Oncotarget

Vol 9, No 28

April 13, 2018

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About The Cover

The cover for issue 28 of Oncotarget features Figure 2, "Association of PSES with tumor stage in patients with EEC," from Du, et al.


Table of Contents

Editorial: Autophagy and Cell Death

ER stress sensing mechanism: Putting off the brake on UPR transducers

ER stress sensing mechanism: Putting off the brake on UPR transducers

https://doi.org/10.18632/oncotarget.25114

Diego Rojas-Rivera, Diego A. Rodriguez, Denisse Sepulveda,  and Claudio Hetz
19461-19462
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Research Perspectives

Main implications related to the switch to BRCA1/2 tumor testing in ovarian cancer patients: a proposal of a consensus

Main implications related to the switch to BRCA1/2 tumor testing in ovarian cancer patients: a proposal of a consensus

https://doi.org/10.18632/oncotarget.24728

Ettore Capoluongo, Giovanni Scambia,  and Jean-Marc Nabholtz
19463-19468
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Research Papers: Immunology

Identification of neoepitopes recognized by tumor-infiltrating lymphocytes (TILs) from patients with glioma

Identification of neoepitopes recognized by tumor-infiltrating lymphocytes (TILs) from patients with glioma

https://doi.org/10.18632/oncotarget.24955

Davide Valentini, Martin Rao, Qingda Meng, Anna von Landenberg, Jiri Bartek Jr, Georges Sinclair, Georgia Paraschoudi, Elke Jäger, Inti Harvey-Peredo, Ernest Dodoo,  and Markus Maeurer
19469-19480
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Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin

Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin

https://doi.org/10.18632/oncotarget.24603

Anders Woetmann, Morten Alhede, Sally Dabelsteen, Thomas Bjarnsholt, Morten Rybtke, Claudia Nastasi, Thorbjørn Krejsgaard, Mads Hald Andersen, Charlotte M. Bonefeld, Carsten Geisler, Michael Givskov,  and Niels Odum
19481-19489
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Research Papers

Macrophages induce “budding” in aggressive human colon cancer subtypes by protease-mediated disruption of tight junctions

Macrophages induce “budding” in aggressive human colon cancer subtypes by protease-mediated disruption of tight junctions

https://doi.org/10.18632/oncotarget.24626

Kari Trumpi, Nicola Frenkel, Timo Peters, Nicoline M. Korthagen, Jennifer M.J. Jongen, Daniëlle Raats, Helma van Grevenstein, Yara Backes, Leon M. Moons, Miangela M. Lacle, Jan Koster, Danny Zwijnenburg, Inne H.M. Borel Rinkes,  and Onno Kranenburg
19490-19507
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gamma-Klotho exhibits multiple roles in tumor growth of human bladder cancer

Gamma-Klotho exhibits multiple roles in tumor growth of human bladder cancer

https://doi.org/10.18632/oncotarget.24628

Shunta Hori, Makito Miyake, Yoshihiro Tatsumi, Yosuke Morizawa, Yasushi Nakai, Sayuri Onishi, Kenta Onishi, Kota Iida, Daisuke Gotoh, Nobumichi Tanaka,  and Kiyohide Fujimoto
19508-19524
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Aurora B prevents premature removal of spindle assembly checkpoint proteins from the kinetochore: A key role for Aurora B in mitosis

Aurora B prevents premature removal of spindle assembly checkpoint proteins from the kinetochore: A key role for Aurora B in mitosis

https://doi.org/10.18632/oncotarget.10657

Mark D. Gurden, Simon J. Anderhub, Amir Faisal,  and Spiros Linardopoulos
19525-19542
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Total body irradiation and iron chelation treatment are associated with pancreatic injury following pediatric hematopoietic stem cell transplantation

Total body irradiation and iron chelation treatment are associated with pancreatic injury following pediatric hematopoietic stem cell transplantation

https://doi.org/10.18632/oncotarget.24646

Natalia Maximova, Massimo Gregori, Roberto Simeone, Aurelio Sonzogni, Davide Zanon, Giulia Boz,  and Lorenzo D’Antiga
19543-19554
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TP53 and OSBPL10 alterations in diffuse large B-cell lymphoma: prognostic markers identified via exome analysis of cases with extreme prognosis

