Oncotarget

Vol 9, No 3

January 9, 2018

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About The Cover

The cover for issue 3 of Oncotarget features Figure 2, "Overall description of the MTase domain with bound SAM or SAH," from Chatrin, et al.

Table of Contents

Editorial

Targeting lipogenesis in the treatment of metabolic diseases and cancer

Targeting lipogenesis in the treatment of metabolic diseases and cancer

https://doi.org/10.18632/oncotarget.23004

Jose A. Viscarra,  and Hei Sook Sul
2969-2970
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Research Papers

Association of p53 and mitochondrial gene with chemosensitization by metformin in ovarian cancer

Association of p53 and mitochondrial gene with chemosensitization by metformin in ovarian cancer

https://doi.org/10.18632/oncotarget.22863

De-Hua Wei, Yan Wang,  and Hui-Rong Shi
2971-2976
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Comprehensive analysis of gene expression and DNA methylation datasets identify valuable biomarkers for rheumatoid arthritis progression

Comprehensive analysis of gene expression and DNA methylation datasets identify valuable biomarkers for rheumatoid arthritis progression

https://doi.org/10.18632/oncotarget.22918

Gang Fang, Qing Huai Zhang, Qianqian Tang, Zuling Jiang, Shasha Xing, Jianying Li,  and Yuzhou Pang
2977-2983
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Infliction of proteotoxic stresses by impairment of the unfolded protein response or proteasomal inhibition as a therapeutic strategy for mast cell leukemia

Infliction of proteotoxic stresses by impairment of the unfolded protein response or proteasomal inhibition as a therapeutic strategy for mast cell leukemia

https://doi.org/10.18632/oncotarget.23354

Thomas Wilhelm, Fabian Bick, Kerstin Peters, Vrinda Mohta, Boaz Tirosh, John B. Patterson, Behzad Kharabi-Masouleh,  and Michael Huber
2984-3000
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A novel multiplex detection array revealed systemic complement activation in oral squamous cell carcinoma

A novel multiplex detection array revealed systemic complement activation in oral squamous cell carcinoma

https://doi.org/10.18632/oncotarget.22963

Juliane Gallenkamp, Gerrit Spanier, Elisabeth Wörle, Markus Englbrecht, Michael Kirschfink, Roman Greslechner, Regine Braun, Nicole Schäfer, Richard J. Bauer,  and Diana Pauly
3001-3013
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Methylseleninic acid induces NAD(P)H:quinone oxidoreductase-1 expression through activation of NF-E2-related factor 2 in Chang liver cells

Methylseleninic acid induces NAD(P)H:quinone oxidoreductase-1 expression through activation of NF-E2-related factor 2 in Chang liver cells

https://doi.org/10.18632/oncotarget.10289

Jong-Min Park, Do-Hee Kim, Hye-Kyung Na,  and Young-Joon Surh
3014-3028
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Effect of calcium salt of long-chain fatty acids and alfalfa supplementation on performance of Holstein bulls

Effect of calcium salt of long-chain fatty acids and alfalfa supplementation on performance of Holstein bulls

https://doi.org/10.18632/oncotarget.23073

Yang He, Wenjing Niu, Qinghua Qiu, Chuanqi Xia, Taoqi Shao, Haibo Wang, Qianwen Li, Zhantao Yu, Zhibiao Gao, Muhammad Aziz Ur Rahman, Huawei Su,  and Binghai Cao
3029-3042
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Targeting the T-Lak cell originated protein kinase by OTS964 shrinks the size of power-law coded heterogeneous glioma stem cell populations

Targeting the T-Lak cell originated protein kinase by OTS964 shrinks the size of power-law coded heterogeneous glioma stem cell populations

https://doi.org/10.18632/oncotarget.23077

Michiya Sugimori, Yumiko Hayakawa, Masaki Koh, Tomohide Hayashi, Ryoi Tamura,  and Satoshi Kuroda
3043-3059
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Increased risk of testis failure in testicular germ cell tumor survivors undergoing radiotherapy

Increased risk of testis failure in testicular germ cell tumor survivors undergoing radiotherapy

https://doi.org/10.18632/oncotarget.23081

Marco Ghezzi, Luca De Toni, Pierfrancesco Palego, Massimo Menegazzo, Elisa Faggian, Massimiliano Berretta, Francesco Fiorica, Maurizio De Rocco Ponce, Carlo Foresta,  and Andrea Garolla
3060-3068
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Recombinant frizzled1 protein attenuated cardiac hypertrophy after myocardial infarction via the canonical Wnt signaling pathway

Recombinant frizzled1 protein attenuated cardiac hypertrophy after myocardial infarction via the canonical Wnt signaling pathway

https://doi.org/10.18632/oncotarget.23149

Jingjing Fan, Lin Qiu, Hongyang Shu, Ben Ma, Marco Hagenmueller, Johannes H. Riffel, Soeren Meryer, Min Zhang, Stefan E. Hardt, Lin Wang, Ning Zhou, Hongyu Qiu,  and Ning Zhou
3069-3080
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Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastoma

Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastoma

https://doi.org/10.18632/oncotarget.23152

Jia Wang, Yuchen Xie, Xiaobin Bai, Ning Wang, Hai Yu, Zhong Deng, Minxue Lian, Shuo Yu, Hao Liu, Wanfu Xie,  and Maode Wang
3081-3088
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Quantitative analysis of prompt gamma ray imaging during proton boron fusion therapy according to boron concentration

Quantitative analysis of prompt gamma ray imaging during proton boron fusion therapy according to boron concentration

https://doi.org/10.18632/oncotarget.23201

Han-Back Shin, Moo-Sub Kim, Sunmi Kim, Kyu Bom Kim, Joo-Young Jung, Do-Kun Yoon,  and Tae Suk Suh
3089-3096
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Small non-coding RNA profiling in human biofluids and surrogate tissues from healthy individuals: description of the diverse and most represented species

Small non-coding RNA profiling in human biofluids and surrogate tissues from healthy individuals: description of the diverse and most represented species

https://doi.org/10.18632/oncotarget.23203

Giulio Ferrero, Francesca Cordero, Sonia Tarallo, Maddalena Arigoni, Federica Riccardo, Gaetano Gallo, Guglielmo Ronco, Marco Allasia, Neha Kulkarni, Giuseppe Matullo, Paolo Vineis, Raffaele A. Calogero, Barbara Pardini,  and Alessio Naccarati
3097-3111
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Prognostic significance of ST6GalNAc-1 expression in patients with non-metastatic clear cell renal cell carcinoma

Prognostic significance of ST6GalNAc-1 expression in patients with non-metastatic clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.11258

