Oncotarget

Vol 9, No 7

January 26, 2018

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About The Cover

The cover for issue 7 of Oncotarget features Figure 1, "Flow diagram for patient inclusion in the analysis data set," from Wadia, et al.

Table of Contents

Letters to the Editor

Competing risks and cancer–specific mortality: why it matters

Competing risks and cancer–specific mortality: why it matters

https://doi.org/10.18632/oncotarget.23729

Kay See Tan, Takashi Eguchi,  and Prasad S. Adusumilli
7272-7273
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Priority Research Papers

A novel suicide gene therapy for the treatment of p16Ink4a-overexpressing tumors

A novel suicide gene therapy for the treatment of p16Ink4a-overexpressing tumors

https://doi.org/10.18632/oncotarget.23752

Jaskaren Kohli, Judith Campisi,  and Marco Demaria
7274-7281
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Inhibition of Mdmx (Mdm4) in vivo induces anti-obesity effects

Inhibition of Mdmx (Mdm4) in vivo induces anti-obesity effects

https://doi.org/10.18632/oncotarget.23837

Ning Kon, Donglai Wang, Tongyuan Li, Le Jiang, Li Qiang,  and Wei Gu
7282-7297
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Research Papers: Gerotarget (Focus on Aging)

Endurance exercise prevents high-fat-diet induced heart and mobility premature aging and dsir2 expression decline in aging Drosophila

Endurance exercise prevents high-fat-diet induced heart and mobility premature aging and dsir2 expression decline in aging Drosophila

https://doi.org/10.18632/oncotarget.23292

Deng-Tai Wen, Lan Zheng, Fan Yang, Han-Zhe Li,  and Wen-Qi Hou
7298-7311
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Research Papers

Evidence that PP2A activity is dispensable for spindle assembly checkpoint-dependent control of Cdk1

Evidence that PP2A activity is dispensable for spindle assembly checkpoint-dependent control of Cdk1

https://doi.org/10.18632/oncotarget.23329

Nando Cervone, Rosa Della Monica, Angela Flavia Serpico, Cinzia Vetrei, Mario Scaraglio, Roberta Visconti,  and Domenico Grieco
7312-7321
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The prevention of chemotherapy induced peripheral neuropathy by concurrent treatment with drugs used for bipolar disease: a retrospective chart analysis in human cancer patients

The prevention of chemotherapy induced peripheral neuropathy by concurrent treatment with drugs used for bipolar disease: a retrospective chart analysis in human cancer patients

https://doi.org/10.18632/oncotarget.23467

Roxanne J. Wadia, Marilyn Stolar, Clarice Grens, Barbara E. Ehrlich,  and Herta H. Chao
7322-7331
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Single cell whole genome sequencing reveals that NFKB1 mutation affects radiotherapy sensitivity in cervical cancer

Single cell whole genome sequencing reveals that NFKB1 mutation affects radiotherapy sensitivity in cervical cancer

https://doi.org/10.18632/oncotarget.23587

Dong Yang, Weiyuan Zhang, JunQing Liang, Kexin Ma, Peng Chen, Danni Lu,  and Wenjing Hao
7332-7340
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Transcriptomes define distinct subgroups of salivary gland adenoid cystic carcinoma with different driver mutations and outcomes

Transcriptomes define distinct subgroups of salivary gland adenoid cystic carcinoma with different driver mutations and outcomes

https://doi.org/10.18632/oncotarget.23641

Candace A. Frerich, Kathryn J. Brayer, Brandon M. Painter, Huining Kang, Yoshitsugu Mitani, Adel K. El-Naggar,  and Scott A. Ness
7341-7358
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A common molecular signature of intestinal-type gastric carcinoma indicates processes related to gastric carcinogenesis

A common molecular signature of intestinal-type gastric carcinoma indicates processes related to gastric carcinogenesis

https://doi.org/10.18632/oncotarget.23670

Renata Binato, Everton Cruz Santos, Mariana Boroni, Samia Demachki, Paulo Assumpção,  and Eliana Abdelhay
7359-7371
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Paeoniflorin regulates osteoclastogenesis and osteoblastogenesis via manipulating NF-κB signaling pathway both in vitro and in vivo