TP53 and OSBPL10 alterations in diffuse large B-cell lymphoma: prognostic markers identified via exome analysis of cases with extreme prognosis

https://doi.org/10.18632/oncotarget.24656

Akito Dobashi, Yuki Togashi, Norio Tanaka, Masahiro Yokoyama, Naoko Tsuyama, Satoko Baba, Seiichi Mori, Kiyohiko Hatake, Toshiharu Yamaguchi, Tetsuo Noda,  and Kengo Takeuchi
19555-19568
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In vitro study on role of σB protein in avian reovirus pathogenesis

In vitro study on role of σB protein in avian reovirus pathogenesis

https://doi.org/10.18632/oncotarget.24668

Manas R. Praharaj, Aditya P. Sahoo, Tapan K.S. Chauhan, Ravi Kumar Gandham, Shikha Saxena, Ravi K. Agarwal, Kuldeep Dhama, Bina Mishra, Asok K. Marriappan, Ashok K. Tiwari, Puroshottam Prasad Goswami, Bishnu Prasad Mishra,  and Deepak Kumar
19569-19583
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Anti-cachectic effect of Antrodia cinnamomea extract in lung tumor-bearing mice under chemotherapy

Anti-cachectic effect of Antrodia cinnamomea extract in lung tumor-bearing mice under chemotherapy

https://doi.org/10.18632/oncotarget.24680

Meng-Chuan Chen, Wen-Lin Hsu,  and Tz-Chong Chou
19584-19596
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Blockage of the mevalonate pathway overcomes the apoptotic resistance to MEK inhibitors with suppressing the activation of Akt in cancer cells

Blockage of the mevalonate pathway overcomes the apoptotic resistance to MEK inhibitors with suppressing the activation of Akt in cancer cells

https://doi.org/10.18632/oncotarget.24696

Mahiro Iizuka-Ohashi, Motoki Watanabe, Mamiko Sukeno, Mie Morita, Ngoc Thi Hong Hoang, Takahiro Kuchimaru, Shinae Kizaka-Kondoh, Yoshihiro Sowa, Koichi Sakaguchi, Tetsuya Taguchi,  and Toshiyuki Sakai
19597-19612
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Indolent lymphoma with composite histology and simultaneous transformation at initial diagnosis exhibit clinical features similar to de novo diffuse large B-cell lymphoma

Indolent lymphoma with composite histology and simultaneous transformation at initial diagnosis exhibit clinical features similar to de novo diffuse large B-cell lymphoma

https://doi.org/10.18632/oncotarget.24701

Hanno Witte, Harald Biersack, Svenja Kopelke, Dirk Rades, Hartmut Merz, Veronica Bernard, Hendrik Lehnert,  and Niklas Gebauer
19613-19622
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated seminal plasma estradiol and epigenetic inactivation of ESR1 and ESR2 is associated with CP/CPPS

Elevated seminal plasma estradiol and epigenetic inactivation of ESR1 and ESR2 is associated with CP/CPPS

https://doi.org/10.18632/oncotarget.24714

Nils Nesheim, Stuart Ellem, Temuujin Dansranjavin, Christina Hagenkötter, Elena Berg, Rupert Schambeck, Hans-Christian Schuppe, Adrian Pilatz, Gail Risbridger, Wolfgang Weidner, Florian Wagenlehner,  and Undraga Schagdarsurengin
19623-19639
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gendermetrics of cancer research: results from a global analysis on prostate cancer

Gendermetrics of cancer research: results from a global analysis on prostate cancer

https://doi.org/10.18632/oncotarget.24716

Michael H.K. Bendels, Alecsandru M. Costrut, Norman Schöffel, Dörthe Brüggmann,  and David A. Groneberg
19640-19649
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

KIR2DL2 combined with HLA-C1 confers risk of hepatitis C virus-related hepatocellular carcinoma in younger patients

