Oncotarget

Vol 9, No 50

June 29, 2018

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About The Cover

The cover for issue 50 of Oncotarget features Figure 4, "Correlation analysis between TLR4 and IL-6 / IL-10 mRNA expression in HCC tumors in all HCC patients and in obese HCC patients," by Nguyen, et al.

Table of Contents

Research Papers

The TGFα-EGFR-Akt signaling axis plays a role in enhancing proinflammatory chemokines in triple-negative breast cancer cells

The TGFα-EGFR-Akt signaling axis plays a role in enhancing proinflammatory chemokines in triple-negative breast cancer cells

https://doi.org/10.18632/oncotarget.25389

Rosa Mistica C. Ignacio, Carla R. Gibbs, Eun-Sook Lee,  and Deok-Soo Son
29286-29303
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Concomitant attenuation of HMG-CoA reductase expression potentiates the cancer cell growth-inhibitory effect of statins and expands their efficacy in tumor cells with epithelial characteristics

Concomitant attenuation of HMG-CoA reductase expression potentiates the cancer cell growth-inhibitory effect of statins and expands their efficacy in tumor cells with epithelial characteristics

https://doi.org/10.18632/oncotarget.25448

Takuro Ishikawa, Yoshinao Z. Hosaka, Colin Beckwitt, Alan Wells, Zoltán N. Oltvai,  and Katsuhiko Warita
29304-29315
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Region-specific alteration of histone modification by LSD1 inhibitor conjugated with pyrrole-imidazole polyamide

Region-specific alteration of histone modification by LSD1 inhibitor conjugated with pyrrole-imidazole polyamide

https://doi.org/10.18632/oncotarget.25451

Kokiladevi Alagarswamy, Ken-Ichi Shinohara, Shihori Takayanagi, Masaki Fukuyo, Atsushi Okabe, Bahityar Rahmutulla, Natsumi Yoda, Rui Qin, Naoki Shiga, Masahiro Sugiura, Hiroaki Sato, Kazuko Kita, Takayoshi Suzuki, Tetsuhiro Nemoto,  and Atsushi Kaneda
29316-29335
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Frequent CLDN18-ARHGAP fusion in highly metastatic diffuse-type gastric cancer with relatively early onset

Frequent CLDN18-ARHGAP fusion in highly metastatic diffuse-type gastric cancer with relatively early onset

https://doi.org/10.18632/oncotarget.25464

Atsushi Tanaka, Shumpei Ishikawa, Tetsuo Ushiku, Sho Yamazawa, Hiroto Katoh, Akimasa Hayashi, Akiko Kunita,  and Masashi Fukayama
29336-29350
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Comparison of the prognostic impact and combination of preoperative inflammation-based and/or nutritional markers in patients with stage II gastric cancer

Comparison of the prognostic impact and combination of preoperative inflammation-based and/or nutritional markers in patients with stage II gastric cancer

https://doi.org/10.18632/oncotarget.25486

Takahiro Toyokawa, Kazuya Muguruma, Tatsuro Tamura, Katsunobu Sakurai, Ryosuke Amano, Naoshi Kubo, Hiroaki Tanaka, Masakazu Yashiro, Kosei Hirakawa,  and Masaichi Ohira
29351-29364
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Neutral metalloaminopeptidases APN and MetAP2 as newly discovered anticancer molecular targets of actinomycin D and its simple analogs

Neutral metalloaminopeptidases APN and MetAP2 as newly discovered anticancer molecular targets of actinomycin D and its simple analogs

https://doi.org/10.18632/oncotarget.25532

Ewelina Węglarz-Tomczak, Michał Talma, Mirosław Giurg, Hans V. Westerhoff, Robert Janowski,  and Artur Mucha
29365-29378
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Numb has distinct function in lung adenocarcinoma and squamous cell carcinoma

