Oncotarget

Vol 9, No 21

March 20, 2018

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About The Cover

The cover for issue 21 of Oncotarget features Figure 6, "Kinome drug response overall and by subnetwork," from Collins, et al.

Table of Contents

Research Papers: Immunology

The glucocorticoid receptor in recipient cells keeps cytokine secretion in acute graft-versus-host disease at bay

The glucocorticoid receptor in recipient cells keeps cytokine secretion in acute graft-versus-host disease at bay

https://doi.org/10.18632/oncotarget.24602

Tina Baake, Katharina Jörß, Jennifer Suennemann, Laura Roßmann, Hanibal Bohnenberger, Jan P. Tuckermann, Holger M. Reichardt, Henrike J. Fischer,  and Sybille D. Reichardt
15437-15450
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Research Papers: Chromosome

Replication-incompetent gammaretroviral and lentiviral vector-based insertional mutagenesis screens identify prostate cancer progression genes

Replication-incompetent gammaretroviral and lentiviral vector-based insertional mutagenesis screens identify prostate cancer progression genes

https://doi.org/10.18632/oncotarget.24503

Victor M. Bii, Casey P. Collins, Jonah D. Hocum,  and Grant D. Trobridge
15451-15463
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers

Ajuba receptor mediates the internalization of tumor-secreted GRP78 into macrophages through different endocytosis pathways

Ajuba receptor mediates the internalization of tumor-secreted GRP78 into macrophages through different endocytosis pathways

https://doi.org/10.18632/oncotarget.24090

Xiaoqin La, Lichao Zhang, Hanqing Li, Zhuoyu Li, Guisheng Song, Peng Yang,  and Yufei Yang
15464-15479
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Proteomic analysis defines kinase taxonomies specific for subtypes of breast cancer

Proteomic analysis defines kinase taxonomies specific for subtypes of breast cancer

https://doi.org/10.18632/oncotarget.24337

Kyla A.L. Collins, Timothy J. Stuhlmiller, Jon S. Zawistowski, Michael P. East, Trang T. Pham, Claire R. Hall, Daniel R. Goulet, Samantha M. Bevill, Steven P. Angus, Sara H. Velarde, Noah Sciaky, Tudor I. Oprea, Lee M. Graves, Gary L. Johnson,  and Shawn M. Gomez
15480-15497
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combination therapy of chitosan, gynostemma, and motherwort alleviates the progression of experimental rat chronic renal failure by inhibiting STAT1 activation

Combination therapy of chitosan, gynostemma, and motherwort alleviates the progression of experimental rat chronic renal failure by inhibiting STAT1 activation

https://doi.org/10.18632/oncotarget.24125

Wenxia Bai, Shudong Wang, Shanshan An, Mengjie Guo, Guangming Gong, Wenya Liu, Shaoxin Ma, Xin Li, Jihua Fu,  and Wenbing Yao
15498-15511
Abstract  |  PDF  |  HTML  |  Order a Reprint

The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter

The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter

https://doi.org/10.18632/oncotarget.24496

Barbara Fazi, Sabrina Garbo, Nicola Toschi, Annunziato Mangiola, Malinska Lombari, Daria Sicari, Cecilia Battistelli, Silvia Galardi, Alessandro Michienzi, Gianluca Trevisi, Rona Harari-Steinfeld, Carla Cicchini,  and Silvia Anna Ciafrè
15512-15525
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Systematic characterization of autophagy-related genes during the adipocyte differentiation using public-access data

Systematic characterization of autophagy-related genes during the adipocyte differentiation using public-access data

https://doi.org/10.18632/oncotarget.24506

Mahmoud Ahmed, Huynh Quoc Nguyen, Jin Seok Hwang, Sahib Zada, Trang Huyen Lai, Sang Soo Kang,  and Deok Ryong Kim
15526-15541
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Serum levels of soluble CD163 and CXCL5 may be predictive markers for immune-related adverse events in patients with advanced melanoma treated with nivolumab: a pilot study