Qi Bai, Li Liu, Wei Xi, Jiajun Wang, Yu Xia, Yang Qu, Ying Xiong, Qilai Long, Jiejie Xu,  and Jianming Guo
3112-3120
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Schisandrol B and schisandrin B inhibit TGFβ1-mediated NF-κB activation via a Smad-independent mechanism

Schisandrol B and schisandrin B inhibit TGFβ1-mediated NF-κB activation via a Smad-independent mechanism

https://doi.org/10.18632/oncotarget.23213

Jung Nyeo Chun, Soonbum Park, Sanghoon Lee, Jae-Kyung Kim, Eun-Jung Park, MinJi Kang, Hye Kyung Kim, Jong Kwan Park, Insuk So,  and Ju-Hong Jeon
3121-3130
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LITAF is a potential tumor suppressor in pancreatic cancer

LITAF is a potential tumor suppressor in pancreatic cancer

https://doi.org/10.18632/oncotarget.23220

Yuan Zhou, Jing Huang, Xi Yu, Xin Jiang, Yaoyao Shi, Yuanyuan Weng, Yue Kuai, Lizhen Lei, Guoping Ren, Xiaowen Feng, Guoping Zhong, Qingmeng Liu, Hongyang Pan, Xinxia Zhang, Ren Zhou,  and Caide Lu
3131-3142
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Salvaged allogeneic hematopoietic stem cell transplantation for pediatric chemotherapy refractory acute leukemia

Salvaged allogeneic hematopoietic stem cell transplantation for pediatric chemotherapy refractory acute leukemia

https://doi.org/10.18632/oncotarget.22809

Jingbo Wang, Lei Yuan, Haoyu Cheng, Xinhong Fei, Yumin Yin, Jiangying Gu, Song Xue, Junbao He, Fan Yang, Xiaocan Wang, Yixin Yang,  and Weijie Zhang
3143-3159
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The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping

The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping

https://doi.org/10.18632/oncotarget.23223

Chatrin Chatrin, Sandeep K. Talapatra, Bruno Canard,  and Frank Kozielski
3160-3171
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Suppression of FGFR3- and MYC-dependent oncogenesis by tubacin: association with HDAC6-dependent and independent activities

Suppression of FGFR3- and MYC-dependent oncogenesis by tubacin: association with HDAC6-dependent and independent activities

https://doi.org/10.18632/oncotarget.22816

Sara Ota, Zi-Qiang Zhou,  and Peter J. Hurlin
3172-3187
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hypoxia-inducible factor-1α activates transforming growth factor-β1/Smad signaling and increases collagen deposition in dermal fibroblasts

Hypoxia-inducible factor-1α activates transforming growth factor-β1/Smad signaling and increases collagen deposition in dermal fibroblasts

https://doi.org/10.18632/oncotarget.23225

Xu Mingyuan, Pang Qianqian, Xu Shengquan, Ye Chenyi, Lei Rui, Shen Yichen,  and Xu Jinghong
3188-3197
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Systematic analysis of gene expression alterations and clinical outcomes of STAT3 in cancer

Systematic analysis of gene expression alterations and clinical outcomes of STAT3 in cancer

https://doi.org/10.18632/oncotarget.23226

Xiangrong Cui, Xuan Jing, Qin Yi, Chunlan Long, Bin Tan, Xin Li, Xueni Chen, Yue Huang, Zhongping Xiang, Jie Tian,  and Jing Zhu
3198-3213
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Individual and combined effect of TP53, MDM2, MDM4, MTHFR, CCR5, and CASP8 gene polymorphisms in lung cancer

Individual and combined effect of TP53, MDM2, MDM4, MTHFR, CCR5, and CASP8 gene polymorphisms in lung cancer

https://doi.org/10.18632/oncotarget.22756

Ausra Stumbryte, Zivile Gudleviciene, Gabrielis Kundrotas, Daiva Dabkeviciene, Agne Kunickaite,  and Saulius Cicenas
3214-3229
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Reduced QSOX1 enhances radioresistance in nasopharyngeal carcinoma

Reduced QSOX1 enhances radioresistance in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.23227

Lei Zhou, Hong-Min Chen, Song Qu, Ling Li, Wei Zhao, Zhong-Guo Liang, Bin-Bin Yu, Kai-Hua Chen, Qi-Teng Lu, Guo-Xiang Lin,  and Xiao-Dong Zhu
3230-3241
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Greater low-density lipoprotein cholesterol variability is associated with increased progression to dialysis in patients with chronic kidney disease stage 3

Greater low-density lipoprotein cholesterol variability is associated with increased progression to dialysis in patients with chronic kidney disease stage 3

https://doi.org/10.18632/oncotarget.23228

Yu-Hsuan Lin, Jiun-Chi Huang, Pei-Yu Wu, Szu-Chia Chen, Yi-Wen Chiu, Jer-Ming Chang,  and Hung-Chun Chen
3242-3253
Abstract  |  PDF  |  HTML  |  Order a Reprint

Global view of a drug-sensitivity gene network

Global view of a drug-sensitivity gene network

https://doi.org/10.18632/oncotarget.23229

Haixiu Yang, Yunpeng Zhang, Jiasheng Wang, Tan Wu, Siyao Liu, Yanjun Xu,  and Desi Shang
3254-3266
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ovatodiolide targets chronic myeloid leukemia stem cells by epigenetically upregulating hsa-miR-155, suppressing the BCR-ABL fusion gene and dysregulating the PI3K/AKT/mTOR pathway

Ovatodiolide targets chronic myeloid leukemia stem cells by epigenetically upregulating hsa-miR-155, suppressing the BCR-ABL fusion gene and dysregulating the PI3K/AKT/mTOR pathway

https://doi.org/10.18632/oncotarget.23231

Yue-Xing Tu, Shi-Bing Wang, Luo-Qin Fu, Shuang-Shuang Li, Qian-Peng Guo, Yi Wu, Xiao-Zhou Mou,  and Xiang-Min Tong
3267-3277
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Vitexin induces apoptosis by suppressing autophagy in multi-drug resistant colorectal cancer cells

Vitexin induces apoptosis by suppressing autophagy in multi-drug resistant colorectal cancer cells

https://doi.org/10.18632/oncotarget.22890

Monika Bhardwaj, Hee Jun Cho, Souren Paul, Rekha Jakhar, Imran Khan, Seon-Jin Lee, Bo-Yeon Kim, Manigandan Krishnan, Tejinder Pal Khaket, Hee Gu Lee,  and Sun Chul Kang
3278-3291
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BAFF and APRIL expression as an autoimmune signature of membranous nephropathy

