. Semenza

Oncotarget. 2016 Feb 9;7(6):6379-97.

PMID: 26837221

CEST theranostics: label-free MR imaging of anticancer drugs.

Yuguo Li, Hanwei Chen, Jiadi Xu, Nirbhay N. Yadav, Kannie W. Y. Chan, Liangping Luo, Michael T. McMahon, Bert Vogelstein, Peter C.M. van Zijl, Shibin Zhou, and Guanshu Liu

Oncotarget. 2016 Feb 9;7(6):6369-78.

PMID: 26837220

Liposome armed with herpes virus-derived gH625 peptide to overcome doxorubicin resistance in lung adenocarcinoma cell lines.

Emiliana Perillo, Stefania Porto, Annarita Falanga, Silvia Zappavigna, Paola Stiuso, Virginia Tirino, Vincenzo Desiderio, Gianpaolo Papaccio, Massimiliano Galdiero, Antonio Giordano, Stefania Galdiero, and Michele Caraglia

Oncotarget. 2016 Jan 26;7(4):4077-92.

PMID: 26554306

A multiplexed marker-based algorithm for diagnosis of carcinoma of unknown primary using circulating tumor cells.

Elizabeth M. Matthew, Lanlan Zhou, Zhaohai Yang, David T. Dicker, Sheldon L. Holder, Bora Lim, Ramdane Harouaka, Si-Yang Zheng, Joseph J. Drabick, Nicholas E. Lamparella, Cristina I. Truica, and Wafik S. El-Deiry

Oncotarget. 2016 Jan 26;7(4):3662-76.

PMID: 26695546

Blocking the survival of the nastiest by HSP90 inhibition.

Paul Workman, Paul A. Clarke, and Bissan Al-Lazikani

Oncotarget. 2016 Jan 26;7(4):3658-61.

PMID: 26820296

Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition.

Mohamed Jemaà, Gwenola Manic, Gwendaline Lledo, Delphine Lissa, Christelle Reynes, Nathalie Morin, Frédéric Chibon, Antonella Sistigu, Maria Castedo, Ilio Vitale, Guido Kroemer, and Ariane Abrieu

Oncotarget. 2016 Jan 5;7(1):885-901.

PMID: 26637805

miR-302b enhances breast cancer cell sensitivity to cisplatin by regulating E2F1 and the cellular DNA damage response.

Alessandra Cataldo, Douglas G. Cheung, Andrea Balsari, Elda Tagliabue, Vincenzo Coppola, Marilena V. Iorio, Dario Palmieri, and Carlo M. Croce

Oncotarget. 2016 Jan 5;7(1):786-97.

PMID: 26623722

Common variations in TERT-CLPTM1L locus are reproducibly associated with the risk of nasopharyngeal carcinoma in Chinese populations.

Yang Zhang, Xiaoai Zhang, Hongxing Zhang, Yun Zhai, Zhifu Wang, Peiyao Li, Lixia Yu, Xia Xia, Ying Zhang, Yixin Zeng, Fuchu He, and Gangqiao Zhou

Oncotarget. 2016 Jan 5;7(1):759-70.

PMID: 26621837

MiR-221 promotes stemness of breast cancer cells by targeting DNMT3b.

Giuseppina Roscigno, Cristina Quintavalle, Elvira Donnarumma, Ilaria Puoti, Angel Diaz-Lagares, Margherita Iaboni, Danilo Fiore, Valentina Russo, Matilde Todaro, Giulia Romano, Renato Thomas, Giuseppina Cortino, Miriam Gaggianesi, Manel Esteller, Carlo M. Croce, and Gerolama Condorelli

Oncotarget. 2016 Jan 5;7(1):580-92.

PMID: 26556862

Virus-encoded microRNA contributes to the molecular profile of EBV-positive Burkitt lymphomas.

Pier Paolo Piccaluga, Mohsen Navari, Giulia De Falco, Maria Raffaella Ambrosio, Stefano Lazzi, Fabio Fuligni, Cristiana Bellan, Maura Rossi, Maria Rosaria Sapienza, Maria Antonella Laginestra, Maryam Etebari, Emily A. Rogena, Lynnette Tumwine, Claudio Tripodo, Davide Gibellini, Jessica Consiglio, Carlo M. Croce, Stefano A. Pileri, and Lorenzo Leoncini

Oncotarget. 2016 Jan 5;7(1):224-40.

PMID: 26325594

Endosome and INPP4B.

Chen Li Chew, Ming Chen, Pier Paolo Pandolfi

Oncotarget. 2016 Jan 5;7(1):5-6.

PMID: 26700619

2015 Papers

Targeting CXCR1 on breast cancer stem cells: signaling pathways and clinical application modelling.

Laura Brandolini, Loredana Cristiano, Alessia Fidoamore, Maria De Pizzol, Erica Di Giacomo, Tiziana Marilena Florio, Giuseppina Confalone, Angelo Galante, Benedetta Cinque, Elisabetta Benedetti, Pier Adelchi Ruffini, Maria Grazia Cifone, Antonio Giordano, Marcello Alecci, Marcello Allegretti, and Annamaria Cimini

Oncotarget. 2015 Dec 22;6(41):43375-94.

PMID: 26517518

Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAFV600E patient-derived papillary thyroid carcinoma preclinical model.

Mark Duquette, Peter M. Sadow, Amjad Husain, Jennifer N. Sims, Zeus A. Antonello, Andrew H. Fischer, Chen Song, Elena Castellanos-Rizaldos, G. Mike Makrigiorgos, Junichi Kurebayashi, Vania Nose, Paul Van Hummelen, Roderick T. Bronson, Michelle Vinco, Thomas J. Giordano, Dora Dias-Santagata, Pier Paolo Pandolfi, and Carmelo Nucera

Oncotarget. 2015 Dec 15;6(40):42445-67.

PMID: 26636651

Nucleolin antagonist triggers autophagic cell death in human glioblastoma primary cells and decreased in vivo tumor growth in orthotopic brain tumor model.

Elisabetta Benedetti, Andrea Antonosante, Michele d’Angelo, Loredana Cristiano, Renato Galzio, Damien Destouches, Tiziana Marilena Florio, Anne Chloé Dhez, Carlo Astarita, Benedetta Cinque, Alessia Fidoamore, Floriana Rosati, Maria Grazia Cifone, Rodolfo Ippoliti, Antonio Giordano, José Courty, and Annamaria Cimini.

Oncotarget. 2015 Dec 8;6(39):42091-104.

PMID: 26540346

Morphometric analysis of immunoselection against hyperploid cancer cells.

Norma Bloy, Allan Sauvat, Kariman Chaba, Aitziber Buqué, Juliette Humeau, José Manuel Bravo-San Pedro, Jack Bui, Oliver Kepp, Guido Kroemer, and Laura Senovilla.

Oncotarget. 2015 Dec 1;6(38):41204-15.

PMID: 26517677

Defective autophagy gets to the brain.

Lorenzo Galluzzi, and Guido Kroemer.

Oncotarget. 2015 Nov 24;6(37):39396-7.

PMID: 26575951

Inflammasome effects in GvHD.

Brent H. Koehn, Robert Zeiser, and Bruce R. Blazar.

Oncotarget. 2015 Nov 17;6(36):38444-5.

PMID: 26564963

Q-ing tumor glutaminase for therapy.

Zachary E. Stine, and Chi V. Dang.

Oncotarget. 2015 Nov 17;6(36):38440-1.

PMID: 26564960

p73 regulates basal and starvation-induced liver metabolism in vivo.

Zhaoyue He, Massimiliano Agostini, He Liu, Gerry Melino, and Hans-Uwe Simon.

Oncotarget. 2015 Oct 20;6(32):33178-90.

PMID: 26375672

An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer.

Marco Agostini, Klaus-Peter Janssen, Il-Jin Kim, Edoardo D’Angelo, Silvia Pizzini, Andrea Zangrando, Carlo Zanon, Chiara Pastrello, Isacco Maretto, Maura Digito, Chiara Bedin, Igor Jurisica, Flavio Rizzolio, Antonio Giordano, Stefania Bortoluzzi, Donato Nitti, and Salvatore Pucciarelli.

Oncotarget. 2015 Oct 20;6(32):32561-74.

PMID: 26359356

Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids.

Huabo Wang, Peter Teriete, Angela Hu, Dhanya Raveendra-Panickar, Kelsey Pendelton, John S. Lazo, Julie Eiseman, Toril Holien, Kristine Misund, Ganna Oliynyk, Marie Arsenian-Henriksson, Nicholas D. P. Cosford, Anders Sundan, and Edward V. Prochownik.

Oncotarget. 2015 Oct 20;6(32):32380-95.

PMID: 26474287

Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells.

Joanna Kopecka, Stefania Porto, Sara Lusa, Elena Gazzano, Giuseppina Salzano, Antonio Giordano, Vincenzo Desiderio, Dario Ghigo, Michele Caraglia, Giuseppe De Rosa, and Chiara Riganti.

