Oncotarget

Vol 9, No 70

September 7, 2018

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About The Cover

The cover for issue 70 of Oncotarget features Figure 4B, "BRAF/MEK inhibitor-based phase 1 trial therapy according to BRAF or KRAS hotspot mutation status," by Wang, et al.

Table of Contents

News

Drug repurposing using high-throughput screening identifies a promising drug combination to treat adrenocortical carcinoma

Drug repurposing using high-throughput screening identifies a promising drug combination to treat adrenocortical carcinoma

https://doi.org/10.18632/oncotarget.26091

Antonio M. Lerario,  and Gary D. Hammer
33245-33246
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Editorial

The role of p16 as a biomarker in nonoropharyngeal head and neck cancer

The role of p16 as a biomarker in nonoropharyngeal head and neck cancer

https://doi.org/10.18632/oncotarget.26053

Lucas K. Vitzthum,  and Loren K. Mell
33247-33248
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Priority Research Papers

Modeling and antitumor studies of a modified L–penetratin peptide targeting E2F in lung cancer and prostate cancer

Modeling and antitumor studies of a modified L–penetratin peptide targeting E2F in lung cancer and prostate cancer

https://doi.org/10.18632/oncotarget.26064

Tazeem Shaik, Gulam M, Rather, Nitu Bansal, Tamara Minko, Olga Garbuzenko, Zoltan Szekely, Emine E. Abali, Debabrata Banerjee, John E. Kerrigan, Kathleen W. Scotto,  and Joseph R. Bertino
33249-33257
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Research Papers

Outcome analysis of Phase I trial patients with metastatic KRAS and/or TP53 mutant non-small cell lung cancer

Outcome analysis of Phase I trial patients with metastatic KRAS and/or TP53 mutant non-small cell lung cancer

https://doi.org/10.18632/oncotarget.25947

Yudong Wang, Zhijie Wang, Sarina Piha-Paul, Filip Janku, Vivek Subbiah, Naiyi Shi, Kenneth Hess, Russell Broaddus, Baoen Shan, Aung Naing, David Hong, Apostolia M. Tsimberidou, Daniel Karp, Charles Lu, Vali Papadimitrakopoulou, John Heymach, Funda Meric-Bernstam,  and Siqing Fu
33258-33270
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Glioblastoma in the setting of prior lower grade gliomas – insights from SEER database

Glioblastoma in the setting of prior lower grade gliomas – insights from SEER database

https://doi.org/10.18632/oncotarget.26014

Ha Son Nguyen, Benjamin Best, Ninh B. Doan, Michael Gelsomino, Saman Shabani, Ahmed J. Awad, Mayank Kaushal,  and Martin M. Mortazavi
33271-33277
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Metabolite quantification of faecal extracts from colorectal cancer patients and healthy controls

Metabolite quantification of faecal extracts from colorectal cancer patients and healthy controls

https://doi.org/10.18632/oncotarget.26022

Gwénaëlle Le Gall, Kiran Guttula, Lee Kellingray, Adrian J. Tett, Rogier ten Hoopen, Kate E. Kemsley, George M. Savva, Ashraf Ibrahim,  and Arjan Narbad
33278-33289
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Single-cell transcriptomes reveal the mechanism for a breast cancer prognostic gene panel

Single-cell transcriptomes reveal the mechanism for a breast cancer prognostic gene panel

https://doi.org/10.18632/oncotarget.26044

Shengwen Calvin Li, Andres Stucky, Xuelian Chen, Mustafa H. Kabeer, William G. Loudon, Ashley S. Plant, Lilibeth Torno, Chaitali S. Nangia, Jin Cai, Gang Zhang,  and Jiang F. Zhong
33290-33301
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The vesicular transfer of CLIC1 from glioblastoma to microvascular endothelial cells requires TRPM7

The vesicular transfer of CLIC1 from glioblastoma to microvascular endothelial cells requires TRPM7

https://doi.org/10.18632/oncotarget.26048

Dominique Thuringer, Gaetan Chanteloup, Pascale Winckler,  and Carmen Garrido
33302-33311
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Role of textural heterogeneity parameters in patient selection for 177Lu-PSMA therapy via response prediction

Role of textural heterogeneity parameters in patient selection for 177Lu-PSMA therapy via response prediction

https://doi.org/10.18632/oncotarget.26051

Zain Khurshid, Hojjat Ahmadzadehfar, Florian C. Gaertner, László Papp, Norbert Zsóter, Markus Essler,  and Ralph A. Bundschuh
33312-33321
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A safety study of newly generated anti-podoplanin-neutralizing antibody in cynomolgus monkey (Macaca fascicularis)