Serum levels of soluble CD163 and CXCL5 may be predictive markers for immune-related adverse events in patients with advanced melanoma treated with nivolumab: a pilot study

https://doi.org/10.18632/oncotarget.24509

Taku Fujimura, Yota Sato, Kayo Tanita, Yumi Kambayashi, Atsushi Otsuka, Yasuhiro Fujisawa, Koji Yoshino, Shigeto Matsushita, Takeru Funakoshi, Hiroo Hata, Yuki Yamamoto, Hiroshi Uchi, Yumi Nonomura, Ryota Tanaka, Megumi Aoki, Keisuke Imafuku, Hisako Okuhira, Sadanori Furudate, Takanori Hidaka,  and Setsuya Aiba
15542-15551
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Description of organ-specific phenotype, and functional characteristics of tissue resident lymphocytes from liver transplantation donor and research on immune tolerance mechanism of liver

Description of organ-specific phenotype, and functional characteristics of tissue resident lymphocytes from liver transplantation donor and research on immune tolerance mechanism of liver

https://doi.org/10.18632/oncotarget.24514

Yunpeng Shi, Ping Zhang, Guangyi Wang, Xingkai Liu, Xiaodong Sun, Xin Zhang, Haijun Li, Jun Qi, Lei Ding, Ting Li, Ruoyan Zhang, Yuguo Chen, Jianpeng Zhou, Guoyue Lv,  and Zhengkun Tu
15552-15565
Abstract  |  PDF  |  HTML  |  Order a Reprint

Relationship between the agonist activity of synthetic ligands of TRAIL-R2 and their cell surface binding modes

Relationship between the agonist activity of synthetic ligands of TRAIL-R2 and their cell surface binding modes

https://doi.org/10.18632/oncotarget.24526

Neila Chekkat, Caterina M. Lombardo, Cendrine Seguin, Marie-Charlotte Lechner, Florent Dufour, Yves Nominé, Marcella De Giorgi, Benoit Frisch, Olivier Micheau, Gilles Guichard, Danièle Altschuh,  and Sylvie Fournel
15566-15578
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Grape seed procyanidin extract against lung cancer: the role of microrna-106b, bioavailability, and bioactivity

Grape seed procyanidin extract against lung cancer: the role of microrna-106b, bioavailability, and bioactivity

https://doi.org/10.18632/oncotarget.24528

Bingye Xue, Qing-Yi Lu, Larry Massie, Clifford Qualls,  and Jenny T. Mao
15579-15590
Abstract  |  PDF  |  HTML  |  Order a Reprint

Treatment of oral cancer using magnetized paclitaxel

Treatment of oral cancer using magnetized paclitaxel

https://doi.org/10.18632/oncotarget.24570

Rina Nakakaji, Masanari Umemura, Kenji Mitsudo, Jeong-Hwan Kim, Yujiro Hoshino, Itaru Sato, Takatsugu Masuda, Masahiro Yamamoto, Mitomu Kioi, Toshiyuki Koizumi, Takayuki Fujita, Utako Yokoyama, Masaki Iida, Motohiko Sato, Hiroshi Sato, Shoko Murofushi, Sayaka Shibata, Ichio Aoki, Haruki Eguchi, Iwai Tohnai,  and Yoshihiro Ishikawa
15591-15605
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Selective lysis of breast carcinomas by simultaneous stimulation of sodium channels and blockade of sodium pumps

Selective lysis of breast carcinomas by simultaneous stimulation of sodium channels and blockade of sodium pumps

https://doi.org/10.18632/oncotarget.24581

Harry J. Gould III, Jack Norleans, T. David Ward, Chasiti Reid,  and Dennis Paul
15606-15615
Abstract  |  PDF  |  HTML  |  Order a Reprint

New antimicrobial peptide kills drug-resistant pathogens without detectable resistance

New antimicrobial peptide kills drug-resistant pathogens without detectable resistance

https://doi.org/10.18632/oncotarget.24582

Jong-Kook Lee, Tudor Luchian,  and Yoonkyung Park
15616-15634
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Deletion of sphingosine kinase 1 inhibits liver tumorigenesis in diethylnitrosamine-treated mice