Oncotarget. 2015 Oct 13;6(31):31461-78.

PMID: 26372812

High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant.

Gillian Farnie, Federica Sotgia, and Michael P. Lisanti.

Oncotarget. 2015 Oct 13;6(31):30472-86.

PMID: 26421710

Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling.

Rebecca Lamb, Gloria Bonuccelli, Béla Ozsvári, Maria Peiris-Pagès, Marco Fiorillo, Duncan L. Smith, Generoso Bevilacqua, Chiara Maria Mazzanti, Liam A. McDonnell, Antonio Giuseppe Naccarato, Maybo Chiu, Luke Wynne, Ubaldo E. Martinez-Outschoorn, Federica Sotgia, and Michael P. Lisanti.

Oncotarget. 2015 Oct 13;6(31):30453-71.

PMID: 26421711

Inhibition of miR-21 restores RANKL/OPG ratio in multiple myeloma-derived bone marrow stromal cells and impairs the resorbing activity of mature osteoclasts.

Maria Rita Pitari, Marco Rossi, Nicola Amodio, Cirino Botta, Eugenio Morelli, Cinzia Federico, Annamaria Gullà, Daniele Caracciolo, Maria Teresa Di Martino, Mariamena Arbitrio, Antonio Giordano, Pierosandro Tagliaferri, Pierfrancesco Tassone.

Oncotarget. 2015 Sep 29;6(29):27343-58.

PMID: 26160841

A decade of EGFR inhibition in EGFR-mutated non small cell lung cancer (NSCLC): Old successes and future perspectives

Alessandro Russo, Tindara Franchina, Giuseppina Rosaria Rita Ricciardi, Antonio Picone, Giuseppa Ferraro, Mariangela Zanghì, Giuseppe Toscano, Antonio Giordano, and Vincenzo Adamo.

Oncotarget. 2015 Sep 29;6(29):26814-25.

PMID: 26308162

The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization

Heng Zhou, Sabrina Forveille, Allan Sauvat, Valentina Sica, Valentina Izzo, Sylvère Durand, Kevin Müller, Peng Liu, Laurence Zitvogel, Øystein Rekdal, Oliver Kepp, and Guido Kroemer.

Oncotarget. 2015 Sep 29;6(29):26599-614.

PMID: 26378049

Triple negative breast cancer: looking for the missing link between biology and treatments

Giuseppe Palma, Giuseppe Frasci, Andrea Chirico, Emanuela Esposito, Claudio Siani, Carmela Saturnino, Claudio Arra, Gennaro Ciliberto, Antonio Giordano, and Massimiliano D’Aiuto.

Oncotarget. 2015 Sep 29;6(29):26560-74.

PMID: 26387133

KMT Set7/9 affects genotoxic stress response via the Mdm2 axis

Larissa Lezina, Vasilisa Aksenova, Olga Fedorova, Daria Malikova, Oleg Shuvalov, Alexey V. Antonov, Dmitri Tentler, Alexander V. Garabadgiu, Gerry Melino, and Nikolai A. Barlev.

Oncotarget. 2015 Sep 22;6(28):25843-55.

PMID: 26317544

Estrogen related receptor α (ERRα) a promising target for the therapy of adrenocortical carcinoma (ACC)

Ivan Casaburi, Paola Avena, Arianna De Luca, Adele Chimento, Rosa Sirianni, Rocco Malivindi, Vittoria Rago, Marco Fiorillo, Francesco Domanico, Carmela Campana, Anna Rita Cappello, Federica Sotgia, Michael P. Lisanti, and Vincenzo Pezzi.

Oncotarget. 2015 Sep 22;6(28):25135-48.

PMID: 26312764

New findings on primary and acquired resistance to anti-EGFR therapy in metastatic colorectal cancer: do all roads lead to RAS?

Giuseppe Bronte, Nicola Silvestris, Marta Castiglia, Antonio Galvano, Francesco Passiglia, Giovanni Sortino, Giuseppe Cicero, Christian Rolfo, Marc Peeters, Viviana Bazan, Daniele Fanale, Antonio Giordano, and Antonio Russo.

Oncotarget. 2015 Sep 22;6(28):24780-96.

PMID: 26318427

The 26S proteasome is a multifaceted target for anti-cancer therapies.

Tatyana A. Grigoreva, Vyacheslav G. Tribulovich, Alexander V. Garabadzhiu, Gerry Melino, and Nickolai A. Barlev.

Oncotarget. 2015 Sep 22;6(28):24733-49.

PMID: 26295307

Quaking and miR-155 interactions in inflammation and leukemogenesis.

Esmerina Tili, Marcela Chiabai, Dario Palmieri, Melissa Brown, Ri Cui, Cecilia Fernandes, Tim Richmond, Taewan Kim, Tyler Sheetz, Hui-Lung Sun, Alessandro Lagana, Dario Veneziano, Stefano Volinia, Laura Rassenti, Thomas Kipps, Hamdy Awad, Jean-Jacques Michaille, and Carlo M. Croce.

Oncotarget. 2015 Sep 22;6(28):24599-610.

PMID: 26337206

Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasis.

Michael W. Pickup, Laura D. Hover, Yan Guo, Agnieszka E. Gorska, Anna Chytil, Sergey V. Novitskiy, Harold L. Moses and Philip Owens.

Oncotarget. 2015 Sep 8;6(26):22890-904

PMID: 26274893

Dissecting tumor metabolic heterogeneity: Telomerase and large cell size metabolically define a sub-population of stem-like, mitochondrial-rich, cancer cells.

Rebecca Lamb, Bela Ozsvari, Gloria Bonuccelli, Duncan L. Smith, Richard G. Pestell, Ubaldo E. Martinez-Outschoorn, Robert B. Clarke, Federica Sotgia, and Michael P. Lisanti.

Oncotarget. 2015 Sep 8;6(26):21892-905.

PMID: 26323205

MicroRNA-224 is implicated in lung cancer pathogenesis through targeting caspase-3 and caspase-7.

Ri Cui, Taewan Kim, Matteo Fassan, Wei Meng, Hui-Lung Sun, Young-Jun Jeon, Caterina Vicentini, Esmerina Tili, Yong Peng, Aldo Scarpa, Guang Liang, Yong Kui Zhang, Arnab Chakravarti, and Carlo M. Croce.

Oncotarget. 2015 Sep 8;6(26):21802-15.

PMID: 26307684

Negative prognostic impact of regulatory T cell infiltration in surgically resected esophageal cancer post-radiochemotherapy.

Erika Vacchelli, Michaela Semeraro, David P. Enot, Kariman Chaba, Vichnou Poirier Colame, Peggy Dartigues, Aurelie Perier, Irene Villa, Sylvie Rusakiewicz, Caroline Gronnier, Diane Goéré, Christophe Mariette, Laurence Zitvogel, and Guido Kroemer.

Oncotarget. 2015 Aug 28;6(25):20840-50.

PMID: 26369701

A differentially expressed set of micrornas in cerebro-spinal fluid (CSF) can diagnose CNS malignancies.

Alessandra Drusco, Arianna Bottoni, Alessandro Laganà, Mario Acunzo, Matteo Fassan, Luciano Cascione, Anna Antenucci, Prasanthi Kumchala, Caterina Vicentini, Marina P. Gardiman, Hansjuerg Alder, Mariantonia A. Carosi, Mario Ammirati, Stefano Gherardi, Marilena Luscrì, Carmine Carapella, Nicola Zanesi, Carlo M. Croce.

Oncotarget. 2015 Aug 28;6(25):20829-39

PMID: 26246487

miR-181b as a therapeutic agent for chronic lymphocytic leukemia in the Eµ-TCL1 mouse model.

Antonella Bresin, Elisa Callegari, Lucilla D’Abundo, Caterina Cattani, Cristian Bassi, Barbara Zagatti, M. Grazia Narducci, Elisabetta Caprini, Yuri Pekarsky, Carlo M. Croce, Silvia Sabbioni, Giandomenico Russo and Massimo Negrini.

Oncotarget. 2015 Aug 28;6(25):19807-18

PMID: 26090867

Small molecule inhibitor screen identifies synergistic activity of the bromodomain inhibitor CPI203 and bortezomib in drug resistant myeloma.

Matthew B. Siegel, Selina Qiuying Liu, Monika A. Davare, Stephen E. Spurgeon, Marc M. Loriaux, Brian J. Druker, Emma C. Scott, and Jeffrey W. Tyner.

Oncotarget. 2015 Aug 7;6(22):18921-32

PMID: 26254279

MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression.

Taewan Kim, Ri Cui, Young-Jun Jeon, Paolo Fadda, Hansjuerg Alder, Carlo M. Croce.

Oncotarget. 2015 Aug 7;6(22):18780-9

PMID: 26003165

RB1 dual role in proliferation and apoptosis: cell fate control and implications for cancer therapy.

