Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer

The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas

A small molecule inhibitor of PAI-1 protects against doxorubicin-induced cellular senescence

Baicalein protects against oxLDL-caused oxidative stress and inflammation by modulation of AMPK- alpha

Toll-like 4 receptor /NFκB inflammatory/miR-146a pathway contributes to the ART-correlated preterm birth outcome

RNA binding protein, tristetraprolin in a murine model of recurrent pregnancy loss

Wogonin prevents TLR4-NF-κB-medicated neuro-inflammation and improves retinal ganglion cells survival in retina after optic nerve crush

Umbilical cord-derived mesenchymal stem cells reversed the suppressive deficiency of T regulatory cells from peripheral blood of patients with multiple sclerosis in a co-culture – a preliminary study

A long noncoding RNA positively regulates CD56 in human natural killer cells

Generation of infectious RNA complexes in orbiviruses: RNA-RNA interactions of genomic segments

Janus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells

Tumor and circulating biomarkers in patients with second-line hepatocellular carcinoma from the randomized phase II study with tivantinib

Smac mimetic LCL161 supports neuroblastoma chemotherapy in a drug class-dependent manner and synergistically interacts with ALK inhibitor TAE684 in cells with ALK mutation F1174L

Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: predictive value of DNA-PK and phosphorylated ACC

IMP1, an mRNA binding protein that reduces the metastatic potential of breast cancer in a mouse model

Role of Dicer as a prognostic predictor for survival in cancer patients: a systematic review with a meta-analysis

Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality

Interaction of microtubules with the actin cytoskeleton via cross-talk of EB1-containing +TIPs and γ-actin in epithelial cells

Regulation of tumor growth by circulating full-length chromogranin A

Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia

MicroRNA-26b attenuates monocrotaline-induced pulmonary vascular remodeling via targeting connective tissue growth factor (CTGF) and cyclin D1 (CCND1)

Computational identification of microRNAs associated to both epithelial to mesenchymal transition and NGAL/MMP-9 pathways in bladder cancer

Aberrant expression of KPNA2 is associated with a poor prognosis and contributes to OCT4 nuclear transportation in bladder cancer

c-Abl inhibits breast cancer tumorigenesis through reactivation of p53-mediated p21 expression

DRG1 is a potential oncogene in lung adenocarcinoma and promotes tumor progression via spindle checkpoint signaling regulation

SASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer

Prognostic role and correlation of CA9, CD31, CD68 and CD20 with the desmoplastic stroma in pancreatic ductal adenocarcinoma

Long non-coding RNA CRNDE promotes gallbladder carcinoma carcinogenesis and as a scaffold of DMBT1 and C-IAP1 complexes to activating PI3K-AKT pathway

Aberrant expression of JNK-associated leucine-zipper protein, JLP, promotes accelerated growth of ovarian cancer

Comprehensive adipocytic and neurogenic tissue microarray analysis of NY-ESO-1 expression - a promising immunotherapy target in malignant peripheral nerve sheath tumor and liposarcoma

Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding

Synergistic activity of ALK and mTOR inhibitors for the treatment of NPM-ALK positive lymphoma

Prognostic role of the lymph node ratio in node positive colorectal cancer: a meta-analysis

Genomic characterization of liver metastases from colorectal cancer patients

Grp94 in complexes with IgG is a soluble diagnostic marker of gastrointestinal tumors and displays immune-stimulating activity on peripheral blood immune cells

Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway

PD-1 mediates functional exhaustion of activated NK cells in patients with Kaposi sarcoma

Multi-cycle chemotherapy with the glycolipid-like polymeric micelles evade cancer stem cell enrichment in breast cancer therapy

Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway

Elevated level of Interleukin-35 in colorectal cancer induces conversion of T cells into iTr35 by activating STAT1/STAT3

Targeting cancer initiating cells by promoting cell differentiation and restoring chemosensitivity via dual inactivation of STAT3 and Src activity using an active component of Antrodia cinnamomea mycelia

Overcoming adaptive resistance in mucoepidermoid carcinoma through inhibition of the IKK-β/IκBα/NFκB axis

Tumour suppressor gene (CDKNA2) status on chromosome 9p in resected renal tissue improves prognosis of localised kidney cancer

The C-terminal domain of connexin43 modulates cartilage structure via chondrocyte phenotypic changes

The efficacy and safety of anti-PD-1/PD-L1 antibodies for treatment of advanced or refractory cancers: a meta-analysis

Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways

The role of SH3GL3 in myeloma cell migration/invasion, stemness and chemo-resistance

A novel co-drug of aspirin and ursolic acid interrupts adhesion, invasion and migration of cancer cells to vascular endothelium via regulating EMT and EGFR-mediated signaling pathways: multiple targets for cancer metastasis prevention and treatment

Intraglomerular crosstalk elaborately regulates podocyte injury and repair in diabetic patients: insights from a 3D multiscale modeling study

Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response

Cyr61-positive cancer stem-like cells enhances distal metastases of pancreatic cancer

Expression of the TPα and TPβ isoforms of the thromboxane prostanoid receptor (TP) in prostate cancer: clinical significance and diagnostic potential

MiR-128 reverses the gefitinib resistance of the lung cancer stem cells by inhibiting the c-met/PI3K/AKT pathway

Case-specific potentiation of glioblastoma drugs by pterostilbene

ADH1B and CDH1 polymorphisms predict prognosis in male patients with non-metastatic laryngeal cancer

Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation

Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells

An artificial lncRNA targeting multiple miRNAs overcomes sorafenib resistance in hepatocellular carcinoma cells

Low carbohydrate diet prevents Mcl-1-mediated resistance to BH3-mimetics

Thermo-sensitive composite hydrogels based on poloxamer 407 and alginate and their therapeutic effect in embolization in rabbit VX2 liver tumors

Co-application of canavanine and irradiation uncouples anticancer potential of arginine deprivation from citrulline availability

Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis

p53 in the mitochondria, as a trans-acting protein, provides error-correction activities during the incorporation of non-canonical dUTP into DNA

ERBB2 mutations associated with solid variant of high-grade invasive lobular breast carcinomas

Promoter methylation patterns of ABCB1, ABCC1 and ABCG2 in human cancer cell lines, multidrug-resistant cell models and tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients

CARP-1 functional mimetics are novel inhibitors of drug-resistant triple negative breast cancers

LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors

Asporin enhances colorectal cancer metastasis through activating the EGFR/Src/cortactin signaling pathway

Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells

Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice

Low-dose salinomycin induces anti-leukemic responses in AML and MLL

GPR30 disrupts the balance of GABAergic and glutamatergic transmission in the spinal cord driving to the development of bone cancer pain

Recombinant human bone morphogenetic protein-2 inhibits gastric cancer cell proliferation by inactivating Wnt signaling pathway via c-Myc with aurora kinases

Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer

Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells

Integrating microRNA and mRNA expression profiles of acute promyelocytic leukemia cells to explore the occurrence mechanisms of differentiation syndrome

Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation

Identification of long non-coding RNAs biomarkers for early diagnosis of myocardial infarction from the dysregulated coding-non-coding co-expression network

Matrix metalloproteinase-13 refines pathological staging of precancerous colorectal lesions

CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma

Flavan-3-ols consumption and cancer risk: a meta-analysis of epidemiologic studies

NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction

Chicken GHR natural antisense transcript regulates GHR mRNA in LMH cells

Anti-EGFR monoclonal antibodies and EGFR tyrosine kinase inhibitors as combination therapy for triple-negative breast cancer

Decreased expression of IDH1-R132H correlates with poor survival in gastrointestinal cancer

Locked nucleic acid-inhibitor of miR-205 decreases endometrial cancer cells proliferation in vitro and in vivo

Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma

Asn-Gly-Arg-modified polydopamine-coated nanoparticles for dual-targeting therapy of brain glioma in rats

Second-generation proteasome inhibitor carfilzomib enhances doxorubicin-induced cytotoxicity and apoptosis in breast cancer cells

Lipopolysaccharide increases the release of VEGF-C that enhances cell motility and promotes lymphangiogenesis and lymphatic metastasis through the TLR4- NF-κB/JNK pathways in colorectal cancer

Role of BCL9L in transforming growth factor-β (TGF-β)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer

The other face of miR-17-92a cluster, exhibiting tumor suppressor effects in prostate cancer

Bone morphogenetic protein-9 is a potent growth inhibitor of hepatocellular carcinoma and reduces the liver cancer stem cells population

Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

TERT rs2853676 polymorphisms correlate with glioma prognosis in Chinese population

A dosimetric and treatment efficiency evaluation of stereotactic body radiation therapy for peripheral lung cancer using flattening filter free beams

Epithelial splicing regulatory protein 1 and 2 paralogues correlate with splice signatures and favorable outcome in human colorectal cancer

