Oncotarget

Vol 9, No 41

May 29, 2018

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About The Cover

The cover for issue 41 of Oncotarget features Figure 5, "Variant allele frequencies for associated selected genomic alterations," by Tarlock, et al.

Table of Contents

Research Papers

KRAS, NRAS and BRAF mutations detected by next generation sequencing, and differential clinical outcome in metastatic colorectal cancer (MCRC) patients treated with first line FIr-B/FOx adding bevacizumab (BEV) to triplet chemotherapy

KRAS, NRAS and BRAF mutations detected by next generation sequencing, and differential clinical outcome in metastatic colorectal cancer (MCRC) patients treated with first line FIr-B/FOx adding bevacizumab (BEV) to triplet chemotherapy

https://doi.org/10.18632/oncotarget.25180

Gemma Bruera, Francesco Pepe, Umberto Malapelle, Pasquale Pisapia, Antonella Dal Mas, Daniela Di Giacomo, Giuseppe Calvisi, Giancarlo Troncone,  and Enrico Ricevuto
26279-26290
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Prostate stem cell antigen mRNA in blood is a predictor of survival after radical prostatectomy in patients with high-risk prostate cancer

Prostate stem cell antigen mRNA in blood is a predictor of survival after radical prostatectomy in patients with high-risk prostate cancer

https://doi.org/10.18632/oncotarget.25207

Yoon Seok Suh, Jae Young Joung, Sung Han Kim, Jeong Eun Kim, Moon Kyung Choi, Weon Seo Park, Sang-Jin Lee, Ho Kyung Seo, Jinsoo Chung,  and Kang Hyun Lee
26291-26298
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Steviol, a natural product inhibits proliferation of the gastrointestinal cancer cells intensively

Steviol, a natural product inhibits proliferation of the gastrointestinal cancer cells intensively

https://doi.org/10.18632/oncotarget.25233

Junming Chen, Yongmei Xia, Xiaochen Sui, Qingrui Peng, Tongtong Zhang, Jian Li,  and Jue Zhang
26299-26308
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Deregulation of calcium homeostasis in Bcr-Abl-dependent chronic myeloid leukemia

Deregulation of calcium homeostasis in Bcr-Abl-dependent chronic myeloid leukemia

https://doi.org/10.18632/oncotarget.25241

Hélène Cabanas, Thomas Harnois, Christophe Magaud, Laëtitia Cousin, Bruno Constantin, Nicolas Bourmeyster,  and Nadine Déliot
26309-26327
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Histone deacetylase inhibitor trichostatin A sensitises cisplatin-resistant ovarian cancer cells to oncolytic adenovirus

Histone deacetylase inhibitor trichostatin A sensitises cisplatin-resistant ovarian cancer cells to oncolytic adenovirus

https://doi.org/10.18632/oncotarget.25242

Sarah L. Hulin-Curtis, James A. Davies, Rachel Jones, Emma Hudson, Louise Hanna, John D. Chester,  and Alan L. Parker
26328-26341
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PSMD4 is a novel therapeutic target in chemoresistant colorectal cancer activated by cytoplasmic localization of Nrf2

PSMD4 is a novel therapeutic target in chemoresistant colorectal cancer activated by cytoplasmic localization of Nrf2

https://doi.org/10.18632/oncotarget.25254

Ya-Min Cheng, Po-Lin Lin, De-Wei Wu, Lee Wang, Chi-Chou Huang,  and Huei Lee
26342-26352
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Potent anti-leukemic activity of a specific cyclin-dependent kinase 9 inhibitor in mouse models of chronic lymphocytic leukemia

Potent anti-leukemic activity of a specific cyclin-dependent kinase 9 inhibitor in mouse models of chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.25293

Joachim R. Göthert, Roze Imsak, Michael Möllmann, Stefanie Kesper, Maria Göbel, Ulrich Dührsen, Arne Scholz, Ulrich Lücking, Matthias Baumann, Anke Unger, Carsten Schultz-Fademrecht, Bert Klebl, Jan Eickhoff, Axel Choidas,  and Jan Dürig
26353-26369
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Oleanolic acid induces p53-dependent apoptosis via the ERK/JNK/AKT pathway in cancer cell lines in prostatic cancer xenografts in mice

