Oncotarget

Vol 9, No 60

August 3, 2018

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About The Cover

The cover for issue 60 of Oncotarget features Figure 8, "Modeling of palbociclib resistance in KRAS-mutant NSCLC cells and effects of MAP kinase pathway inhibition," by Haines, et al.

Table of Contents

News

Chk-mate on resistance to kinase inhibitors

Chk-mate on resistance to kinase inhibitors

https://doi.org/10.18632/oncotarget.25802

Paul Shapiro
31560-31561
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CSCs: regenerating optimism for osteosarcoma treatment

CSCs: regenerating optimism for osteosarcoma treatment

https://doi.org/10.18632/oncotarget.25820

Adam S. Levin
31562-31563
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The path to « the Golden Age » for the treatment of metastatic renal cell carcinoma

The path to « the Golden Age » for the treatment of metastatic renal cell carcinoma

https://doi.org/10.18632/oncotarget.25832

Gilles Pagès
31564-31565
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Editorial

Are membranes non-apoptotic compartments for apoptotic caspases?

Are membranes non-apoptotic compartments for apoptotic caspases?

https://doi.org/10.18632/oncotarget.25796

Andreas Bergmann
31566-31567
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Copy number of latent viruses, oncogenicity, and the microcompetition model

Copy number of latent viruses, oncogenicity, and the microcompetition model

https://doi.org/10.18632/oncotarget.25804

Hanan Polansky,  and Hava Schwab
31568-31569
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AMPK activates DAPK2 to promote autophagy

AMPK activates DAPK2 to promote autophagy

https://doi.org/10.18632/oncotarget.25842

Ruth Shiloh,  and Adi Kimchi
31570-31571
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Priority Research Papers

Palbociclib resistance confers dependence on an FGFR-MAP kinase-mTOR-driven pathway in KRAS-mutant non-small cell lung cancer

Palbociclib resistance confers dependence on an FGFR-MAP kinase-mTOR-driven pathway in KRAS-mutant non-small cell lung cancer

https://doi.org/10.18632/oncotarget.25803

Eric Haines, Ting Chen, Naveen Kommajosyula, Zhao Chen, Grit S. Herter-Sprie, Liam Cornell, Kwok-Kin Wong,  and Geoffrey I. Shapiro
31572-31589
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers

Resistance to complement activation, cell membrane hypersialylation and relapses in chronic lymphocytic leukemia patients treated with rituximab and chemotherapy

Resistance to complement activation, cell membrane hypersialylation and relapses in chronic lymphocytic leukemia patients treated with rituximab and chemotherapy

https://doi.org/10.18632/oncotarget.25657

Anne Bordron, Cristina Bagacean, Audrey Mohr, Adrian Tempescul, Boutahar Bendaoud, Stéphanie Deshayes, Florence Dalbies, Caroline Buors, Hussam Saad, Christian Berthou, Jacques-Olivier Pers,  and Yves Renaudineau
31590-31605
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Genomic alterations at the basis of treatment resistance in metastatic breast cancer: clinical applications

Genomic alterations at the basis of treatment resistance in metastatic breast cancer: clinical applications

https://doi.org/10.18632/oncotarget.25810

Angela Toss, Federico Piacentini, Laura Cortesi, Lucia Artuso, Isabella Bernardis, Sandra Parenti, Elena Tenedini, Guido Ficarra, Antonino Maiorana, Anna Iannone, Claudia Omarini, Luca Moscetti, Massimo Cristofanilli, Massimo Federico,  and Enrico Tagliafico
31606-31619
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A comprehensive evaluation of Hippo pathway silencing in sarcomas

A comprehensive evaluation of Hippo pathway silencing in sarcomas

https://doi.org/10.18632/oncotarget.25824

Nicole M. Merritt, Colleen A. Fullenkamp, Sarah L. Hall, Qining Qian, Chandni Desai, Jon Thomason, Allyn M. Lambertz, Adam J. Dupuy, Benjamin Darbro,  and Munir R. Tanas
31620-31636
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FGFR1/FOXM1 pathway: a key regulator of glioblastoma stem cells radioresistance and a prognosis biomarker