BAFF and APRIL expression as an autoimmune signature of membranous nephropathy

https://doi.org/10.18632/oncotarget.23232

Seung Seok Han, Seung Hee Yang, Hyung Ah Jo, Yun Jung Oh, Minkyoung Park, Joo Young Kim, Hajeong Lee, Jung Pyo Lee, Sang-Ho Lee, Kwon Wook Joo, Chun Soo Lim, Yon Su Kim,  and Dong Ki Kim
3292-3302
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Specific alterations in gut microbiota are associated with prognosis of Budd–Chiari syndrome

Specific alterations in gut microbiota are associated with prognosis of Budd–Chiari syndrome

https://doi.org/10.18632/oncotarget.23234

Yu-Ling Sun, Wen-Qi Li, Peng-Xu Ding, Zhi-Wei Wang, Chang-Hua Wei, Xiu-Xian Ma, Rui-Fang Zhang, Yan Wu, Lin Zhou, Ruo-Peng Liang, Yan-Peng Zhang, Yi-Pu Zhao, Rong-Tao Zhu,  and Jian Li
3303-3320
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preclinical study of a Kv11.1 potassium channel activator as antineoplastic approach for breast cancer

Preclinical study of a Kv11.1 potassium channel activator as antineoplastic approach for breast cancer

https://doi.org/10.18632/oncotarget.22925

Daniela F. Fukushiro-Lopes, Alexandra D. Hegel, Vidhya Rao, Debra Wyatt, Andrew Baker, Eun-Kyoung Breuer, Clodia Osipo, Jeremiah J. Zartman, Miranda Burnette, Simon Kaja, Dimitrios Kouzoukas, Sarah Burris, W. Keith Jones,  and Saverio Gentile
3321-3337
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Enhanced anti-tumor efficacy and mechanisms associated with docetaxel-piperine combination- in vitro and in vivo investigation using a taxane-resistant prostate cancer model

Enhanced anti-tumor efficacy and mechanisms associated with docetaxel-piperine combination- in vitro and in vivo investigation using a taxane-resistant prostate cancer model

https://doi.org/10.18632/oncotarget.23235

Chenrui Li, Zhijun Wang, Qian Wang, Rebecca Lucinda Ka Yan Ho, Ying Huang, Moses S.S. Chow, Christopher Wai Kei Lam,  and Zhong Zuo
3338-3352
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Del17p does not always significantly influence the survival of B-cell chronic lymphoproliferative disorders

Del17p does not always significantly influence the survival of B-cell chronic lymphoproliferative disorders

https://doi.org/10.18632/oncotarget.23261

Shuhua Yi, Zengjun Li, Dehui Zou, Wenjie Xiong, Heng Li, Rui Cui, Chengwen Li, Yuting Yan, Wei Liu, Rui Lv, Zhen Yu, Weiwei Chen, Yan Xu, Gang An, Huijun Wang, Kun Ru, Tao Cheng, Jianxiang Wang,  and Lugui Qiu
3353-3364
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MAGE-A11 is activated through TFCP2/ZEB1 binding sites de-methylation as well as histone modification and facilitates ESCC tumor growth

MAGE-A11 is activated through TFCP2/ZEB1 binding sites de-methylation as well as histone modification and facilitates ESCC tumor growth

https://doi.org/10.18632/oncotarget.22973

Shina Liu, Fei Liu, Weina Huang, Lina Gu, Lingjiao Meng, Yingchao Ju, Yunyan Wu, Juan Li, Lihua Liu,  and Meixiang Sang
3365-3378
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Thiotepa-busulfan-fludarabine compared to busulfan-fludarabine for sibling and unrelated donor transplant in acute myeloid leukemia in first remission

Thiotepa-busulfan-fludarabine compared to busulfan-fludarabine for sibling and unrelated donor transplant in acute myeloid leukemia in first remission

https://doi.org/10.18632/oncotarget.23273

Francesco Saraceni, Myriam Labopin, Rose-Marie Hamladji, Ghulam Mufti, Gerard Socié, Avichai Shimoni, Jeremy Delage, Eric Deconinck, Patrice Chevallier, Didier Blaise, Jaime Sanz, Anne Huynh, Edouard Forcade, Bipin N. Savani, Mohamad Mohty, Arnon Nagler,  and Acute Leukemia Working Party of the European society for Blood and Marrow Transplantation (EBMT)
3379-3393
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Copy number profiles of paired primary and metastatic colorectal cancers

Copy number profiles of paired primary and metastatic colorectal cancers

https://doi.org/10.18632/oncotarget.23277

Futoshi Kawamata, Ann-Marie Patch, Katia Nones, Catherine Bond, Diane McKeone, Sally-Ann Pearson, Shigenori Homma, Cheng Liu, Lochlan Fennell, Troy Dumenil, Gunter Hartel, Nozomi Kobayasi, Hideki Yokoo, Moto Fukai, Hiroshi Nishihara, Toshiya Kamiyama, Matthew E. Burge, Christos S. Karapetis, Akinobu Taketomi, Barbara Leggett, Nicola Waddell,  and Vicki Whitehall
3394-3405
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hyperplastic thymus with increased angiogenesis is correlated with elevated serum thyroglobulin level in differentiated thyroid cancer patients with TENIS syndrome

Hyperplastic thymus with increased angiogenesis is correlated with elevated serum thyroglobulin level in differentiated thyroid cancer patients with TENIS syndrome

https://doi.org/10.18632/oncotarget.23281

Guangjian Zhang, Rui Gao, Yuanbo Wang, Yan Liu, Juan Li, Xi Jia, Yiqian Liang,  and Aimin Yang
3406-3416
Abstract  |  PDF  |  HTML  |  Order a Reprint

Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia

Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia

https://doi.org/10.18632/oncotarget.23283

Gaetano Sodaro, Elena Cesaro, Giorgia Montano, Giancarlo Blasio, Federica Fiorentino, Simona Romano, Arnaud Jacquel, Patrick Aurberger,  and Paola Costanzo
3417-3431
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interleukin-34 sustains pro-tumorigenic signals in colon cancer tissue

Interleukin-34 sustains pro-tumorigenic signals in colon cancer tissue

https://doi.org/10.18632/oncotarget.23289

Eleonora Franzè, Vicenzo Dinallo, Angela Rizzo, Martina Di Giovangiulio, Gerolamo Bevivino, Carmine Stolfi, Flavio Caprioli, Alfredo Colantoni, Angela Ortenzi, Antonio Di Grazia, Giuseppe Sica, Pier Paolo Sileri, Piero Rossi,  and Giovanni Monteleone
3432-3445
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MUC1 induces M2 type macrophage influx during postpartum mammary gland involution and triggers breast cancer