Oleanolic acid induces p53-dependent apoptosis via the ERK/JNK/AKT pathway in cancer cell lines in prostatic cancer xenografts in mice

https://doi.org/10.18632/oncotarget.25316

Gyeong-Ji Kim, Hyeon-Ju Jo, Kwon-Jai Lee, Jeong Woo Choi,  and Jeung Hee An
26370-26386
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Differential miRNA expression profiling reveals miR-205-3p to be a potential radiosensitizer for low- dose ionizing radiation in DLD-1 cells

Differential miRNA expression profiling reveals miR-205-3p to be a potential radiosensitizer for low- dose ionizing radiation in DLD-1 cells

https://doi.org/10.18632/oncotarget.25405

Rodrigo Andaur, Julio C. Tapia, José Moreno, Leopoldo Soto, Ricardo Armisen,  and Katherine Marcelain
26387-26405
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Triple negative breast cancer subtypes and pathologic complete response rate to neoadjuvant chemotherapy

Triple negative breast cancer subtypes and pathologic complete response rate to neoadjuvant chemotherapy

https://doi.org/10.18632/oncotarget.25413

Angela Santonja, Alfonso Sánchez-Muñoz, Ana Lluch, Maria Rosario Chica-Parrado, Joan Albanell, José Ignacio Chacón, Silvia Antolín, José Manuel Jerez, Juan de la Haba, Vanessa de Luque, Cristina Elisabeth Fernández-De Sousa, Luis Vicioso, Yéssica Plata, César Luis Ramírez-Tortosa, Martina Álvarez, Casilda Llácer, Irene Zarcos-Pedrinaci, Eva Carrasco, Rosalía Caballero, Miguel Martín,  and Emilio Alba
26406-26416
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Distinct age-associated molecular profiles in acute myeloid leukemia defined by comprehensive clinical genomic profiling

Distinct age-associated molecular profiles in acute myeloid leukemia defined by comprehensive clinical genomic profiling

https://doi.org/10.18632/oncotarget.25443

Katherine Tarlock, Shan Zhong, Yuting He, Rhonda Ries, Eric Severson, Mark Bailey, Samantha Morley, Sohail Balasubramanian, Rachel Erlich, Doron Lipson, Geoff A. Otto, Jo-Anne Vergillo, E. Anders Kolb, Jeffrey S. Ross, Tariq Mughal, Philip J. Stephens, Vincent Miller, Soheil Meshinchi,  and Jie He
26417-26430
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Direct molecular dissection of tumor parenchyma from tumor stroma in tumor xenograft using mass spectrometry-based glycoproteomics

Direct molecular dissection of tumor parenchyma from tumor stroma in tumor xenograft using mass spectrometry-based glycoproteomics

https://doi.org/10.18632/oncotarget.25449

Xiaoying Ye, Brian T. Luke, Bih-Rong Wei, Jan A. Kaczmarczyk, Jadranka Loncarek, Jennifer E. Dwyer, Donald J. Johann, Richard G. Saul, Dwight V. Nissley, Frank McCormick, Gordon R. Whiteley,  and Josip Blonder
26431-26452
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Biomarkers for the risk of thrombosis in pancreatic adenocarcinoma are related to cancer process

Biomarkers for the risk of thrombosis in pancreatic adenocarcinoma are related to cancer process

https://doi.org/10.18632/oncotarget.25458

Dorothée Faille, Marie-Charlotte Bourrienne, Emmanuelle de Raucourt, Luc de Chaisemartin, Vanessa Granger, Romaric Lacroix, Laurence Panicot-Dubois, Pascal Hammel, Philippe Lévy, Philippe Ruszniewski, Nadine Ajzenberg,  and Vinciane Rebours
26453-26465
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Folic acid–conjugated mesoporous silica particles as nanocarriers of natural prodrugs for cancer targeting and antioxidant action

