Comprehensive analysis of gene expression and DNA methylation datasets identify valuable biomarkers for rheumatoid arthritis progression

Infliction of proteotoxic stresses by impairment of the unfolded protein response or proteasomal inhibition as a therapeutic strategy for mast cell leukemia

A novel multiplex detection array revealed systemic complement activation in oral squamous cell carcinoma

Methylseleninic acid induces NAD(P)H:quinone oxidoreductase-1 expression through activation of NF-E2-related factor 2 in Chang liver cells

Effect of calcium salt of long-chain fatty acids and alfalfa supplementation on performance of Holstein bulls

Targeting the T-Lak cell originated protein kinase by OTS964 shrinks the size of power-law coded heterogeneous glioma stem cell populations

Increased risk of testis failure in testicular germ cell tumor survivors undergoing radiotherapy

Recombinant frizzled1 protein attenuated cardiac hypertrophy after myocardial infarction via the canonical Wnt signaling pathway

Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastoma

Quantitative analysis of prompt gamma ray imaging during proton boron fusion therapy according to boron concentration

Small non-coding RNA profiling in human biofluids and surrogate tissues from healthy individuals: description of the diverse and most represented species

Prognostic significance of ST6GalNAc-1 expression in patients with non-metastatic clear cell renal cell carcinoma

Schisandrol B and schisandrin B inhibit TGFβ1-mediated NF-κB activation via a Smad-independent mechanism

LITAF is a potential tumor suppressor in pancreatic cancer

Salvaged allogeneic hematopoietic stem cell transplantation for pediatric chemotherapy refractory acute leukemia

The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping

Suppression of FGFR3- and MYC-dependent oncogenesis by tubacin: association with HDAC6-dependent and independent activities

Hypoxia-inducible factor-1α activates transforming growth factor-β1/Smad signaling and increases collagen deposition in dermal fibroblasts

Systematic analysis of gene expression alterations and clinical outcomes of STAT3 in cancer

Individual and combined effect of TP53, MDM2, MDM4, MTHFR, CCR5, and CASP8 gene polymorphisms in lung cancer

Reduced QSOX1 enhances radioresistance in nasopharyngeal carcinoma

Greater low-density lipoprotein cholesterol variability is associated with increased progression to dialysis in patients with chronic kidney disease stage 3

Global view of a drug-sensitivity gene network

Ovatodiolide targets chronic myeloid leukemia stem cells by epigenetically upregulating hsa-miR-155, suppressing the BCR-ABL fusion gene and dysregulating the PI3K/AKT/mTOR pathway

Vitexin induces apoptosis by suppressing autophagy in multi-drug resistant colorectal cancer cells

BAFF and APRIL expression as an autoimmune signature of membranous nephropathy

Specific alterations in gut microbiota are associated with prognosis of Budd–Chiari syndrome

Preclinical study of a Kv11.1 potassium channel activator as antineoplastic approach for breast cancer

Enhanced anti-tumor efficacy and mechanisms associated with docetaxel-piperine combination- in vitro and in vivo investigation using a taxane-resistant prostate cancer model

Del17p does not always significantly influence the survival of B-cell chronic lymphoproliferative disorders

MAGE-A11 is activated through TFCP2/ZEB1 binding sites de-methylation as well as histone modification and facilitates ESCC tumor growth

Thiotepa-busulfan-fludarabine compared to busulfan-fludarabine for sibling and unrelated donor transplant in acute myeloid leukemia in first remission

Copy number profiles of paired primary and metastatic colorectal cancers

Hyperplastic thymus with increased angiogenesis is correlated with elevated serum thyroglobulin level in differentiated thyroid cancer patients with TENIS syndrome

Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia

Interleukin-34 sustains pro-tumorigenic signals in colon cancer tissue

MUC1 induces M2 type macrophage influx during postpartum mammary gland involution and triggers breast cancer

Brain- and brain tumor-penetrating disulfiram nanoparticles: Sequence of cytotoxic events and efficacy in human glioma cell lines and intracranial xenografts

Novel cooperative pathway of c-Myc and Furin, a pro-protein convertase, in cell proliferation as a therapeutic target in ovarian cancers

Chronic activation profile of circulating CD8+ T cells in Sézary syndrome

Drug-induced ciliogenesis in pancreatic cancer cells is facilitated by the secreted ATP-purinergic receptor signaling pathway

LncRNA Gas5 acts as a ceRNA to regulate PTEN expression by sponging miR-222-3p in papillary thyroid carcinoma

Melatonin attenuated brain death tissue extract-induced cardiac damage by suppressing DAMP signaling

Phosphatase of regenerating liver-3 is expressed in acute lymphoblastic leukemia and mediates leukemic cell adhesion, migration and drug resistance

Interferon β protects against avascular osteonecrosis through interleukin 6 inhibition and silent information regulator transcript-1 upregulation

Inhibition of tumor growth by cancer vaccine combined with metronomic chemotherapy and anti-PD-1 in a pre-clinical setting

FoxM1 and β-catenin predicts aggressiveness in Middle Eastern ovarian cancer and their co-targeting impairs the growth of ovarian cancer cells

Combined effects of PLK1 and RAS in hepatocellular carcinoma reveal rigosertib as promising novel therapeutic "dual-hit" option