Paola Indovina, Francesca Pentimalli, Nadia Casini, Immacolata Vocca, Antonio Giordano.

Oncotarget. 2015 Jul 20;6(20):17873-90. Review.

PMID: 26160835

Anti-tumoral effect of desmethylclomipramine in lung cancer stem cells.

Lucilla Bongiorno-Borbone, Arianna Giacobbe, Mirco Compagnone, Adriana Eramo, Ruggero De Maria, Angelo Peschiaroli, and Gerry Melino.

Oncotarget. 2015 Jul 10;6(19):16926-38.

PMID: 26219257

Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion.

Huabo Wang, Lokendra Sharma, Jie Lu, Paul Finch, Steven Fletcher, and Edward V. Prochownik.

Oncotarget. 2015 Jun 30;6(18):15857-70.

PMID: 26036281

Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells.

Arianna De Luca, Marco Fiorillo, Maria Peiris-Pagès, Bela Ozsvari, Duncan L. Smith, Rosa Sanchez-Alvarez, Ubaldo E. Martinez-Outschoorn, Anna Rita Cappello, Vincenzo Pezzi, Michael P. Lisanti, and Federica Sotgia

Oncotarget. 2015 Jun 20;6(17):14777-95.

PMID: 26087310

RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model.

Tae Jin Lee, Farzin Haque, Dan Shu, Ji Young Yoo, Hui Li, Robert A. Yokel, Craig Horbinski, Tae Hyong Kim, Sung-Hak Kim, Chang-Hyuk Kwon, Ichiro Nakano, Balveen Kaur, Peixuan Guo, Carlo M. Croce.

Oncotarget. 2015 Jun 20;6(17):14766-76.

PMID: 25885522

Axl receptor tyrosine kinase is up-regulated in metformin resistant prostate cancer cells.

Nitu Bansal, Prasun J. Mishra, Mark Stein, Robert S. DiPaola and Joseph R. Bertino.

Oncotarget. 2015 Jun 20;6(17):15321-31.

PMID: 26036314

Monocytes and macrophages, implications for breast cancer migration and stem cell-like activity and treatment.

Rebecca Ward, Andrew H. Sims, Alexander Lee, Christina Lo, Luke Wynne, Humza Yusuf, Hannah Gregson, Michael P. Lisanti, Federica Sotgia, Göran Landberg, and Rebecca Lamb.

Oncotarget. 2015 Jun 10;6(16):14687-99.

PMID: 26008983

Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts.

Marco Trerotola, Kirat K. Ganguly, Ladan Fazli, Carmine Fedele, Huimin Lu, Anindita Dutta, Qin Liu, Tiziana De Angelis, Luke W. Riddell, Natalia A. Riobo, Martin E. Gleave, Amina Zoubeidi, Richard G. Pestell, Dario C. Altieri, and Lucia R. Languino.

Oncotarget. 2015 Jun 10;6(16):14318-28.

PMID: 26015409

Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapy.

Rebecca Lamb, Marco Fiorillo, Amy Chadwick, Bela Ozsvari, Kimberly J. Reeves, Duncan L. Smith, Robert B. Clarke, Sacha J. Howell, Anna Rita Cappello, Ubaldo E. Martinez-Outschoorn, Maria Peiris-Pagès, Federica Sotgia, and Michael P. Lisanti.

Oncotarget. 2015 Jun 10;6(16):14005-25.

PMID: 26087309

HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells.

Lisha Xiang, Daniele M. Gilkes, Hongxia Hu, Weibo Luo, John W. Bullen, Houjie Liang and Gregg L. Semenza.

Oncotarget. 2015 May 20;6(14):11768-78.

PMID: 26059435

Loss of Wave1 gene defines a subtype of lethal prostate cancer.

Adam G. Sowalsky, Rebecca Sager, Rachel J. Schaefer, Gennady Bratslavsky, Pier Paolo Pandolfi, Steven P. Balk, Leszek Kotula.

Oncotarget. 2015 May 20;6(14):12383-91.

PMID: 25906751

Meta-analysis of organ-specific differences in the structure of the immune infiltrate in major malignancies.

Gautier Stoll, Gabriela Bindea, Bernhard Mlecnik, Jérôme Galon, Laurence Zitvogel, and Guido Kroemer.

Oncotarget. 2015 May 20;6(14):11894-909.

PMID: 26059437

SRC family kinase (SFK) inhibition reduces rhabdomyosarcoma cell growth in vitro and in vivo and triggers p38 MAP kinase-mediated differentiation.

Nadia Casini, Iris Maria Forte, Gianmarco Mastrogiovanni, Francesca Pentimalli, Adriano Angelucci, Claudio Festuccia, Valentina Tomei, Elisa Ceccherini, Domenico Di Marzo, Silvia Schenone, Maurizio Botta, Antonio Giordano, Paola Indovina.

Oncotarget. 2015 May 20;6(14):12421-35.

PMID: 25762618

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity.

Jessica Frankum, Pavel Moudry, Rachel Brough, Zdenek Hodny, Alan Ashworth, Jiri Bartek, and Christopher J. Lord

Oncotarget. 2015 May 10;6(13):10746-58.

PMID: 25883215

Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells.

Maria Peiris-Pagès, Federica Sotgia, and Michael P. Lisanti

Oncotarget. 2015 May 10;6(13):10728-45.

PMID: 25915429

New therapeutic approach to heart failure due to myocardial infarction based on targeting growth hormone-releasing hormone receptor.

Rosemeire M. Kanashiro-Takeuchi, Luca Szalontay, Andrew V. Schally, Lauro M. Takeuchi, Petra Popovics, Miklos Jaszberenyi, Irving Vidaurre, Marta Zarandi, Ren-Zhi Cai, Norman L. Block, Joshua M. Hare, Ferenc G. Rick,

Oncotarget. 2015 Apr 30;6(12):9728-39.

PMID: 25797248

Polypharmacology of small molecules targeting the ubiquitin–proteasome and ubiquitin-like systems.

Ivano Amelio, Vivien Landré, Richard A. Knight, Andrey Lisitsa, Gerry Melino, and Alexey V. Antonov

Oncotarget. 2015 Apr 30;6(12):9646-56.

PMID: 25991664

Deregulation of dicer and mir-155 expression in liposarcoma.

Bruno Vincenzi, Michele Iuliani, Alice Zoccoli, Francesco Pantano, Marco Fioramonti, Delia De Lisi, Anna Maria Frezza, Carla Rabitti, Giuseppe Perrone, Andrea Onetti Muda, Antonio Russo, Antonio Giordano, Daniele Santini, Angelo Paolo Dei Tos, Giuseppe Tonini.

Oncotarget. 2015 Apr 30;6(12):10586-91.

PMID: 25888631

Quantification of cellular viability by automated microscopy and flow cytometry.

Allan Sauvat, Yidan Wang, Florian Segura, Sabrina Spaggiari, Kevin Müller, Heng Zhou, Lorenzo Galluzzi, Oliver Kepp, Guido Kroemer

Oncotarget. 2015 Apr 20;6(11):9467-75.

PMID: 25816366

Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis.

Mathew C. Casimiro, Gabriele Di Sante, Marco Crosariol, Emanuele Loro, William Dampier, Adam Ertel, Zuoren Yu, Elizabeth A. Saria, Alexandros Papanikolaou, Zhiping Li, Chenguang Wang, Sankar Addya, Michael P. Lisanti, Paolo Fortina, Robert D. Cardiff, Aydin Tozeren, Erik S. Knudsen, Andrew Arnold, and Richard G. Pestell

Oncotarget. 2015 Apr 20;6(11):8525-38.

PMID: 25940700

Clostridium novyi-NT can cause regression of orthotopically implanted glioblastomas in rats.

Verena Staedtke, Ren-Yuan Bai, Weiyun Sun, Judy Huang, Kathleen Kazuko Kibler, Betty M. Tyler, Gary L. Gallia, Kenneth Kinzler, Bert Vogelstein, Shibin Zhou and Gregory J. Riggins.

Oncotarget. 2015 Mar 20;6(8):5536-46.

PMID: 25849940

Structural variation discovery in the cancer genome using next generation sequencing: computational solutions and perspectives.

Biao Liu, Jeffrey M. Conroy, Carl D. Morrison, Adekunle O. Odunsi, Maochun Qin, Lei Wei, Donald L. Trump, Candace S. Johnson, Song Liu and Jianmin Wang.

Oncotarget. 2015 Mar 20;6(8):5477-89.

PMID: 25849937

miR-27a and miR-27a* contribute to metastatic properties of osteosarcoma cells.

Zaidoun Salah, Rand Arafeh, Vadim Maximov, Marco Galasso, Saleh Khawaled, Samah Abou-Sharieha, Stefano Volinia, Kevin B. Jones, Carlo M. Croce, Rami I. Aqeilan.

Oncotarget. 2015 Mar 10;6(7):4920-35.

PMID: 25749032

Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction.

