Oncotarget
E2f1 and E2f3 inhibit tumorigenesis on a retinoblastoma-sensitized background. See Benavente et al.
Targeting IL-17 for pancreatic cancer prevention |
https://doi.org/10.18632/oncotarget.2618 Florencia McAllister, and Steven D. Leach |
9530-9531 |
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Rethinking glioma treatment strategy |
https://doi.org/10.18632/oncotarget.2619 Tatsuya Ozawa, and Eric C. Holland |
9532-9533 |
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How mRNA is misspliced in acute myelogenous leukemia (AML)? |
https://doi.org/10.18632/oncotarget.2304 Aminetou Mint Mohamed, Morgan Thénoz, Françoise Solly, Marie Balsat, Franck Mortreux, and Eric Wattel |
9534-9545 |
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AXL kinase as a novel target for cancer therapy |
https://doi.org/10.18632/oncotarget.2542 Xiaoliang Wu, Xuewen Liu, Sanjay Koul, Chang Youl Lee, Zhenfeng Zhang, and Balazs Halmos |
9546-9563 |
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Inhibition of STAT5: A therapeutic option in BCR-ABL1-driven leukemia |
https://doi.org/10.18632/oncotarget.2465 Angelika Berger, Veronika Sexl, Peter Valent, and Richard Moriggl |
9564-9576 |
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The nuclear import of ribosomal proteins is regulated by mTOR |
https://doi.org/10.18632/oncotarget.2473 Dubek Kazyken, Yelimbek Kaz, Vladimir Kiyan, Assylbek A. Zhylkibayev, Chien-Hung Chen, Nitin K. Agarwal, and Dos D. Sarbassov |
9577-9593 |
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Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression |
https://doi.org/10.18632/oncotarget.2468 Claudia A. Benavente, David Finkelstein, Dianna A. Johnson, Jean-Christophe Marine, Ruth Ashery-Padan, and Michael A. Dyer |
9594-9608 |
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Melanoma patient-derived xenografts accurately model the disease and develop fast enough to guide treatment decisions |
https://doi.org/10.18632/oncotarget.2445 Berglind O. Einarsdottir, Roger Olofsson Bagge, Joydeep Bhadury, Henrik Jespersen, Jan Mattsson, Lisa M. Nilsson, Katarina Truvé, Marcela Dávila López, Peter Naredi, Ola Nilsson, Ulrika Stierner, Lars Ny, and Jonas A. Nilsson |
9609-9618 |
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The Hippo transducer TAZ as a biomarker of pathological complete response in HER2-positive breast cancer patients treated with trastuzumab-based neoadjuvant therapy |
https://doi.org/10.18632/oncotarget.2449 Patrizia Vici, Marcella Mottolese, Laura Pizzuti, Maddalena Barba, Francesca Sperati, Irene Terrenato, Anna Di Benedetto, Clara Natoli, Teresa Gamucci, Domenico Angelucci, Maria Teresa Ramieri, Luigi Di Lauro, Domenico Sergi, Monica Bartucci, Rosanna Dattilo, Alfredo Pagliuca, Ruggero De Maria, and Marcello Maugeri-Saccà |
9619-9625 |
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Heterotrimeric G-protein alpha-12 (Gα12) subunit promotes oral cancer metastasis |
https://doi.org/10.18632/oncotarget.2437 Chai Phei Gan, Vyomesh Patel, Constantinos M. Mikelis, Rosnah binti Zain, Alfredo A. Molinolo, Mannil Thomas Abraham, Soo-Hwang Teo, Zainal Ariff Abdul Rahman, J. Silvio Gutkind, and Sok Ching Cheong |
9626-9640 |
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Chemoradiation provides a physiological selective pressure that increases the expansion of aberrant TP53 tumor variants in residual rectal cancerous regions |
https://doi.org/10.18632/oncotarget.2438 Kazuko Sakai, Shinsuke Kazama, Yuzo Nagai, Koji Murono, Toshiaki Tanaka, Soichiro Ishihara, Eiji Sunami, Shuta Tomida, Kazuto Nishio, and Toshiaki Watanabe |
9641-9649 |
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Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients |
https://doi.org/10.18632/oncotarget.2520 Corinna Eichelser, Isabel Stückrath, Volkmar Müller, Karin Milde-Langosch, Harriet Wikman, Klaus Pantel, and Heidi Schwarzenbach |
