Oncotarget

Vol 9, No 66

August 24, 2018

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About The Cover

The cover for issue 66 of Oncotarget features Figure 4, "RNA sequencing of PDX tumors," by Jayatilaka, et al.

Table of Contents

News

Selecting suitable chemotherapies for PD-1/PD-L1 blockade to optimize the tumor immune microenvironment

Selecting suitable chemotherapies for PD-1/PD-L1 blockade to optimize the tumor immune microenvironment

https://doi.org/10.18632/oncotarget.26028

Shohei Koyama, Izumi Nagatomo, Takashi Kijima,  and Atsushi Kumanogoh
32552-32553
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Editorial

Balance deficits in long-term pediatric ALL survivors

Balance deficits in long-term pediatric ALL survivors

https://doi.org/10.18632/oncotarget.25967

Mitra Varedi, Kirsten K. Ness,  and Raymond F. McKenna
32554-32555
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Research Papers

Tumor cell density regulates matrix metalloproteinases for enhanced migration

Tumor cell density regulates matrix metalloproteinases for enhanced migration

https://doi.org/10.18632/oncotarget.25863

Hasini Jayatilaka, Fatima G. Umanzor, Vishwesh Shah, Tomer Meirson, Gabriella Russo, Bartholomew Starich, Pranay Tyle, Jerry S.H. Lee, Shyam Khatau, Hava Gil-Henn,  and Denis Wirtz
32556-32569
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Circulating tumor DNA as a marker of treatment response in BRAF V600E mutated non-melanoma solid tumors

Circulating tumor DNA as a marker of treatment response in BRAF V600E mutated non-melanoma solid tumors

https://doi.org/10.18632/oncotarget.25948

Lise Barlebo Ahlborn, Ida Viller Tuxen, Florent Mouliere, Savvas Kinalis, Ane Y. Schmidt, Kristoffer Staal Rohrberg, Eric Santoni-Rugiu, Finn Cilius Nielsen, Ulrik Lassen, Christina Westmose Yde, Olga Oestrup,  and Morten Mau-Sorensen
32570-32579
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Chromatin remodeling protein HELLS is upregulated by inactivation of the RB-E2F pathway and is nonessential for osteosarcoma tumorigenesis

Chromatin remodeling protein HELLS is upregulated by inactivation of the RB-E2F pathway and is nonessential for osteosarcoma tumorigenesis

https://doi.org/10.18632/oncotarget.25953

Stephanie C. Wu,  and Claudia A. Benavente
32580-32592
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Alendronate-induced disruption of actin cytoskeleton and inhibition of migration/invasion are associated with cofilin downregulation in PC-3 prostate cancer cells

Alendronate-induced disruption of actin cytoskeleton and inhibition of migration/invasion are associated with cofilin downregulation in PC-3 prostate cancer cells

https://doi.org/10.18632/oncotarget.25961

Sanna S. Virtanen, Tamiko Ishizu, Jouko A. Sandholm, Eliisa Löyttyniemi, H. Kalervo Väänänen, Johanna M. Tuomela,  and Pirkko L. Härkönen
32593-32608
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Hematopoietic lineage cell-specific protein 1 (HS1), a hidden player in migration, invasion, and tumor formation, is over-expressed in ovarian carcinoma cells

Hematopoietic lineage cell-specific protein 1 (HS1), a hidden player in migration, invasion, and tumor formation, is over-expressed in ovarian carcinoma cells

https://doi.org/10.18632/oncotarget.25975

Yoshihiro Koya, Wenting Liu, Yoshihiko Yamakita, Takeshi Senga, Kiyosumi Shibata, Mamoru Yamashita, Akihiro Nawa, Fumitaka Kikkawa,  and Hiroaki Kajiyama
32609-32623
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Quantitative screening of serum protein biomarkers by reverse phase protein arrays

Quantitative screening of serum protein biomarkers by reverse phase protein arrays

https://doi.org/10.18632/oncotarget.25976

Zhizhou Kuang, Ruochun Huang, Zhimin Yang, Zhiqiang Lv, Xinyan Chen, Fuping Xu, Yu-Hua Yi, Jian Wu,  and Ruo-Pan Huang
32624-32641
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Mutational analysis of uterine cervical cancer that survived multiple rounds of radiotherapy