Rebecca Lamb, Hannah Harrison, Duncan L. Smith, Paul A. Townsend, Thomas Jackson, Bela Ozsvari, Ubaldo E. Martinez-Outschoorn, Richard G. Pestell, Anthony Howell, Michael P. Lisanti, and Federica Sotgia.

Oncotarget. 2015 Mar 10;6(7):4585-601.

PMID: 25671304

Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: Treating cancer like an infectious disease.

Rebecca Lamb, Bela Ozsvari, Camilla L. Lisanti, Herbert B. Tanowitz, Anthony Howell, Ubaldo E. Martinez-Outschoorn, Federica Sotgia, and Michael P. Lisanti.

Oncotarget. 2015 Mar 10;6(7):4569-84.

PMID: 25625193

p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia.

Alper Yetil, Benedict Anchang, Arvin M. Gouw, Stacey J. Adam, Tahera Zabuawala, Ramya Parameswaran, Jan van Riggelen, Sylvia Plevritis, Dean W. Felsher.

Oncotarget. 2015 Feb 28;6(6):3563-77.

PMID: 25784651

Graphene oxide selectively targets cancer stem cells, across multiple tumor types: Implications for non-toxic cancer treatment, via “differentiation-based nano-therapy”.

Marco Fiorillo, Andrea F. Verre, Maria Iliut, Maria Peiris-Pagés, Bela Ozsvari, Ricardo Gandara, Anna Rita Cappello, Federica Sotgia, Aravind Vijayaraghavan, and Michael P. Lisanti.

Oncotarget. 2015 Feb 28;6(6):3553-62.

PMID: 25708684

Protease nexin 1 induces apoptosis of prostate tumor cells through inhibition of X-chromosome-linked inhibitor of apoptosis protein.

Chad M. McKee, Yunchuan Ding, Jianfeng Zhou, Chunrui Li, Liang Huang, Xiangke Xin, Jing He, Joshua E. Allen, Wafik S. El-Deiry, Yunhong Cao, Ruth J. Muschel, Danmei Xu.

Oncotarget. 2015 Feb 28;6(6):3784-96.

PMID: 25686839

Intravital imaging reveals p53-dependent cancer cell death induced by phototherapy via calcium signaling.

Carlotta Giorgi, Massimo Bonora, Sonia Missiroli, Federica Poletti, Fabian Galindo Ramirez, Giampaolo Morciano, Claudia Morganti, Pier Paolo Pandolfi, Fabio Mammano and Paolo Pinton.

Oncotarget. 2015 Jan 30;6(3):1435-45.

PMID: 25544762

Predicting response to HER2 kinase inhibition.

Jeff Settleman.

Oncotarget. 2015 Jan 20;6(2):588-9.

PMID: 25655645

Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer.

Frank P. Vendetti, Michael Topper, Peng Huang, Irina Dobromilskaya, Hariharan Easwaran, John Wrangle, Stephen B. Baylin, J. T. Poirier, Charles M. Rudin

Oncotarget. 2015 Jan 1;6(1):56-70.

PMID: 25474141

2014 Papers

TAp73 promotes anabolism.

Ivano Amelio, Alexey A. Antonov, Maria Valeria Catani, Renato Massoud, Francesca Bernassola, Richard A. Knight, Gerry Melino, and Alessandro Rufini.

Oncotarget. 2014 Dec 30;5(24):12820-934.

PMID: 25514460

The angular structure of ONC201, a TRAIL pathway-inducing compound, determines its potent anti-cancer activity.

Jessica Wagner, Christina Leah Kline, Richard S. Pottorf, Bhaskara Rao Nallaganchu, Gary L. Olson, David T. Dicker, Joshua E. Allen, Wafik S. El-Deiry.

Oncotarget. 2014 Dec 30;5(24):12728-37.

PMID: 25587031

MYC regulates the non-coding transcriptome.

Jonathan R. Hart, Thomas C. Roberts, Marc S. Weinberg, Kevin V. Morris, and Peter K. Vogt.

Oncotarget. 2014 Dec 30;5(24):12543-54.

PMID: 25587025

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype.

Lisha Xiang, Daniele M. Gilkes, Hongxia Hu, Naoharu Takano, Weibo Luo, Haiquan Lu, John W. Bullen, Debangshu Samanta, Houjie Liang and Gregg L. Semenza.

Oncotarget. 2014 Dec 30;5(24):12509-27.

PMID: 25587023

Classification of current anticancer immunotherapies.

Lorenzo Galluzzi,, Erika Vacchelli, José-Manuel Bravo-San Pedro, Aitziber Buqué, Laura Senovilla, Elisa Elena Baracco, Norma Bloy, Francesca Castoldi,, Jean-Pierre Abastado, Patrizia Agostinis, Ron N. Apte, Fernando Aranda, Maha Ayyoub, Philipp Beckhove, Jean-Yves Blay, Laura Bracci, Anne Caignard, Chiara Castelli, Federica Cavallo, Estaban Celis, Vincenzo Cerundolo, Aled Clayton, Mario P. Colombo, Lisa Coussens, Madhav V. Dhodapkar, Alexander M. Eggermont, Douglas T. Fearon, Wolf H. Fridman, Jitka Fučíková, Dmitry I. Gabrilovich, Jérôme Galon, Abhishek Garg, François Ghiringhelli, Giuseppe Giaccone, Eli Gilboa, Sacha Gnjatic, Axel Hoos, Anne Hosmalin, Dirk Jäger, Pawel Kalinski, Klas Kärre, Oliver Kepp, Rolf Kiessling, John M. Kirkwood, Eva Klein, Alexander Knuth, Claire E. Lewis, Roland Liblau, Michael T. Lotze, Enrico Lugli, Jean-Pierre Mach, Fabrizio Mattei, Domenico Mavilio, Ignacio Melero, Cornelis J. Melief, Elizabeth A. Mittendorf, Lorenzo Moretta, Adekunke Odunsi, Hideho Okada, Anna Karolina Palucka, Marcus E. Peter, Kenneth J. Pienta, Angel Porgador, George C. Prendergast, Gabriel A. Rabinovich, Nicholas P. Restifo, Naiyer Rizvi, Catherine Sautès-Fridman, Hans Schreiber, Barbara Seliger, Hiroshi Shiku, Bruno Silva-Santos, Mark J. Smyth, Daniel E. Speiser, Radek Spisek, Pramod K. Srivastava, James E. Talmadge, Eric Tartour, Sjoerd H. Van Der Burg, Benoît J. Van Den Eynde, Richard Vile, Hermann Wagner, Jeffrey S. Weber, Theresa L. Whiteside, Jedd D. Wolchok, Laurence Zitvogel, Weiping Zou and Guido Kroemer.

Oncotarget. 2014 Dec 30;5(24):12472-508.

PMID: 25537519

Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition.

Rebecca Lamb, Hannah Harrison, James Hulit, Duncan L. Smith, Michael P. Lisanti, and Federica Sotgia.

Oncotarget. 2014 Nov 30;5(22):11029-37.

PMID: 25415228

Bioinformatics analysis of the serine and glycine pathway in cancer cells.

Alexey Antonov, Massimiliano Agostini, Maria Morello, Marilena Minieri, Gerry Melino, and Ivano Amelio.

Oncotarget. 2014 Nov 30;5(22):11004-13.

PMID: 25436979

p53 status as effect modifier of the association between pre-treatment fasting glucose and breast cancer outcomes in non diabetic, HER2 positive patients treated with trastuzumab.

Patrizia Vici, Francesca Sperati, Marcello Maugeri-Saccà, Elisa Melucci, Anna Di Benedetto, Luigi Di Lauro, Laura Pizzuti, Domenico Sergi, Irene Terrenato, Luca Esposito, Carmelina Antonella Iannuzzi, Raffaella Pasquale, Claudio Botti, Barbara Fuhrman, Antonio Giordano, Marcella Mottolese, and Maddalena Barba.

Oncotarget. 2014 Nov 15;5(21):10382-92.

PMID: 25071015

Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation.

Ying Yan, Ashley L. Hein, Asserewou Etekpo, Katrina M. Burchett, Chi Lin, Charles A. Enke, Surinder K. Batra, Kenneth H. Cowan, Michel M. Ouellette.

Oncotarget. 2014 Nov 15;5(21):10251-70.

PMID: 25344910

Expression of stemness genes in primary breast cancer tissues: the role of SOX2 as a prognostic marker for detection of early recurrence.

Mauro Finicelli, Giovanni Benedetti, Tiziana Squillaro, Barbara Pistilli, Andrea Marcellusi, Paola Mariani, Alfredo Santinelli, Luciano Latini, Umberto Galderisi, Antonio Giordano.

Oncotarget. 2014 Oct 30;5(20):9678-88.

PMID: 25127259

Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression.

Claudia A. Benavente, David Finkelstein, Dianna A. Johnson, Jean-Christophe Marine, Ruth Ashery-Padan, Michael A. Dyer.