Salinomycin inhibits cholangiocarcinoma growth by inhibition of autophagic flux

A spliced form of CD44 expresses the unique glycan that is recognized by the prostate cancer specific antibody F77

Epithelial-mesenchymal crosstalk induces radioresistance in HNSCC cells

Cognition, serum BDNF levels, and BDNF Val66Met polymorphism in type 2 diabetes patients and healthy controls

Inhibition of integrin β1-mediated oncogenic signalling by the antitumor microRNA-29 family in head and neck squamous cell carcinoma

Polymorphisms of long non-coding RNA HOTAIR with breast cancer susceptibility and clinical outcomes for a southeast Chinese Han population

Androgen receptor/let-7a signaling regulates breast tumor-initiating cells

Integrating the dysregulated inflammasome-based molecular functionome in the malignant transformation of endometriosis-associated ovarian carcinoma

Molecular mechanisms of calcium signaling in the modulation of small intestinal ion transports and bicarbonate secretion

Therapeutic effect of nerve growth factor on canine cerebral infarction evaluated by MRI

Downregulation of N⁶-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N⁶-methyladenosine levels

PM2.5 inhalation induces intracranial atherosclerosis which may be ameliorated by omega 3 fatty acids

Reduced recruitment of 53BP1 during interstrand crosslink repair is associated with genetically inherited attenuation of mitomycin C sensitivity in a family with Fanconi anemia

Betulinic acid impairs metastasis and reduces immunosuppressive cells in breast cancer models

Similarity and difference in tumor-infiltrating lymphocytes in original tumor tissues and those of in vitro expanded populations in head and neck cancer

The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth

MiR-27b directly targets Rab3D to inhibit the malignant phenotype in colorectal cancer

Design of miRNA sponges for MDV-1 as a therapeutic strategy against lymphomas

Identification of survivin as a promising target for the immunotherapy of adult B-cell acute lymphoblastic leukemia

Rs2459976 in ZW10 gene associated with congenital heart diseases in Chinese Han population

Efficacy of assessing circulating cell-free DNA using a simple fluorescence assay in patients with triple-negative breast cancer receiving neoadjuvant chemotherapy: a prospective observational study

Catalpol protects mice against Lipopolysaccharide/D-galactosamine-induced acute liver injury through inhibiting inflammatory and oxidative response

Nucleoside reverse transcriptase inhibitor-induced rat oocyte dysfunction and low fertility mediated by autophagy

Combination of a hypomethylating agent and inhibitors of PARP and HDAC traps PARP1 and DNMT1 to chromatin, acetylates DNA repair proteins, down-regulates NuRD and induces apoptosis in human leukemia and lymphoma cells

Differential regulation of the androgen receptor by protein phosphatase regulatory subunits

Decrease in PSCA expression caused by Helicobacter pylori infection may promote progression to severe gastritis

Validation of a hypoxia related gene signature in multiple soft tissue sarcoma cohorts

Primary breast diffuse large B-cell lymphoma: a population-based study from 1975 to 2014

Impact of STAT3 phosphorylation in glioblastoma stem cells radiosensitization and patient outcome

Investigation on outcomes and bacterial distributions of liver cirrhosis patients with gram-negative bacterial bloodstream infection

Proteomic profiling of antibody-inducing immunogens in tumor tissue identifies PSMA1, LAP3, ANXA3, and maspin as colon cancer markers

Up-regulation of hexokinase II contributes to rituximab-chemotherapy resistance and is a clinically relevant target for therapeutic development

Optimal time of tumour response evaluation and effectiveness of hypofractionated proton beam therapy for inoperable or recurrent hepatocellular carcinoma

Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells

Clinical outcomes and differential effects of PI3K pathway mutation in obese versus non-obese patients with cervical cancer

Transcriptome profiling identified differentially expressed genes and pathways associated with tamoxifen resistance in human breast cancer

The vascular disrupting agent combretastatin A-4 phosphate causes prolonged elevation of proteins involved in heme flux and function in resistant tumor cells

Pulmonary sarcomatoid carcinoma: University of Cincinnati experience

Cancer immunogenomic approach to neoantigen discovery in a checkpoint blockade responsive murine model of oral cavity squamous cell carcinoma

HLA class I loss and PD-L1 expression in lung cancer: impact on T-cell infiltration and immune escape

Potential for subsets of wt-NPM1 primary AML blasts to respond to retinoic acid treatment

Effect of NET-1 siRNA conjugated sub-micron bubble complex combined with low-frequency ultrasound exposure in gene transfection

Ophiopogonin B sensitizes TRAIL-induced apoptosis through activation of autophagy flux and downregulates cellular FLICE-like inhibitory protein

CKS1 expression in melanocytic nevi and melanoma

Germline polymorphism of interferon-lambda3 is clinically associated with progression of renal cell carcinoma

Association between CYP17 T-34C rs743572 and breast cancer risk

A plasma telomeric cell-free DNA level in unaffected women with BRCA1 or/and BRCA2 mutations: a pilot study

Oxidative stress promotes exit from the stem cell state and spontaneous neuronal differentiation

Meta-analysis of three genome-wide association studies identifies two loci that predict survival and treatment outcome in breast cancer

The prognostic value of p62 in solid tumor patients: a meta-analysis

Which type of congenital malformations is significantly increased in singleton pregnancies following after in vitro fertilization/intracytoplasmic sperm injection: a systematic review and meta-analysis