Deletion of sphingosine kinase 1 inhibits liver tumorigenesis in diethylnitrosamine-treated mice

https://doi.org/10.18632/oncotarget.24583

Jinbiao Chen, Yanfei Qi, Yang Zhao, Dominik Kaczorowski, Timothy A. Couttas, Paul R. Coleman, Anthony S. Don, Patrick Bertolino, Jennifer R. Gamble, Mathew A. Vadas, Pu Xia,  and Geoffrey W. McCaughan
15635-15649
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sympatho-adrenergic activation by endurance exercise: Effect on metanephrines spillover and its role in predicting athlete’s performance

Sympatho-adrenergic activation by endurance exercise: Effect on metanephrines spillover and its role in predicting athlete’s performance

https://doi.org/10.18632/oncotarget.24584

Elisa Danese, Cantor Tarperi, Gian Luca Salvagno, Alessandra Guzzo, Fabian Sanchis-Gomar, Luca Festa, Luciano Bertinato, Martina Montagnana, Federico Schena,  and Giuseppe Lippi
15650-15657
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CDK4/6 inhibition as maintenance and combination therapy for high grade serous ovarian cancer

CDK4/6 inhibition as maintenance and combination therapy for high grade serous ovarian cancer

https://doi.org/10.18632/oncotarget.24585

Mangala Iyengar, Patrick O’Hayer, Alex Cole, Tara Sebastian, Kun Yang, Lan Coffman,  and Ronald J. Buckanovich
15658-15672
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer

BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer

https://doi.org/10.18632/oncotarget.24590

Sarah Sheilds, Emer Conroy, Tony O'Grady, Alo McGoldrick, Kate Connor, Mark P. Ward, Zivile Useckaite, Eugene Dempsey, Rebecca Reilly, Yue Fan, Anthony Chubb, David Gomez Matallanas, Elaine W. Kay, Darran O'Connor, Amanda McCann, William M. Gallagher,  and Judith A. Coppinger
15673-15690
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss of neutrophil polarization in colon carcinoma liver metastases of mice with an inducible, liver-specific IGF-I deficiency

Loss of neutrophil polarization in colon carcinoma liver metastases of mice with an inducible, liver-specific IGF-I deficiency

https://doi.org/10.18632/oncotarget.24593

Roni F. Rayes, Simon Milette, Maria Celia Fernandez, Boram Ham, Ni Wang, France Bourdeau, Stephanie Perrino, Shoshana Yakar,  and Pnina Brodt
15691-15704
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of PLOD3 promotes tumor progression and poor prognosis in gliomas

Overexpression of PLOD3 promotes tumor progression and poor prognosis in gliomas

https://doi.org/10.18632/oncotarget.24594

Chia-Kuang Tsai, Li-Chun Huang, Wen-Chiuan Tsai, Shih-Ming Huang, Jiunn-Tay Lee,  and Dueng-Yuan Hueng
15705-15720
Abstract  |  PDF  |  HTML  |  Order a Reprint

IL-8 associates with a pro-angiogenic and mesenchymal subtype in glioblastoma

IL-8 associates with a pro-angiogenic and mesenchymal subtype in glioblastoma

https://doi.org/10.18632/oncotarget.24595

Siobhan Conroy, Frank A.E. Kruyt, Michiel Wagemakers, Krishna P.L. Bhat,  and Wilfred F.A. den Dunnen
15721-15731
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Radiofrequency assisted pancreaticoduodenectomy for palliative surgical resection of locally advanced pancreatic adenocarcinoma

Radiofrequency assisted pancreaticoduodenectomy for palliative surgical resection of locally advanced pancreatic adenocarcinoma

https://doi.org/10.18632/oncotarget.24596

Jayant Kumar, Isabella Reccia, Mikael Sordegren, Tomokazu Kusano, Artur Zanellato, Madhava Pai, Duncan Spalding, Dimitris Zacharoulis,  and Nagy Habib
15732-15739
Abstract  |  PDF  |  HTML  |  Order a Reprint