Folic acid–conjugated mesoporous silica particles as nanocarriers of natural prodrugs for cancer targeting and antioxidant action

https://doi.org/10.18632/oncotarget.25470

Khaled AbouAitah, Anna Swiderska-Sroda, Ahmed A. Farghali, Jacek Wojnarowicz, Agata Stefanek, Stanislaw Gierlotka, Agnieszka Opalinska, Abdou K. Allayeh, Tomasz Ciach,  and Witold Lojkowski
26466-26490
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Hitting two oncogenic machineries in cancer cells: cooperative effects of the multi-kinase inhibitor ponatinib and the BET bromodomain blockers JQ1 or dBET1 on human carcinoma cells

Hitting two oncogenic machineries in cancer cells: cooperative effects of the multi-kinase inhibitor ponatinib and the BET bromodomain blockers JQ1 or dBET1 on human carcinoma cells

https://doi.org/10.18632/oncotarget.25474

Karin Bauer, Daniela Berger, Christoph C. Zielinski, Peter Valent,  and Thomas W. Grunt
26491-26506
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Biologic canine and human intervertebral disc repair by notochordal cell-derived matrix: from bench towards bedside

Biologic canine and human intervertebral disc repair by notochordal cell-derived matrix: from bench towards bedside

https://doi.org/10.18632/oncotarget.25476

Frances C. Bach, Anna R. Tellegen, Martijn Beukers, Alberto Miranda-Bedate, Michelle Teunissen, Willem A.M. de Jong, Stefan A.H. de Vries, Laura B. Creemers, Karin Benz, Björn P. Meij, Keita Ito,  and Marianna A. Tryfonidou
26507-26526
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Synergistic antitumor activity by combining trastuzumab with retinoic acid in HER2 positive human breast cancer cells

Synergistic antitumor activity by combining trastuzumab with retinoic acid in HER2 positive human breast cancer cells

https://doi.org/10.18632/oncotarget.25480

Fiorella Vanderhoeven, Analía Lourdes Redondo, Ana Laura Martinez, Laura María Vargas-Roig, Angel Matias Sanchez,  and Marina Inés Flamini
26527-26542
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Characterization and diagnostic application of genomic NPM-ALK fusion sequences in anaplastic large-cell lymphoma

Characterization and diagnostic application of genomic NPM-ALK fusion sequences in anaplastic large-cell lymphoma

https://doi.org/10.18632/oncotarget.25489

Manuela Krumbholz, Wilhelm Woessmann, Jakob Zierk, David Seniuk, Paolo Ceppi, Martin Zimmermann, Vijay Kumar Singh, Markus Metzler,  and Christine Damm-Welk
26543-26555
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Hypoxia-targeted gold nanorods for cancer photothermal therapy

Hypoxia-targeted gold nanorods for cancer photothermal therapy

https://doi.org/10.18632/oncotarget.25492

Yuan Chen, Xiaomei Bian, Maureen Aliru, Amit A. Deorukhkar, Oscar Ekpenyong, Su Liang, Jyothy John, Jing Ma, Xiuqing Gao, Jon Schwartz, Pankaj Singh, Yuanqing Ye, Sunil Krishnan,  and Huan Xie
26556-26571
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A novel role of metal response element binding transcription factor 2 at the Hox gene cluster in the regulation of H3K27me3 by polycomb repressive complex 2

A novel role of metal response element binding transcription factor 2 at the Hox gene cluster in the regulation of H3K27me3 by polycomb repressive complex 2

https://doi.org/10.18632/oncotarget.25505

Abdul Aziz Khan, Seok-Jin Ham, Le Ngoc Yen, Haeng Lim Lee, Jounghyun Huh, Hyeongrin Jeon, Myoung Hee Kim,  and Tae-Young Roh
26572-26585
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Reviews

Prostaglandins in the pathogenesis of kidney diseases

Prostaglandins in the pathogenesis of kidney diseases

https://doi.org/10.18632/oncotarget.25005

Yuanyuan Li, Weiwei Xia, Fei Zhao, Zhaoying Wen, Aihua Zhang, Songming Huang, Zhanjun Jia,  and Yue Zhang
26586-26602
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