MUC1 induces M2 type macrophage influx during postpartum mammary gland involution and triggers breast cancer

https://doi.org/10.18632/oncotarget.23316

Yuan Li, Zhi Pang, Xinran Dong, Xiaodong Liao, Huayun Deng, Chunhua Liao, Yahui Liao, Guoqiang Chen,  and Lei Huang
3446-3458
Abstract  |  PDF  |  HTML  |  Order a Reprint

Brain- and brain tumor-penetrating disulfiram nanoparticles: Sequence of cytotoxic events and efficacy in human glioma cell lines and intracranial xenografts

Brain- and brain tumor-penetrating disulfiram nanoparticles: Sequence of cytotoxic events and efficacy in human glioma cell lines and intracranial xenografts

https://doi.org/10.18632/oncotarget.23320

Hanumantha Rao Madala, Surendra R. Punganuru, Francis Ali-Osman, Ruiwen Zhang,  and Kalkunte S. Srivenugopal
3459-3482
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel cooperative pathway of c-Myc and Furin, a pro-protein convertase, in cell proliferation as a therapeutic target in ovarian cancers

Novel cooperative pathway of c-Myc and Furin, a pro-protein convertase, in cell proliferation as a therapeutic target in ovarian cancers

https://doi.org/10.18632/oncotarget.23322

Junko Hasegawa-Minato, Masafumi Toyoshima, Masumi Ishibashi, Xuewei Zhang, Shogo Shigeta, Carla Grandori, Kazuyuki Kitatani,  and Nobuo Yaegashi
3483-3496
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chronic activation profile of circulating CD8+ T cells in Sézary syndrome

Chronic activation profile of circulating CD8+ T cells in Sézary syndrome

https://doi.org/10.18632/oncotarget.23334

Marina Passos Torrealba, Kelly Cristina Manfrere, Denis R. Miyashiro, Josenilson F. Lima, M. Oliveira, Nátalli Z. Pereira, Jade Cury-Martins, Juliana Pereira, Alberto J.S. Duarte, Maria N. Sato,  and José A. Sanches
3497-3506
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Drug-induced ciliogenesis in pancreatic cancer cells is facilitated by the secreted ATP-purinergic receptor signaling pathway

Drug-induced ciliogenesis in pancreatic cancer cells is facilitated by the secreted ATP-purinergic receptor signaling pathway

https://doi.org/10.18632/oncotarget.23335

Niamat Ali Khan, Abhishek D. Garg, Patrizia Agostinis,  and Johannes V. Swinnen
3507-3518
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LncRNA Gas5 acts as a ceRNA to regulate PTEN expression by sponging miR-222-3p in papillary thyroid carcinoma

LncRNA Gas5 acts as a ceRNA to regulate PTEN expression by sponging miR-222-3p in papillary thyroid carcinoma

https://doi.org/10.18632/oncotarget.23336

Xiao-Fang Zhang, Yan Ye,  and Shu-Jun Zhao
3519-3530
Abstract  |  PDF  |  HTML  |  Order a Reprint

Melatonin attenuated brain death tissue extract-induced cardiac damage by suppressing DAMP signaling

Melatonin attenuated brain death tissue extract-induced cardiac damage by suppressing DAMP signaling

https://doi.org/10.18632/oncotarget.23180

Pei-Hsun Sung, Fan-Yen Lee, Ling-Chun Lin, Kuan-Hung Chen, Hung-Sheng Lin, Pei-Lin Shao, Yi-Chen Li, Yi-Ling Chen, Kun-Chen Lin, Chun-Man Yuen, Hsueh-Wen Chang, Mel S. Lee,  and Hon-Kan Yip
3531-3548
Abstract  |  PDF  |  HTML  |  Order a Reprint

Phosphatase of regenerating liver-3 is expressed in acute lymphoblastic leukemia and mediates leukemic cell adhesion, migration and drug resistance

Phosphatase of regenerating liver-3 is expressed in acute lymphoblastic leukemia and mediates leukemic cell adhesion, migration and drug resistance

https://doi.org/10.18632/oncotarget.23186

Magnus A. Hjort, Pegah Abdollahi, Esten N. Vandsemb, Mona H. Fenstad, Bendik Lund, Tobias S. Slørdahl, Magne Børset,  and Torstein B. Rø
3549-3561
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interferon β protects against avascular osteonecrosis through interleukin 6 inhibition and silent information regulator transcript-1 upregulation

Interferon β protects against avascular osteonecrosis through interleukin 6 inhibition and silent information regulator transcript-1 upregulation

https://doi.org/10.18632/oncotarget.23337

Kyoung Min Kim, Sajeev Wagle, Young Jae Moon, Sung Il Wang, Byung-Hyun Park, Kyu Yun Jang,  and Jung Ryul Kim
3562-3575
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of tumor growth by cancer vaccine combined with metronomic chemotherapy and anti-PD-1 in a pre-clinical setting

Inhibition of tumor growth by cancer vaccine combined with metronomic chemotherapy and anti-PD-1 in a pre-clinical setting

https://doi.org/10.18632/oncotarget.23181

Annacarmen Petrizzo, Angela Mauriello, Antonio Luciano, Domenica Rea, Antonio Barbieri, Claudio Arra, Piera Maiolino, Marialina Tornesello, Vincenzo Gigantino, Gerardo Botti, Gennaro Ciliberto, Franco M. Buonaguro, Maria Tagliamonte,  and Luigi Buonaguro
3576-3589
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FoxM1 and β-catenin predicts aggressiveness in Middle Eastern ovarian cancer and their co-targeting impairs the growth of ovarian cancer cells

FoxM1 and β-catenin predicts aggressiveness in Middle Eastern ovarian cancer and their co-targeting impairs the growth of ovarian cancer cells

https://doi.org/10.18632/oncotarget.23338

Poyil Pratheeshkumar, Sasidharan Padmaja Divya, Sandeep Kumar Parvathareddy, Norah M. Alhoshani, Ismail A. Al-Badawi, Asma Tulbah, Fouad Al-Dayel, Abdul K. Siraj,  and Khawla S. Al-Kuraya
3590-3604
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combined effects of PLK1 and RAS in hepatocellular carcinoma reveal rigosertib as promising novel therapeutic "dual-hit" option

Combined effects of PLK1 and RAS in hepatocellular carcinoma reveal rigosertib as promising novel therapeutic "dual-hit" option

https://doi.org/10.18632/oncotarget.23188

Peter Dietrich, Kim Freese, Abdo Mahli, Wolfgang Erwin Thasler, Claus Hellerbrand,  and Anja Katrin Bosserhoff
3605-3618
Abstract  |  PDF  |  HTML  |  Order a Reprint