9650-9663 |
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Tumor hypoxia enhances Non-Small Cell Lung Cancer metastasis by selectively promoting macrophage M2 polarization through the activation of ERK signaling |
https://doi.org/10.18632/oncotarget.1856 Jun Zhang, Ji Cao, Shenglin Ma, Rong Dong, Wen Meng, Meidan Ying, Qinjie Weng, Zibo Chen, Jian Ma, Qingxia Fang, Qiaojun He, and Bo Yang |
9664-9677 |
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Expression of stemness genes in primary breast cancer tissues: the role of SOX2 as a prognostic marker for detection of early recurrence |
https://doi.org/10.18632/oncotarget.1936 Mauro Finicelli, Giovanni Benedetti, Tiziana Squillaro, Barbara Pistilli, Andrea Marcellusi, Paola Mariani, Alfredo Santinelli, Luciano Latini, Umberto Galderisi, and Antonio Giordano |
9678-9688 |
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Involvement of FoxQ1 in NSCLC through regulating EMT and increasing chemosensitivity |
https://doi.org/10.18632/oncotarget.2103 Jian Feng, Liqin Xu, Songshi Ni, Jun Gu, Huijun Zhu, Haiying Wang, Shu Zhang, Wei Zhang, and Jianfei Huang |
9689-9702 |
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SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma |
https://doi.org/10.18632/oncotarget.2232 Jeffrey Wojton, Walter Hans Meisen, Naduparambil K. Jacob, Amy Haseley Thorne, Jayson Hardcastle, Nicholas Denton, Zhengtao Chu, Nina Dmitrieva, Rachel Marsh, Erwin G. Van Meir, Chang-Hyuk Kwon, Arnab Chakravarti, Xiaoyang Qi, and Balveen Kaur |
9703-9709 |
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Diacylglycerol kinase α promotes 3D cancer cell growth and limits drug sensitivity through functional interaction with Src |
https://doi.org/10.18632/oncotarget.2344 Pedro Torres-Ayuso, Manuel Daza-Martín, Jorge Martín-Pérez, Antonia Ávila-Flores, and Isabel Mérida |
9710-9726 |
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Cancer-derived immunoglobulin G promotes LPS-induced proinflammatory cytokine production via binding to TLR4 in cervical cancer cells |
https://doi.org/10.18632/oncotarget.2359 Juping Wang, Danyi Lin, Hui Peng, Jimin Shao, and Jiang Gu |
9727-9743 |
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Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth |
https://doi.org/10.18632/oncotarget.2403 Juan Huertas-Martínez, Santiago Rello-Varona, David Herrero-Martín, Ignasi Barrau, Silvia García-Monclús, Miguel Sáinz-Jaspeado, Laura Lagares-Tena, Yaiza Núñez-Álvarez, Silvia Mateo-Lozano, Jaume Mora, Josep Roma, Nuria Toran, Sebastian Moran, Roser López-Alemany, Soledad Gallego, Manel Esteller, Miguel A. Peinado, Xavier García del Muro, and Oscar M. Tirado |
9744-9755 |
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Amifostine alleviates radiation-induced lethal small bowel damage via promotion of 14-3-3σ-mediated nuclear p53 accumulation |
https://doi.org/10.18632/oncotarget.2386 Eng-Yen Huang, Feng-Sheng Wang, Yu-Min Chen, Yi-Fan Chen, Chung-Chi Wang, I-Hui Lin, Yu-Jie Huang, and Kuender D. Yang |
9756-9769 |
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Methylation of miR-155-3p in mantle cell lymphoma and other non-Hodgkin’s lymphomas |
https://doi.org/10.18632/oncotarget.2390 Rita Lh Yim, Kwan Yeung Wong, Yok Lam Kwong, Florence Loong, Chung Ying Leung, Raymond Chu, William W. Lam, Pak Kwan Hui, Raymond Lai, and Chor Sang Chin |
9770-9782 |
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Systematic dissection of the mechanisms underlying progesterone receptor downregulation in endometrial cancer |
https://doi.org/10.18632/oncotarget.2392 Shujie Yang, Yichen Jia, Xiaoyue Liu, Christopher Winters, Xinjun Wang, Yuping Zhang, Eric J. Devor, Adriann M. Hovey, Henry D. Reyes, Xue Xiao, Yang Xu, Donghai Dai, Xiangbing Meng, Kristina W. Thiel, Frederick E. Domann, and Kimberly K. Leslie |