KIR2DL2 combined with HLA-C1 confers risk of hepatitis C virus-related hepatocellular carcinoma in younger patients

https://doi.org/10.18632/oncotarget.24752

Hiromi Saito, Takeji Umemura, Satoru Joshita, Tomoo Yamazaki, Naoyuki Fujimori, Takefumi Kimura, Michiharu Komatsu, Akihiro Matsumoto, Eiji Tanaka,  and Masao Ota
19650-19661
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Co-expression and prognostic significance of the HER family members, EGFRvIII, c-MET, CD44 in patients with ovarian cancer

Co-expression and prognostic significance of the HER family members, EGFRvIII, c-MET, CD44 in patients with ovarian cancer

https://doi.org/10.18632/oncotarget.24791

Soozana Puvanenthiran, Sharadah Essapen, Ben Haagsma, Izhar Bagwan, Margaret Green, Said Abdullah Khelwatty, Alan Seddon,  and Helmout Modjtahedi
19662-19674
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Genetic rearrangements, hotspot mutations, and microRNA expression in the progression of metastatic adenoid cystic carcinoma of the salivary gland

Genetic rearrangements, hotspot mutations, and microRNA expression in the progression of metastatic adenoid cystic carcinoma of the salivary gland

https://doi.org/10.18632/oncotarget.24800

Simon Andreasen, Tina Klitmøller Agander, Kristine Bjørndal, Daiva Erentaite, Steffen Heegaard, Stine R. Larsen, Linea Cecilie Melchior, Qihua Tan, Benedicte Parm Ulhøi, Irene Wessel,  and Preben Homøe
19675-19687
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Deletion of plasma Phospholipid Transfer Protein (PLTP) increases microglial phagocytosis and reduces cerebral amyloid-β deposition in the J20 mouse model of Alzheimer's disease

Deletion of plasma Phospholipid Transfer Protein (PLTP) increases microglial phagocytosis and reduces cerebral amyloid-β deposition in the J20 mouse model of Alzheimer's disease

https://doi.org/10.18632/oncotarget.24802

Marine Mansuy, Stella Baille, Geoffrey Canet, Amélie Borie, Catherine Cohen-Solal, Michel Vignes, Véronique Perrier, Nathalie Chevallier, Naig Le Guern, Valérie Deckert, Laurent Lagrost, Laurent Givalois,  and Catherine Desrumaux
19688-19703
Abstract  |  PDF  |  HTML  |  Order a Reprint

Predicting high-risk endometrioid carcinomas using proteins

Predicting high-risk endometrioid carcinomas using proteins

https://doi.org/10.18632/oncotarget.24803

Di Du, Wencai Ma, Melinda S. Yates, Tao Chen, Karen H. Lu, Yiling Lu, John N. Weinstein, Russell R. Broaddus, Gordon B. Mills,  and Yuexin Liu
19704-19715
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Constraint based modeling of metabolism allows finding metabolic cancer hallmarks and identifying personalized therapeutic windows

Constraint based modeling of metabolism allows finding metabolic cancer hallmarks and identifying personalized therapeutic windows

https://doi.org/10.18632/oncotarget.24805

Sergio Bordel
19716-19729
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia

Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia

https://doi.org/10.18632/oncotarget.24808

Frida Danielsson, Erik Fasterius, Devin Sullivan, Linnea Hases, Kemal Sanli, Cheng Zhang, Adil Mardinoglu, Cristina Al-Khalili, Mikael Huss, Mathias Uhlén, Cecilia Williams,  and Emma Lundberg
19730-19744
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long-term predictive models of risk factors for early chronic kidney disease: a longitudinal study

Long-term predictive models of risk factors for early chronic kidney disease: a longitudinal study

https://doi.org/10.18632/oncotarget.24820

Wen-Chih Wu, Po-Chien Hsieh, Fu-Kang Hu, Jen-Chun Kuan, Chi-Ming Chu, Chien-An Sun, Tsan Yang, Sui-Lung Su,  and Yu-Ching Chou
19745-19752
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mouse genetic background influences whether HrasG12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma

Mouse genetic background influences whether HrasG12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma

https://doi.org/10.18632/oncotarget.24831

Laura P. Brandt, Joachim Albers, Tomas Hejhal, Svende Pfundstein, Ana Filipa Gonçalves, Antonella Catalano, Peter J. Wild,  and Ian J. Frew
19753-19766
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Programmed death-ligand 1 expression by digital image analysis advances thyroid cancer diagnosis among encapsulated follicular lesions

Programmed death-ligand 1 expression by digital image analysis advances thyroid cancer diagnosis among encapsulated follicular lesions

https://doi.org/10.18632/oncotarget.24833

Anne M.-Y. Hsieh, Olena Polyakova, Guodong Fu, Ronald S. Chazen, Christina MacMillan, Ian J. Witterick, Ranju Ralhan,  and Paul G. Walfish
19767-19782
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gene-specific methylation profiles in BRCA-mutation positive and BRCA-mutation negative male breast cancers

Gene-specific methylation profiles in BRCA-mutation positive and BRCA-mutation negative male breast cancers

https://doi.org/10.18632/oncotarget.24856

Piera Rizzolo, Valentina Silvestri, Virginia Valentini, Veronica Zelli, Ines Zanna, Giovanna Masala, Simonetta Bianchi, Domenico Palli,  and Laura Ottini
19783-19792
Abstract  |  PDF  |  HTML  |  Order a Reprint

Exosomal miRNAs species in the blood of small cell and non-small cell lung cancer patients

Exosomal miRNAs species in the blood of small cell and non-small cell lung cancer patients

https://doi.org/10.18632/oncotarget.24857

Valeriy Poroyko, Tamara Mirzapoiazova, Arin Nam, Isa Mambetsariev, Bolot Mambetsariev, Xiwei Wu, Aliya Husain, Everett E. Vokes, Deric L. Wheeler,  and Ravi Salgia
19793-19806
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hormone replacement therapy decreases the risk of tinnitus in menopausal women: a nationwide study

Hormone replacement therapy decreases the risk of tinnitus in menopausal women: a nationwide study

https://doi.org/10.18632/oncotarget.24452

Hsin-Chien Chen, Chi-Hsiang Chung, Vincent C.F. Chen, Yu-Chi Wang,  and Wu-Chien Chien
19807-19816
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association between homologous recombination repair gene mutations and response to oxaliplatin in pancreatic cancer

Association between homologous recombination repair gene mutations and response to oxaliplatin in pancreatic cancer

https://doi.org/10.18632/oncotarget.24865

Tomohiro Kondo, Masashi Kanai, Tadayuki Kou, Tomohiro Sakuma, Hiroaki Mochizuki, Mayumi Kamada, Masahiko Nakatsui, Norimitsu Uza, Yuzo Kodama, Toshihiko Masui, Kyoichi Takaori, Shigemi Matsumoto, Hidehiko Miyake, Yasushi Okuno,  and Manabu Muto
19817-19825
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Using weighted regression model for estimating cohort effect in age-period contingency table data

Using weighted regression model for estimating cohort effect in age-period contingency table data

https://doi.org/10.18632/oncotarget.24868

I-Shiang Tzeng, Chau Yee Ng, Jau-Yuan Chen, Li-Shya Chen,  and Chin-Chieh Wu
19826-19835
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Molecular imaging with positron emission tomography and computed tomography (PET/CT) for selecting first-line targeted treatment in metastatic breast cancer: a cost-effectiveness study

Molecular imaging with positron emission tomography and computed tomography (PET/CT) for selecting first-line targeted treatment in metastatic breast cancer: a cost-effectiveness study

https://doi.org/10.18632/oncotarget.24869

Rositsa G. Koleva-Kolarova, Marcel J.W. Greuter, Talitha L. Feenstra, Karin M. Vermeulen, Erik F.J. de Vries, David Parkin, Erik Buskens,  and Geertruida H. de Bock
19836-19846
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cisplatin-induced ERK1/2 activity promotes G1 to S phase progression which leads to chemoresistance of ovarian cancer cells