Salinomycin inhibits cholangiocarcinoma growth by inhibition of autophagic flux

Salinomycin inhibits cholangiocarcinoma growth by inhibition of autophagic flux

https://doi.org/10.18632/oncotarget.23339

Johannes Klose, Engin Guerlevik, Tina Trostel, Florian Kühnel, Thomas Schmidt, Martin Schneider,  and Alexis Ulrich
3619-3630
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A spliced form of CD44 expresses the unique glycan that is recognized by the prostate cancer specific antibody F77

A spliced form of CD44 expresses the unique glycan that is recognized by the prostate cancer specific antibody F77

https://doi.org/10.18632/oncotarget.23341

Xi Chen, Yasuhiro Nagai, Zhiqiang Zhu, Hang Ruan, Donna M. Peehl, Mark I. Greene,  and Hongtao Zhang
3631-3640
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epithelial-mesenchymal crosstalk induces radioresistance in HNSCC cells

Epithelial-mesenchymal crosstalk induces radioresistance in HNSCC cells

https://doi.org/10.18632/oncotarget.23248

Teresa Bernadette Steinbichler, Abdelmoez Alshaimaa, Metzler Veronika Maria, Dejaco Daniel, Riechelmann Herbert, Dudas Jozsef,  and Skvortsova Ira-Ida
3641-3652
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cognition, serum BDNF levels, and BDNF Val66Met polymorphism in type 2 diabetes patients and healthy controls

Cognition, serum BDNF levels, and BDNF Val66Met polymorphism in type 2 diabetes patients and healthy controls

https://doi.org/10.18632/oncotarget.23342

Yan-Feng Zhen, Xing-Yu Liu, Dong-Hao Zhou, Xiangdong Du, Guangzhong Yin, Yingyang Zhang, Hui Fang, Gang Xu, Jair C. Soares,  and Xiang Yang Zhang
3653-3662
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inhibition of integrin β1-mediated oncogenic signalling by the antitumor microRNA-29 family in head and neck squamous cell carcinoma

Inhibition of integrin β1-mediated oncogenic signalling by the antitumor microRNA-29 family in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.23194

Keiichi Koshizuka, Naoko Kikkawa, Toyoyuki Hanazawa, Yasutaka Yamada, Atsushi Okato, Takayuki Arai, Koji Katada, Yoshitaka Okamoto,  and Naohiko Seki
3663-3676
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Polymorphisms of long non-coding RNA HOTAIR with breast cancer susceptibility and clinical outcomes for a southeast Chinese Han population

Polymorphisms of long non-coding RNA HOTAIR with breast cancer susceptibility and clinical outcomes for a southeast Chinese Han population

https://doi.org/10.18632/oncotarget.23343

Yuxiang Lin, Wenhui Guo, Neng Li, Fangmeng Fu, Songping Lin,  and Chuan Wang
3677-3689
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Androgen receptor/let-7a signaling regulates breast tumor-initiating cells

Androgen receptor/let-7a signaling regulates breast tumor-initiating cells

https://doi.org/10.18632/oncotarget.23196

Wei Zhang, Xiaozhen Liu, Shan Liu, Ying Qin, Xiaoqi Tian, Fengting Niu, Han Liu, Ning Liu,  and Yun Niu
3690-3703
Abstract  |  PDF  |  HTML  |  Order a Reprint

Integrating the dysregulated inflammasome-based molecular functionome in the malignant transformation of endometriosis-associated ovarian carcinoma

Integrating the dysregulated inflammasome-based molecular functionome in the malignant transformation of endometriosis-associated ovarian carcinoma

https://doi.org/10.18632/oncotarget.23364

Chia-Ming Chang, Mong-Lien Wang, Kai-Hsi Lu, Yi-Ping Yang, Chi-Mou Juang, Peng-Hui Wang, Ren-Jun Hsu, Mu-Hsien Yu,  and Cheng-Chang Chang
3704-3726
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Molecular mechanisms of calcium signaling in the modulation of small intestinal ion transports and bicarbonate secretion

Molecular mechanisms of calcium signaling in the modulation of small intestinal ion transports and bicarbonate secretion

https://doi.org/10.18632/oncotarget.23197

Xin Yang, Guorong Wen, Biguang Tuo, Fenglian Zhang, Hanxing Wan, Jialin He, Shiming Yang,  and Hui Dong
3727-3740
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Therapeutic effect of nerve growth factor on canine cerebral infarction evaluated by MRI

Therapeutic effect of nerve growth factor on canine cerebral infarction evaluated by MRI

https://doi.org/10.18632/oncotarget.23345

Yong Wang, Hui Zhang, Zhe Wang, Huaijun Liu, Xin Tian, Jian Yu,  and Chaoxu Chen
3741-3751
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Downregulation of N6-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N6-methyladenosine levels

Downregulation of N6-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N6-methyladenosine levels

https://doi.org/10.18632/oncotarget.23365

Jiangfeng Li, Shuai Meng, Mingjie Xu, Song Wang, Liujia He, Xin Xu, Xiao Wang,  and Liping Xie
3752-3764
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PM2.5 inhalation induces intracranial atherosclerosis which may be ameliorated by omega 3 fatty acids

PM2.5 inhalation induces intracranial atherosclerosis which may be ameliorated by omega 3 fatty acids

https://doi.org/10.18632/oncotarget.23347

Longfei Guan, Xiaokun Geng, Jiamei Shen, James Yip, Fengwu Li, Huishan Du, Zhili Ji,  and Yuchuan Ding
3765-3778
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reduced recruitment of 53BP1 during interstrand crosslink repair is associated with genetically inherited attenuation of mitomycin C sensitivity in a family with Fanconi anemia

Reduced recruitment of 53BP1 during interstrand crosslink repair is associated with genetically inherited attenuation of mitomycin C sensitivity in a family with Fanconi anemia

https://doi.org/10.18632/oncotarget.23375

Emilie Lesport, Alina Ferster, Armand Biver, Benoit Roch, Nadia Vasquez, Nada Jabado, Francina Langa Vives, Patrick Revy, Jean Soulier,  and Jean-Pierre de Villartay
3779-3793
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Betulinic acid impairs metastasis and reduces immunosuppressive cells in breast cancer models