A safety study of newly generated anti-podoplanin-neutralizing antibody in cynomolgus monkey (Macaca fascicularis)

https://doi.org/10.18632/oncotarget.26055

Takao Ukaji, Ai Takemoto, Ryohei Katayama, Kengo Takeuchi,  and Naoya Fujita
33322-33336
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Intratumor heterogeneity of HMCN1 mutant alleles associated with poor prognosis in patients with breast cancer

Intratumor heterogeneity of HMCN1 mutant alleles associated with poor prognosis in patients with breast cancer

https://doi.org/10.18632/oncotarget.26071

Chie Kikutake, Minako Yoshihara, Tetsuya Sato, Daisuke Saito,  and Mikita Suyama
33337-33347
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Assessing the efficacy of androgen receptor and Sox10 as independent markers of the triple-negative breast cancer subtype by transcriptome profiling

Assessing the efficacy of androgen receptor and Sox10 as independent markers of the triple-negative breast cancer subtype by transcriptome profiling

https://doi.org/10.18632/oncotarget.26072

Khalid N. Al-Zahrani, David P. Cook, Barbara C. Vanderhyden,  and Luc A. Sabourin
33348-33359
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Loss of Gadd45b accelerates BCR-ABL-driven CML

Loss of Gadd45b accelerates BCR-ABL-driven CML

https://doi.org/10.18632/oncotarget.26076

Xiaojin Sha, Barbara Hoffman,  and Dan A. Liebermann
33360-33367
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N-(2´-Hydroxyphenyl)-2-propylpentanamide (OH-VPA), a histone deacetylase inhibitor, induces the release of nuclear HMGB1 and modifies ROS levels in HeLa cells

N-(2´-Hydroxyphenyl)-2-propylpentanamide (OH-VPA), a histone deacetylase inhibitor, induces the release of nuclear HMGB1 and modifies ROS levels in HeLa cells

https://doi.org/10.18632/oncotarget.26077

Arturo Contis-Montes de Oca, Estefanía Rodarte-Valle, Martha Cecilia Rosales-Hernández, Edgar Abarca-Rojano, Saúl Rojas-Hernández, Manuel Jonathan Fragoso-Vázquez, Jessica Elena Mendieta-Wejebe, Ana María Correa-Basurto, Ismael Vázquez-Moctezuma,  and José Correa-Basurto
33368-33381
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Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinib

Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinib

https://doi.org/10.18632/oncotarget.26078

James A. MacLeod, Yan Gao, Christine Hall, William J. Muller, Taranjit S. Gujral,  and Peter A. Greer
33382-33395
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Meta-Analysis

Meta-analysis of the likelihood of FOXC2 expression in early- and late-stage tumors

Meta-analysis of the likelihood of FOXC2 expression in early- and late-stage tumors

https://doi.org/10.18632/oncotarget.26087

Tsutomu Kume,  and Tarek Shackour
33396-33402
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Reviews

Cancer stem cells in progression of colorectal cancer

Cancer stem cells in progression of colorectal cancer

https://doi.org/10.18632/oncotarget.23607

Yujuan Zhou, Longzheng Xia, Heran Wang, Linda Oyang, Min Su, Qiang Liu, Jingguan Lin, Shiming Tan, Yutong Tian, Qianjin Liao,  and Deliang Cao
33403-33415
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Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy

Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy

https://doi.org/10.18632/oncotarget.26058

Jack W. Singer, Angela Fleischman, Suliman Al-Fayoumi, John O. Mascarenhas, Qiang Yu,  and Anupriya Agarwal
33416-33439
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Corrections

Correction: Checkpoint inhibitor induced cardiotoxicity: managing the drawbacks of our newest agents against cancer

Correction: Checkpoint inhibitor induced cardiotoxicity: managing the drawbacks of our newest agents against cancer

https://doi.org/10.18632/oncotarget.26113

Karina Brüstle,  and Bettina Heidecker
33440-33440
Correction  |  PDF

Correction: Comparative oncology DNA sequencing of canine T cell lymphoma via human hotspot panel

Correction: Comparative oncology DNA sequencing of canine T cell lymphoma via human hotspot panel

https://doi.org/10.18632/oncotarget.26114

J. Tyson McDonald, Athena Kritharis, Afshin Beheshti, Monika Pilichowska, Kristine Burgess, Luisel Ricks-Santi, Elizabeth McNiel, Cheryl A. London, Dashnamoorthy Ravi,  and Andrew M. Evens
33441-33441
Correction  |  PDF


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