Cisplatin-induced ERK1/2 activity promotes G1 to S phase progression which leads to chemoresistance of ovarian cancer cells

https://doi.org/10.18632/oncotarget.24884

Michal Kielbik, Damian Krzyzanowski, Bartlomiej Pawlik,  and Magdalena Klink
19847-19860
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Statin use and survival in patients with metastatic castration-resistant prostate cancer treated with abiraterone or enzalutamide after docetaxel failure: the international retrospective observational STABEN study

Statin use and survival in patients with metastatic castration-resistant prostate cancer treated with abiraterone or enzalutamide after docetaxel failure: the international retrospective observational STABEN study

https://doi.org/10.18632/oncotarget.24888

Jacob A. Gordon, Carlo Buonerba, Gregory Pond, Daniel Crona, Silke Gillessen, Giuseppe Lucarelli, Sabrina Rossetti, Tanya Dorff, Salvatore Artale, Jennifer A. Locke, Davide Bosso, Matthew Ivan Milowsky, Mira Sofie Witek, Michele Battaglia, Sandro Pignata, Cyrus Cherhroudi, Michael E. Cox, Pietro De Placido, Dario Ribera, Aurelius Omlin, Gaetano Buonocore, Kim Chi, Christian Kollmannsberger, Daniel Khalaf, Gaetano Facchini, Guru Sonpavde, Sabino De Placido, Bernhard J. Eigl,  and Giuseppe Di Lorenzo
19861-19873
Abstract  |  PDF  |  HTML  |  Order a Reprint

Ceramide species are elevated in human breast cancer and are associated with less aggressiveness

Ceramide species are elevated in human breast cancer and are associated with less aggressiveness

https://doi.org/10.18632/oncotarget.24903

Kazuki Moro, Tsutomu Kawaguchi, Junko Tsuchida, Emmanuel Gabriel, Qianya Qi, Li Yan, Toshifumi Wakai, Kazuaki Takabe,  and Masayuki Nagahashi
19874-19890
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeted next generation sequencing of well-differentiated/dedifferentiated liposarcoma reveals novel gene amplifications and mutations

Targeted next generation sequencing of well-differentiated/dedifferentiated liposarcoma reveals novel gene amplifications and mutations

https://doi.org/10.18632/oncotarget.24924

Neeta Somaiah, Hannah C. Beird, Andrea Barbo, Juhee Song, Kenna R. Mills Shaw, Wei-Lien Wang, Karina Eterovic, Ken Chen, Alexander Lazar, Anthony P. Conley, Vinod Ravi, Patrick Hwu, Andrew Futreal, George Simon, Funda Meric-Bernstam,  and David Hong
19891-19899
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Response to clopidogrel is associated with early neurological deterioration after acute ischemic stroke

Response to clopidogrel is associated with early neurological deterioration after acute ischemic stroke

https://doi.org/10.18632/oncotarget.24945

Xingyang Yi, Jing Lin, Yanfen Wang, Ju Zhou, Qiang Zhou,  and Chun Wang
19900-19910
Abstract  |  PDF  |  HTML  |  Order a Reprint

Over-activation of AKT signaling leading to 5-Fluorouracil resistance in SNU-C5/5-FU cells

Over-activation of AKT signaling leading to 5-Fluorouracil resistance in SNU-C5/5-FU cells

https://doi.org/10.18632/oncotarget.24952

Eun-Ji Kim, Gyeoung-Jin Kang, Jung-Il Kang, Hye-Jin Boo, Jin Won Hyun, Young Sang Koh, Weon-Young Chang, Young Ree Kim, Jung-Mi Kwon, Young Hee Maeng, Eun-Sook Yoo, Chang Hoon Lee,  and Hee-Kyoung Kang
19911-19928
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Trabectedin modulates the senescence-associated secretory phenotype and promotes cell death in senescent tumor cells by targeting NF-κB