9783-9797 |
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Hypermethylation of DAPK1 is an independent prognostic factor predicting survival in diffuse large B-cell lymphoma |
https://doi.org/10.18632/oncotarget.2394 Lasse Sommer Kristensen, Fazila Asmar, Konstantinos Dimopoulos, Mette Kathrine Nygaard, Derya Aslan, Jakob Werner Hansen, Elisabeth Ralfkiaer, and Kirsten Grønbæk |
9798-9810 |
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Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma |
https://doi.org/10.18632/oncotarget.2443 Amy Barone, Rajarshi Sengupta, Nicole M. Warrington, Erin Smith, Patrick Y. Wen, Rolf A. Brekken, Barbara Romagnoli, Garry Douglas, Eric Chevalier, Michael P. Bauer, Klaus Dembowsky, David Piwnica-Worms, and Joshua B. Rubin |
9811-9822 |
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TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1 |
https://doi.org/10.18632/oncotarget.2450 Soo-Im Choi, Seo-Yeon Kim, Jaeha Lee, Eun-Wie Cho, and In-Gyu Kim |
9823-9837 |
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A novel action mechanism for MPT0G013, a derivative of arylsulfonamide, inhibits tumor angiogenesis through up-regulation of TIMP3 expression |
https://doi.org/10.18632/oncotarget.2451 Chih-Ya Wang, Jing-Ping Liou, An-Chi Tsai, Mei-Jung Lai, Yi-Min Liu, Hsueh-Yun Lee, Jing-Chi Wang, Shiow-Lin Pan, and Che-Ming Teng |
9838-9850 |
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Prevention of diabetes-promoted colorectal cancer by (n-3) polyunsaturated fatty acids and (n-3) PUFA mimetic |
https://doi.org/10.18632/oncotarget.2453 Anna Algamas-Dimantov, Einav Yehuda-Shnaidman, Rachel Hertz, Irena Peri, Jacob Bar-Tana, and Betty Schwartz |
9851-9863 |
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Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes |
https://doi.org/10.18632/oncotarget.2454 Xiaoping Su, Gabriel G. Malouf, Yunxin Chen, Jianping Zhang, Hui Yao, Vicente Valero, John N. Weinstein, Jean-Philippe Spano, Funda Meric-Bernstam, David Khayat, and Francisco J. Esteva |
9864-9876 |
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Inhibition of SphK1 reduces radiation-induced migration and enhances sensitivity to cetuximab treatment by affecting the EGFR / SphK1 crosstalk |
https://doi.org/10.18632/oncotarget.2436 Carlotta Schiefler, Guido Piontek, Johannes Doescher, Dominik Schuettler, Martin Mißlbeck, Martina Rudelius, Anna Haug, Rudolf Reiter, Gero Brockhoff, and Anja Pickhard |
9877-9888 |
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Targeting the DNA replication checkpoint by pharmacologic inhibition of Chk1 kinase: a strategy to sensitize APC mutant colon cancer cells to 5-fluorouracil chemotherapy |
https://doi.org/10.18632/oncotarget.2475 Estefania Martino-Echarri, Beric R. Henderson, and Mariana G. Brocardo |
9889-9900 |
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RNA sequencing identifies specific PIWI-interacting small non-coding RNA expression patterns in breast cancer |
https://doi.org/10.18632/oncotarget.2476 Adnan Hashim, Francesca Rizzo, Giovanna Marchese, Maria Ravo, Roberta Tarallo, Giovanni Nassa, Giorgio Giurato, Gianluca Santamaria, Angela Cordella, Concita Cantarella, and Alessandro Weisz |
9901-9910 |
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Targeting L1 cell adhesion molecule expression using liposome-encapsulated siRNA suppresses prostate cancer bone metastasis and growth |
https://doi.org/10.18632/oncotarget.2478 Shian-Ying Sung, I-Hui Wu, Pei-Hsin Chuang, John A. Petros, Hsi-Chin Wu, Hong-Jie Zeng, Wei-Chien Huang, Leland W. K. Chung, and Chia-Ling Hsieh |
9911-9929 |
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Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML |
https://doi.org/10.18632/oncotarget.2479 Lyubov Zaitseva, Megan Y. Murray, Manar S. Shafat, Matthew J. Lawes, David J. MacEwan, Kristian M. Bowles, and Stuart A. Rushworth |
9930-9938 |
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Characterization of single disseminated prostate cancer cells reveals tumor cell heterogeneity and identifies dormancy associated pathways |
https://doi.org/10.18632/oncotarget.2480 Lisly Chéry, Hung-Ming Lam, Ilsa Coleman, Bryce Lakely, Roger Coleman, Sandy Larson, Julio A. Aguirre-Ghiso, Jing Xia, Roman Gulati, Peter S. Nelson, Bruce Montgomery, Paul Lange, Linda A. Snyder, Robert L. Vessella, and Colm Morrissey |
9939-9951 |
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Mutational profiles in triple-negative breast cancer defined by ultradeep multigene sequencing show high rates of PI3K pathway alterations and clinically relevant entity subgroup specific differences |
https://doi.org/10.18632/oncotarget.2481 Mark Kriegsmann, Volker Endris, Thomas Wolf, Nicole Pfarr, Albrecht Stenzinger, Sibylle Loibl, Carsten Denkert, Andreas Schneeweiss, Jan Budczies, Peter Sinn, and Wilko Weichert |
9952-9965 |
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Glipizide, an antidiabetic drug, suppresses tumor growth and metastasis by inhibiting angiogenesis |
https://doi.org/10.18632/oncotarget.2483 Cuiling Qi, Qin Zhou, Bin Li, Yang Yang, Liu Cao, Yuxiang Ye, Jiangchao Li, Yi Ding, Huiping Wang, Jintao Wang, Xiaodong He, Qianqian Zhang, Tian Lan, Kenneth Ka Ho Lee, Weidong Li, Xiaoyu Song, Jia Zhou, Xuesong Yang, and Lijing Wang |
9966-9979 |
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HSP90 inhibition downregulates thymidylate synthase and sensitizes colorectal cancer cell lines to the effect of 5FU-based chemotherapy |
https://doi.org/10.18632/oncotarget.2484 Ganji Purnachandra Nagaraju, Olatunji B. Alese, Jerome Landry, Roberto Diaz, and Bassel F. El-Rayes |
9980-9991 |
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Galectin-3 leads to attenuation of apoptosis through Bax heterodimerization in human thyroid carcinoma cells |
https://doi.org/10.18632/oncotarget.2486 Yosuke Harazono, Dhong Hyo Kho, Vitaly Balan, Kosei Nakajima, Tianpeng Zhang, Victor Hogan, and Avraham Raz |
9992-10001 |
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Src-dependent phosphorylation at Y406 on the thyroid hormone receptor β confers the tumor suppressor activity |
https://doi.org/10.18632/oncotarget.2487 Jeong Won Park, Li Zhao, Paul Webb, and Sheue-yann Cheng |
10002-10016 |
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Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1 |
https://doi.org/10.18632/oncotarget.2488 Dhanya K. Nambiar, Gagan Deep, Rana P. Singh, Chapla Agarwal, and Rajesh Agarwal |
10017-10033 |
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Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation |
https://doi.org/10.18632/oncotarget.2490 Carolina Simioni, Alice Cani, Alberto M. Martelli, Giorgio Zauli, Giovanna Tabellini, James McCubrey, Silvano Capitani, and Luca M. Neri |
10034-10047 |
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TERT promoter mutations and gene amplification: Promoting TERT expression in Merkel cell carcinoma |
https://doi.org/10.18632/oncotarget.2491 Hong Xie, Tiantian Liu, Na Wang, Viveca Björnhagen, Anders Höög, Catharina Larsson, Weng-Onn Lui, and Dawei Xu |
10048-10057 |
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Differential β2-adrenergic receptor expression defines the phenotype of non-tumorigenic and malignant human breast cell lines |
https://doi.org/10.18632/oncotarget.2460 Lucía Gargiulo, Sabrina Copsel, Ezequiel M. Rivero, Céline Galés, Jean-Michel Sénard, Isabel A. Lüthy, Carlos Davio, and Ariana Bruzzone |
10058-10069 |
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The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signaling |