Oncotarget. 2014 Oct 30;5(20):9594-608.

PMID: 25338120

Selected drugs that inhibit DNA methylation can preferentially kill p53 deficient cells.

Lan Yi, Yvonne Sun, Arnold Levine.

Oncotarget. 2014 Oct 15;5(19):8924-36.

PMID: 25238040

In vivo quantification and perturbation of Myc-Max interactions and the impact on oncogenic potential.

Philipp Raffeiner, Ruth Röck, Andrea Schraffl, Markus Hartl, Jonathan R. Hart, Kim D. Janda, Peter K. Vogt, Eduard Stefan and Klaus Bister.

Oncotarget. 2014 Oct 15;5(19):8869-78.

PMID: 25326649

Hypoxia-inducible factors enhance glutamate signaling in cancer cells.

Hongxia Hu, Naoharu Takano, Lisha Xiang, Daniele M. Gilkes, Weibo Luo, and Gregg L. Semenza.

Oncotarget. 2014 Oct 15;5(19):8853-68.

PMID: 25326682

Oncogene addiction: resetting the safety switch?

Yulin Li, Peter S. Choi, and Dean W. Felsher.

Oncotarget. 2014 Sep 30;5(18):7986-7. No abstract available.

PMID: 25275297

Screening for E3-Ubiquitin ligase inhibitors: challenges and opportunities

Vivien Landré, Barak Rotblat, Sonia Melino, Francesca Bernassola, and Gerry Melino.

Oncotarget. 2014 Sep 30;5(18):7988-8013.

PMID: 25237759

The reverse warburg effect in osteosarcoma

Federica Sotgia, Ubaldo E. Martinez-Outschoorn, and Michael P. Lisanti.

Oncotarget. 2014 Sep 30;5(18):7982-3.

PMID: 25478627

Co-ordination of cell cycle, migration and stem cell-like activity in breast cancer

Rebecca Lamb, Michael P. Lisanti, Robert B. Clarke, and Göran Landberg.

Oncotarget. 2014 Sep 30;5(18):7833-42.

PMID: 25277201

Metabolic effect of TAp63α: enhanced glycolysis and pentose phosphate pathway, resulting in increased antioxidant defense

Angelo D’Alessandro, Ivano Amelio, Celia R. Berkers, Alexey Antonov, Karen H. Vousden, Gerry Melino, and Lello Zolla.

Oncotarget. 2014 Sep 30;5(18):7722-33.

PMID: 25229745

Overcoming EMT-associated resistance to anti-cancer drugs via Src/FAK pathway inhibition.

Catherine Wilson, Katrina Nicholes, Daisy Bustos, Eva Lin, Qinghua Song, Jean-Philippe Stephan, Donald S. Kirkpatrick and Jeff Settleman.

Oncotarget. 2014 Sep 15;5(17):7328-41.

PMID: 25193862

Transcribed ultraconserved noncoding RNAs (T-UCR) are involved in Barrett's esophagus carcinogenesis.

Matteo Fassan, Luigi Dall’Olmo, Marco Galasso, Chiara Braconi, Marco Pizzi, Stefano Realdon, Stefano Volinia, Nicola Valeri, Pierluigi Gasparini, Raffaele Baffa, Rhonda F. Souza, Caterina Vicentini, Edoardo D’Angelo, Jan Bornschein, Gerard J. Nuovo, Giovanni Zaninotto, Carlo M. Croce and Massimo Rugge.

Oncotarget. 2014 Aug 30;5(16):7162-71.

PMID: 25216530

FAS/FASL are dysregulated in chordoma and their loss-of-function impairs zebrafish notochord formation.

Luca Ferrari, Anna Pistocchi1, Laura Libera, Nicola Boari, Pietro Mortini, Gianfranco Bellipanni, Antonio Giordano, Franco Cotelli, Paola Riva

Oncotarget. 2014 Jul 30;5(14):5712-24.

PMID: 25071022

Circulating miR-148b and miR-133a as biomarkers for breast cancer detection.

Jie Shen, Qiang Hu, Michael Schrauder, Li Yan, Dan Wang, Leonardo Medico, Yuqing Guo, Song Yao, Qianqian Zhu, Biao Liu, Maochun Qin, Matthias W. Beckmann, Peter A. Fasching, Reiner Strick, Candace S. Johnson, Christine B. Ambrosone, Hua Zhao, Song Liu.

Oncotarget. 2014 Jul 30;5(14):5284-94.

PMID: 25051376

Structural basis of nSH2 regulation and lipid binding in PI3Kα.

Michelle S. Miller, Oleg Schmidt-Kittler, David M. Bolduc, Evan T. Brower, Daniele Chaves-Moreira, Marc Allaire, Kenneth W. Kinzler, Ian G. Jennings, Philip E. Thompson, Philip A. Cole, L. Mario Amzel, Bert Vogelstein and Sandra B. Gabelli.

Oncotarget. 2014 Jul 30;5(14):5198-208.

PMID: 25105564

Immunogenic cell death inducers as anticancer agents.

Oliver Kepp, Laura Senovilla, and Guido Kroemer.

Oncotarget. 2014 Jul 30;5(14):5190-1. No abstract available.

PMID: 25114034

An interferon signature identified by RNA-sequencing of mammary tissues varies across the estrous cycle and is predictive of metastasis-free survival.

Antoine M. Snijders, Sasha Langley, Jian-Hua Mao, Sandhya Bhatnagar, Kathleen A. Bjornstad, Chris J. Rosen, Alvin Lo, Yurong Huang, Eleanor A. Blakely, Gary H. Karpen, Mina J. Bissell and Andrew J. Wyrobek.

Oncotarget. 2014 Jun 30;5(12):4011-25.

PMID: 24994117

Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma.

Kathleen M. Capaccione, Xuehui Hong, Katherine M. Morgan, Wenyu Liu, J. Michael Bishop, LianXin Liu, Elke Markert, Malik Deen, Christine Minerowicz, Joseph R. Bertino, Thaddeus Allen, and Sharon R. Pine.

Oncotarget. 2014 Jun 15;5(11):3636-50.

PMID: 25004243

17β-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer cells.

Paul K. Wright, Sarah Bowen Jones, Nicholas Ardern, Rebecca Ward, Robert B. Clarke, Federica Sotgia, Michael P. Lisanti, Goran Landberg, and Rebecca Lamb.

Oncotarget. 2014 May 30;5(10):3055-65.

PMID: 24931391

Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity.

Lavinia Raimondi, Nicola Amodio, Maria Teresa Di Martino, Emanuela Altomare, Marzia Leotta, Daniele Caracciolo, Annamaria Gullà, Antonino Neri, Simona Taverna, Patrizia D’Aquila, Riccardo Alessandro, Antonio Giordano, Pierosandro Tagliaferri and Pierfrancesco Tassone.

Oncotarget. 2014 May 30;5(10):3039-54.

PMID: 24839982

Apoptotic circulating tumor cells (CTCs) in the peripheral blood of metastatic colorectal cancer patients are associated with liver metastasis but not CTCs.

Joshua E. Allen, Bikramajit Singh Saroya, Miriam Kunkel, David T. Dicker, Avisnata Das, Kristi L. Peters, Jamal Joudeh, Junjia Zhu, and Wafik S. El-Deiry.

Oncotarget. 2014 Apr 15;5(7):1753-60.

PMID: 24334302

The NLR-related protein NWD1 is associated with prostate cancer and modulates androgen receptor signaling.

Ricardo G. Correa, Maryla Krajewska, Carl F. Ware, Motti Gerlic, and John C. Reed.

Oncotarget. 2014 Mar 30;5(6):1666-82.

PMID: 24681825

p63 transcriptionally regulates the expression of matrix metallopeptidase 13.

Ivana Celardo, Alexey Antonov, Ivano Amelio, Margherita Annicchiarico-Petruzzelli, and Gerry Melino.

Oncotarget. 2014 Mar 30;5(6):1279-89.

PMID: 24658133

Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner.

Joshua Armenia, Linda Fabris, Francesca Lovat, Stefania Berton, Ilenia Segatto, Sara D’Andrea, Cristina Ivan, Luciano Cascione, George A. Calin, Carlo M. Croce, Alfonso Colombatti, Andrea Vecchione, Barbara Belletti and Gustavo Baldassarre.

Oncotarget. 2014 Mar 15;5(5):1185-97.

PMID: 24727437

microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers.

Pierluigi Gasparini, Luciano Cascione, Matteo Fassan, Francesca Lovat, Gulnur Guler, Serdar Balci, Cigdem Irkkan, Carl Morrison, Carlo M. Croce, Charles L. Shapiro, Kay Huebner.

Oncotarget. 2014 Mar 15;5(5):1174-84.

PMID: 24632568

Dopamine signaling: target in glioblastoma.

Jiri Bartek, Zdenek Hodny

Oncotarget. 2014 Mar 15;5(5):1116-7. No abstract available.

