Oncotarget

Vol 9, No 51

July 3, 2018

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About The Cover

The cover for issue 51 of Oncotarget features Figure 5, "CAD and POLD2 association with chemotherapy response in bladder cancer patients," by Givechian, et al.

Table of Contents

Research Papers

Polymorphisms in DNA mismatch repair pathway genes predict toxicity and response to cisplatin chemoradiation in head and neck squamous cell carcinoma patients

Polymorphisms in DNA mismatch repair pathway genes predict toxicity and response to cisplatin chemoradiation in head and neck squamous cell carcinoma patients

https://doi.org/10.18632/oncotarget.25268

Guilherme Augusto Silva Nogueira, Ericka Francislaine Dias Costa, Leisa Lopes-Aguiar, Tathiane Regine Penna Lima, Marília Berlofa Visacri, Eder Carvalho Pincinato, Gustavo Jacob Lourenço, Luciane Calonga, Fernanda Viviane Mariano, Albina Messias de Almeida Milani Altemani, João Maurício Carrasco Altemani, Patrícia Moriel, Carlos Takahiro Chone, Celso Dario Ramos,  and Carmen Silvia Passos Lima
29538-29547
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Genetic landscape of long noncoding RNA (lncRNAs) in glioblastoma: identification of complex lncRNA regulatory networks and clinically relevant lncRNAs in glioblastoma

Genetic landscape of long noncoding RNA (lncRNAs) in glioblastoma: identification of complex lncRNA regulatory networks and clinically relevant lncRNAs in glioblastoma

https://doi.org/10.18632/oncotarget.25434

Yashna Paul, Sannu Thomas, Vikas Patil, Naveen Kumar, Baisakhi Mondal, Alangar S. Hegde, Arimappamagan Arivazhagan, Vani Santosh, Kulandaivelu Mahalingam,  and Kumaravel Somasundaram
29548-29564
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Phosphatidylinositol 3-kinase p110δ expression in Merkel cell carcinoma

Phosphatidylinositol 3-kinase p110δ expression in Merkel cell carcinoma

https://doi.org/10.18632/oncotarget.25619

Emil Chteinberg, Dorit Rennspiess, Ryan Sambo, Samantha Tauchmann, Nicole W.J. Kelleners-Smeets, Véronique Winnepenninckx, Ernst-Jan Speel, Anna Kordelia Kurz, Martin Zenke,  and Axel zur Hausen
29565-29573
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Fibrosis in metastatic lymph nodes is clinically correlated to poor prognosis in colorectal cancer

Fibrosis in metastatic lymph nodes is clinically correlated to poor prognosis in colorectal cancer

https://doi.org/10.18632/oncotarget.25636

Daiji Ikuta, Toru Miyake, Tomoharu Shimizu, Hiromichi Sonoda, Ken-Ichi Mukaisho, Aya Tokuda, Tomoyuki Ueki, Hiroyuki Sugihara,  and Masaji Tani
29574-29586
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Inhibition of mTOR downregulates expression of DNA repair proteins and is highly efficient against BRCA2-mutated breast cancer in combination to PARP inhibition

Inhibition of mTOR downregulates expression of DNA repair proteins and is highly efficient against BRCA2-mutated breast cancer in combination to PARP inhibition

https://doi.org/10.18632/oncotarget.25640

Rania El Botty, Florence Coussy, Rana Hatem, Franck Assayag, Sophie Chateau-Joubert, Jean-Luc Servely, Sophie Leboucher, Charles Fouillade, Sophie Vacher, Bérengère Ouine, Aurélie Cartier, Leanne de Koning, Paul Cottu, Ivan Bièche,  and Elisabetta Marangoni
29587-29600
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LMO1 functions as an oncogene by regulating TTK expression and correlates with neuroendocrine differentiation of lung cancer

LMO1 functions as an oncogene by regulating TTK expression and correlates with neuroendocrine differentiation of lung cancer

https://doi.org/10.18632/oncotarget.25642

Liqin Du, Zhenze Zhao, Milind Suraokar, Spencer S. Shelton, Xiuye Ma, Tzu-Hung Hsiao, John D. Minna, Ignacio Wistuba,  and Alexander Pertsemlidis
29601-29618
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PCP4/PEP19 upregulates aromatase gene expression via CYP19A1 promoter I.1 in human breast cancer SK-BR-3 cells

