Oncotarget

Vol 10, No 4

January 11, 2019

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About The Cover

The cover for issue 4 of Oncotarget features Figure 6, "Bliss Independence analysis to evaluate synergistic activity between ABT-263 (navitoclax) and A-1210477," by Ow, et al.

Table of Contents

Editorial

Individualized prognostic calculators in the precision oncology era

Individualized prognostic calculators in the precision oncology era

https://doi.org/10.18632/oncotarget.26581

Jeremy M.G. Taylor, Andrew G. Shuman,  and Lauren J. Beesley
415-416
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Research Perspectives

The effects of genomic germline variant reclassification on clinical cancer care

The effects of genomic germline variant reclassification on clinical cancer care

https://doi.org/10.18632/oncotarget.26501

Thomas P. Slavin, Sophia Manjarrez, Colin C. Pritchard, Stacy Gray,  and Jeffrey N. Weitzel
417-423
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Research Papers

Inhibition of 5-lipoxygenase downregulates stemness and kills prostate cancer stem cells by triggering apoptosis via activation of c-Jun N-terminal kinase

Inhibition of 5-lipoxygenase downregulates stemness and kills prostate cancer stem cells by triggering apoptosis via activation of c-Jun N-terminal kinase

https://doi.org/10.18632/oncotarget.13422

Sivalokanathan Sarveswaran, Nadimpalli R.S. Varma, Shravan Morisetty,  and Jagadananda Ghosh
424-436
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A single-center experience of post-transplant lymphomas involving the central nervous system with a review of current literature

A single-center experience of post-transplant lymphomas involving the central nervous system with a review of current literature

https://doi.org/10.18632/oncotarget.26522

Anju John John Velvet, Shiv Bhutani, Stavros Papachristos, Reena Dwivedi, Michael Picton, Titus Augustine,  and Muir Morton
437-448
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Imbalanced sphingolipid signaling is maintained as a core proponent of a cancerous phenotype in spite of metabolic pressure and epigenetic drift

Imbalanced sphingolipid signaling is maintained as a core proponent of a cancerous phenotype in spite of metabolic pressure and epigenetic drift

https://doi.org/10.18632/oncotarget.26533

Monique M.P. Speirs, Adam C. Swensen, Tsz Y. Chan, Peter M. Jones, John C. Holman, McCall B. Harris, John A. Maschek, James E. Cox, Richard H. Carson, Jonathon T. Hill, Joshua L. Andersen, John T. Prince,  and John C. Price
449-479
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Fibroblast growth factor receptor 1 (FGFR1) as a therapeutic target in adenoid cystic carcinoma of the lacrimal gland

Fibroblast growth factor receptor 1 (FGFR1) as a therapeutic target in adenoid cystic carcinoma of the lacrimal gland

https://doi.org/10.18632/oncotarget.26558

Ravi Doddapaneni, Wensi Tao, Andrea Naranjo, Neda Nikpoor, David T. Tse,  and Daniel Pelaez
480-493
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Optimal targeting of BCL-family proteins in head and neck squamous cell carcinoma requires inhibition of both BCL-xL and MCL-1

Optimal targeting of BCL-family proteins in head and neck squamous cell carcinoma requires inhibition of both BCL-xL and MCL-1

https://doi.org/10.18632/oncotarget.26563

Thomas J. Ow, Cory D. Fulcher, Carlos Thomas, Pilib Ó Broin, Andrea López, Denis E. Reyna, Richard V. Smith, Catherine Sarta, Michael B. Prystowsky, Nicolas F. Schlecht, Bradley A. Schiff, Gregory Rosenblatt, Thomas J. Belbin, Thomas M. Harris, Geoffrey C. Childs, Nicole Kawachi, Chandan Guha,  and Evripidis Gavathiotis
494-510
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Serum amyloid A predisposes inflammatory tumor microenvironment in triple negative breast cancer

Serum amyloid A predisposes inflammatory tumor microenvironment in triple negative breast cancer

https://doi.org/10.18632/oncotarget.26566

Rosa Mistica C. Ignacio, Carla R. Gibbs, Soohyun Kim, Eun-Sook Lee, Samuel E. Adunyah,  and Deok-Soo Son
511-526
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  How to cite  |  Order a Reprint

Polymorphism of DNA repair genes in breast cancer

Polymorphism of DNA repair genes in breast cancer

https://doi.org/10.18632/oncotarget.26568

Beata Smolarz, Magdalena M. Michalska, Dariusz Samulak, Hanna Romanowicz,  and Luiza Wójcik
527-535
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A structural model of the immune checkpoint CD160–HVEM complex derived from HDX-mass spectrometry and molecular modeling

A structural model of the immune checkpoint CD160–HVEM complex derived from HDX-mass spectrometry and molecular modeling

https://doi.org/10.18632/oncotarget.26570

Katarzyna Kuncewicz, Marta Spodzieja, Adam Sieradzan, Agnieszka Karczyńska, Katarzyna Dąbrowska, Michał Dadlez, Daniel E. Speiser, Laurent Derre,  and Sylwia Rodziewicz-Motowidło
536-550
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Case Reports

Sustained response of three pediatric BRAFV600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy

Sustained response of three pediatric BRAFV600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy

https://doi.org/10.18632/oncotarget.26560

Stephanie A. Toll, Hung N. Tran, Jennifer Cotter, Alexander R. Judkins, Benita Tamrazi, Jaclyn A Biegel, Girish Dhall, Nathan J. Robison, Kaaren Waters, Palak Patel, Robert Cooper,  and Ashley S. Margol
551-557
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Corrections

Correction: Prorenin receptor acts as a potential molecular target for pancreatic ductal adenocarcinoma diagnosis

Correction: Prorenin receptor acts as a potential molecular target for pancreatic ductal adenocarcinoma diagnosis

https://doi.org/10.18632/oncotarget.26597

Arivajiagane Arundhathi, Wen-Han Chuang, Jen-Kun Chen, Shin-E Wang, Yi-Ming Shyr, Jiun-Yu Chen, Wei-Neng Liao, Hsin-Wei Chen, Yi-Min Teng, Chiao-Chih Pai,  and Chih-Hong Wang
558-558
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