PMID: 24657925

LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer.

Francesca Lovat, Hideshi Ishii, Monica Schiappacassi, Matteo Fassan, Mattia Barbareschi, Enzo Galligioni, Pierluigi Gasparini, Gustavo Baldassarre, Carlo M. Croce and Andrea Vecchione.

Oncotarget. 2014 Feb 28;5(4):970-7.

PMID: 24448468

A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor.

Russell T Burke, Sarah Meadows, Marc M Loriaux, Kevin S. Currie, Scott A. Mitchell, Patricia Maciejewski, Astrid S. Clarke, Julie A. Dipaolo, Brian J. Druker, Brian J. Lannutti ,and Stephen E. Spurgeon.

Oncotarget. 2014 Feb 28;5(4):908-15.

PMID: 24659719

A novel peptide that inhibits E2F transcription and regresses prostate tumor xenografts.

Xiaoqi Xie, Nitu Bansal, Tazeem Shaik, John E. Kerrigan, Tamara Minko, Olga Garbuzenko,Emine Ercikan Abali, Nadine Johnson-Farley, Debabrata Banerjee, Kathleen W. Scotto and Joseph R Bertino.

Oncotarget. 2014 Feb 28;5(4):901-7.

PMID: 24658650

Role of aberrant PI3K pathway activation in gallbladder tumorigenesis.

Andrea Lunardi, Kaitlyn A. Webster, Antonella Papa, Bhavik Padmani, John G. Clohessy, Roderick T. Bronson and Pier Paolo Pandolfi.

Oncotarget. 2014 Feb 28;5(4):894-900.

PMID: 24658595

Serum microRNA expression patterns that predict early treatment failure in prostate cancer patients.

Prashant K. Singh, Leah Preus, Qiang Hu, Li Yan, Mark D. Long, Carl D. Morrison, Mary Nesline, Candace S. Johnson, Shahriar Koochekpour, Manish Kohli, Song Liu, Donald L. Trump, Lara E Sucheston-Campbell, and Moray J. Campbell.

Oncotarget. 2014 Feb 15;5(3):824-40.

PMID: 24583788

Large scale integration of drug-target information reveals poly-pharmacological drug action mechanisms in tumor cell line growth inhibition assayss.

Richard Knight, Mikhail Gostev, Sergei Ilisavskii, Anne E Willis, Gerry Melino, and Alexey V Antonov.

Oncotarget. 2014 Feb 15;5(3):659-66.

PMID: 24553133

Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers.

Huili Li, Katherine B. Chiappinelli, Angela A. Guzzetta, Hariharan Easwaran, Ray-Whay Chiu Yen, Rajita Vatapalli, Michael J. Topper, Jianjun Luo, Roisin M. Connolly, Nilofer S. Azad, Vered Stearns, Drew M. Pardoll, Nancy Davidson, Peter A. Jones, Dennis J. Slamon, Stephen B. Baylin, Cynthia A. Zahnow, Nita Ahuja.

Oncotarget. 2014 Feb 15;5(3):587-98.

PMID: 24583822

RB1 gene inactivation by chromothripsis in human retinoblastoma.

Justina McEvoy, Panduka Nagahawatte, David Finkelstein, Jennifer Richards-Yutz, Marcus Valentine, Jing Ma, Charles Mullighan, Guangchun Song, Xiang Chen, Matthew Wilson, Rachel Brennan, Stanley Pounds, Jared Becksfort, Robert Huether, Charles Lu, Robert S. Fulton, Lucinda L. Fulton, Xin Hong, David J. Dooling, Kerri Ochoa, Elaine R. Mardis, Richard K.Wilson, John Easton, Jinghui Zhang, James R. Downing, Arupa Ganguly, and Michael A. Dyer.

Oncotarget. 2014 Jan 30;5(2):438-50.

PMID: 24509483

2013 Papers

Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers.

Barak Rotblat, Thomas G. P. Grunewald, Gabriel Leprivier, Gerry Melino, and Richard A. Knight.

Oncotarget. 2013 Dec;4(12):2577-90.

PMID: 24342878

6p22.3 amplification as a biomarker and potential therapeutic target of advanced stage bladder cancer.

He Shen, Carl D. Morrison, Jianmin Zhang, Willie Underwood III, Nuo Yang, Costa Frangou, Kevin Eng, Karen Head, Roni J. Bollag, Sravan K. Kavuri, Amyn M. Rojiani, Yingwei Li, Li Yan, Annette Hill, Anna Woloszynska-Read, Jianmin Wang, Song Liu, Donald L. Trump, and Candace S. Johnson.

Oncotarget. 2013 Nov;4(11):2124-34.

PMID: 24231253

Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine.

John Wrangle, Wei Wang, Alexander Koch, Hariharan Easwaran, Helai P. Mohammad, Xiaoyu Pan,Frank Vendetti, Wim VanCriekinge, Timothy DeMeyer, Zhengzong Du, Princy Parsana, Kristen Rodgers, Ray-Whay Yen, Cynthia A. Zahnow, Janis M. Taube, Julie R. Brahmer, Scott S. Tykodi, Keith Easton, Richard D. Carvajal, Peter A. Jones, Peter W. Laird, Daniel J. Weisenberger, Salina Tsai, Rosalyn A. Juergens, Suzanne L. Topalian, Charles M. Rudin, Malcolm V. Brock, Drew Pardoll, and Stephen B. Baylin.

Oncotarget. 2013 Nov;4(11):2067-79.

PMID: 24162015

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals.

Sabine Becker-Weimann, Gaofeng Xiong, Saori Furuta, Ju Han, Irene Kuhn, Uri-David Akavia, Dana Pe’er, Mina J Bissell, Ren Xu.

Oncotarget. 2013 Nov;4(11):2010-20.

PMID: 24243820

Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX.

Marissa V Powers, Melanie Valenti, Susana Miranda, Alison Maloney, Suzanne A. Eccles, George Thomas, Paul A Clarke and Paul Workman.

Oncotarget. 2013 Nov;4(11):1963-75.

PMID: 24185264

Computational methods for detecting copy number variations in cancer genome using next generation sequencing: principles and challenges.

Biao Liu, Carl D. Morrison, Candace S. Johnson, Donald L. Trump, Maochun Qin, Jeffrey C. Conroy, Jianmin Wang, and Song Liu.

Oncotarget. 2013 Nov;4(11):1868-81. Review.

PMID: 24240121

The discovery of potent ribosomal S6 kinase inhibitors by high-throughput screening and structure-guided drug design.

Sylvain Couty, Isaac M. Westwood, Andrew Kalusa, Celine Cano, Jon Travers, Kathy Boxall, Chiau Ling Chow, Sam Burns, Jessica Schmitt, Lisa Pickard, Caterina Barillari, P. Craig McAndrew, Paul A. Clarke, Spiros Linardopoulos, Roger J. Griffin, G. Wynne Aherne, Florence I. Raynaud, Paul Workman, Keith Jones, Rob L.M. van Montfort.

Oncotarget. 2013 Oct;4(10):1647-61.

PMID: 24072592

5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft.

Alexandra Borodovsky, Vafi Salmasi, Sevin Turcan, Armida W. M. Fabius,Gilson S. Baia, Charles G. Eberhart, Jon D. Weingart, Gary L. Gallia, Stephen B. Baylin, Timothy A. Chan, and Gregory J. Riggins.

Oncotarget. 2013 Oct;4(10):1737-47.

PMID: 24077805

Substantial expression of luteinizing hormone-releasing hormone (LHRH) receptor type I in human uveal melanoma.

Andrea Treszl, Zita Steiber, Andrew V. Schally, Norman L Block, Balazs Dezso, Gabor Olah, Bernadett Rozsa, Klara Fodor, Armin Buglyo, Janos Gardi, Andras Berta and Gabor Halmos.

Oncotarget. 2013 Oct;4(10):1721-8.

PMID: 24077773

Lysine-specific modifications of p53: a matter of life and death?

Diana Marouco, Alexander V Garabadgiu, Gerry Melino, and Nick A Barlev.

Oncotarget. 2013 Oct;4(10):1556-71.

PMID: 24298606

Cytokine-induced 'bystander' senescence in DDR and immuno-surveillance.

Zdenek Hodny, Sona Hubackova, Jiri Bartek.

Oncotarget. 2013 Oct;4(10):1552-3. No abstract available.

PMID: 24145286

Isolation and genome-wide expression and methylation characterization of CD31+ cells from normal and malignant human prostate tissue.

Wei Luo, Qiang Hu, Dan Wang, Kristin K. Deeb,Yingyu Ma, Carl D. Morrison, Song Liu, Candace S. Johnson and Donald L. Trump.

Oncotarget. 2013 Sep;4(9):1472-83.

PMID: 23978847

DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity

Tatiana N Moiseeva, Andrew Bottrill, Gerry Melino, and Nickolai A Barlev.

Oncotarget. 2013 Sep;4(9):1338-48.

