RNA methyltransferase NSUN2 promotes stress-induced HUVEC senescence

Dopamine D₂ gene expression interacts with environmental enrichment to impact lifespan and behavior

Safety of two-year caloric restriction in non-obese healthy individuals

BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse

MicroRNA signatures in vitreous humour and plasma of patients with exudative AMD

Towards understanding the lifespan extension by reduced insulin signaling: bioinformatics analysis of DAF-16/FOXO direct targets in Caenorhabditis elegans

Olfactory phenotypic expression unveils human aging

Curcumin elevates sirtuin level but does not postpone in vitro senescence of human cells building the vasculature

Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium

Methylomic predictors demonstrate the role of NF-κB in old-age mortality and are unrelated to the aging-associated epigenetic drift

Reduced serpinB9-mediated caspase-1 inhibition can contribute to autoinflammatory disease

Nrf2 plays a pivotal role in protection against burn trauma-induced intestinal injury and death

Ascophyllan functions as an adjuvant to promote anti-cancer effect by dendritic cell activation

B1a cells play a pathogenic role in the development of autoimmune arthritis

5-Fluorouracil targets thymidylate synthase in the selective suppression of T_H17 cell differentiation

Capsules of virulent pneumococcal serotypes enhance formation of neutrophil extracellular traps during in vivo pathogenesis of pneumonia

Development of interleukin-17-producing Vγ2⁺ γδ T cells is reduced by ICOS signaling in the thymus

Distinctly altered gut microbiota in the progression of liver disease

C3 deficiency ameliorates the negative effects of irradiation of the young brain on hippocampal development and learning

The cytoskeletal arrangements necessary to neurogenesis

Amyloid precursor protein and amyloid precursor-like protein 2 in cancer

Bile acid-FXRα pathways regulate male sexual maturation in mice

Interplay between PCBP2 and miRNA modulates ARHGDIA expression and function in glioma migration and invasion

TGF-β1 and TGF-β2 abundance in liver diseases of mice and men

Tumor suppressor role of microRNA-1296 in triple-negative breast cancer

miR-340 predicts glioblastoma survival and modulates key cancer hallmarks through down-regulation of NRAS

Macrophage targeting contributes to the inhibitory effects of embelin on colitis-associated cancer

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression

Use of genetically encoded, light-gated ion translocators to control tumorigenesis

Serum high expression of miR-214 and miR-135b as novel predictor for myeloma bone disease development and prognosis

MicroRNA expression profiles of drug-resistance breast cancer cells and their exosomes

Molecular characterization of colorectal cancer patients and concomitant patient-derived tumor cell establishment

The afatinib resistance of in vivo generated H1975 lung cancer cell clones is mediated by SRC/ERBB3/c-KIT/c-MET compensatory survival signaling

Ezrin contributes to cervical cancer progression through induction of epithelial-mesenchymal transition

Impact of age on efficacy of postoperative oxaliplatin-based chemotherapy in patients with rectal cancer after neoadjuvant chemoradiotherapy

Parotid area lymph node metastases from preliminarily diagnosed patients with nasopharyngeal carcinoma: report on tumor characteristics and oncologic outcomes

MicroRNA-27b up-regulated by human papillomavirus 16 E7 promotes proliferation and suppresses apoptosis by targeting polo-like kinase2 in cervical cancer

High expression of Zinc-finger protein X-linked promotes tumor growth and predicts a poor outcome for stage II/III colorectal cancer patients

Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors

Oncogenic epithelial cell-derived exosomes containing Rac1 and PAK2 induce angiogenesis in recipient endothelial cells

Downregulation of miR-137 and miR-6500-3p promotes cell proliferation in pediatric high-grade gliomas

PD-L1 expression as predictive biomarker in patients with NSCLC: a pooled analysis

Fibroblast growth factor receptor 2 expression, but not its genetic amplification, is associated with tumor growth and worse survival in esophagogastric junction adenocarcinoma

Multiparametric monitoring of chemotherapy treatment response in locally advanced breast cancer using quantitative ultrasound and diffuse optical spectroscopy

Predictive role of microRNA-related genetic polymorphisms in the pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients

DDA1 promotes stage IIB–IIC colon cancer progression by activating NFκB/CSN2/GSK-3β signaling

Decreased level of RASSF6 in sporadic colorectal cancer and its anti-tumor effects both in vitro and in vivo

Early-phase circulating miRNAs predict tumor recurrence and survival of hepatocellular carcinoma patients after liver transplantation