FGFR1/FOXM1 pathway: a key regulator of glioblastoma stem cells radioresistance and a prognosis biomarker

https://doi.org/10.18632/oncotarget.25827

Valérie Gouazé-Andersson, Marie-Julie Ghérardi, Anthony Lemarié, Julia Gilhodes, Vincent Lubrano, Florent Arnauduc, Elizabeth Cohen-Jonathan Moyal,  and Christine Toulas
31637-31649
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of distress screening algorithm for psycho-oncological needs in neurosurgical patients

Impact of distress screening algorithm for psycho-oncological needs in neurosurgical patients

https://doi.org/10.18632/oncotarget.25833

Marion Rapp, Stephanie Schipmann, Kira Hoffmann, Rainer Wiewrodt, Hans-Jakob Steiger, Marcel Kamp, Walter Stummer, Dorothee Wiewrodt,  and Michael Sabel
31650-31663
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Inborn-like errors of metabolism are determinants of breast cancer risk, clinical response and survival: a study of human biochemical individuality

Inborn-like errors of metabolism are determinants of breast cancer risk, clinical response and survival: a study of human biochemical individuality

https://doi.org/10.18632/oncotarget.25839

Ismael da Silva, Rene da Costa Vieira, Carolina Stella, Edson Loturco, André Lopes Carvalho, Carlos Veo, Cristovam Neto, Sandra M. Silva, Paulo D'Amora, Marcia Salzgeber, Delcio Matos, Celso R. Silva, Jose R. Oliveira, Iara Rabelo, Patricia Yamakawa, Rui Maciel, Rosa Biscolla, Maria Chiamolera, Renato Fraietta, Felipe Reis, Marcelo Mori, Dirce Marchioni, Antonio Carioca, Gustavo Maciel, Renato Tomioka, Edmund Baracat, Clovis Silva, Celso Granato, Ricardo Diaz, Bruno Scarpellini, Daniel Egle, Heidi Fiegl, Irmgard Himmel, Christina Troi,  and Robert Nagourney
31664-31681
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Paradoxical counteraction by imatinib against cell death in myeloid progenitor 32D cells expressing p210BCR-ABL

Paradoxical counteraction by imatinib against cell death in myeloid progenitor 32D cells expressing p210BCR-ABL

https://doi.org/10.18632/oncotarget.25849

Morichika Takita, Fujiko Tsukahara, Taishi Mishima, Katsuaki Ieguchi, Masayuki Yamada, Hiroaki Honda,  and Yoshiro Maru
31682-31696
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Suppression of SOCS3 enhances TRAIL-induced cell growth inhibition through the upregulation of DR4 expression in renal cell carcinoma cells

Suppression of SOCS3 enhances TRAIL-induced cell growth inhibition through the upregulation of DR4 expression in renal cell carcinoma cells

https://doi.org/10.18632/oncotarget.25851

Michihiro Yabe, Kei Ishibashi, Akifumi Onagi, Ryo Tanji, Ruriko Honda-Takinami, Tomoyuki Koguchi, Kanako Matsuoka, Seiji Hoshi, Junya Hata, Masao Kataoka, Soichiro Ogawa, Hiroyuki Hiraki, Nobuhiro Haga,  and Yoshiyuki Kojima
31697-31708
Abstract  |  PDF  |  HTML  |  Order a Reprint

A Phase Ib, open-label, dose-finding study of alpelisib in combination with paclitaxel in patients with advanced solid tumors

A Phase Ib, open-label, dose-finding study of alpelisib in combination with paclitaxel in patients with advanced solid tumors

https://doi.org/10.18632/oncotarget.25854

Jordi Rodon, Giuseppe Curigliano, Jean-Pierre Delord, Wael Harb, Analia Azaro, Yu Han, Celine Wilke, Valerie Donnet, Dalila Sellami,  and Thaddeus Beck
31709-31718
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity

DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity

https://doi.org/10.18632/oncotarget.25859

Jianfeng Li, David Svilar, Steven McClellan, Jung-Hyun Kim, Eun-Young Erin Ahn, Conchita Vens, David M. Wilson III,  and Robert W. Sobol
31719-31743
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Advantages of systematic trunk SPECT/CT to planar bone scan (PBS) in more than 300 patients with breast or prostate cancer

Advantages of systematic trunk SPECT/CT to planar bone scan (PBS) in more than 300 patients with breast or prostate cancer

https://doi.org/10.18632/oncotarget.25860

Vincent Fleury, Ludovic Ferrer, Mathilde Colombié, Daniéla Rusu, Maëlle Le Thiec, Françoise Kraeber-Bodéré, Loïc Campion,  and Caroline Rousseau
31744-31752
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A novel fatty acid-binding protein 5-estrogen-related receptor α signaling pathway promotes cell growth and energy metabolism in prostate cancer cells

A novel fatty acid-binding protein 5-estrogen-related receptor α signaling pathway promotes cell growth and energy metabolism in prostate cancer cells

https://doi.org/10.18632/oncotarget.25878

Shogo Senga, Koichiro Kawaguchi, Narumi Kobayashi, Akira Ando,  and Hiroshi Fujii
31753-31770
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Liver metastasis of pancreatic cancer: the hepatic microenvironment impacts differentiation and self-renewal capacity of pancreatic ductal epithelial cells

Liver metastasis of pancreatic cancer: the hepatic microenvironment impacts differentiation and self-renewal capacity of pancreatic ductal epithelial cells

https://doi.org/10.18632/oncotarget.25884

Hendrike Knaack, Lennart Lenk, Lisa-Marie Philipp, Lauritz Miarka, Sascha Rahn, Fabrice Viol, Charlotte Hauser, Jan-Hendrik Egberts, Jan-Paul Gundlach, Olga Will, Sanjay Tiwari, Wolfgang Mikulits, Udo Schumacher, Jan G. Hengstler,  and Susanne Sebens
31771-31786
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Corrections

Correction: Halofuginone inhibits radiotherapy-induced epithelial-mesenchymal transition in lung cancer

Correction: Halofuginone inhibits radiotherapy-induced epithelial-mesenchymal transition in lung cancer

https://doi.org/10.18632/oncotarget.25958

Yang Chen, Weishuai Liu, Peng Wang, Hailing Hou, Ningbo Liu, Linlin Gong, Youyou Wang, Kai Ji, Lujun Zhao,  and Ping Wang
31787-31787
Correction  |  PDF

Correction: Colon cancer-induced interleukin-35 inhibits betacatenin- mediated pro-oncogenic activity

Correction: Colon cancer-induced interleukin-35 inhibits betacatenin- mediated pro-oncogenic activity

https://doi.org/10.18632/oncotarget.25959

Yueqiang Jiang, Yanling Ma, RuiChao Li,  and JianHai Sun
31788-31788
Correction  |  PDF

Correction: Characterization of HBV integration patterns and timing in liver cancer and HBV-infected livers

Correction: Characterization of HBV integration patterns and timing in liver cancer and HBV-infected livers

https://doi.org/10.18632/oncotarget.25960

Mayuko Furuta, Hiroko Tanaka, Yuichi Shiraishi, Takuro Uchida, Michio Imamura, Akihiro Fujimoto, Masahi Fujita, Aya Sasaki-Oku, Kazuhiro Maejima, Kaoru Nakano, Yoshiiku Kawakami, Koji Arihiro, Hiroshi Aikata, Masaki Ueno, Shinya Hayami, Shun-Ichi Ariizumi, Masakazu Yamamoto, Kunihito Gotoh, Hideki Ohdan, Hiroki Yamaue, Satoru Miyano, Kazuaki Chayama,  and Hidewaki Nakagawa
31789-31789
Correction  |  PDF


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