Paeoniflorin regulates osteoclastogenesis and osteoblastogenesis via manipulating NF-κB signaling pathway both in vitro and in vivo

https://doi.org/10.18632/oncotarget.23677

Yanmao Wang, Jiezhi Dai, Yu Zhu, Wanrun Zhong, Shengdi Lu, Hua Chen,  and Yimin Chai
7372-7388
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Genetic correction improves prediction efficiency of serum tumor biomarkers on digestive cancer risk in the elderly Chinese cohort study

Genetic correction improves prediction efficiency of serum tumor biomarkers on digestive cancer risk in the elderly Chinese cohort study

https://doi.org/10.18632/oncotarget.23205

Ke Wang, Yansen Bai, Shi Chen, Jiao Huang, Jing Yuan, Weihong Chen, Ping Yao, Xiaoping Miao, Youjie Wang, Yuan Liang, Xiaomin Zhang, Meian He, Handong Yang, Qingyi Wei, Huan Guo,  and Sheng Wei
7389-7397
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Breast cancer cell-derived exosomes and macrophage polarization are associated with lymph node metastasis

Breast cancer cell-derived exosomes and macrophage polarization are associated with lymph node metastasis

https://doi.org/10.18632/oncotarget.23238

Yin Ji Piao, Hoe Suk Kim, Eun Hye Hwang, Jisu Woo, Meihua Zhang,  and Woo Kyung Moon
7398-7410
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Epigallocatechin-3-gallate suppresses differentiation of adipocytes via regulating the phosphorylation of FOXO1 mediated by PI3K-AKT signaling in 3T3-L1 cells

Epigallocatechin-3-gallate suppresses differentiation of adipocytes via regulating the phosphorylation of FOXO1 mediated by PI3K-AKT signaling in 3T3-L1 cells

https://doi.org/10.18632/oncotarget.23590

Yi Lu, Junye Chen, Tao Xian, Yumeng Zhou, Wanwan Yuan, Mengxi Wang, Yuyang Gan, Kun Wang, Shaofeng Xiong, Cong Ma, Xueying Yu,  and Qiren Huang
7411-7423
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Novel mutational landscapes and expression signatures of lung squamous cell carcinoma

Novel mutational landscapes and expression signatures of lung squamous cell carcinoma

https://doi.org/10.18632/oncotarget.23716

Donghai Xiong, Jing Pan, Yuxin Yin, Hui Jiang, Eva Szabo, Ronald A. Lubet, Yian Wang,  and Ming You
7424-7441
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SALL1 expression in acute myeloid leukemia

SALL1 expression in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.23448

Huda Salman, Xiao Shuai, Anh Thu Nguyen-Lefebvre, Banabihari Giri, Mingqiang Ren, Michael Rauchman, Lynn Robbins, Wei Hou, Hasan Korkaya,  and Yupo Ma
7442-7452
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Expression of uc.189 and its clinicopathologic significance in gynecological cancers

Expression of uc.189 and its clinicopathologic significance in gynecological cancers

https://doi.org/10.18632/oncotarget.23761

Lei Wang, Xing Cheng Wang, Xinyu Li, Yan Gu, Jun Zhou, Shuwan Jiang, Jiajia Liu, Chong Wu, Zhiyan Ding, Yafeng Wan,  and Chenghai Wang
7453-7463
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Involvement of the FOXO6 transcriptional factor in breast carcinogenesis

Involvement of the FOXO6 transcriptional factor in breast carcinogenesis

https://doi.org/10.18632/oncotarget.23779

François Lallemand, Ambre Petitalot, Sophie Vacher, Leanne de Koning, Karim Taouis, Bernard S. Lopez, Sophie Zinn-Justin, Nicole Dalla-Venezia, Walid Chemlali, Anne Schnitzler, Rosette Lidereau, Ivan Bieche,  and Sandrine M. Caputo
7464-7475
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Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer

Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer

https://doi.org/10.18632/oncotarget.23554

Yujiro Nishizawa, Masamitsu Konno, Ayumu Asai, Jun Koseki, Koichi Kawamoto, Norikatsu Miyoshi, Hidekazu Takahashi, Naohiro Nishida, Naotsugu Haraguchi, Daisuke Sakai, Toshihiro Kudo, Taishi Hata, Chu Matsuda, Tsunekazu Mizushima, Taroh Satoh, Yuichiro Doki, Masaki Mori,  and Hideshi Ishii
7476-7486
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Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells

Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells

https://doi.org/10.18632/oncotarget.23556

Dominik Bachmann, Roberta Aliperta, Ralf Bergmann, Anja Feldmann, Stefanie Koristka, Claudia Arndt, Simon Loff, Petra Welzel, Susann Albert, Alexandra Kegler, Armin Ehninger, Marc Cartellieri, Gerhard Ehninger, Martin Bornhäuser, Malte von Bonin, Carsten Werner, Jens Pietzsch, Jörg Steinbach,  and Michael Bachmann
7487-7500
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MALAT1/miR-101-3p/MCL1 axis mediates cisplatin resistance in lung cancer

MALAT1/miR-101-3p/MCL1 axis mediates cisplatin resistance in lung cancer

https://doi.org/10.18632/oncotarget.23483

Huaqi Wang, Li Wang, Guojun Zhang, Chunya Lu, Heying Chu, Rui Yang,  and Guoqiang Zhao
7501-7512
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Early hyperbaric oxygen effects on neuropathic pain and nitric oxide synthase isoforms in CCI rats

Early hyperbaric oxygen effects on neuropathic pain and nitric oxide synthase isoforms in CCI rats

https://doi.org/10.18632/oncotarget.23867

Yuanyuan Ding, Peng Yao, Tao Hong, Zhenkai Han, Baisong Zhao, Weimin Chen,  and Guangyu Zhou
7513-7521
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Diagnostic value of HE4+ circulating tumor cells in patients with suspicious ovarian cancer

Diagnostic value of HE4+ circulating tumor cells in patients with suspicious ovarian cancer

https://doi.org/10.18632/oncotarget.23943

Yan-xiu Guo, Kuang Hong Neoh, Xiao-hong Chang, Yukun Sun, Hong-yan Cheng, Xue Ye, Rui-qiong Ma, Ray P.S. Han,  and Heng Cui
7522-7533
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Prognostic factors associated with a stable MR4.5 achievement in chronic myeloid leukemia patients treated with imatinib

Prognostic factors associated with a stable MR4.5 achievement in chronic myeloid leukemia patients treated with imatinib

https://doi.org/10.18632/oncotarget.23691

Massimo Breccia, Matteo Molica, Gioia Colafigli, Fulvio Massaro, Luisa Quattrocchi, Roberto Latagliata, Marco Mancini, Daniela Diverio, Anna Guarini, Giuliana Alimena,  and Robin Foà
7534-7540
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Dual targeting of mitochondrial function and mTOR pathway as a therapeutic strategy for diffuse intrinsic pontine glioma

Dual targeting of mitochondrial function and mTOR pathway as a therapeutic strategy for diffuse intrinsic pontine glioma

https://doi.org/10.18632/oncotarget.24045

Maria Tsoli, Jie Liu, Laura Franshaw, Han Shen, Cecilia Cheng, MoonSun Jung, Swapna Joshi, Anahid Ehteda, Aaminah Khan, Angel Montero-Carcabosso, Pierre J. Dilda, Philip Hogg,  and David S. Ziegler
7541-7556
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Cryoablation with drug-loaded bead embolization in the treatment of unresectable hepatocellular carcinoma: safety and efficacy analysis

