Oncotarget
Akwasi et al show the computational docking of GANT61 to GLI1 using the known crystal structure of the five zinc finger GLI1-DNA complex.
An updated overview of HPV-associated head and neck carcinomas |
https://doi.org/10.18632/oncotarget.1934 Apostolos Zaravinos |
3956-3969 |
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The nutritional phenome of EMT-induced cancer stem-like cells |
https://doi.org/10.18632/oncotarget.2147 Elisabet Cuyàs, Bruna Corominas-Faja, and Javier A. Menendez |
3970-3982 |
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Influence of tumor microenvironment on prognosis in colorectal cancer: Tissue architecture-dependent signature of endosialin (TEM-1) and associated proteins |
https://doi.org/10.18632/oncotarget.2108 Daniel J. J. O’Shannessy, Elizabeth B. Somers, Lakshmi K. Chandrasekaran, Nicholas C. Nicolaides, Jennifer Bordeaux, and Mark D. Gustavson |
3983-3995 |
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Combined BRAFV600E- and SRC-inhibition induces apoptosis, evokes an immune response and reduces tumor growth in an immunocompetent orthotopic mouse model of anaplastic thyroid cancer |
https://doi.org/10.18632/oncotarget.2130 Pierre Vanden Borre, Viswanath Gunda, David G. McFadden, Peter M. Sadow, Shohreh Varmeh, Maria Bernasconi, and Sareh Parangi |
3996-4010 |
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An interferon signature identified by RNA-sequencing of mammary tissues varies across the estrous cycle and is predictive of metastasis-free survival |
https://doi.org/10.18632/oncotarget.2148 Antoine M. Snijders, Sasha Langley, Jian-Hua Mao, Sandhya Bhatnagar, Kathleen A. Bjornstad, Chris J. Rosen, Alvin Lo, Yurong Huang, Eleanor A. Blakely, Gary H. Karpen, Mina J. Bissell, and Andrew J. Wyrobek |
4011-4025 |
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A genome-wide miRNA screen revealed miR-603 as a MGMT-regulating miRNA in glioblastomas |
https://doi.org/10.18632/oncotarget.1974 Deepa Kushwaha, Valya Ramakrishnan, Kimberly Ng, Tyler Steed, Thien Nguyen, Diahnn Futalan, Johnny C. Akers, Jann Sarkaria, Tao Jiang, Dipanjan Chowdhury, Bob S. Carter, and Clark C. Chen |
4026-4039 |
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Whole genome expression profiling of blood cells in ovarian cancer patients -Prognostic impact of the CYP1B1, MTSS1, NCALD, and NOP14 genes |
https://doi.org/10.18632/oncotarget.1938 Helena S. Isaksson, Bengt Sorbe, and Torbjörn K. Nilsson |
4040-4049 |
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Week one FLT-PET response predicts complete remission to R-CHOP and survival in DLBCL |
https://doi.org/10.18632/oncotarget.1990 Ken Herrmann, Andreas K. Buck, Tibor Schuster, Kathrin Abbrederis, Christina Blümel, Ivan Santi, Martina Rudelius, Hans-Jürgen Wester, Christian Peschel, Markus Schwaiger, Tobias Dechow, and Ulrich Keller |
4050-4059 |
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Potential clinical implications of BRAF mutations in histiocytic proliferations |
https://doi.org/10.18632/oncotarget.2061 Anna-Maria Bubolz, Stephanie E. Weissinger, Albrecht Stenzinger, Annette Arndt, Konrad Steinestel, Silke Brüderlein, Holger Cario, Anneli Lubatschofski, Claudia Welke, Ioannis Anagnostopoulos, Thomas F. E. Barth, Ambros J. Beer, Peter Möller, Martin Gottstein, Andreas Viardot, and Jochen K. Lennerz |
4060-4070 |
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Identification of aurora kinase A as an unfavorable prognostic factor and potential treatment target for metastatic gastrointestinal stromal tumors |