PCP4/PEP19 upregulates aromatase gene expression via CYP19A1 promoter I.1 in human breast cancer SK-BR-3 cells

https://doi.org/10.18632/oncotarget.25651

Kie Honjo, Taiji Hamada, Takuya Yoshimura, Seiya Yokoyama, Sohsuke Yamada, Yan-Qin Tan, Lai K. Leung, Norifumi Nakamura, Yasuyo Ohi, Michiyo Higashi,  and Akihide Tanimoto
29619-29633
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TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A

https://doi.org/10.18632/oncotarget.25659

Sin Ying Cheung, Matthias Henrot, Mohammad Al-Saad, Matthias Baumann, Heiko Muller, Anke Unger, Hussein N. Rubaiy, Ilka Mathar, Klaus Dinkel, Peter Nussbaumer, Bert Klebl, Marc Freichel, Baptiste Rode, Sebastian Trainor, Steven J. Clapcote, Mathias Christmann, Herbert Waldmann, Syed Khawar Abbas, David J. Beech,  and Naveen S. Vasudev
29634-29643
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Polymorphism of regulatory region of APEH gene (c.-521G>C, rs4855883) as a relevant predictive factor for radiotherapy induced oral mucositis and overall survival in head neck cancer patients

Polymorphism of regulatory region of APEH gene (c.-521G>C, rs4855883) as a relevant predictive factor for radiotherapy induced oral mucositis and overall survival in head neck cancer patients

https://doi.org/10.18632/oncotarget.25662

Anna Brzozowska, Radosław Mlak, Iwona Homa-Mlak, Paweł Gołębiowski, Marcin Mazurek, Marzanna Ciesielka,  and Teresa Małecka-Massalska
29644-29653
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RET fusions observed in lung and colorectal cancers are sensitive to ponatinib

RET fusions observed in lung and colorectal cancers are sensitive to ponatinib

https://doi.org/10.18632/oncotarget.25664

Joseph M. Gozgit, Tzu-Hsiu Chen, Youngchul Song, Scott Wardwell, Frank Wang, Jie Cai, Henry Li, Henrik Edgren, Victor M. Rivera,  and Justin Pritchard
29654-29664
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KLF5 controls glutathione metabolism to suppress p190-BCR-ABL+ B-cell lymphoblastic leukemia

KLF5 controls glutathione metabolism to suppress p190-BCR-ABL+ B-cell lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.25667

Cuiping Zhang, Angelo D'Alessandro, Ashley M. Wellendorf, Fatima Mohmoud, Juana Serrano-Lopez, John P. Perentesis, Kakajan Komurov, Gabriela Alexe, Kimberly Stegmaier, Jeffrey A. Whitsett, H. Leighton Grimes,  and Jose A. Cancelas
29665-29679
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A CARP-1 functional mimetic compound is synergistic with BRAF-targeting in non-small cell lung cancers

A CARP-1 functional mimetic compound is synergistic with BRAF-targeting in non-small cell lung cancers

https://doi.org/10.18632/oncotarget.25671

Vino T. Cheriyan, Hashem Alsaab, Sreeja Sekhar, Jaganathan Venkatesh, Arindam Mondal, Imran Vhora, Samaresh Sau, Magesh Muthu, Lisa A. Polin, Edi Levi, Gerold Bepler, Arun K. Iyer, Mandip Singh,  and Arun K. Rishi
29680-29697
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Suppression of stress induction of the 78-kilodalton glucose regulated protein (GRP78) in cancer by IT-139, an anti-tumor ruthenium small molecule inhibitor

Suppression of stress induction of the 78-kilodalton glucose regulated protein (GRP78) in cancer by IT-139, an anti-tumor ruthenium small molecule inhibitor

https://doi.org/10.18632/oncotarget.25679

Suzanne J. Bakewell, Daisy F. Rangel, Dat P. Ha, Jyothi Sethuraman, Richard Crouse, Emma Hadley, Tara L. Costich, Xingliang Zhou, Peter Nichols,  and Amy S. Lee
29698-29714
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TIE2-expressing monocytes and M2-polarized macrophages impact survival and correlate with angiogenesis in adenocarcinoma of the pancreas

TIE2-expressing monocytes and M2-polarized macrophages impact survival and correlate with angiogenesis in adenocarcinoma of the pancreas

https://doi.org/10.18632/oncotarget.25690

Georgi Atanasov, Charlotte Pötner, Gabriela Aust, Katrin Schierle, Corinna Dietel, Christian Benzing, Felix Krenzien, Michael Bartels, Uwe Eichfeld, Moritz Schmelzle, Marcus Bahra, Andreas Pascher,  and Georg Wiltberger
29715-29726
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MGMT inhibition in ER positive breast cancer leads to CDC2, TOP2A, AURKB, CDC20, KIF20A, Cyclin A2, Cyclin B2, Cyclin D1, ERα and Survivin inhibition and enhances response to temozolomide

