Oncotarget

Vol 9, No 57

July 24, 2018

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About The Cover

The cover for issue 57 of Oncotarget features Figure 1A, "Schematic representation of our systematic approach developed to identify effective compounds and biological vulnerabilities in EwS.," by Tsafou, et al.

 

Table of Contents

News

Modification of the tumour microenvironment via exosomal shedding of sphingosine 1-phosphate receptor 2 by breast cancer cells

Modification of the tumour microenvironment via exosomal shedding of sphingosine 1-phosphate receptor 2 by breast cancer cells

https://doi.org/10.18632/oncotarget.25793

Stuart M. Pitson,  and Jason A. Powell
30938-30939
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Editorial

The vulnerability of RB loss in breast cancer: Targeting a void in cell cycle control

The vulnerability of RB loss in breast cancer: Targeting a void in cell cycle control

https://doi.org/10.18632/oncotarget.25797

Erik S. Knudsen,  and Eldad Zacksenhaus
30940-30941
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Expedited approval of cancer drugs without randomized controlled trials: Too good to be true?

Expedited approval of cancer drugs without randomized controlled trials: Too good to be true?

https://doi.org/10.18632/oncotarget.25799

Daniel Shepshelovich,  and Eitan Amir
30942-30943
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Metastability, an emerging concept governing BOK-mediated apoptosis initiation

Metastability, an emerging concept governing BOK-mediated apoptosis initiation

https://doi.org/10.18632/oncotarget.25801

Tudor Moldoveanu,  and Janet H. Zheng
30944-30945
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Research Papers

Patient derived renal cell carcinoma xenografts exhibit distinct sensitivity patterns in response to antiangiogenic therapy and constitute a suitable tool for biomarker development

Patient derived renal cell carcinoma xenografts exhibit distinct sensitivity patterns in response to antiangiogenic therapy and constitute a suitable tool for biomarker development

https://doi.org/10.18632/oncotarget.25697

Julia Schueler, Kerstin Klingner, Daniel Bug, Caren Zoeller, Armin Maier, Meng Dong, Kerstin Willecke, Anne-Lise Peille, Eva Steiner, Manuel Landesfeind, John A. Copland, Gabrielle M. Siegers, Axel Haferkamp, Katharina Boehm, Igor Tsaur,  and Meike Schneider
30946-30961
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Cell-specific plasticity associated with integrative memory of triple sensory signals in the barrel cortex

Cell-specific plasticity associated with integrative memory of triple sensory signals in the barrel cortex

https://doi.org/10.18632/oncotarget.25740

Jing Feng, Wei Lu, Guang-Yan Wang, Zhao-Ming Zhu, Yan Sun, Kaixin Du,  and Jin-Hui Wang
30962-30978
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Increased expression of the thyroid hormone nuclear receptor TRα1 characterizes intestinal tumors with high Wnt activity

Increased expression of the thyroid hormone nuclear receptor TRα1 characterizes intestinal tumors with high Wnt activity

https://doi.org/10.18632/oncotarget.25741

Joel Uchuya-Castillo, Nicolas Aznar, Carla Frau, Pierre Martinez, Clementine Le Nevé, Laetitia Marisa, Luiz O.F. Penalva, Pierre Laurent-Puig, Alain Puisieux, Jean-Yves Scoazec, Jacques Samarut, Stephane Ansieau,  and Michelina Plateroti
30979-30996
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Impact of cell fusion in myeloma marrow microenvironment on tumor progression

Impact of cell fusion in myeloma marrow microenvironment on tumor progression

https://doi.org/10.18632/oncotarget.25742

Ziyan Wang, Yuqing Yuan, Liying Zhang, Zhou Min, Dongming Zhou, Sun Yu, Panjun Wang, Songguang Ju, Li Jun,  and Jinxiang Fu
30997-31006
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Comparative proteomics of soluble factors secreted by human breast adipose tissue from tumor and normal breast

Comparative proteomics of soluble factors secreted by human breast adipose tissue from tumor and normal breast

https://doi.org/10.18632/oncotarget.25749

Sabrina Johanna Fletcher, María Belén Hapon, Eduardo A. Callegari, María Luján Crosbie, Natalia Santiso, Anabela Ursino, Alicia Rita Amato, Alberto Gutiérrez, Paula Alejandra Sacca, Rubén Dreszman, Adriana Pérez, Rubén Walter Carón, Juan Carlos Calvo,  and Virginia Pistone-Creydt
31007-31017
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Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers

https://doi.org/10.18632/oncotarget.25760

Kalliopi Tsafou, Anna Maria Katschnig, Branka Radic-Sarikas, Cornelia Noëlle Mutz, Kristiina Iljin, Raphaela Schwentner, Maximilian O. Kauer, Karin Mühlbacher, Dave N.T. Aryee, David Westergaard, Saija Haapa-Paananen, Vidal Fey, Giulio Superti-Furga, Jeffrey Toretsky, Søren Brunak,  and Heinrich Kovar
31018-31031
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High O-linked N-acetylglucosamine transferase expression predicts poor survival in patients with early stage lung adenocarcinoma