https://doi.org/10.18632/oncotarget.1705 Chun-Nan Yeh, Chueh-Chuan Yen, Yen-Yang Chen, Chi-Tung Cheng, Shih-Chiang Huang, Ting-Wei Chang, Fang-Yi Yao, Yung-Chan Lin, Yao-Shan Wen, Kun-Chun Chiang, Jen-Shi Chen, Ta-Sen Yeh, Cheng-Hwai Tzeng, Ta-Chung Chao, and Jonathan A. Fletcher |
4071-4086 |
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Heme-oxygenase-1 implications in cell morphology and the adhesive behavior of prostate cancer cells |
https://doi.org/10.18632/oncotarget.1826 Geraldine Gueron, Jimena Giudice, Pia Valacco, Alejandra Paez, Belen Elguero, Martin Toscani, Felipe Jaworski, Federico Coluccio Leskow, Javier Cotignola, Marcelo Marti, Maria Binaghi, Nora Navone, and Elba Vazquez |
4087-4102 |
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Silencing of LINE-1 retrotransposons contributes to variation in small noncoding RNA expression in human cancer cells |
https://doi.org/10.18632/oncotarget.1822 Stephen Ohms, and Danny Rangasamy |
4103-4117 |
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Artesunate overcomes drug resistance in multiple myeloma by inducing mitochondrial stress and non-caspase apoptosis |
https://doi.org/10.18632/oncotarget.1847 Xenofon Papanikolaou, Sarah Johnson, Tarun Garg, Erming Tian, Ruslana Tytarenko, Qing Zhang, Caleb Stein, Bart Barlogie, Joshua Epstein, and Christoph Heuck |
4118-4128 |
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Metformin-induced metabolic reprogramming of chemoresistant ALDHbright breast cancer cells |
https://doi.org/10.18632/oncotarget.1864 Mario Cioce, MariaCristina Valerio, Luca Casadei, Claudio Pulito, Andrea Sacconi, Federica Mori, Francesca Biagioni, Cesare Manetti, Paola Muti, Sabrina Strano, and Giovanni Blandino |
4129-4143 |
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Loss of tumor suppressor mir-203 mediates overexpression of LIM and SH3 Protein 1 (LASP1) in high-risk prostate cancer thereby increasing cell proliferation and migration |
https://doi.org/10.18632/oncotarget.1928 Amelie Hailer, Thomas GP Grunewald, Martin Orth, Cora Reiss, Burkhard Kneitz, Martin Spahn, and Elke Butt |
4144-4153 |
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Urokinase receptor promotes ovarian cancer cell dissemination through its 84-95 sequence |
https://doi.org/10.18632/oncotarget.1930 Katia Bifulco, Giuseppina Votta, Vincenzo Ingangi, Gioconda Di Carluccio, Domenica Rea, Simona Losito, Nunzia Montuori, Pia Ragno, Maria Patrizia Stoppelli, Claudio Arra, and Maria Vincenza Carriero |
4154-4169 |
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The poison oligonucleotide F10 is highly effective against acute lymphoblastic leukemia while sparing normal hematopoietic cells |
https://doi.org/10.18632/oncotarget.1937 Timothy S. Pardee, Kristin Stadelman, Jamie Jennings-Gee, David L. Caudell, and William H. Gmeiner |
4170-4179 |
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Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells |
https://doi.org/10.18632/oncotarget.1944 Wei Qian, Jingnan Wang, Vera Roginskaya, Lee A. McDermott, Robert P. Edwards, Donna B. Stolz, Fabien Llambi, Douglas R. Green, and Bennett Van Houten |
4180-4194 |
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Repression of liver colorectal metastasis by the serpin Spn4A a naturally occurring inhibitor of the constitutive secretory proprotein convertases |
https://doi.org/10.18632/oncotarget.1966 Fatma Sfaxi, Nathalie Scamuffa, Claude Lalou, Jia Ma, Peter Metrakos, Géraldine Siegfried, Hermann Ragg, Andreas Bikfalvi, Fabien Calvo, and Abdel-Majid Khatib |
4195-4210 |
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SCFβ-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination |
https://doi.org/10.18632/oncotarget.1971 Xiaomian Wu, Hidefumi Fukushima, Brian J. North, Yoshiyuki Nagaoka, Katsuyuki Nagashima, Feng Deng, Koji Okabe, Hiroyuki Inuzuka, and Wenyi Wei |
4211-4221 |
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PLC-beta 1 regulates the expression of miR-210 during mithramycin-mediated erythroid differentiation in K562 cells |
https://doi.org/10.18632/oncotarget.1972 Alberto Bavelloni, Alessandro Poli, Roberta Fiume, William Blalock, Alessandro Matteucci, Giulia Ramazzotti, James A. McCubrey, Lucio Cocco, and Irene Faenza |
4222-4231 |
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Post-translational regulation of COX2 activity by FYN in prostate cancer cells |
https://doi.org/10.18632/oncotarget.1983 Anna Alexanian, Bradley Miller, Marla Chesnik, Shama Mirza, and Andrey Sorokin |
4232-4243 |
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Reduced ING1 levels in breast cancer promotes metastasis |
https://doi.org/10.18632/oncotarget.1988 Satbir Thakur, Arvind K. Singla, Jie Chen, Uyen Tran, Yang Yang, Carolina Salazar, Anthony Magliocco, Alexander Klimowicz, Frank R. Jirik, and Karl Riabowol |
4244-4256 |
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Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1 |
https://doi.org/10.18632/oncotarget.1991 Jeyran Shahbazi, Christopher J. Scarlett, Murray D. Norris, Bing Liu, Michelle Haber, Andrew E. Tee, Alice Carrier, Andrew V. Biankin, Wendy B. London, Glenn M. Marshall, Richard B. Lock, and Tao Liu |
4257-4268 |
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Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer |
https://doi.org/10.18632/oncotarget.2001 Xiaomei Qi, Congying Xie, Songwang Hou, Gang Li, Ning Yin, Lei Dong, Adrienne Lepp, Marla A. Chesnik, Shama P. Mirza, Aniko Szabo, Susan Tsai, Zainab Basir, Shixiu Wu, and Guan Chen |
4269-4282 |
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Increased Nek1 expression in Renal Cell Carcinoma cells is associated with decreased sensitivity to DNA-damaging treatment |
https://doi.org/10.18632/oncotarget.2005 Yumay Chen, Chi-Fen Chen, Rosaria Polci, Randy Wei, Daniel J. Riley, and Phang-Lang Chen |
4283-4294 |
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Relevance of IGFBP2 proteolysis in glioma and contribution of the extracellular protease ADAMTS1 |
https://doi.org/10.18632/oncotarget.2009 Estefanía Martino-Echarri, Rubén Fernández-Rodríguez, Joan Josep Bech-Serra, María del Carmen Plaza-Calonge, Noemi Vidal, Carmen Casal, Nuria Colomé, Joan Seoane, Francesc Canals, and Juan Carlos Rodríguez-Manzaneque |
4295-4304 |
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Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation |
https://doi.org/10.18632/oncotarget.2010 Anna Pastò, Chiara Bellio, Giorgia Pilotto, Vincenzo Ciminale, Micol Silic-Benussi, Giulia Guzzo, Andrea Rasola, Chiara Frasson, Giorgia Nardo, Elisabetta Zulato, Maria Ornella Nicoletto, Mariangela Manicone, Stefano Indraccolo, and Alberto Amadori |
4305-4319 |
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High nuclear level of Vav1 is a positive prognostic factor in early invasive breast tumors: a role in modulating genes related to the efficiency of metastatic process |
https://doi.org/10.18632/oncotarget.2011 Silvia Grassilli, Federica Brugnoli, Rossano Lattanzio, Cosmo Rossi, Letizia Perracchio, Marcella Mottolese, Marco Marchisio, Maria Palomba, Ervin Nika, Pier Giorgio Natali, Mauro Piantelli, Silvano Capitani, and Valeria Bertagnolo |
4320-4336 |