Betulinic acid impairs metastasis and reduces immunosuppressive cells in breast cancer models

https://doi.org/10.18632/oncotarget.23376

An-Qi Zeng, Yan Yu, Yu-Qin Yao, Fang-Fang Yang, Mengya Liao, Lin-Jiang Song, Ya-Li Li, Yang Yu, Yu-Jue Li, Yuan-Le Deng, Shu-Ping Yang, Chen-Juan Zeng, Ping Liu, Yong-Mei Xie, Jin-Liang Yang, Yi-Wen Zhang, Ting-Hong Ye,  and Yu-Quan Wei
3794-3804
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Similarity and difference in tumor-infiltrating lymphocytes in original tumor tissues and those of in vitro expanded populations in head and neck cancer

Similarity and difference in tumor-infiltrating lymphocytes in original tumor tissues and those of in vitro expanded populations in head and neck cancer

https://doi.org/10.18632/oncotarget.23454

Lili Ren, Tatsuo Matsuda, Boya Deng, Kazuma Kiyotani, Taigo Kato, Jae-Hyun Park, Tanguy Y. Seiwert, Everett E. Vokes, Nishant Agrawal,  and Yusuke Nakamura
3805-3814
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth

The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth

https://doi.org/10.18632/oncotarget.23378

Kimberley Hanson, Stephen R. Robinson, Karamallah Al-Yousuf, Adam E. Hendry, Darren W. Sexton, Victoria Sherwood,  and Grant N. Wheeler
3815-3829
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-27b directly targets Rab3D to inhibit the malignant phenotype in colorectal cancer

MiR-27b directly targets Rab3D to inhibit the malignant phenotype in colorectal cancer

https://doi.org/10.18632/oncotarget.23237

Yang Luo, Shi-Yong Yu, Jian-Jun Chen, Jun Qin, Yi-Er Qiu, Ming Zhong,  and Min Chen
3830-3841
Abstract  |  PDF  |  HTML  |  Order a Reprint

Design of miRNA sponges for MDV-1 as a therapeutic strategy against lymphomas

Design of miRNA sponges for MDV-1 as a therapeutic strategy against lymphomas

https://doi.org/10.18632/oncotarget.23379

Yuan Fang, Yuqi Zhou, Yun Zhang, Liangliang He, Chunyi Xue,  and Yongchang Cao
3842-3852
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of survivin as a promising target for the immunotherapy of adult B-cell acute lymphoblastic leukemia

Identification of survivin as a promising target for the immunotherapy of adult B-cell acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.23380

Laurie Freire Boullosa, Payalben Savaliya, Stephanie Bonney, Laurence Orchard, Hannah Wickenden, Cindy Lee, Evelien Smits, Alison H. Banham, Ken I. Mills, Kim Orchard,  and Barbara-Ann Guinn
3853-3866
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Rs2459976 in ZW10 gene associated with congenital heart diseases in Chinese Han population

Rs2459976 in ZW10 gene associated with congenital heart diseases in Chinese Han population

https://doi.org/10.18632/oncotarget.23240

Chao-Yu Sun, Chi Sun, Rui Cheng, Shuai Shi, Ying Han, Xue-Qi Li, Ji-Xin Zhi, Fei-Feng Li,  and Shu-Lin Liu
3867-3874
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Efficacy of assessing circulating cell-free DNA using a simple fluorescence assay in patients with triple-negative breast cancer receiving neoadjuvant chemotherapy: a prospective observational study

Efficacy of assessing circulating cell-free DNA using a simple fluorescence assay in patients with triple-negative breast cancer receiving neoadjuvant chemotherapy: a prospective observational study

https://doi.org/10.18632/oncotarget.23520

Kwonoh Park, Miyoung Woo, Jeong Eun Kim, Jin-Hee Ahn, Kyung Hae Jung, Jin Roh, Gyungyub Gong,  and Sung-Bae Kim
3875-3886
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Catalpol protects mice against Lipopolysaccharide/D-galactosamine-induced acute liver injury through inhibiting inflammatory and oxidative response

Catalpol protects mice against Lipopolysaccharide/D-galactosamine-induced acute liver injury through inhibiting inflammatory and oxidative response

https://doi.org/10.18632/oncotarget.23242

Haogang Zhang, Ruichun Jia, Fujing Wang, Gongcai Qiu, Pengfei Qiao, Xunzheng Xu,  and Dequan Wu
3887-3894
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nucleoside reverse transcriptase inhibitor-induced rat oocyte dysfunction and low fertility mediated by autophagy

Nucleoside reverse transcriptase inhibitor-induced rat oocyte dysfunction and low fertility mediated by autophagy

https://doi.org/10.18632/oncotarget.23243

Li Tang, Shengfu Yang, Huawei Wang, Hai Gu, Xueshan Xia, Yue Feng, Zexing Yang, Shuhua Zhao, Cunmei Su, Zhenfang Su,  and Kunhua Wang
3895-3907
Abstract  |  PDF  |  HTML  |  Order a Reprint

Combination of a hypomethylating agent and inhibitors of PARP and HDAC traps PARP1 and DNMT1 to chromatin, acetylates DNA repair proteins, down-regulates NuRD and induces apoptosis in human leukemia and lymphoma cells

Combination of a hypomethylating agent and inhibitors of PARP and HDAC traps PARP1 and DNMT1 to chromatin, acetylates DNA repair proteins, down-regulates NuRD and induces apoptosis in human leukemia and lymphoma cells

https://doi.org/10.18632/oncotarget.23386

Benigno C. Valdez, Yang Li, David Murray, Yan Liu, Yago Nieto, Richard E. Champlin,  and Borje S. Andersson
3908-3921
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Differential regulation of the androgen receptor by protein phosphatase regulatory subunits

Differential regulation of the androgen receptor by protein phosphatase regulatory subunits

https://doi.org/10.18632/oncotarget.22883

James Grey, Dominic Jones, Laura Wilson, Sirintra Nakjang, Jake Clayton, Richard Temperley, Emma Clark, Luke Gaughan,  and Craig Robson
3922-3935
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Decrease in PSCA expression caused by Helicobacter pylori infection may promote progression to severe gastritis

Decrease in PSCA expression caused by Helicobacter pylori infection may promote progression to severe gastritis

https://doi.org/10.18632/oncotarget.23278

Osamu Toyoshima, Chizu Tanikawa, Ryuta Yamamoto, Hidenobu Watanabe, Hiroharu Yamashita, Kosuke Sakitani, Shuntaro Yoshida, Michiaki Kubo, Keitaro Matsuo, Hidemi Ito, Kazuhiko Koike, Yasuyuki Seto,  and Koichi Matsuda
3936-3945
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Validation of a hypoxia related gene signature in multiple soft tissue sarcoma cohorts