Numb has distinct function in lung adenocarcinoma and squamous cell carcinoma

https://doi.org/10.18632/oncotarget.25585

Hajime Kikuchi, Jun Sakakibara-Konishi, Megumi Furuta, Eiki Kikuchi, Junko Kikuchi, Satoshi Oizumi, Yasuhiro Hida, Kichizo Kaga, Ichiro Kinoshita, Hirotoshi Dosaka-Akita,  and Masaharu Nishimura
29379-29391
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FcγRI expression on macrophages is required for antibody-mediated tumor protection by cytomegalovirus-based vaccines

FcγRI expression on macrophages is required for antibody-mediated tumor protection by cytomegalovirus-based vaccines

https://doi.org/10.18632/oncotarget.25630

Hreinn Benonisson, Heng Sheng Sow, Cor Breukel, Jill W.C. Claassens, Conny Brouwers, Margot M. Linssen, Anke Redeker, Marieke F. Fransen, Thorbald van Hall, Ferry Ossendorp, Ramon Arens,  and Sjef Verbeek
29392-29402
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Circulating tumor cells mirror bone metastatic phenotype in prostate cancer

Circulating tumor cells mirror bone metastatic phenotype in prostate cancer

https://doi.org/10.18632/oncotarget.25634

Andreas Josefsson, Karin Larsson, Marianne Månsson, Jens Björkman, Eva Rohlova, Daniel Åhs, Helena Brisby, Jan-Erik Damber,  and Karin Welén
29403-29413
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CRISPR/Cas9 nickase mediated targeting of urokinase receptor gene inhibits neuroblastoma cell proliferation

CRISPR/Cas9 nickase mediated targeting of urokinase receptor gene inhibits neuroblastoma cell proliferation

https://doi.org/10.18632/oncotarget.25647

Karina D. Rysenkova, Ekaterina V. Semina, Maxim N. Karagyaur, Anna A. Shmakova, Daniyar T. Dyikanov, Petr A. Vasiluev, Yury P. Rubtsov, Kseniya A. Rubina,  and Vsevolod A. Tkachuk
29414-29430
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Use of a novel camelid-inspired human antibody demonstrates the importance of MMP-14 to cancer stem cell function in the metastatic process

Use of a novel camelid-inspired human antibody demonstrates the importance of MMP-14 to cancer stem cell function in the metastatic process

https://doi.org/10.18632/oncotarget.25654

Kuan-Hui E. Chen, Chuan Chen, Tyler Lopez, Kelly C. Radecki, Karissa Bustamante, Mary Y. Lorenson, Xin Ge,  and Ameae M. Walker
29431-29444
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MACROD2 expression predicts response to 5-FU-based chemotherapy in stage III colon cancer

MACROD2 expression predicts response to 5-FU-based chemotherapy in stage III colon cancer

https://doi.org/10.18632/oncotarget.25655

Evert van den Broek, Sjoerd H. den Uil, Veerle M.H. Coupé, Pien M. Delis-van Diemen, Anne S. Bolijn, Herman Bril, Hein B.A.C. Stockmann, Nicole C.T. van Grieken, Gerrit A. Meijer,  and Remond J.A. Fijneman
29445-29452
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The sphingosine 1-phosphate receptor 2 is shed in exosomes from breast cancer cells and is N-terminally processed to a short constitutively active form that promotes extracellular signal regulated kinase activation and DNA synthesis in fibroblasts

The sphingosine 1-phosphate receptor 2 is shed in exosomes from breast cancer cells and is N-terminally processed to a short constitutively active form that promotes extracellular signal regulated kinase activation and DNA synthesis in fibroblasts

https://doi.org/10.18632/oncotarget.25658

Ashref El Buri, David R. Adams, Douglas Smith, Rothwelle J. Tate, Margaret Mullin, Susan Pyne,  and Nigel J. Pyne
29453-29467
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The calcium channel proteins ORAI3 and STIM1 mediate TGF-β induced Snai1 expression

The calcium channel proteins ORAI3 and STIM1 mediate TGF-β induced Snai1 expression

https://doi.org/10.18632/oncotarget.25672

Atrayee Bhattacharya, Janani Kumar, Kole Hermanson, Yuyang Sun, Humaira Qureshi, Danielle Perley, Adam Scheidegger, Brij B. Singh,  and Archana Dhasarathy
29468-29483
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Bone mineral density and microarchitecture linkages with micro- and macro-vascular impairments at the hand in systemic sclerosis: an HRpQCT study