PMID: 23907514

Kinase inhibitor therapy in CML: it's what's inside that counts.

Christopher A. Eide, Brian J. Druker, Thomas O’Hare.

Oncotarget. 2013 Sep;4(9):1332-3. No abstract available.

PMID: 23934763

Combining trail with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling.

Grazia Saturno, Melanie Valenti, Alexis De Haven Brandon, George V. Thomas, Suzanne Eccles, Paul A. Clarke, and Paul Workman.

Oncotarget. 2013 Aug;4(8):1185-98.

PMID: 23852390

Cancer Metabolism: New Validated Targets for Drug Discovery.

Federica Sotgia, Ubaldo E. Martinez-Outschoorn, and Michael P Lisanti

Oncotarget. 2013 Aug;4(8):1309-16.

PMID: 23896568

Disruption of Myc-Max heterodimerization with improved cell-penetrating analogs of the small molecule 10074-G5.

Huabo Wang, Jay Chauhan, Angela Hu, Kelsey Pendleton, Jeremy L. Yap, Philip E. Sabato, Jace W. Jones, Mariarita Perri, Jianshi Yu, Erika Cione, Maureen A. Kane, Steven Fletcher, and Edward V. Prochownik,.

Oncotarget. 2013 Jun;4(6):936-47.

PMID: 23801058

Acetylation of the Cell-Fate Factor Dachshund Determines p53 Binding and Signaling Modules in Breast Cancer.

Ke Chen, Kongming Wu, Michael Gormley, Adam Ertel, Wei Zhang, Jie Zhou, Gabriele DiSante, Zhiping Li, Hallgeir Rui, Andrew A. Quong, Steven B. McMahon, Haiteng Deng, Michael P. Lisanti, Chenguang Wang, and Richard G. Pestell.

Oncotarget. 2013 Jun;4(6):923-35.

PMID: 23798621

pRb controls estrogen receptor alpha protein stability and activity.

Isabella Caligiuri, Giuseppe Toffoli, Antonio Giordano, and Flavio Rizzolio.

Oncotarget. 2013 Jun;4(6):875-83.

PMID: 23900261

Cross-species genomic and epigenomic landscape of retinoblastoma.

Claudia A. Benavente, Justina D. McEvoy, David Finkelstein, Lei Wei, Guolian Kang, Yong-Dong Wang, Geoffrey Neale, Susan Ragsdale, Virginia Valentine, Armita Bahrami, Jamshid Temirov, Stanley Pounds, Jinghui Zhang, and Michael A. Dyer.

Oncotarget. 2013 Jun;4(6):844-59.

PMID: 23765217

Powerful inhibition of experimental human pancreatic cancers by receptor targeted cytotoxic LH-RH analog AEZS-108.

Karoly Szepeshazi, Andrew V. Schally,, Norman L. Block, Gabor Halmos, Mehrdad Nadji, Luca Szalontay, Irving Vidaurre, Andrew Abi-Chaker, Ferenc G. Rick,.

Oncotarget. 2013 May;4(5):751-60.

PMID: 23744510

Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the (V600E)BRAF oncogene.

Arnaldur Hall, Kathrine Damm Meyle, Marina Krarup Lange, Martin Klima, May Sanderhoff, Christina Dahl, Cecilie Abildgaard, Katrine Thorup, Seyed Moein Moghimi, Per Bo Jensen, Jiri Bartek, Per Guldberg and Claus Christensen.

Oncotarget. 2013 Apr;4(4):584-99.

PMID: 23603840

Exomic sequencing of four rare central nervous system tumor types.

Chetan Bettegowda, Nishant Agrawal, Yuchen Jiao, Yuxuan Wang, Laura D. Wood, Fausto J. Rodriguez, Ralph H. Hruban, Gary L. Gallia, Zev A. Binder, Callen J. Riggins, Vafi Salmasi, Gregory J. Riggins, Zachary J. Reitman, Ahmed Rasheed, Stephen Keir, Sueli Shinjo, Suely Marie, Roger McLendon, George Jallo, Bert Vogelstein, Darell Bigner, Hai Yan, Kenneth W. Kinzler and Nickolas Papadopoulos.

Oncotarget. 2013 Apr;4(4):572-83.

PMID: 23592488

Inhibition of U-87 MG glioblastoma by AN-152 (AEZS-108), a targeted cytotoxic analog of luteinizing hormone-releasing hormone.

Miklos Jaszberenyi, Andrew V. Schally,, Norman L. Block, Mehrdad Nadji, Irving Vidaurre, Luca Szalontay, Ferenc G. Rick.

Oncotarget. 2013 Mar;4(3):422-32.

PMID: 23518876

Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB.

Vasilisa Aksenova, Lidia Turoverova, Mikhail Khotin, Karl-Eric Magnusson, Eugene Tulchinsky, Gerry Melino, George P Pinaev, Nikolai Barlev, and Dmitri Tentler.

Oncotarget. 2013 Feb;4(2):362-72.

PMID: 23482348

DNA-intercalators causing rapid re-expression of methylated and silenced genes in cancer cells.

M. Zulfiquer Hossain, Megan A. Healey, Calvin Lee, Weijie Poh, Sashidhar R. Yerram, Kalpesh Patel, Nilofer S. Azad, James G. Herman, and Scott E. Kern.

Oncotarget. 2013 Feb;4(2):298-309.

PMID: 23593653

Preclinical analyses of intravesical chemotherapy for prevention of bladder cancer progression.

Joan C Delto, Takashi Kobayashi, Mitchell C Benson, James McKiernan, and Cory Abate-Shen.

Oncotarget. 2013 Feb;4(2):269-76.

PMID: 23563166

In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma.

Maria Teresa Di Martino, Annamaria Gullà, Maria Eugenia Gallo Cantafio, Marta Lionetti, Emanuela Leone, Nicola Amodio, Pietro Hiram Guzzi, Umberto Foresta, Francesco Conforti, Mario Cannataro, Antonino Neri, Antonio Giordano, Pierosandro Tagliaferri, and Pierfrancesco Tassone,.

Oncotarget. 2013 Feb;4(2):242-55.

PMID: 23479461

Calcein-effluxing human colon cancer cells are enriched for self-renewal capacity and depend on β-catenin.

Joshua E. Allen and Wafik S. El-Deiry.

Oncotarget. 2013 Feb;4(2):184-91.

PMID: 23468473

2012 Papers

The maintenance of epigenetic states by p53: the guardian of the epigenome.

Arnold J. Levine, Benjamin Greenbaum.

Oncotarget. 2012 Dec;3(12):1503-4. No abstract available.

PMID: 23237909

The promise of dual targeting Akt/mTOR signaling in lethal prostate cancer.

Nicolas Floc'h, and Cory Abate-Shen.

Oncotarget. 2012 Dec;3(12):1483-4.

PMID: 23242005

NRF2 and p53: Januses in cancer?

Barak Rotblat, Gerry Melino, and Richard A. Knight.

Oncotarget. 2012 Nov;3(11):1272-83.

PMID: 23174755

Genetic Induction of the Warburg Effect Inhibits Tumor Growth.

Federica Sotgia, Ubaldo E. Martinez-Outschoorn, Michael P. Lisanti.

Oncotarget. 2012 Nov;3(11):1266-7.

PMID: 23175502

The interfaces between signal transduction pathways: IGF-1/mTor, p53 and the Parkinson Disease pathway.

Arnold J. Levine, Chris R. Harris and Anna M. Puzio-Kuter.

Oncotarget. 2012 Nov;3(11):1301-7. No abstract available.

PMID: 23211569

Immunosurveillance against cancer-associated hyperploidy.

Laura Senovilla, Lorenzo Galluzzi, Guillermo Marino, Ilio Vitale, Maria Castedo, Guido Kroemer.

Oncotarget. 2012 Nov;3(11):1270-1. No abstract available.

PMID: 23174699

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma.

Nicola Amodio, Marzia Leotta, Dina Bellizzi, Maria Teresa Di Martino, Patrizia D’Aquila, Marta Lionetti, Fernanda Fabiani, Emanuela Leone, Anna Maria Gullà, Giuseppe Passarino, Michele Caraglia, Massimo Negrini, Antonino Neri, Antonio Giordano, Pierosandro Tagliaferri and Pierfrancesco Tassone.

Oncotarget. 2012 Oct;3(10):1246-58.

PMID: 23100393

Inhibiting the molecular evolution of cancer through HSP90.

Ana Sofia Martins, Faith E. Davies, Paul Workman.

Oncotarget. 2012 Oct;3(10):1054-6. No abstract available.

PMID: 23175477

Phenotypic screening reveals topoisomerase I as a breast cancer stem cell therapeutic target.

Fang Zhang, Kristi Rothermund, Sajithlal B. Gangadharan, Yves Pommier, Edward V. Prochownik, and John S. Lazo.

Oncotarget. 2012 Sep;3(9):998-1010.