Validation of a hypoxia related gene signature in multiple soft tissue sarcoma cohorts

https://doi.org/10.18632/oncotarget.23280

Lingjian Yang, Laura Forker, Joely J. Iram, Nischalan Pillay, Ananya Choudhury,  and Catharine M. L. West
3946-3955
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Primary breast diffuse large B-cell lymphoma: a population-based study from 1975 to 2014

Primary breast diffuse large B-cell lymphoma: a population-based study from 1975 to 2014

https://doi.org/10.18632/oncotarget.23285

Yijun Jia, Chenbo Sun, Zebing Liu, Weige Wang,  and Xiaoyan Zhou
3956-3967
Abstract  |  PDF  |  HTML  |  Order a Reprint

Impact of STAT3 phosphorylation in glioblastoma stem cells radiosensitization and patient outcome

Impact of STAT3 phosphorylation in glioblastoma stem cells radiosensitization and patient outcome

https://doi.org/10.18632/oncotarget.23374

Konstantin Masliantsev, Baptiste Pinel, Anaïs Balbous, Pierre-Olivier Guichet, Gaëlle Tachon, Serge Milin, Julie Godet, Mathilde Duchesne, Antoine Berger, Christos Petropoulos, Michel Wager,  and Lucie Karayan-Tapon
3968-3979
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Investigation on outcomes and bacterial distributions of liver cirrhosis patients with gram-negative bacterial bloodstream infection

Investigation on outcomes and bacterial distributions of liver cirrhosis patients with gram-negative bacterial bloodstream infection

https://doi.org/10.18632/oncotarget.23582

Yangxin Xie, Bo Tu, Xin Zhang, Jingfeng Bi, Lei Shi, Peng Zhao, Weiwei Chen, Suxia Liu, Dongping Xu,  and Enqiang Qin
3980-3995
Abstract  |  PDF  |  HTML  |  Order a Reprint

Proteomic profiling of antibody-inducing immunogens in tumor tissue identifies PSMA1, LAP3, ANXA3, and maspin as colon cancer markers

Proteomic profiling of antibody-inducing immunogens in tumor tissue identifies PSMA1, LAP3, ANXA3, and maspin as colon cancer markers

https://doi.org/10.18632/oncotarget.23583

Qian Yang, Michael H. Roehrl,  and Julia Y. Wang
3996-4019
Abstract  |  PDF  |  HTML  |  Order a Reprint

Up-regulation of hexokinase II contributes to rituximab-chemotherapy resistance and is a clinically relevant target for therapeutic development

Up-regulation of hexokinase II contributes to rituximab-chemotherapy resistance and is a clinically relevant target for therapeutic development

https://doi.org/10.18632/oncotarget.23425

Juan J. Gu, Anil Singh, Kai Xue, Cory Mavis, Matthew Barth, Vivek Yanamadala, Peter Lenz, Michael Grau, Georg Lenz, Myron S. Czuczman,  and Francisco J. Hernandez-Ilizaliturri
4020-4033
Abstract  |  PDF  |  HTML  |  Order a Reprint

Optimal time of tumour response evaluation and effectiveness of hypofractionated proton beam therapy for inoperable or recurrent hepatocellular carcinoma

Optimal time of tumour response evaluation and effectiveness of hypofractionated proton beam therapy for inoperable or recurrent hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.23428

Tae Hyun Kim, Joong-Won Park, Bo Hyun Kim, Dae Yong Kim, Sung Ho Moon, Sang Soo Kim, Ju Hee Lee, Sang Myung Woo, Young-Hwan Koh, Woo Jin Lee,  and Chang-Min Kim
4034-4043
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells

Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells

https://doi.org/10.18632/oncotarget.23661

Melissa Hodeib, Martin P. Ogrodzinski, Laurent Vergnes, Karen Reue, Beth Y. Karlan, Sophia Y. Lunt,  and Paul-Joseph P. Aspuria
4044-4060
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical outcomes and differential effects of PI3K pathway mutation in obese versus non-obese patients with cervical cancer

Clinical outcomes and differential effects of PI3K pathway mutation in obese versus non-obese patients with cervical cancer

https://doi.org/10.18632/oncotarget.23664

Perry Grigsby, Adnan Elhammali, Fiona Ruiz, Stephanie Markovina, Michael D. McLellan, Christopher A. Miller, Anupama Chundury, Ngoc-Anh L. Ta, Ramachandran Rashmi, John D. Pfeifer, Robert S. Fulton, Todd DeWees,  and Julie K. Schwarz
4061-4073
Abstract  |  PDF  |  HTML  |  Order a Reprint

Transcriptome profiling identified differentially expressed genes and pathways associated with tamoxifen resistance in human breast cancer

Transcriptome profiling identified differentially expressed genes and pathways associated with tamoxifen resistance in human breast cancer

https://doi.org/10.18632/oncotarget.23694

Xin Men, Jun Ma, Tong Wu, Junyi Pu, Shaojia Wen, Jianfeng Shen, Xun Wang, Yamin Wang, Chao Chen,  and Penggao Dai
4074-4089
Abstract  |  PDF  |  HTML  |  Order a Reprint

The vascular disrupting agent combretastatin A-4 phosphate causes prolonged elevation of proteins involved in heme flux and function in resistant tumor cells

The vascular disrupting agent combretastatin A-4 phosphate causes prolonged elevation of proteins involved in heme flux and function in resistant tumor cells

https://doi.org/10.18632/oncotarget.23734

Sanchareeka Dey, Sharda Kumari, Sarada Preeta Kalainayakan, James Campbell III, Poorva Ghosh, Heling Zhou, Keely E. FitzGerald, Maoping Li, Ralph P. Mason, Li Zhang,  and Li Liu
4090-4101
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pulmonary sarcomatoid carcinoma: University of Cincinnati experience

Pulmonary sarcomatoid carcinoma: University of Cincinnati experience

https://doi.org/10.18632/oncotarget.23468

Nagla Abdel Karim, James Schuster, Ihab Eldessouki, Ola Gaber, Tariq Namad, Jiang Wang, Changchun Xie,  and John C. Morris
4102-4108
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cancer immunogenomic approach to neoantigen discovery in a checkpoint blockade responsive murine model of oral cavity squamous cell carcinoma

Cancer immunogenomic approach to neoantigen discovery in a checkpoint blockade responsive murine model of oral cavity squamous cell carcinoma

https://doi.org/10.18632/oncotarget.23751

Paul Zolkind, Dariusz Przybylski, Nemanja Marjanovic, Lan Nguyen, Tianxiang Lin, Tanner Johanns, Anton Alexandrov, Liye Zhou, Clint T. Allen, Alexander P. Miceli, Robert D. Schreiber, Maxim Artyomov, Gavin P. Dunn,  and Ravindra Uppaluri
4109-4119
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HLA class I loss and PD-L1 expression in lung cancer: impact on T-cell infiltration and immune escape