Cryoablation with drug-loaded bead embolization in the treatment of unresectable hepatocellular carcinoma: safety and efficacy analysis

https://doi.org/10.18632/oncotarget.24029

Jian-Ying Zeng, Xiang-Hao Piao, Zhong-Yuan Zou, Qing-Feng Yang, Zi-Lin Qin, Ji-Bing Chen, Liang Zhou, Li-Zhi Niu,  and Jian-Guo Liu
7557-7566
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SCD5 restored expression favors differentiation and epithelial-mesenchymal reversion in advanced melanoma

SCD5 restored expression favors differentiation and epithelial-mesenchymal reversion in advanced melanoma

https://doi.org/10.18632/oncotarget.24085

Rossella Puglisi, Maria Bellenghi, Giada Pontecorvi, Alessandro Gulino, Marina Petrini, Federica Felicetti, Lisabianca Bottero, Gianfranco Mattia,  and Alessandra Carè
7567-7581
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Interaction of renin-angiotensin system gene polymorphisms with hypertension in Chinese patients with type 1 diabetes and retinopathy

Interaction of renin-angiotensin system gene polymorphisms with hypertension in Chinese patients with type 1 diabetes and retinopathy

https://doi.org/10.18632/oncotarget.24100

Yong-Chao Qiao, Yan-Hong Pan, Yan Xu, Xiao-Xi Zhang,  and Hai-Lu Zhao
7582-7589
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Interaction between physical activity, PITX1 rs647161 genetic polymorphism and colorectal cancer risk in a Korean population: a case-control study

Interaction between physical activity, PITX1 rs647161 genetic polymorphism and colorectal cancer risk in a Korean population: a case-control study

https://doi.org/10.18632/oncotarget.24136

Madhawa Neranjan Gunathilake, Jeonghee Lee, Young Ae Cho, Jae Hwan Oh, Hee Jin Chang, Dae Kyung Sohn, Aesun Shin,  and Jeongseon Kim
7590-7603
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SOX9 is a driver of aggressive prostate cancer by promoting invasion, cell fate and cytoskeleton alterations and epithelial to mesenchymal transition

SOX9 is a driver of aggressive prostate cancer by promoting invasion, cell fate and cytoskeleton alterations and epithelial to mesenchymal transition

https://doi.org/10.18632/oncotarget.24123

Jeffrey C. Francis, Amy Capper, Jian Ning, Eleanor Knight, Johann de Bono,  and Amanda Swain
7604-7615
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Alzheimer’s disease is associated with prostate cancer: a population-based study

Alzheimer’s disease is associated with prostate cancer: a population-based study

https://doi.org/10.18632/oncotarget.24139

Herng-Ching Lin, Li-Ting Kao, Shiu-Dong Chung, Chung-Chien Huang, Ben-Chang Shia,  and Chao-Yuan Huang
7616-7622
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Impact of atrial fibrillation on the development of ischemic stroke among cancer patients classified by CHA2DS2-VASc score-a nationwide cohort study

Impact of atrial fibrillation on the development of ischemic stroke among cancer patients classified by CHA2DS2-VASc score-a nationwide cohort study

https://doi.org/10.18632/oncotarget.24143

Wei-Syun Hu,  and Cheng-Li Lin
7623-7630
Abstract  |  PDF  |  HTML  |  Order a Reprint

S100A9+ MDSC and TAM-mediated EGFR-TKI resistance in lung adenocarcinoma: the role of RELB

S100A9+ MDSC and TAM-mediated EGFR-TKI resistance in lung adenocarcinoma: the role of RELB

https://doi.org/10.18632/oncotarget.24146

Po-Hao Feng, Chih-Teng Yu, Kuan-Yuan Chen, Ching-Shan Luo, Shen Ming Wu, Chien-Ying Liu, Lu Wei Kuo, Yao-Fei Chan, Tzu-Tao Chen, Chih-Cheng Chang, Chun-Nin Lee, Hsiao-Chi Chuang, Chiou-Feng Lin, Chia-Li Han, Wei-Hwa Lee,  and Kang-Yun Lee
7631-7643
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A Taiwanese population-based study on the association between chronic tonsillitis and tonsil cancer