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XIAP inhibitors induce differentiation and impair clonogenic capacity of acute myeloid leukemia stem cells |
https://doi.org/10.18632/oncotarget.2016 Daniel Moreno-Martínez, Meritxell Nomdedeu, María Carmen Lara-Castillo, Amaia Etxabe, Marta Pratcorona, Niccolò Tesi, Marina Díaz-Beyá, María Rozman, Emili Montserrat, Álvaro Urbano-Ispizua, Jordi Esteve, and Ruth M. Risueño |
4337-4346 |
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Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3 |
https://doi.org/10.18632/oncotarget.2018 Chiara Agnoletto, Elisabetta Melloni, Fabio Casciano, Gian Matteo Rigolin, Erika Rimondi, Claudio Celeghini, Laura Brunelli, Antonio Cuneo, Paola Secchiero, and Giorgio Zauli |
4347-4360 |
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DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response |
https://doi.org/10.18632/oncotarget.2020 Laureen Colis, Karita Peltonen, Paul Sirajuddin, Hester Liu, Sara Sanders, Glen Ernst, James C. Barrow, and Marikki Laiho |
4361-4369 |
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SCFFBXW7α modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stability |
https://doi.org/10.18632/oncotarget.2021 Servando Giráldez, Joaquín Herrero-Ruiz, Mar Mora-Santos, Miguel Á. Japón, Maria Tortolero, and Francisco Romero |
4370-4383 |
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Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines |
https://doi.org/10.18632/oncotarget.2024 Thomas Cluzeau, Alix Dubois, Arnaud Jacquel, Frederic Luciano, Aline Renneville, Claude Preudhomme, Jean Michel Karsenti, Nicolas Mounier, Pierre Rohrlich, Sophie Raynaud, Bernard Mari, Guillaume Robert, and Patrick Auberger |
4384-4391 |
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NOX4 promotes non-small cell lung cancer cell proliferation and metastasis through positive feedback regulation of PI3K/Akt signaling |
https://doi.org/10.18632/oncotarget.2025 Cuixiang Zhang, Tian Lan, Jincai Hou, Juan Li, Rende Fang, Zhicheng Yang, Min Zhang, Jianxun Liu, and Bing Liu |
4392-4405 |
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Rac1 regulates skin tumors by regulation of keratin 17 through recruitment and interaction with CD11b+Gr1+ cells |
https://doi.org/10.18632/oncotarget.2030 Rongyi Chen, Meng Fu, Guoxue Zhang, Ying Zhou, Shaojun Zhu, Juanjuan Liu, Dong Wang, Anmei Deng, and Zhipeng Wang |
4406-4417 |
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Thymocyte selection-associated high mobility group box gene (TOX) is aberrantly over-expressed in mycosis fungoides and correlates with poor prognosis |
https://doi.org/10.18632/oncotarget.2031 Yuanshen Huang, Ivan V. Litvinov, Yang Wang, Ming-Wan Su, Ping Tu, Xiaoyan Jiang, Thomas S. Kupper, Jan P. Dutz, Denis Sasseville, and Youwen Zhou |
4418-4425 |
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Apelin promotes lymphangiogenesis and lymph node metastasis |
https://doi.org/10.18632/oncotarget.2032 Judit Berta, Mir Alireza Hoda, Viktoria Laszlo, Anita Rozsas, Tamas Garay, Szilvia Torok, Michael Grusch, Walter Berger, Sandor Paku, Ferenc Renyi-Vamos, Bernard Masri, Jozsef Tovari, Marion Groger, Walter Klepetko, Balazs Hegedus, and Balazs Dome |
4426-4437 |
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20(S)-Ginsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin |
https://doi.org/10.18632/oncotarget.2034 Dong-Gun Kim, Kyung Hee Jung, Da-Gyum Lee, Jung-Ho Yoon, Kyeong Sook Choi, Sung Won Kwon, Han-Ming Shen, Michael J. Morgan, Soon-Sun Hong, and You-Sun Kim |
4438-4451 |