Bone mineral density and microarchitecture linkages with micro- and macro-vascular impairments at the hand in systemic sclerosis: an HRpQCT study

https://doi.org/10.18632/oncotarget.25681

Lucie Atlan, Nada Ibrahim-Nasser, Antoine Valery, Carole Bazzi, François Rollin, Guido Bens, Mathilde Marot, Eric Estève,  and Eric Lespessailles
29484-29494
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Toll-like receptor 4: a target for chemoprevention of hepatocellular carcinoma in obesity and steatohepatitis

Toll-like receptor 4: a target for chemoprevention of hepatocellular carcinoma in obesity and steatohepatitis

https://doi.org/10.18632/oncotarget.25685

Jennifer Nguyen, Jingjing Jiao, Kristin Smoot, Gordon P. Watt, Chen Zhao, Xingzhi Song, Heather L. Stevenson, Joseph B. McCormick, Susan P. Fisher-Hoch, Jianhua Zhang, P. Andrew Futreal,  and Laura Beretta
29495-29507
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The relationship of CDK18 expression in breast cancer to clinicopathological parameters and therapeutic response

The relationship of CDK18 expression in breast cancer to clinicopathological parameters and therapeutic response

https://doi.org/10.18632/oncotarget.25686

Giancarlo Barone, Arvind Arora, Anil Ganesh, Tarek Abdel-Fatah, Paul Moseley, Reem Ali, Stephen YT Chan, Constantinos Savva, Kristina Schiavone, Natasha Carmell, Katie N. Myers, Emad A. Rakha, Srinivasan Madhusudan,  and Spencer J. Collis
29508-29524
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Clinical Research Papers

Clinical significance of repeat rebiopsy in detecting the EGFR T790M secondary mutation in patients with non-small cell lung cancer

Clinical significance of repeat rebiopsy in detecting the EGFR T790M secondary mutation in patients with non-small cell lung cancer

https://doi.org/10.18632/oncotarget.25705

Eiki Ichihara, Katsuyuki Hotta, Toshio Kubo, Tsukasa Higashionna, Kiichiro Ninomiya, Kadoaki Ohashi, Masahiro Tabata, Yoshinobu Maeda,  and Katsuyuki Kiura
29525-29531
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Case Reports

Treatment of EGFR mutation–positive non–small cell lung cancer complicated by Trousseau syndrome with gefitinib followed by osimertinib: a case report

Treatment of EGFR mutation–positive non–small cell lung cancer complicated by Trousseau syndrome with gefitinib followed by osimertinib: a case report

https://doi.org/10.18632/oncotarget.25687

Yoshikane Nonagase, Masayuki Takeda, Kaoru Tanaka, Hidetoshi Hayashi, Tsutomu Iwasa,  and Kazuhiko Nakagawa
29532-29535
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Corrections

Correction: Beneficial bacteria inhibit cachexia

Correction: Beneficial bacteria inhibit cachexia

https://doi.org/10.18632/oncotarget.25750

Bernard J. Varian, Sravya Gourishetti, Theofilos Poutahidis, Jessica R. Lakritz, Tatiana Levkovich, Caitlin Kwok, Konstantinos Teliousis, Yassin M. Ibrahim, Sheyla Mirabal,  and Susan E. Erdman
29536-29536
Correction  |  PDF

Correction: Circulating and tumor-associated caspase-4: a novel diagnostic and prognostic biomarker for non-small cell lung cancer

Correction: Circulating and tumor-associated caspase-4: a novel diagnostic and prognostic biomarker for non-small cell lung cancer

https://doi.org/10.18632/oncotarget.25751

Michela Terlizzi, Chiara Colarusso, Ilaria De Rosa, Nicolina De Rosa, Pasquale Somma, Carlo Curcio, Alessandro Sanduzzi, Pietro Micheli, Antonio Molino, Antonello Saccomanno, Rosario Salvi, Rita P. Aquino, Aldo Pinto,  and Rosalinda Sorrentino
29537-29537
Correction  |  PDF


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