SHP2 phosphatase as a novel therapeutic target for melanoma treatment

Tetraspecific scFv construct provides NK cell mediated ADCC and self-sustaining stimuli via insertion of IL-15 as a cross-linker

CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network

Novel lymph node ratio predicts prognosis of colorectal cancer patients after radical surgery when tumor deposits are counted as positive lymph nodes: a retrospective multicenter study

Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients

miR-28-5p acts as a tumor suppressor in renal cell carcinoma for multiple antitumor effects by targeting RAP1B

The impact of neuronal Notch-1/JNK pathway on intracerebral hemorrhage-induced neuronal injury of rat model

Antibody-based PET of uPA/uPAR signaling with broad applicability for cancer imaging

Transfer of functional microRNAs between glioblastoma and microvascular endothelial cells through gap junctions

A PRISMA-compliant meta-analysis of MDM4 genetic variants and cancer susceptibility

A comprehensive meta-analysis of genetic associations between five key SNPs and colorectal cancer risk

The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells

Identification of a five B cell-associated gene prognostic and predictive signature for advanced glioma patients harboring immunosuppressive subtype preference

Circulating vascular endothelial growth factor (VEGF) as predictive factor of progression-free survival in patients with advanced chordoma receiving sorafenib: an analysis from a phase II trial of the french sarcoma group (GSF/GETO)

Generation of affibody molecules specific for HPV16 E7 recognition

Cystic brain metastasis is associated with poor prognosis in patients with advanced breast cancer

FGF4 induces epithelial-mesenchymal transition by inducing store-operated calcium entry in lung adenocarcinoma

Classifying lower grade glioma cases according to whole genome gene expression

Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis

MicroRNA-98 acts as a tumor suppressor in hepatocellular carcinoma via targeting SALL4

Axillary and internal mammary sentinel lymph node biopsy in breast cancer after neoadjuvant chemotherapy

Variable but consistent pattern of Meningioma 1 gene (MN1) expression in different genetic subsets of acute myelogenous leukaemia and its potential use as a marker for minimal residual disease detection

Somatic alterations of targetable oncogenes are frequently observed in BRCA1/2 mutation negative male breast cancers

Immune adjuvant effect of a Toxoplasma gondii profilin-like protein in autologous whole-tumor-cell vaccination in mice

Exploring timing activation of functional pathway based on differential co-expression analysis in preimplantation embryogenesis

Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2α-ATF4-xCT pathway

Cytomorphological characteristics of glassy cell carcinoma of the uterine cervix: histopathological correlation and human papillomavirus genotyping

Advanced lung adenocarcinomas with ROS1-rearrangement frequently show hepatoid cell

Engineering of double recombinant vaccinia virus with enhanced oncolytic potential for solid tumor virotherapy

Prostate-specific membrane antigen (PSMA) assembles a macromolecular complex regulating growth and survival of prostate cancer cells “in vitro” and correlating with progression “in vivo”

Low pH impairs complement-dependent cytotoxicity against IgG-coated target cells

MicroRNA-126 affects rheumatoid arthritis synovial fibroblast proliferation and apoptosis by targeting PIK3R2 and regulating PI3K-AKT signal pathway

Germline mutations in Japanese familial pancreatic cancer patients

Overexpression and potential roles of NRIP1 in psoriasis

Endotoxin promotes neutrophil hierarchical chemotaxis via the p38-membrane receptor pathway

A next-generation bifunctional photosensitizer with improved water-solubility for photodynamic therapy and diagnosis

Proteomic identification of the lactate dehydrogenase A in a radioresistant prostate cancer xenograft mouse model for improving radiotherapy

Role of transarterial chemoembolization in relation with sorafenib for patients with advanced hepatocellular carcinoma

Preoperative neutrophil-to-lymphocyte ratio and tumor-related factors to predict lymph node metastasis in patients with pancreatic ductal adenocarcinoma (PDAC)

LncRNAs act as prognostic and diagnostic biomarkers in renal cell carcinoma: a systematic review and meta-analysis

Lymph node ratio-based staging system as an alternative to the current TNM staging system to assess outcome in adenocarcinoma of the esophagogastric junction after surgical resection

Prognostic and predictive value of EGFR in head and neck squamous cell carcinoma

Discovery and clinical introduction of first-in-class imipridone ONC201

ISG15 in the tumorigenesis and treatment of cancer: An emerging role in malignancies of the digestive system