Trabectedin modulates the senescence-associated secretory phenotype and promotes cell death in senescent tumor cells by targeting NF-κB

https://doi.org/10.18632/oncotarget.24961

Simona Camorani, Laura Cerchia, Monica Fedele, Eugenio Erba, Maurizio D’Incalci,  and Elvira Crescenzi
19929-19944
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Histology-dependent prognostic role of pERK and p53 protein levels in early-stage non-small cell lung cancer

Histology-dependent prognostic role of pERK and p53 protein levels in early-stage non-small cell lung cancer

https://doi.org/10.18632/oncotarget.24977

Álvaro Quintanal-Villalonga, Mariló Mediano, Irene Ferrer, Ricardo Meléndez, Andrés Carranza-Carranza, Rocío Suárez, Amancio Carnero, Sonia Molina- Pinelo,  and Luis Paz-Ares
19945-19960
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA signatures and Foxp3+ cell count correlate with relapse occurrence in follicular lymphoma

MicroRNA signatures and Foxp3+ cell count correlate with relapse occurrence in follicular lymphoma

https://doi.org/10.18632/oncotarget.24987

Giorgio Malpeli, Stefano Barbi, Corinna Greco, Simonetta Zupo, Anna Bertolaso, Maria Teresa Scupoli, Mauro Krampera, Paul Takam Kamga, Carlo Maria Croce, Aldo Scarpa,  and Alberto Zamò
19961-19979
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Androgen receptor: a potential therapeutic target for glioblastoma

Androgen receptor: a potential therapeutic target for glioblastoma

https://doi.org/10.18632/oncotarget.25007

Nomi Zalcman, Tamar Canello, Haim Ovadia, Hanna Charbit, Bracha Zelikovitch, Anat Mordechai, Yakov Fellig, Stav Rabani, Tal Shahar, Alexander Lossos,  and Iris Lavon
19980-19993
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Development of novel monoclonal antibodies against CD109 overexpressed in human pancreatic cancer

Development of novel monoclonal antibodies against CD109 overexpressed in human pancreatic cancer

https://doi.org/10.18632/oncotarget.25017

Gustavo A. Arias-Pinilla, Angus G. Dalgleish, Satvinder Mudan, Izhar Bagwan, Anthony J. Walker,  and Helmout Modjtahedi
19994-20007
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Periostin attenuates tumor growth by inducing apoptosis in colitis-related colorectal cancer

Periostin attenuates tumor growth by inducing apoptosis in colitis-related colorectal cancer

https://doi.org/10.18632/oncotarget.25026

Yusuke Shimoyama, Keiichi Tamai, Rie Shibuya, Mao Nakamura, Mai Mochizuki, Kazunori Yamaguchi, Yoichi Kakuta, Yoshitaka Kinouchi, Ikuro Sato, Akira Kudo, Tooru Shimosegawa,  and Kennichi Satoh
20008-20017
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss of inter-cellular cooperation by complete epithelial-mesenchymal transition supports favorable outcomes in basal breast cancer patients

Loss of inter-cellular cooperation by complete epithelial-mesenchymal transition supports favorable outcomes in basal breast cancer patients

https://doi.org/10.18632/oncotarget.25034

Anne Grosse-Wilde, Rolf E Kuestner, Stephanie M Skelton, Ellie MacIntosh, Aymeric Fouquier d’Hérouël, Gökhan Ertaylan, Antonio del Sol, Alexander Skupin,  and Sui Huang
20018-20033
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic impact of programmed cell death ligand 1 (PD-L1) expression and its association with epithelial-mesenchymal transition in extrahepatic cholangiocarcinoma

Prognostic impact of programmed cell death ligand 1 (PD-L1) expression and its association with epithelial-mesenchymal transition in extrahepatic cholangiocarcinoma

https://doi.org/10.18632/oncotarget.25050

Takashi Ueno, Takahiro Tsuchikawa, Kanako C. Hatanaka, Yutaka Hatanaka, Tomoko Mitsuhashi, Yoshitsugu Nakanishi, Takehiro Noji, Toru Nakamura, Keisuke Okamura, Yoshihiro Matsuno,  and Satoshi Hirano
20034-20047
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Implantable wireless powered light emitting diode (LED) for near-infrared photoimmunotherapy: device development and experimental assessment in vitro and in vivo