HLA class I loss and PD-L1 expression in lung cancer: impact on T-cell infiltration and immune escape

https://doi.org/10.18632/oncotarget.23469

Francisco Perea, Abel Sánchez-Palencia, Mercedes Gómez-Morales, Mónica Bernal, Ángel Concha, Míguela Méndez García, Amanda Rocío González-Ramírez, Martin Kerick, Javier Martin, Federico Garrido, Francisco Ruiz-Cabello,  and Natalia Aptsiauri
4120-4133
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Potential for subsets of wt-NPM1 primary AML blasts to respond to retinoic acid treatment

Potential for subsets of wt-NPM1 primary AML blasts to respond to retinoic acid treatment

https://doi.org/10.18632/oncotarget.23642

Rodica P. Bunaciu, Robert J. MacDonald, Feng Gao, Lynn M. Johnson, Jeffrey D. Varner, Xin Wang, Sarah Nataraj, Monica L. Guzman,  and Andrew Yen
4134-4149
Abstract  |  PDF  |  HTML  |  Order a Reprint

Effect of NET-1 siRNA conjugated sub-micron bubble complex combined with low-frequency ultrasound exposure in gene transfection

Effect of NET-1 siRNA conjugated sub-micron bubble complex combined with low-frequency ultrasound exposure in gene transfection

https://doi.org/10.18632/oncotarget.23646

Bolin Wu, Xitian Liang, Hui Jing, Xue Han, Yixin Sun, Cunli Guo, Ying Liu,  and Wen Cheng
4150-4160
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ophiopogonin B sensitizes TRAIL-induced apoptosis through activation of autophagy flux and downregulates cellular FLICE-like inhibitory protein

Ophiopogonin B sensitizes TRAIL-induced apoptosis through activation of autophagy flux and downregulates cellular FLICE-like inhibitory protein

https://doi.org/10.18632/oncotarget.23647

Uddin MD. Nazim, Jae-Kyo Jeong,  and Sang-Youel Park
4161-4172
Abstract  |  PDF  |  HTML  |  Order a Reprint

CKS1 expression in melanocytic nevi and melanoma

CKS1 expression in melanocytic nevi and melanoma

https://doi.org/10.18632/oncotarget.23648

Anna A. Brożyna, Andrew Aplin, Cynthia Cohen, Grant Carlson, Andrew Joseph Page, Michael Murphy, Andrzej T. Slominski,  and J. Andrew Carlson
4173-4187
Abstract  |  PDF  |  HTML  |  Order a Reprint

Germline polymorphism of interferon-lambda3 is clinically associated with progression of renal cell carcinoma

Germline polymorphism of interferon-lambda3 is clinically associated with progression of renal cell carcinoma

https://doi.org/10.18632/oncotarget.23683

Akinori Nukui, Yoshiaki Yanai, Toyonori Tsuzuki, Hideyuki Abe, Kyoko Arai, Ken-Ichiro Yoshida,  and Takao Kamai
4188-4199
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association between CYP17 T-34C rs743572 and breast cancer risk

Association between CYP17 T-34C rs743572 and breast cancer risk

https://doi.org/10.18632/oncotarget.23688

Jing Sun, Hong Zhang, Meiyan Gao, Zhishu Tang, Dongyan Guo, Xiaofei Zhang, Zhu Wang, Ruiping Li, Yan Liu, Wansen Sun,  and Xi Sun
4200-4213
Abstract  |  PDF  |  HTML  |  Order a Reprint

A plasma telomeric cell-free DNA level in unaffected women with BRCA1 or/and BRCA2 mutations: a pilot study

A plasma telomeric cell-free DNA level in unaffected women with BRCA1 or/and BRCA2 mutations: a pilot study

https://doi.org/10.18632/oncotarget.23767

Shatovisha Dey, Natascia Marino, Kanokwan Bishop, Paige N. Dahlgren, Aditi Shendre, Anna Maria Storniolo, Chunyan He,  and Hiromi Tanaka
4214-4222
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oxidative stress promotes exit from the stem cell state and spontaneous neuronal differentiation

Oxidative stress promotes exit from the stem cell state and spontaneous neuronal differentiation

https://doi.org/10.18632/oncotarget.23786

Qidong Hu, Puja Khanna, Belinda Shu Ee Wong, Zealyn Shi Lin Heng, Charannya Sozheesvari Subhramanyam, Lal Zo Thanga, Sharon Wui Sing Tan,  and Gyeong Hun Baeg
4223-4238
Abstract  |  PDF  |  HTML  |  Order a Reprint

Meta-Analysis

The efficacy and safety of anti-PD-1/PD-L1 antibody therapy versus docetaxel for pretreated advanced NSCLC: a meta-analysis

The efficacy and safety of anti-PD-1/PD-L1 antibody therapy versus docetaxel for pretreated advanced NSCLC: a meta-analysis

https://doi.org/10.18632/oncotarget.23279

Guanghong Huang, Xin Sun, Dapeng Liu, Yunfeng Zhang, Boxiang Zhang, Guodong Xiao, Xiang Li, Xiao Gao, Chenhao Hu, Meng Wang, Hong Ren,  and Sida Qin
4239-4248
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Meta-analysis of three genome-wide association studies identifies two loci that predict survival and treatment outcome in breast cancer

Meta-analysis of three genome-wide association studies identifies two loci that predict survival and treatment outcome in breast cancer

https://doi.org/10.18632/oncotarget.22747

Sofia Khan, Rainer Fagerholm, Latha Kadalayil, William Tapper, Kristiina Aittomäki, Jianjun Liu, Carl Blomqvist, Diana Eccles,  and Heli Nevanlinna
4249-4257
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The prognostic value of p62 in solid tumor patients: a meta-analysis

The prognostic value of p62 in solid tumor patients: a meta-analysis

https://doi.org/10.18632/oncotarget.23101

Haihua Ruan, Jingyue Xu, Lingling Wang, Zhenyu Zhao, Lingqin Kong, Bei Lan,  and Xichuan Li
4258-4266
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Which type of congenital malformations is significantly increased in singleton pregnancies following after in vitro fertilization/intracytoplasmic sperm injection: a systematic review and meta-analysis

Which type of congenital malformations is significantly increased in singleton pregnancies following after in vitro fertilization/intracytoplasmic sperm injection: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.23689

Ying Liang, Letao Chen, Hong Yu, Hua Wang, Qi Li, Renhe Yu,  and Jiabi Qin
4267-4278
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