https://doi.org/10.18632/oncotarget.2458 Layka Abbasi Asbagh, Iria Vazquez, Loredana Vecchione, Eva Budinska, Veerle De Vriendt, Maria Francesca Baietti, Mikhail Steklov, Bart Jacobs, Nicholas Hoe, Sharat Singh, Naga-Sailaja Imjeti, Pascale Zimmermann, Anna Sablina, and Sabine Tejpar |
10070-10083 |
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HAX1 regulates E3 ubiquitin ligase activity of cIAPs by promoting their dimerization |
https://doi.org/10.18632/oncotarget.2459 Jin Sun Choi, Byoung Chul Park, Seung Wook Chi, Kwang-Hee Bae, Sunhong Kim, Sayeon Cho, Woo-Chan Son, Pyung Keun Myung, Jeong-Hoon Kim, and Sung Goo Park |
10084-10099 |
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Intratumoral administration of mRNA encoding a fusokine consisting of IFN-β and the ectodomain of the TGF-β receptor II potentiates antitumor immunity |
https://doi.org/10.18632/oncotarget.2463 Kevin Van der Jeught, Patrick Tjok Joe, Lukasz Bialkowski, Carlo Heirman, Lidia Daszkiewicz, Therese Liechtenstein, David Escors, Kris Thielemans, and Karine Breckpot |
10100-10113 |
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Heptamethine carbocyanine dye-mediated near-infrared imaging of canine and human cancers through the HIF-1α/OATPs signaling axis |
https://doi.org/10.18632/oncotarget.2464 Changhong Shi, Jason Boyang Wu, Gina C-Y. Chu, Qinlong Li, Ruoxiang Wang, Caiqin Zhang, Yi Zhang, Hyung L. Kim, Haiyen E. Zhau, Dongfeng Pan, and Leland W.K. Chung |
10114-10126 |
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TRIM16 inhibits proliferation and migration through regulation of interferon beta 1 in melanoma cells |
https://doi.org/10.18632/oncotarget.2466 Selina K. Sutton, Jessica Koach, Owen Tan, Bing Liu, Daniel R. Carter, James S. Wilmott, Benafsha Yosufi, Lauren E. Haydu, Graham J. Mann, John F. Thompson, Georgina V. Long, Tao Liu, Grant McArthur, Xu Dong Zhang, Richard A. Scolyer, Belamy B. Cheung, and Glenn M. Marshall |
10127-10139 |
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Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway |
https://doi.org/10.18632/oncotarget.2471 Hongyu Zhou, Tao Shen, Chaowei Shang, Yan Luo, Lei Liu, Juming Yan, Yan Li, and Shile Huang |
10140-10150 |
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Functional modification of adipocytes by grape seed extract impairs their pro-tumorigenic signaling on colon cancer stem cells and the daughter cancer cells |
https://doi.org/10.18632/oncotarget.2467 Sushil Kumar, Dileep Kumar, Komal Raina, Rajesh Agarwal, and Chapla Agarwal |
10151-10169 |
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CCR9/CCL25 expression in non-small cell lung cancer correlates with aggressive disease and mediates key steps of metastasis |
https://doi.org/10.18632/oncotarget.2526 Pranav Gupta, Praveen K. Sharma, Hina Mir, Rajesh Singh, Nalinaksha Singh, Goetz H. Kloecker, James W. Lillard, Jr., and Shailesh Singh |
10170-10179 |
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HS-133, a novel fluorescent phosphatidylinositol 3-kinase inhibitor as a potential imaging and anticancer agent for targeted therapy |
https://doi.org/10.18632/oncotarget.2507 Ju-Hee Lee, Kyung Hee Jung, Hyunseung Lee, Mi Kwon Son, Sun-Mi Yun, Sung-Hoon Ahn, Kyeong-Ryoon Lee, Soyoung Lee, Donghee Kim, Sungwoo Hong, and Soon-Sun Hong |
10180-10197 |
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Signaling pathways activation profiles make better markers of cancer than expression of individual genes |
https://doi.org/10.18632/oncotarget.2548 Nikolay M. Borisov, Nadezhda V. Terekhanova, Alexander M. Aliper, Larisa S. Venkova, Philip Yu Smirnov, Sergey Roumiantsev, Mikhail B. Korzinkin, Alex A. Zhavoronkov, and Anton A. Buzdin |
10198-10205 |
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