Mutational analysis of uterine cervical cancer that survived multiple rounds of radiotherapy

https://doi.org/10.18632/oncotarget.25982

Endang Nuryadi, Yasushi Sasaki, Yoshihiko Hagiwara, Tiara Bunga Mayang Permata, Hiro Sato, Shuichiro Komatsu, Yuya Yoshimoto, Kazutoshi Murata, Ken Ando, Nobuteru Kubo, Noriyuki Okonogi, Yosuke Takakusagi, Akiko Adachi, Mototaro Iwanaga, Keisuke Tsuchida, Tomoaki Tamaki, Shin-ei Noda, Yuka Hirota, Atsushi Shibata, Tatsuya Ohno, Takashi Tokino, Takahiro Oike,  and Takashi Nakano
32642-32652
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The frequency of promoter DNA hypermethylation is decreased in colorectal neoplasms of familial adenomatous polyposis

The frequency of promoter DNA hypermethylation is decreased in colorectal neoplasms of familial adenomatous polyposis

https://doi.org/10.18632/oncotarget.25987

Kiyoko Takane, Masaki Fukuyo, Keisuke Matsusaka, Satoshi Ota, Bahityar Rahmutulla, Kazuyuki Matsushita, Hideaki Miyauchi, Yukio Nakatani, Hisahiro Matsubara,  and Atsushi Kaneda
32653-32666
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Involvement of GLUT1-mediated glucose transport and metabolism in gefitinib resistance of non-small-cell lung cancer cells

Involvement of GLUT1-mediated glucose transport and metabolism in gefitinib resistance of non-small-cell lung cancer cells

https://doi.org/10.18632/oncotarget.25994

Shuhei Suzuki, Masashi Okada, Hiroyuki Takeda, Kenta Kuramoto, Tomomi Sanomachi, Keita Togashi, Shizuka Seino, Masahiro Yamamoto, Takashi Yoshioka,  and Chifumi Kitanaka
32667-32679
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Absence of correlation between radiation-induced CD8 T-lymphocyte apoptosis and sequelae in patients with prostate cancer accidentally overexposed to radiation

Absence of correlation between radiation-induced CD8 T-lymphocyte apoptosis and sequelae in patients with prostate cancer accidentally overexposed to radiation

https://doi.org/10.18632/oncotarget.26001

Guillaume Vogin, Jean-Louis Merlin, Alexandra Rousseau, Didier Peiffert, Alexandre Harlé, Marie Husson, Labib El Hajj, Mihai Levitchi, Tabassome Simon,  and Jean-Marc Simon
32680-32689
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A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal transducer and activator of transcription 3 (STAT3)

A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal transducer and activator of transcription 3 (STAT3)

https://doi.org/10.18632/oncotarget.26013

Po-Chang Shih, Yiwen Yang, Gary N. Parkinson, Andrew Wilderspin,  and Geoffrey Wells
32690-32701
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dual targeting of HSP70 does not induce the heat shock response and synergistically reduces cell viability in muscle invasive bladder cancer

Dual targeting of HSP70 does not induce the heat shock response and synergistically reduces cell viability in muscle invasive bladder cancer

https://doi.org/10.18632/oncotarget.26021

Thomas Prince, Andrew Ackerman, Alice Cavanaugh, Brielle Schreiter, Brendon Juengst, Chaylen Andolino, John Danella, Mitch Chernin,  and Heinric Williams
32702-32717
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A patient-derived orthotopic xenograft model enabling human high-grade urothelial cell carcinoma of the bladder tumor implantation, growth, angiogenesis, and metastasis

A patient-derived orthotopic xenograft model enabling human high-grade urothelial cell carcinoma of the bladder tumor implantation, growth, angiogenesis, and metastasis

https://doi.org/10.18632/oncotarget.26024

Jessie Gills, Ravan Moret, Xin Zhang, John Nelson, Grace Maresh, Linh Hellmers, Daniel Canter, M’Liss Hudson, Shams Halat, Marc Matrana, Michael P. Marino, Jakob Reiser, Maureen Shuh, Eric Laborde, Maria Latsis, Sunil Talwar, Stephen Bardot,  and Li Li
32718-32729
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Corrections

Correction: Mechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivo

Correction: Mechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivo

https://doi.org/10.18632/oncotarget.26065

Hong Yang, Liuyuan Guan, Shun Li, Ying Jiang, Niya Xiong, Li Li, Chunhui Wu, Hongjuan Zeng,  and Yiyao Liu
32730-32730
Correction  |  PDF

Correction: SEL1L SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy

Correction: SEL1L SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy

https://doi.org/10.18632/oncotarget.26066

Marta Mellai, Monica Cattaneo, Alessandra Maria Storaci, Laura Annovazzi, Paola Cassoni, Antonio Melcarne, Pasquale De Blasio, Davide Schiffer,  and Ida Biunno
32731-32731
Correction  |  PDF


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