The long non-coding RNA HOTAIR is transcriptionally activated by HOXA9 and is an independent prognostic marker in patients with malignant glioma

The long non-coding RNA HOTAIR is transcriptionally activated by HOXA9 and is an independent prognostic marker in patients with malignant glioma

https://doi.org/10.18632/oncotarget.24597

Ana Xavier-Magalhães, Céline S. Gonçalves, Anne Fogli, Tatiana Lourenço, Marta Pojo, Bruno Pereira, Miguel Rocha, Maria Celeste Lopes, Inês Crespo, Olinda Rebelo, Herminio Tão, João Lima, Ricardo Moreira, Afonso A. Pinto, Chris Jones, Rui M. Reis, Joseph F. Costello, Philippe Arnaud, Nuno Sousa,  and Bruno M. Costa
15740-15756
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of adjuvant hormonotherapy on radiation-induced breast fibrosis according to the individual radiosensitivity: results of a multicenter prospective French trial

Impact of adjuvant hormonotherapy on radiation-induced breast fibrosis according to the individual radiosensitivity: results of a multicenter prospective French trial

https://doi.org/10.18632/oncotarget.24606

Céline Bourgier, Florence Castan, Olivier Riou, Tan-Dat Nguyen, Karine Peignaux, Claire Lemanski, Jean-Léon Lagrange, Youlia Kirova, Eric Lartigau, Yazid Belkacemi, Sofia Rivera, Georges Noël, Sébastien Clippe, Françoise Mornex, Christophe Hennequin, Sophie Gourgou, Muriel Brengues, Pascal Fenoglietto, Esat Mahmut Ozsahin,  and David Azria
15757-15765
Abstract  |  PDF  |  HTML  |  Order a Reprint

Calcium-sensing receptor (CaSR) promotes development of bone metastasis in renal cell carcinoma

Calcium-sensing receptor (CaSR) promotes development of bone metastasis in renal cell carcinoma

https://doi.org/10.18632/oncotarget.24607

Sebastian Frees, Ines Breuksch, Tobias Haber, Heide-Katharina Bauer, Claudia Chavez-Munoz, Peter Raven, Igor Moskalev, Ninadh D´Costa, Zheng Tan, Mads Daugaard, Joachim W. Thüroff, Axel Haferkamp, Dirk Prawitt, Alan So,  and Walburgis Brenner
15766-15779
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pomalidomide enhanced gemcitabine and nab-paclitaxel on pancreatic cancer both in vitro and in vivo

Pomalidomide enhanced gemcitabine and nab-paclitaxel on pancreatic cancer both in vitro and in vivo

https://doi.org/10.18632/oncotarget.24608

Nobuhiro Saito, Yoshihiro Shirai, Tadashi Uwagawa, Takashi Horiuchi, Hiroshi Sugano, Koichiro Haruki, Hiroaki Shiba, Toya Ohashi,  and Katsuhiko Yanaga
15780-15791
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Value-based genomics

Value-based genomics

https://doi.org/10.18632/oncotarget.24353

Jun Gong, Kathy Pan, Marwan Fakih, Sumanta Pal,  and Ravi Salgia
15792-15815
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Corrections

Correction: MicroRNA-29a increased the intestinal membrane permeability of colonic epithelial cells in irritable bowel syndrome rats

Correction: MicroRNA-29a increased the intestinal membrane permeability of colonic epithelial cells in irritable bowel syndrome rats

https://doi.org/10.18632/oncotarget.24848

Guanqun Chao, Yingying Wang, Shuo Zhang, Weilin Yang, Zheying Ni,  and Xuliang Zheng
15816-15816
Correction  |  PDF

Correction: The outcomes and prognostic factors of acute respiratory failure in the patients 90 years old and over

Correction: The outcomes and prognostic factors of acute respiratory failure in the patients 90 years old and over

https://doi.org/10.18632/oncotarget.24864

Wan-Ling Chen, Chin-Ming Chen, Shu-Chen Kung, Ching-Min Wang, Chih-Cheng Lai,  and Chien-Ming Chao
15817-15817
Correction  |  PDF


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