Oncotarget

Vol 9, No 76

September 28, 2018

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About The Cover

The cover for issue 76 of Oncotarget features Figure 2, "The identification of TTGM 5826 as a potential modulator of tTG conformation," by Katt, et al.

Table of Contents

News

Gadd45 stress sensors in suppression of leukemia

Gadd45 stress sensors in suppression of leukemia

https://doi.org/10.18632/oncotarget.26154

David L. Wiest
34191-34192
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Editorial

CDK4/6 inhibitors in hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer: Are we at the finish line?

CDK4/6 inhibitors in hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer: Are we at the finish line?

https://doi.org/10.18632/oncotarget.26134

Clinton Yam, Mien-Chie Hung,  and Gabriel N. Hortobagyi
34193-34195
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Metastasis-directed therapy: a new standard for oligorecurrent prostate cancer?

Metastasis-directed therapy: a new standard for oligorecurrent prostate cancer?

https://doi.org/10.18632/oncotarget.26152

Thomas Zilli,  and Piet Ost
34196-34197
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The ubiquitin-activating enzyme, UBA1, as a novel therapeutic target for AML

The ubiquitin-activating enzyme, UBA1, as a novel therapeutic target for AML

https://doi.org/10.18632/oncotarget.26153

Samir H. Barghout,  and Aaron D. Schimmer
34198-34199
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Research Papers

Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2

Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2

https://doi.org/10.18632/oncotarget.24409

Li Wang, Yujuan Zhang, Kangdong Liu, Hanyong Chen, Ran Yang, Xiaoli Ma, Hong-Gyum Kim, Ann M. Bode, Dong Joon Kim,  and Zigang Dong
34200-34212
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Clearance of HBeAg and HBsAg of HBV in mice model by a recombinant HBV vaccine combined with GM-CSF and IFN-α as an effective therapeutic vaccine adjuvant

Clearance of HBeAg and HBsAg of HBV in mice model by a recombinant HBV vaccine combined with GM-CSF and IFN-α as an effective therapeutic vaccine adjuvant

https://doi.org/10.18632/oncotarget.25789

Weidong Zhao, Gan Zhao, Shuren Zhang, Xianzheng Wang, Xueping Yu,  and Bin Wang
34213-34228
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Inactive immune pathways in triple negative breast cancers that showed resistance to neoadjuvant chemotherapy as inferred from kinase activity profiles

Inactive immune pathways in triple negative breast cancers that showed resistance to neoadjuvant chemotherapy as inferred from kinase activity profiles

https://doi.org/10.18632/oncotarget.26026

Takeshi Sawada, Riet Hilhorst, Savithri Rangarajan, Masayuki Yoshida, Yuko Tanabe, Kenji Tamura, Takayuki Kinoshita, Tatsu Shimoyama, Rinie van Beuningen, Rob Ruijtenbeek, Hitoshi Tsuda,  and Fumiaki Koizumi
34229-34239
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Heat shock protein 90 inhibitors overcome the resistance to Fms-like tyrosine kinase 3 inhibitors in acute myeloid leukemia

Heat shock protein 90 inhibitors overcome the resistance to Fms-like tyrosine kinase 3 inhibitors in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.26045

Kazuhiro Katayama, Kohji Noguchi,  and Yoshikazu Sugimoto
34240-34258
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The role of AP-1 in self-sufficient proliferation and migration of cancer cells and its potential impact on an autocrine/paracrine loop

The role of AP-1 in self-sufficient proliferation and migration of cancer cells and its potential impact on an autocrine/paracrine loop

https://doi.org/10.18632/oncotarget.26047

Sherif Abd El-Fattah Ibrahim, Aierken Abudu, Eugenia Jonhson, Neelum Aftab, Susan Conrad,  and Michele Fluck
34259-34278
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Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach

Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach

https://doi.org/10.18632/oncotarget.26081

Sofía del Carmen, José María Sayagués, Oscar Bengoechea, María Fernanda Anduaga, Jose Antonio Alcazar, Ruth Gervas, Jacinto García, Alberto Orfao, Luis Muñoz Bellvis, María Eugenia Sarasquete,  and María del Mar Abad
34279-34288
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Molecular dynamics simulation reveals the possible druggable hot-spots of USP7

Molecular dynamics simulation reveals the possible druggable hot-spots of USP7

https://doi.org/10.18632/oncotarget.26136

Mitul Srivastava, Charu Suri, Mrityunjay Singh, Rajani Mathur,  and Shailendra Asthana
34289-34305
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Oncogenic driver FGFR3-TACC3 is dependent on membrane trafficking and ERK signaling

Oncogenic driver FGFR3-TACC3 is dependent on membrane trafficking and ERK signaling

https://doi.org/10.18632/oncotarget.26142

Katelyn N. Nelson, April N. Meyer, Clark G. Wang,  and Daniel J. Donoghue
34306-34319
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Overexpression of KDM5B/JARID1B is associated with poor prognosis in hepatocellular carcinoma

Overexpression of KDM5B/JARID1B is associated with poor prognosis in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.26144