A Taiwanese population-based study on the association between chronic tonsillitis and tonsil cancer

https://doi.org/10.18632/oncotarget.24262

Shih-Han Hung, Li-Ting Kao, Chung-Chien Huang, Ben-Chang Shia,  and Herng-Ching Lin
7644-7650
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Meta-Analysis

Association between PIK3CA alteration and prognosis of gastric cancer patients: a meta-analysis

Association between PIK3CA alteration and prognosis of gastric cancer patients: a meta-analysis

https://doi.org/10.18632/oncotarget.23871

Hua Li, Shubo Chen, Hui Li, Jianxin Cui, Yunhe Gao, Dianchao Wu, Shangfeng Luan, Yan Qin, Tongshan Zhai, Dengxiang Liu,  and Zhibin Huo
7651-7659
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of endoglin-assessed microvessel density in cancer patients: a systematic review and meta-analysis

Prognostic value of endoglin-assessed microvessel density in cancer patients: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.23546

Jinguo Zhang, Lingyun Zhang, Qunbo Lin, Weimin Ren,  and Guoxiong Xu
7660-7671
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Anti-PD-1/PD-L1 antibodies versus docetaxel in patients with previously treated non-small-cell lung cancer

Anti-PD-1/PD-L1 antibodies versus docetaxel in patients with previously treated non-small-cell lung cancer

https://doi.org/10.18632/oncotarget.23584

Qi Jiang, Mixue Xie, Mengye He, Feifei Yan, Xiaochen Zhang,  and Sufen Yu
7672-7683
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association between PD-L1 expression and driver gene status in non-small-cell lung cancer: a meta-analysis

Association between PD-L1 expression and driver gene status in non-small-cell lung cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.23969

Bo Lan, Chengxi Ma, Chengyan Zhang, Shoujie Chai, Pingli Wang, Liren Ding,  and Kai Wang
7684-7699
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Prevalence of infant sneezing without colds and prediction of childhood allergy diseases in a prospective cohort study

Prevalence of infant sneezing without colds and prediction of childhood allergy diseases in a prospective cohort study

https://doi.org/10.18632/oncotarget.22338

Kuender D. Yang, Chih-Chiang Wu, Ming-Tsung Lee, Chia-Yu Ou, Jen-Chieh Chang, Chih-Lu Wang, Hau Chuang, Ho-Chang Kuo, Chie-Pein Chen,  and Te-Yao Hsu
7700-7709
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Biomarkers for cognitive decline in patients with diabetes mellitus: evidence from clinical studies

Biomarkers for cognitive decline in patients with diabetes mellitus: evidence from clinical studies

https://doi.org/10.18632/oncotarget.23284

Xue Zhao, Qing Han, You Lv, Lin Sun, Xiaokun Gang,  and Guixia Wang
7710-7726
Abstract  |  PDF  |  HTML  |  Order a Reprint

Low- to high-density lipoprotein cholesterol ratio followed by coronary computed tomography angiography improves coronary plaque classification accuracy

Low- to high-density lipoprotein cholesterol ratio followed by coronary computed tomography angiography improves coronary plaque classification accuracy

https://doi.org/10.18632/oncotarget.23558

Xiyang Hu, Wei Zhang, Nairui Zhao, Rongcheng Zhao,  and Shuofeng Li
7727-7738
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Reviews

Review on comparative efficacy of bevacizumab, panitumumab and cetuximab antibody therapy with combination of FOLFOX-4 in KRAS-mutated colorectal cancer patients

Review on comparative efficacy of bevacizumab, panitumumab and cetuximab antibody therapy with combination of FOLFOX-4 in KRAS-mutated colorectal cancer patients

https://doi.org/10.18632/oncotarget.22471

Surajit Pathak, Sushmitha S, Antara Banerjee, Francesco Marotta, Madhumala Gopinath, Ramachandran Murugesan, Hong Zhang, Bhavani B, Agniswar Girigoswami, Jose Sollano,  and Xiao-Feng Sun
7739-7748
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