PMID: 22948175

Antagonists of growth hormone-releasing hormone suppress in vivo tumor growth and gene expression in triple negative breast cancers.

Roberto Perez, Andrew V. Schally,, Irving Vidaurre, Ricardo Rincon, Norman L. Block, Ferenc G. Rick,.

Oncotarget. 2012 Sep;3(9):988-97.

PMID: 22941871

Mitochondrial Fission Induces Glycolytic Reprogramming in Cancer-Associated Myofibroblasts, Driving Stromal Lactate Production, and Early Tumor Growth.

Carmela Guido, Diana Whitaker-Menezes, Zhao Lin, Richard G. Pestell, Anthony Howell, Teresa A. Zimmers, Mathew C. Casimiro, Saveria Aquila, Sebastiano Ando, Ubaldo E. Martinez-Outschoorn, Federica Sotgia, and Michael P. Lisanti.

Oncotarget. 2012 Aug;3(8):798-810.

PMID: 22878233

Shock about heat shock in cancer.

Emmanuel de Billy, Jon Travers, Paul Workman.

Oncotarget. 2012 Aug;3(8):741-3.

PMID: 22964629

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas.

Yuchen Jiao, Patrick J. Killela, Zachary J. Reitman, B. Ahmed Rasheed, Christopher M. Heaphy, Roeland F. de Wilde, Fausto J. Rodriguez, Sergio Rosemberg , Sueli Mieko Oba-Shinjo, Suely Kazue Nagahashi Marie, Chetan Bettegowda, Nishant Agrawal, Eric Lipp, Christopher J. Pirozzi, Giselle Y. Lopez, Yiping He, Henry S. Friedman, Allan H. Friedman, Gregory J. Riggins, Matthias Holdhoff, Peter Burger, Roger E. McLendon, Darell D. Bigner, Bert Vogelstein, Alan K. Meeker, Kenneth W. Kinzler, Nickolas Papadopoulos, Luis A. Diaz, Jr., Hai Yan

Oncotarget. 2012 Jul;3(7):709-22.

PMID: 22869205

Receptor-targeted therapy of human experimental urinary bladder cancers with cytotoxic LH-RH analog AN-152 [AEZS- 108].

Karoly Szepeshazi , Andrew V. Schally,, Gunhild Keller, Norman L. Block, Daniel Benten, Gabor Halmos, Luca Szalontay, Irving Vidaurre, Miklos Jaszberenyi, Ferenc G. Rick,.

Oncotarget. 2012 Jul;3(7):686-99.

PMID: 22824624

A thymidylate synthase ternary complex-specific antibody, FTS, permits functional monitoring of fluoropyrimidines dosing.

Kalpesh Patel, Sashidhar R. Yerram, Nilofer A. Azad and Scott E. Kern.

Oncotarget. 2012 Jul;3(7):678-85.

PMID: 22824673

Properties of mechano-transduction via simulated microgravity and its effects on intracellular trafficking of VEGFR's.

Andrew Puca, Giuseppe Russo, Antonio Giordano.

Oncotarget. 2012 Apr;3(4):426-34.

PMID: 22566481

MiR-181b: new perspective to evaluate disease progression in chronic lymphocytic leukemia.

Rosa Visone, Angelo Veronese, Veronica Balatti, Carlo M. Croce.

Oncotarget. 2012 Feb;3(2):195-202.

PMID: 22350310

"Picolog," a synthetically-available bryostatin analog, inhibits growth of MYC-induced lymphoma in vivo.

Brian A. DeChristopher, Alice C. Fan, Dean W. Felsher, Paul A. Wender.

Oncotarget. 2012 Jan;3(1):58-66.

PMID: 22308267

2011 Papers

A novel dual signaling axis for NSP 5a3a induced apoptosis in head and neck carcinoma.

Luca D’Agostino and Antonio Giordano.

Oncotarget. 2011 Dec;2(12):1055-74.

PMID: 22170762

Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases.

Akshal S. Patel, Joshua E. Allen, David T. Dicker, Kristi L. Peters, Jonas M. Sheehan, Michael J. Glantz and Wafik S. El-Deiry.

Oncotarget. 2011 Oct;2(10):752-60.

PMID: 21987585

A chemical biology approach to developing STAT inhibitors: molecular strategies for accelerating clinical translation.

Erik A. Nelson, Sreenath V. Sharma, Jeffrey Settleman, and David A. Frank.

Oncotarget. 2011 Jun;2(6):518-24. Review.

PMID: 21680956

Phosphorylation of AKT: a mutational analysis.

Jonathan R. Hart, Peter K. Vogt.

Oncotarget. 2011 Jun;2(6):467-76.

PMID: 21670491

Mitochondrial compartmentalized protein folding and tumor cell survival.

Dario C. Altieri.

Oncotarget. 2011 Apr;2(4):347-51. Review.

PMID: 21555789

Potential therapeutic strategies to overcome acquired resistance to BRAF or MEK inhibitors in BRAF mutant cancers.

Ryan B. Corcoran, Jeffrey Settleman, Jeffrey A. Engelman.

Oncotarget. 2011 Apr;2(4):336-46. Review.

PMID: 21505228

A stressful life (or death): combinatorial proteotoxic approaches to cancer-selective therapeutic vulnerability.

Paul Workman, Faith E. Davies.

Oncotarget. 2011 Apr;2(4):277-80. No abstract available.

PMID: 21515932

IgH gene rearrangements as plasma biomarkers in Non- Hodgkin's lymphoma patients.

Jian He, Jian Wu, Yuchen Jiao, Nina Wagner-Johnston, Richard F. Ambinder, Luis A Diaz, Jr., Kenneth W Kinzler, Bert Vogelstein, and Nickolas Papadopoulos

Oncotarget. 2011 Mar;2(3):178-85.

PMID: 21399237

FAM190A rearrangements provide a multitude of individualized tumor signatures and neo-antigens in cancer.

Francesca Scrimieri, Eric S. Calhoun, Kalpesh Patel, Rigu Gupta,David L. Huso, Ralph H. Hruban, Scott E. Kern.

Oncotarget. 2011 Jan-Feb;2(1-2):69-75.

PMID: 21378412

A robust approach to enhance tumor-selective accumulation of nanoparticles.

Yuan Qiao, Xin Huang, Sridhar Nimmagadda, Renyuan Bai, Verena Staedtke, Catherine A. Foss, Ian Cheong, Matthias Holdhoff, Yoshinori Kato, Martin G. Pomper, Gregory J. Riggins, Kenneth W. Kinzler, Luis A. Diaz, Jr, Bert Vogelstein, Shibin Zhou.

Oncotarget. 2011 Jan-Feb;2(1-2):59-68.

PMID: 21378416

2010 Papers

The pursuit of oncotargets through understanding defective cell regulation.

Meng Qiao, Qian Shi, Arthur B. Pardee.

Oncotarget. 2010 Nov;1(7):544-51. Review.

PMID: 21317450

NSP 5a3a: a potential novel cancer target in head and neck carcinoma.

Luca D'agostino, Antonio Giordano.

Oncotarget. 2010 Oct;1(6):423-35.

PMID: 21311098

PI3Kα inhibitors that inhibit metastasis.

Oleg Schmidt-Kittler, Jiuxiang Zhu, Jian Yang, Guosheng Liu, William Hendricks, Christoph Lengauer, Sandra B. Gabelli, Kenneth W. Kinzler, Bert Vogelstein, David L. Huso, Shibin Zhou.

Oncotarget. 2010 Sep;1(5):339-48.

PMID: 21179398

Is miR-29 an oncogene or tumor suppressor in CLL?

Yuri Pekarsky, Carlo M. Croce.

Oncotarget. 2010 Jul;1(3):224-7.

PMID: 20936047

Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition.

Mounia Beloueche-Babari, Vaitha Arunan, L. Elizabeth Jackson, Nina Perusinghe, Swee Y. Sharp, Paul Workman, Martin O. Leach.

Oncotarget. 2010 Jul;1(3):185-97.

PMID: 21037799

The war on cancer: have we won the battle but lost the war?

Rachel Brennan, Sara Federico, Michael A. Dyer.

Oncotarget. 2010 Jun;1(2):77-83. No abstract available.

PMID: 20877440

Introducing Oncotarget.

Mikhail Blagosklonny, Andrei Gudkov.

Oncotarget. 2010 May;1(1):2.

PMCID: PMC4053540

Smooth muscle α-actin is a direct target of PLZF: effects on the cytoskeleton and on susceptibility to oncogenic transformation.

Jin Shi, Minghao Sun, Peter K. Vogt.

Oncotarget. 2010 May;1(1):9-21.

PMID: 20634973

Shape-shifting and tumor suppression by PLZF.

Robin M. Hobbs, Pier Paolo Pandolfi.

Oncotarget. 2010 May;1(1):3-5. No abstract available.

PMID: 21293049

Copyright © 2018 Impact Journals, LLC
Impact Journals is a registered trademark of Impact Journals, LLC