Yoshinobu Shigekawa, Shinya Hayami, Masaki Ueno, Atsushi Miyamoto, Norihiko Suzaki, Manabu Kawai, Seiko Hirono, Ken-ichi Okada, Ryuji Hamamoto,  and Hiroki Yamaue
34320-34335
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The efficacy of re-challenge with BRAF inhibitors after previous progression to BRAF inhibitors in melanoma: A retrospective multicenter study

The efficacy of re-challenge with BRAF inhibitors after previous progression to BRAF inhibitors in melanoma: A retrospective multicenter study

https://doi.org/10.18632/oncotarget.26149

Julia K. Tietze, Andrea Forschner, Carmen Loquai, Heidrun Mitzel-Rink, Lisa Zimmer, Frank Meiss, David Rafei-Shamsabadi, Jochen Utikal, Maike Bergmann, Friedegund Meier, Nicole Kreuzberg, Max Schlaak, Carsten Weishaupt, Claudia Pföhler, Mirjana Ziemer, Michael Fluck, Jessica Rainer, Markus V. Heppt,  and Carola Berking
34336-34346
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Vitamin D receptor as a marker of prognosis in oesophageal adenocarcinoma: a prospective cohort study

Vitamin D receptor as a marker of prognosis in oesophageal adenocarcinoma: a prospective cohort study

https://doi.org/10.18632/oncotarget.26151

Stephen McCain, James Trainor, Damian T. McManus, Úna C. McMenamin, Stephen McQuaid, Victoria Bingham, Jacqueline A. James, Manuel Salto-Tellez, Richard C. Turkington,  and Helen G. Coleman
34347-34356
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Functional characterization of phospholipase C-γ2 mutant protein causing both somatic ibrutinib resistance and a germline monogenic autoinflammatory disorder

Functional characterization of phospholipase C-γ2 mutant protein causing both somatic ibrutinib resistance and a germline monogenic autoinflammatory disorder

https://doi.org/10.18632/oncotarget.26173

Claudia Walliser, Martin Wist, Elisabeth Hermkes, Yuan Zhou, Anja Schade, Jennifer Haas, Julia Deinzer, Laurent Désiré, Shawn S.C. Li, Stephan Stilgenbauer, Joshua D. Milner,  and Peter Gierschik
34357-34378
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A small molecule regulator of tissue transglutaminase conformation inhibits the malignant phenotype of cancer cells

A small molecule regulator of tissue transglutaminase conformation inhibits the malignant phenotype of cancer cells

https://doi.org/10.18632/oncotarget.26193

William P. Katt, Nicolas J. Blobel, Svetlana Komarova, Marc A. Antonyak, Ichiro Nakano,  and Richard A. Cerione
34379-34397
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Reviews

Biological significance and prognostic/predictive impact of complex karyotype in chronic lymphocytic leukemia

Biological significance and prognostic/predictive impact of complex karyotype in chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.26146

Maurizio Cavallari, Francesco Cavazzini, Antonella Bardi, Eleonora Volta, Aurora Melandri, Elisa Tammiso, Elena Saccenti, Enrico Lista, Francesca Maria Quaglia, Antonio Urso, Michele Laudisi, Elisa Menotti, Luca Formigaro, Melissa Dabusti, Maria Ciccone, Paolo Tomasi, Massimo Negrini, Antonio Cuneo,  and Gian Matteo Rigolin
34398-34412
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genes involved in the regulation of different types of autophagy and their participation in cancer pathogenesis

Genes involved in the regulation of different types of autophagy and their participation in cancer pathogenesis

https://doi.org/10.18632/oncotarget.26126

Martyna Bednarczyk, Nikola Zmarzły, Beniamin Grabarek, Urszula Mazurek,  and Małgorzata Muc-Wierzgoń
34413-34428
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Prominent role of histone lysine demethylases in cancer epigenetics and therapy

Prominent role of histone lysine demethylases in cancer epigenetics and therapy

https://doi.org/10.18632/oncotarget.24319

Avilala Janardhan, Chandrasekhar Kathera, Amrutha Darsi, Wajid Ali, Lingfeng He, Yanhua Yang, Libo Luo,  and Zhigang Guo
34429-34448
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Corrections

Correction: Acute myeloid leukemia with t(4;12)(q12;p13): an aggressive disease with frequent involvement of PDGFRA and ETV6

Correction: Acute myeloid leukemia with t(4;12)(q12;p13): an aggressive disease with frequent involvement of PDGFRA and ETV6

https://doi.org/10.18632/oncotarget.26205

Jingyi Li, Jie Xu, Lynne V. Abruzzo, Guilin Tang, Shaoying Li, M. James You, Gary Lu, Elias J. Jabbour, Qi Deng, Carlos E. Bueso-Ramos, L. Jeffrey Medeiros,  and C. Cameron Yin
34449-34449
Correction  |  PDF

Errata

Erratum: Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB

Erratum: Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB

https://doi.org/10.18632/oncotarget.26206

Vasilisa Aksenova, Lidia Turoverova, Mikhail Khotin, Karl-Eric Magnusson, Eugene Tulchinsky, Gerry Melino, George P. Pinaev, Nickolai Barlev,  and Dmitri Tentler
34450-34450
Erratum  |  PDF


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