MGMT inhibition in ER positive breast cancer leads to CDC2, TOP2A, AURKB, CDC20, KIF20A, Cyclin A2, Cyclin B2, Cyclin D1, ERα and Survivin inhibition and enhances response to temozolomide

https://doi.org/10.18632/oncotarget.25696

George C. Bobustuc, Amin B. Kassam, Richard A. Rovin, Sheila Jeudy, Joshua S. Smith, Beth Isley, Maharaj Singh, Ameya Paranjpe, Kalkunte S. Srivenugopal,  and Santhi D. Konduri
29727-29742
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CAD/POLD2 gene expression is associated with poor overall survival and chemoresistance in bladder urothelial carcinoma

CAD/POLD2 gene expression is associated with poor overall survival and chemoresistance in bladder urothelial carcinoma

https://doi.org/10.18632/oncotarget.25701

Kevin B. Givechian, Chad Garner, Hermes Garban, Shahrooz Rabizadeh,  and Patrick Soon-Shiong
29743-29752
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MYC-related microRNAs signatures in non-Hodgkin B-cell lymphomas and their relationships with core cellular pathways

MYC-related microRNAs signatures in non-Hodgkin B-cell lymphomas and their relationships with core cellular pathways

https://doi.org/10.18632/oncotarget.25707

Giorgio Malpeli, Stefano Barbi, Gabriele Tosadori, Corinna Greco, Simonetta Zupo, Serena Pedron, Matteo Brunelli, Anna Bertolaso, Maria Teresa Scupoli, Mauro Krampera, Paul Takam Kamga, Carlo Maria Croce, George Adrian Calin, Aldo Scarpa,  and Alberto Zamò
29753-29771
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TRAF3IP2, a novel therapeutic target in glioblastoma multiforme

TRAF3IP2, a novel therapeutic target in glioblastoma multiforme

https://doi.org/10.18632/oncotarget.25710

Eckhard U. Alt, Zahra Barabadi, Andreas Pfnür, Joana E. Ochoa, Fatemeh Daneshimehr, Lea M. Lang, Dong Lin, Stephen E. Braun, Bysani Chandrasekar,  and Reza Izadpanah
29772-29788
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GSTP1 rs1695 is associated with both hematological toxicity and prognosis of ovarian cancer treated with paclitaxel plus carboplatin combination chemotherapy: a comprehensive analysis using targeted resequencing of 100 pharmacogenes

GSTP1 rs1695 is associated with both hematological toxicity and prognosis of ovarian cancer treated with paclitaxel plus carboplatin combination chemotherapy: a comprehensive analysis using targeted resequencing of 100 pharmacogenes

https://doi.org/10.18632/oncotarget.25712

Tomoko Yoshihama, Koya Fukunaga, Akira Hirasawa, Hiroyuki Nomura, Tomoko Akahane, Fumio Kataoka, Wataru Yamagami, Daisuke Aoki,  and Taisei Mushiroda
29789-29800
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Meta-Analysis

Second-line chemotherapy for the treatment of metastatic pancreatic cancer after first-line gemcitabine-based chemotherapy: a network meta-analysis

Second-line chemotherapy for the treatment of metastatic pancreatic cancer after first-line gemcitabine-based chemotherapy: a network meta-analysis

https://doi.org/10.18632/oncotarget.25639

Chiara Citterio, Michela Baccini, Elena Orlandi, Camilla Di Nunzio,  and Luigi Cavanna
29801-29809
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Clinical Research Papers

Postoperative empyema following lung cancer surgery

Postoperative empyema following lung cancer surgery

https://doi.org/10.18632/oncotarget.25629

Noriyuki Matsutani, Katsuo Yoshiya, Masayuki Chida, Hirozo Sakaguchi, Takuma Kikkawa, Hiroki Fukuda, Nobumasa Takahashi, Noriyoshi Sawabata, Hirotoshi Horio, Nobuhiko Seki,  and Masafumi Kawamura
29810-29819
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Systematic literature review of IL-6 as a biomarker or treatment target in patients with gastric, bile duct, pancreatic and colorectal cancer

Systematic literature review of IL-6 as a biomarker or treatment target in patients with gastric, bile duct, pancreatic and colorectal cancer

https://doi.org/10.18632/oncotarget.25661

Noomi Vainer, Christian Dehlendorff,  and Julia S. Johansen
29820-29841
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Corrections

Correction: Implications of PI3K/AKT inhibition on REST protein stability and neuroendocrine phenotype acquisition in prostate cancer cells

Correction: Implications of PI3K/AKT inhibition on REST protein stability and neuroendocrine phenotype acquisition in prostate cancer cells

https://doi.org/10.18632/oncotarget.25759

Ruiqi Chen, Yinan Li, Ralph Buttyan,  and Xuesen Dong
29842-29842
Correction  |  PDF


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