Implantable wireless powered light emitting diode (LED) for near-infrared photoimmunotherapy: device development and experimental assessment in vitro and in vivo

https://doi.org/10.18632/oncotarget.25068

Kohei Nakajima, Toshihiro Kimura, Hideo Takakura, Yasuo Yoshikawa, Atsushi Kameda, Takayuki Shindo, Kazuhide Sato, Hisataka Kobayashi,  and Mikako Ogawa
20048-20057
Abstract  |  PDF  |  HTML  |  Order a Reprint

Single-cell genetic analysis validates cytopathological identification of circulating cancer cells in patients with clear cell renal cell carcinoma

Single-cell genetic analysis validates cytopathological identification of circulating cancer cells in patients with clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.25102

Lucile Broncy, Basma Ben Njima, Arnaud Méjean, Christophe Béroud, Khaled Ben Romdhane, Marius Ilie, Veronique Hofman, Jane Muret, Paul Hofman, Habiba Chaabouni Bouhamed,  and Patrizia Paterlini-Bréchot
20058-20074
Abstract  |  PDF  |  HTML  |  Order a Reprint

S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth

S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth

https://doi.org/10.18632/oncotarget.24744

Patrick Casara, James Davidson, Audrey Claperon, Gaëtane Le Toumelin-Braizat, Meike Vogler, Alain Bruno, Maïa Chanrion, Gaëlle Lysiak-Auvity, Thierry Le Diguarher, Jérôme-Benoît Starck, Ijen Chen, Neil Whitehead, Christopher Graham, Natalia Matassova, Pawel Dokurno, Christopher Pedder, Youzhen Wang, Shumei Qiu, Anne-Marie Girard, Emilie Schneider, Fabienne Gravé, Aurélie Studeny, Ghislaine Guasconi, Francesca Rocchetti, Sophie Maïga, Jean-Michel Henlin, Frédéric Colland, Laurence Kraus-Berthier, Steven Le Gouill, Martin J.S. Dyer, Roderick Hubbard, Mike Wood, Martine Amiot, Gerald M. Cohen, John A. Hickman, Erick Morris, James Murray,  and Olivier Geneste
20075-20088
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Baicalein and baicalin inhibit colon cancer using two distinct fashions of apoptosis and senescence

Baicalein and baicalin inhibit colon cancer using two distinct fashions of apoptosis and senescence

https://doi.org/10.18632/oncotarget.24015

Jie Dou, Zhou Wang, Leon Ma, Bo Peng, Ke Mao, Chengqin Li, Mengqi Su, Changlin Zhou,  and Guangyong Peng
20089-20102
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Clinical Research Papers

Low-dose CT with adaptive statistical iterative reconstruction for evaluation of urinary stone

Low-dose CT with adaptive statistical iterative reconstruction for evaluation of urinary stone

https://doi.org/10.18632/oncotarget.25047

Xiaohu Li, Hongmin Shu, Yifei Zhang, Xiaoshu Li, Jian Song, Junhua Du, Yinfeng Qian, Bin Liu,  and Yongqiang Yu
20103-20111
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DWI - histology: a possible means of determining degree of liver fibrosis?

DWI - histology: a possible means of determining degree of liver fibrosis?

https://doi.org/10.18632/oncotarget.24981

Niklas Verloh, Kirsten Utpatel, Michael Haimerl, Florian Zeman, Claudia Fellner, Marc Dahlke, Philipp Renner, Timo Seyfried, Martina Müller, Christian Stroszczynski, Matthias Evert,  and Philipp Wiggermann
20112-20118
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Reviews

Mouse models of multiple myeloma: technologic platforms and perspectives

Mouse models of multiple myeloma: technologic platforms and perspectives

https://doi.org/10.18632/oncotarget.24614

Marco Rossi, Cirino Botta, Mariamena Arbitrio, Rosa Daniela Grembiale, Pierosandro Tagliaferri,  and Pierfrancesco Tassone
20119-20133
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Non-invasive tumor genotyping using radiogenomic biomarkers, a systematic review and oncology-wide pathway analysis