Impact of molecular profiling on overall survival of patients with advanced ovarian cancer

Environmental exposure and HPV infection may act synergistically to induce lung tumorigenesis in nonsmokers

Prognostic role of STAT3 in solid tumors: a systematic review and meta-analysis

A BRCA1 deficient, NFκB driven immune signal predicts good outcome in triple negative breast cancer

ZSTK474, a specific class I phosphatidylinositol 3-kinase inhibitor, induces G1 arrest and autophagy in human breast cancer MCF-7 cells

Tumor-selective mitochondrial network collapse induced by atmospheric gas plasma-activated medium

Genetic variants of lncRNA HOTAIR contribute to the risk of osteosarcoma

Vascular patterns provide therapeutic targets in aggressive neuroblastic tumors

High-throughput drug library screening identifies colchicine as a thyroid cancer inhibitor

Knockdown of long non-coding RNA TP73-AS1 inhibits cell proliferation and induces apoptosis in esophageal squamous cell carcinoma

Expression profile and prognostic value of NNMT in patients with pancreatic cancer

Carnitine palmitoyl transferase-1A (CPT1A): a new tumor specific target in human breast cancer

Fibroblast-induced switching to the mesenchymal-like phenotype and PI3K/mTOR signaling protects melanoma cells from BRAF inhibitors

Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas

Somatostatin receptor expression in small cell lung cancer as a prognostic marker and a target for peptide receptor radionuclide therapy

MicroRNA-432 functions as a tumor suppressor gene through targeting E2F3 and AXL in lung adenocarcinoma

Anti-apoptotic ARC protein confers chemoresistance by controlling leukemia-microenvironment interactions through a NFκB/IL1β signaling network

MicroRNA deregulation in triple negative breast cancer reveals a role of miR-498 in regulating BRCA1 expression

Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells

Optimized selection of three major EGFR-TKIs in advanced EGFR-positive non-small cell lung cancer: a network meta-analysis

Biomarkers of evasive resistance predict disease progression in cancer patients treated with antiangiogenic therapies

Prostate stromal cell proteomics analysis discriminates normal from tumour reactive stromal phenotypes

Survival kinase genes present prognostic significance in glioblastoma

Insulin receptor substrate 1 is a substrate of the Pim protein kinases

Folic-acid metabolism and DNA-repair phenotypes differ between neuroendocrine lung tumors and associate with aggressive subtypes, therapy resistance and outcome

Suppression of miR-204 enables oral squamous cell carcinomas to promote cancer stemness, EMT traits, and lymph node metastasis

Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway

MicroRNA-92b represses invasion-metastasis cascade of esophageal squamous cell carcinoma

Adipocytes WNT5a mediated dedifferentiation: a possible target in pancreatic cancer microenvironment

Protein arginine methyltransferase 1 may be involved in pregnane x receptor-activated overexpression of multidrug resistance 1 gene during acquired multidrug resistant

Icmt inhibition exerts anti-angiogenic and anti-hyperpermeability activities impeding malignant pleural effusion

Reactivation of epigenetically silenced miR-124 reverses the epithelial-to-mesenchymal transition and inhibits invasion in endometrial cancer cells via the direct repression of IQGAP1 expression

Prevention of irradiation-induced salivary hypofunction by rapamycin in swine parotid glands

Repeated observation of immune gene sets enrichment in women with non-small cell lung cancer

The effects of curcumin (diferuloylmethane) on body composition of patients with advanced pancreatic cancer

ZCWPW1 is associated with late-onset Alzheimer's disease in Han Chinese: a replication study and meta-analyses

Exogenous hepatitis B virus envelope proteins induce endoplasmic reticulum stress: involvement of cannabinoid axis in liver cancer cells

miR-155 regulates the proliferation and invasion of clear cell renal cell carcinoma cells by targeting E2F2

Everolimus exhibits anti-tumorigenic activity in obesity-induced ovarian cancer

The association of six polymorphisms of five genes involved in three steps of nucleotide excision repair pathways with hepatocellular cancer risk

Antitumor effects of calgranulin B internalized in human colon cancer cells

MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer

CWP232228 targets liver cancer stem cells through Wnt/β‑catenin signaling: a novel therapeutic approach for liver cancer treatment

Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion

Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer

Glutamate dependent NMDA receptor 2D is a novel angiogenic tumour endothelial marker in colorectal cancer