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Wild-type ALK and activating ALK-R1275Q and ALK-F1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cells |
https://doi.org/10.18632/oncotarget.2036 Gisèle Montavon, Nicolas Jauquier, Aurélie Coulon, Michel Peuchmaur, Marjorie Flahaut, Katia Balmas Bourloud, Pu Yan, Olivier Delattre, Lukas Sommer, Jean-Marc Joseph, Isabelle Janoueix-Lerosey, Nicole Gross, and Annick Mühlethaler-Mottet |
4452-4466 |
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Host defense peptides for treatment of colorectal carcinoma – a comparative in vitro and in vivo analysis |
https://doi.org/10.18632/oncotarget.2039 Claudia Maletzki, Ulrike Klier, Samuel Marinkovic, Ernst Klar, Jörg Andrä, and Michael Linnebacher |
4467-4479 |
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PD2/Paf1 depletion in pancreatic acinar cells promotes acinar-to-ductal metaplasia |
https://doi.org/10.18632/oncotarget.2041 Parama Dey, Satyanarayana Rachagani, Arokia P. Vaz, Moorthy P. Ponnusamy, and Surinder K. Batra |
4480-4491 |
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Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding |
https://doi.org/10.18632/oncotarget.2046 Akwasi Agyeman, Babal K. Jha, Tapati Mazumdar, and Janet A. Houghton |
4492-4503 |
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New histone deacetylase inhibitors improve cisplatin antitumor properties against thoracic cancer cells |
https://doi.org/10.18632/oncotarget.2056 Fabien Gueugnon, Pierre-François Cartron, Cedric Charrier, Philippe Bertrand, Jean-François Fonteneau, Marc Gregoire, and Christophe Blanquart |
4504-4515 |
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Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals |
https://doi.org/10.18632/oncotarget.2065 Laura Gatti, Alexandra Sevko, Michelandrea De Cesare, Noemi Arrighetti, Giacomo Manenti, Emilio Ciusani, Paolo Verderio, Chiara M. Ciniselli, Denis Cominetti, Nives Carenini, Elisabetta Corna, Nadia Zaffaroni, Monica Rodolfo, Licia Rivoltini, Viktor Umansky, and Paola Perego |
4516-4528 |
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Icotinib antagonizes ABCG2-mediated multidrug resistance, but not the pemetrexed resistance mediated by thymidylate synthase and ABCG2 |
https://doi.org/10.18632/oncotarget.2102 De-Shen Wang, Atish Patel, Suneet Shukla, Yun-Kai Zhang, Yi-Jun Wang, Rishil J. Kathawala, Robert W. Robey, Li Zhang, Dong-Hua Yang, Tanaji T. Talele, Susan E. Bates, Suresh V. Ambudkar, Rui-Hua Xu, and Zhe-Sheng Chen |
4529-4542 |
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Discovery of novel non-ATP competitive FGFR1 inhibitors and evaluation of their anti-tumor activity in non-small cell lung cancer in vitro and in vivo |
https://doi.org/10.18632/oncotarget.2122 Jianzhang Wu, Jiansong Ji, Bixia Weng, Peihong Qiu, Karvannan Kanchana, Tao Wei, Yi Wang, Yuepiao Cai, Xiaokun Li, and Guang Liang |
4543-4553 |
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Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB |
https://doi.org/10.18632/oncotarget.2128 Yulia N. Demchenko, Leslie A. Brents, Zhihong Li, Leif P. Bergsagel, Lawrence R. McGee, and Michael W. Kuehl |
4554-4566 |
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Targeted cytotoxic analog of luteinizing hormone-releasing hormone (LHRH), AEZS-108 (AN-152), inhibits the growth of DU-145 human castration-resistant prostate cancer in vivo and in vitro through elevating p21 and ROS levels |
https://doi.org/10.18632/oncotarget.2146 Petra Popovics, Andrew V. Schally, Luca Szalontay, Norman L. Block, and Ferenc G. Rick |
4567-4578 |
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