High O-linked N-acetylglucosamine transferase expression predicts poor survival in patients with early stage lung adenocarcinoma

https://doi.org/10.18632/oncotarget.25772

Yi-Cheng Lin, Chia-Hung Lin, Yi-Chen Yeh, Hsiang-Ling Ho, Yu-Chung Wu, Mei-Yu Chen,  and Teh-Ying Chou
31032-31044
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Spatial and temporal proteome dynamics of glioma cells during oncolytic adenovirus Delta-24-RGD infection

Spatial and temporal proteome dynamics of glioma cells during oncolytic adenovirus Delta-24-RGD infection

https://doi.org/10.18632/oncotarget.25774

Andrea González-Morales, Aintzane Zabaleta, Elizabeth Guruceaga, Marta M. Alonso, Marc García-Moure, Joaquín Fernández-Irigoyen,  and Enrique Santamaría
31045-31065
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A method for treatment monitoring using circulating tumour DNA in cancer patients without targetable mutations

A method for treatment monitoring using circulating tumour DNA in cancer patients without targetable mutations

https://doi.org/10.18632/oncotarget.25779

Christina Demuth, Anne Winther-Larsen, Anne Tranberg Madsen, Peter Meldgaard,  and Boe Sandahl Sorensen
31066-31076
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STAT3 is constitutively activated in chronic active Epstein-Barr virus infection and can be a therapeutic target

STAT3 is constitutively activated in chronic active Epstein-Barr virus infection and can be a therapeutic target

https://doi.org/10.18632/oncotarget.25780

Erika Onozawa, Haruna Shibayama, Honami Takada, Ken-Ichi Imadome, Sho Aoki, Mayumi Yoshimori, Norio Shimizu, Shigeyoshi Fujiwara, Takatoshi Koyama, Osamu Miura,  and Ayako Arai
31077-31089
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

C-X-C Motif Ligand 1 (CXCL1) from melanoma cells down-regulates the invasion of their metastatic melanoma cells

C-X-C Motif Ligand 1 (CXCL1) from melanoma cells down-regulates the invasion of their metastatic melanoma cells

https://doi.org/10.18632/oncotarget.25783

Takaharu Hatano, Masakazu Yashiro, Heishiro Fujikawa,  and Hisashi Motomura
31090-31097
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Stim and Orai mediate constitutive Ca2+ entry and control endoplasmic reticulum Ca2+ refilling in primary cultures of colorectal carcinoma cells

Stim and Orai mediate constitutive Ca2+ entry and control endoplasmic reticulum Ca2+ refilling in primary cultures of colorectal carcinoma cells

https://doi.org/10.18632/oncotarget.25785

Estella Zuccolo, Umberto Laforenza, Federica Ferulli, Giorgia Pellavio, Giorgia Scarpellino, Matteo Tanzi, Ilaria Turin, Pawan Faris, Angela Lucariello, Marcello Maestri, Dlzar Ali Kheder, Germano Guerra, Paolo Pedrazzoli, Daniela Montagna,  and Francesco Moccia
31098-31119
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Meta-Analysis

Lung cancer susceptibility from GSTM1 deletion and air pollution with smoking status: a meta-prediction of worldwide populations

Lung cancer susceptibility from GSTM1 deletion and air pollution with smoking status: a meta-prediction of worldwide populations

https://doi.org/10.18632/oncotarget.25693

Pojui Yu, Joyce D. Kusuma, Maria Aurora R. Suarez,  and Shyang-Yun Pamela Koong Shiao
31120-31132
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Screening for distress in patients with intracranial tumors during the first 6 months after diagnosis using self-reporting instruments and an expert rating scale (the basic documentation for psychooncology short form – PO-Bado SF)

Screening for distress in patients with intracranial tumors during the first 6 months after diagnosis using self-reporting instruments and an expert rating scale (the basic documentation for psychooncology short form – PO-Bado SF)

https://doi.org/10.18632/oncotarget.25763

Mirjam Renovanz, Helena Tsakmaklis, Sari Soebianto, Isabell Neppel, Minou Nadji-Ohl, Manfred Beutel, Andreas Werner, Florian Ringel,  and Anne-Katrin Hickmann
31133-31145
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Reviews

Helicobacter pylori associated factors in the development of gastric cancer with special reference to the early-onset subtype

Helicobacter pylori associated factors in the development of gastric cancer with special reference to the early-onset subtype

https://doi.org/10.18632/oncotarget.25757

Małgorzata Pucułek, Julita Machlowska, Ryszard Wierzbicki, Jacek Baj, Ryszard Maciejewski,  and Robert Sitarz
31146-31162
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