The antinociceptive effects of ferulic acid on neuropathic pain: involvement of descending monoaminergic system and opioid receptors

Overexpression of pig selenoprotein S blocks OTA-induced promotion of PCV2 replication by inhibiting oxidative stress and p38 phosphorylation in PK15 cells

Metabolomics profiling in plasma samples from glioma patients correlates with tumor phenotypes

Nomograms to estimate long-term overall survival and breast cancer-specific survival of patients with luminal breast cancer

The effect of HMGB1 on the clinicopathological and prognostic features of non-small cell lung cancer

Immunoglobulin gene rearrangements in Chinese and Italian patients with chronic lymphocytic leukemia

Multitargeting activity of miR-24 inhibits long-term melatonin anticancer effects

Lnc-SGK1 induced by Helicobacter pylori infection and highsalt diet promote Th2 and Th17 differentiation in human gastric cancer by SGK1/Jun B signaling

RalA, a GTPase targeted by miR‑181a, promotes transformation and progression by activating the Ras‑related signaling pathway in chronic myelogenous leukemia

The clock gene PER1 suppresses expression of tumor-related genes in human oral squamous cell carcinoma

Long non-coding RNAs as prognostic markers in human breast cancer

MEK1 signaling promotes self-renewal and tumorigenicity of liver cancer stem cells via maintaining SIRT1 protein stabilization

Pre-treatment evaluation of 5-fluorouracil degradation rate: association of poor and ultra-rapid metabolism with severe toxicity in a colorectal cancer patients cohort

Loss of SOCS3 in myeloid cells prolongs survival in a syngeneic model of glioma

Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis

Dephosphorylation and mitochondrial translocation of cofilin sensitizes human leukemia cells to cerulenin-induced apoptosis via the ROCK1/Akt/JNK signaling pathway

Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent

The efficacy and toxicity of individualized intensity‑modulated radiotherapy based on the tumor extension patterns of nasopharyngeal carcinoma

Repeated PM2.5 exposure inhibits BEAS-2B cell P53 expression through ROS-Akt-DNMT3B pathway-mediated promoter hypermethylation

The long non-coding RNA EPB41L4A-AS2 inhibits tumor proliferation and is associated with favorable prognoses in breast cancer and other solid tumors

Inhibition of estrogen biosynthesis enhances lymphoma growth in mice

MicroRNA-137 inhibits tumor growth and sensitizes chemosensitivity to paclitaxel and cisplatin in lung cancer

The preclinical study of predicting radiosensitivity in human nasopharyngeal carcinoma xenografts by 18F-ML-10 animal- PET/CT imaging

Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors

Whole transcriptome profiling of patient-derived xenograft models as a tool to identify both tumor and stromal specific biomarkers

Radiation therapy generates platelet-activating factor agonists

EphA8 is a prognostic marker for epithelial ovarian cancer

Quantification of mutant alleles in circulating tumor DNA can predict survival in lung cancer

Reciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2

Positive feedback regulation between IL10 and EGFR promotes lung cancer formation

The Bif-1-Dynamin 2 membrane fission machinery regulates Atg9-containing vesicle generation at the Rab11-positive reservoirs

Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers

The synergic antitumor effects of paclitaxel and temozolomide co-loaded in mPEG-PLGA nanoparticles on glioblastoma cells

Protective role of p53 in skin cancer: Carcinogenesis studies in mice lacking epidermal p53

Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival

Activation of mesenchymal stem cells by macrophages promotes tumor progression through immune suppressive effects

Tenascin-C serum levels and its prognostic power in non-small cell lung cancer

Inhibition of miR301 enhances Akt-mediated cell proliferation by accumulation of PTEN in nucleus and its effects on cell-cycle regulatory proteins

ERα propelled aberrant global DNA hypermethylation by activating the DNMT1 gene to enhance anticancer drug resistance in human breast cancer cells

MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors

Transcription factor RUNX2 up-regulates chemokine receptor CXCR4 to promote invasive and metastatic potentials of human gastric cancer

Development of a new outcome prediction model for Chinese patients with penile squamous cell carcinoma based on preoperative serum C-reactive protein, body mass index, and standard pathological risk factors: the TNCB score group system

Longterm effects of palliative local treatment of incurable metastatic lesions in colorectal cancer patients

Development and validation of a prognostic nomogram based on the log odds of positive lymph nodes (LODDS) for breast cancer

Development and validation of a surgical-pathologic staging and scoring system for cervical cancer