Non-invasive tumor genotyping using radiogenomic biomarkers, a systematic review and oncology-wide pathway analysis

https://doi.org/10.18632/oncotarget.24893

Robin W. Jansen, Paul van Amstel, Roland M. Martens, Irsan E. Kooi, Pieter Wesseling, Adrianus J. de Langen, Catharina W. Menke-Van der Houven van Oordt, Bernard H.E. Jansen, Annette C. Moll, Josephine C. Dorsman, Jonas A. Castelijns, Pim de Graaf,  and Marcus C. de Jong
20134-20155
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Lysyl oxidase family members in urological tumorigenesis and fibrosis

Lysyl oxidase family members in urological tumorigenesis and fibrosis

https://doi.org/10.18632/oncotarget.24948

Tao Li, Changjing Wu, Liang Gao, Feng Qin, Qiang Wei,  and Jiuhong Yuan
20156-20164
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Intravital microscopy in the study of the tumor microenvironment: from bench to human application

Intravital microscopy in the study of the tumor microenvironment: from bench to human application

https://doi.org/10.18632/oncotarget.24957

Emmanuel M. Gabriel, Daniel T. Fisher, Sharon Evans, Kazuaki Takabe,  and Joseph J. Skitzki
20165-20178
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Deciphering the roles of lncRNAs in breast development and disease

Deciphering the roles of lncRNAs in breast development and disease

https://doi.org/10.18632/oncotarget.24591

John Lalith Charles Richard,  and Pieter Johan Adam Eichhorn
20179-20212
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Case Reports

Successful rechallenge with ceritinib after leukocytoclastic vasculitis during ceritinib treatment for non-small cell lung cancer harboring the EML4-ALK fusion protein

Successful rechallenge with ceritinib after leukocytoclastic vasculitis during ceritinib treatment for non-small cell lung cancer harboring the EML4-ALK fusion protein

https://doi.org/10.18632/oncotarget.24765

Tamio Okimoto, Yukari Tsubata, Takamasa Hotta, Megumi Hamaguchi, Takae Okuno, Yohei Shiratsuki, Akari Kodama, Mika Nakao, Yoshihiro Amano, Shunichi Hamaguchi, Noriaki Kurimoto, Reiko Tobita,  and Takeshi Isobe
20213-20218
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Corrections

Correction: Discovery of a FLT3 inhibitor LDD1937 as an anti-leukemic agent for acute myeloid leukemia

Correction: Discovery of a FLT3 inhibitor LDD1937 as an anti-leukemic agent for acute myeloid leukemia

https://doi.org/10.18632/oncotarget.25141

Hyo Jeong Lee, Jungeun Lee, Pyeonghwa Jeong, Jungil Choi, Juhwa Baek, Su Jin Ahn, Yeongyu Moon, Jeong Doo Heo, Young Hee Choi, Young-Won Chin, Yong-Chul Kim,  and Sun-Young Han
20219-20219
Correction  |  PDF

Correction: An updated meta-analysis of the prognostic value of decreased E-cadherin expression in ovarian cancer

Correction: An updated meta-analysis of the prognostic value of decreased E-cadherin expression in ovarian cancer

https://doi.org/10.18632/oncotarget.25222

LiLi Yu, Xiaoli Hua, Yu Yang, Ke Li, Qilin Zhang,  and Lixiu Yu
20220-20220
Correction  |  PDF

Correction: MMP-3 gene polymorphisms are associated with increased risk of osteoarthritis in Chinese men

Correction: MMP-3 gene polymorphisms are associated with increased risk of osteoarthritis in Chinese men

https://doi.org/10.18632/oncotarget.25223

Wen Guo, Pengcheng Xu, Tianbo Jin, Jihong Wang, Dongsheng Fan, Zengtao Hao, Yuntao Ji, Shangfei Jing, Chaoqian Han, Jieli Du, Dong Jiang, Shuzheng Wen,  and Jianzhong Wang
20221-20221
Correction  |  PDF


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